given just one laser treatment. The success of the microparticles in eradicating tumors and prolonging survival in animal models holds promise for future treatments in human patients. The polymer used in these microparticles, polycaprolactone, is biocompatible and has already been FDA-approved for
December 24, 2024 at 5:07 PM
given just one laser treatment. The success of the microparticles in eradicating tumors and prolonging survival in animal models holds promise for future treatments in human patients. The polymer used in these microparticles, polycaprolactone, is biocompatible and has already been FDA-approved for
What a wonderful material polycaprolactone is. Non-toxic, biodegradable, 60°C meltable, biocompatible, light, flexible, strong, cools to rock solid, cheap, low scent, low heat transfer so can be hand shaped when heat-softened, autoclave to make pourable casting, machineable, paintable, etc.
April 8, 2025 at 9:43 PM
What a wonderful material polycaprolactone is. Non-toxic, biodegradable, 60°C meltable, biocompatible, light, flexible, strong, cools to rock solid, cheap, low scent, low heat transfer so can be hand shaped when heat-softened, autoclave to make pourable casting, machineable, paintable, etc.
Zwar sind bereits mehrere Bakterien bekannt, die Kunststoff-abbauende Enzyme bilden, in dieser Studie wurde das nun aber auch in einem klinisch relevanten Keim nachgewiesen. Konkret können diese Pseudomonas Stämme Polycaprolactone abbauen 2/
May 14, 2025 at 5:54 PM
Zwar sind bereits mehrere Bakterien bekannt, die Kunststoff-abbauende Enzyme bilden, in dieser Studie wurde das nun aber auch in einem klinisch relevanten Keim nachgewiesen. Konkret können diese Pseudomonas Stämme Polycaprolactone abbauen 2/
Clinical isolate of 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 🦠 eats plastic used in IV and urinary catheters
PA-W23 degrades medical-grade polycaprolactone (PCL) by 78% in just 7 days—using it as its sole carbon source
Worse yet—the plastic diet enhances biofilm formation
𝘾𝙀𝙇𝙇 𝙍𝙀𝙋𝙊𝙍𝙏𝙎
www.cell.com/cell-reports...
PA-W23 degrades medical-grade polycaprolactone (PCL) by 78% in just 7 days—using it as its sole carbon source
Worse yet—the plastic diet enhances biofilm formation
𝘾𝙀𝙇𝙇 𝙍𝙀𝙋𝙊𝙍𝙏𝙎
www.cell.com/cell-reports...
May 12, 2025 at 6:41 PM
Clinical isolate of 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 🦠 eats plastic used in IV and urinary catheters
PA-W23 degrades medical-grade polycaprolactone (PCL) by 78% in just 7 days—using it as its sole carbon source
Worse yet—the plastic diet enhances biofilm formation
𝘾𝙀𝙇𝙇 𝙍𝙀𝙋𝙊𝙍𝙏𝙎
www.cell.com/cell-reports...
PA-W23 degrades medical-grade polycaprolactone (PCL) by 78% in just 7 days—using it as its sole carbon source
Worse yet—the plastic diet enhances biofilm formation
𝘾𝙀𝙇𝙇 𝙍𝙀𝙋𝙊𝙍𝙏𝙎
www.cell.com/cell-reports...
The polycaprolactone splint application was safe and efficacious for treating aural hematoma in dogs and cats, whether localized or generalized, initial or recurrent. Open access article: jav.ma/pcl
February 12, 2025 at 9:24 PM
The polycaprolactone splint application was safe and efficacious for treating aural hematoma in dogs and cats, whether localized or generalized, initial or recurrent. Open access article: jav.ma/pcl
Scientists have discovered that the hospital superbug Pseudomonas aeruginosa can digest medical plastic using an enzyme called Pap1. Found in a 2025 study by Brunel University London, the bacteria breaks down polycaprolactone (PCL)—a plastic used in devices like surgical mesh and wound dressings.
July 21, 2025 at 10:01 PM
Scientists have discovered that the hospital superbug Pseudomonas aeruginosa can digest medical plastic using an enzyme called Pap1. Found in a 2025 study by Brunel University London, the bacteria breaks down polycaprolactone (PCL)—a plastic used in devices like surgical mesh and wound dressings.
Can new scaffolds enhance cardiac tissue engineering? Research on MoS2 integrated membranes shows promise for cell attachment and cardiac gene expression. Is this the future of heart repair? #TissueEngineering #CardiacHealth
www.rimpacts.com/rd/p?c=10074... 📄DOI: doi.org/10.1177/0885...
www.rimpacts.com/rd/p?c=10074... 📄DOI: doi.org/10.1177/0885...
Decellularized Human Amniotic Membrane Reinforced by Mos2-Polycaprolactone Nanofibers, a Novel Conductive Scaffold for Cardiac Tissue Engineering
Can new scaffolds enhance cardiac tissue engineering? Research on MoS2 integrated membranes shows promise for cell attachment and cardiac gene expression. Is this the future of heart repair? #TissueEn...
www.rimpacts.com
September 27, 2026 at 11:35 AM
Can new scaffolds enhance cardiac tissue engineering? Research on MoS2 integrated membranes shows promise for cell attachment and cardiac gene expression. Is this the future of heart repair? #TissueEngineering #CardiacHealth
www.rimpacts.com/rd/p?c=10074... 📄DOI: doi.org/10.1177/0885...
www.rimpacts.com/rd/p?c=10074... 📄DOI: doi.org/10.1177/0885...
Kicking off 2025 with a publication! This collab btw @drwillerth.bsky.social & @TheElviraLab explores atRA’s effect on smart bioinks. Proud to share co-first authorship with Maria Hangad, my undergrad mentee during my PhD @uvic.bsky.social. Full paper here 👉 onlinelibrary.wiley.com/doi/10.1002/...
Investigating How All‐Trans Retinoic Acid Polycaprolactone (atRA‐PCL) Microparticles Alter the Material Properties of 3D Printed Fibrin Constructs
The presence of all-trans retinoic acid (atRA) in polycaprolactone (PCL) microparticles can promote the degradation of fibrin constructs. This highlights the need for a more careful consideration of ...
onlinelibrary.wiley.com
January 22, 2025 at 2:18 PM
Kicking off 2025 with a publication! This collab btw @drwillerth.bsky.social & @TheElviraLab explores atRA’s effect on smart bioinks. Proud to share co-first authorship with Maria Hangad, my undergrad mentee during my PhD @uvic.bsky.social. Full paper here 👉 onlinelibrary.wiley.com/doi/10.1002/...
Pseudomonas aeruginosa clinical isolates can encode plastic-degrading enzymes that allow survival on plastic and augment biofilm formation
This strain encodes a polyesterase that degrades polycaprolactone, and it can use it as a sole carbon source:
www.cell.com/cell-reports...
This strain encodes a polyesterase that degrades polycaprolactone, and it can use it as a sole carbon source:
www.cell.com/cell-reports...
Pseudomonas aeruginosa clinical isolates can encode plastic-degrading enzymes that allow survival on plastic and augment biofilm formation
Howard et al. demonstrate that clinical isolates of the opportunistic pathogen Pseudomonas
aeruginosa can encode functional plastic-degrading enzymes and that these enzymes
can influence bacterial bio...
www.cell.com
May 8, 2025 at 9:06 PM
Pseudomonas aeruginosa clinical isolates can encode plastic-degrading enzymes that allow survival on plastic and augment biofilm formation
This strain encodes a polyesterase that degrades polycaprolactone, and it can use it as a sole carbon source:
www.cell.com/cell-reports...
This strain encodes a polyesterase that degrades polycaprolactone, and it can use it as a sole carbon source:
www.cell.com/cell-reports...
Multilayer bioabsorbable vascular stent with oxidized starch-Fe3O4 nanoparticles and polycaprolactone nanofibers shows strong mechanics and biocompatibility. Fabricated via #electrospinning and #LaserCutting for advanced cardiovascular care. #Biomaterials #Nanotech www.nature.com/articles/s41...
Fabrication of a multilayer bioabsorbable composite vascular stent utilizing oxidized starch-Fe3O4 nanoparticles and polycaprolactone nanofibers - Scientific Reports
Scientific Reports - Fabrication of a multilayer bioabsorbable composite vascular stent utilizing oxidized starch-Fe3O4 nanoparticles and polycaprolactone nanofibers
www.nature.com
July 26, 2025 at 8:19 AM
Multilayer bioabsorbable vascular stent with oxidized starch-Fe3O4 nanoparticles and polycaprolactone nanofibers shows strong mechanics and biocompatibility. Fabricated via #electrospinning and #LaserCutting for advanced cardiovascular care. #Biomaterials #Nanotech www.nature.com/articles/s41...
“Using plate clearing assays, we demonstrated that P. stutzeri is capable of degrading both polyurethane (Impranil®) and polycaprolactone (PCL). Pseudomonas stutzeri also grew on carbon-free agar supplemented with polystyrene”👇🏼😳
A sequence- and structure-based characterization of microbial enzymes identifies P. stutzeri as a plastic-degrading species https://www.biorxiv.org/content/10.1101/2024.04.12.589142v1
A sequence- and structure-based characterization of microbial enzymes identifies P. stutzeri as a plastic-degrading species https://www.biorxiv.org/content/10.1101/2024.04.12.589142v1
Plastic waste has accumulated rapidly in the past century and is now found throughout every ecosyste
www.biorxiv.org
April 13, 2024 at 6:21 AM
“Using plate clearing assays, we demonstrated that P. stutzeri is capable of degrading both polyurethane (Impranil®) and polycaprolactone (PCL). Pseudomonas stutzeri also grew on carbon-free agar supplemented with polystyrene”👇🏼😳
#OpenSLS: #OpenSource #Arduino-controlled selective #laser #sintering of nylon & #biocompatible #polycaprolactone (PCL):
-produce PCL scaffolds: cell studies
Paper: doi.org/10.1371/jour...
Web: andreasbastian.com/opensls
GitHub: github.com/MillerLabFTW...
#DIYbio #lab #3Dprinting #SLS #instruments
-produce PCL scaffolds: cell studies
Paper: doi.org/10.1371/jour...
Web: andreasbastian.com/opensls
GitHub: github.com/MillerLabFTW...
#DIYbio #lab #3Dprinting #SLS #instruments
June 20, 2025 at 11:49 PM
#OpenSLS: #OpenSource #Arduino-controlled selective #laser #sintering of nylon & #biocompatible #polycaprolactone (PCL):
-produce PCL scaffolds: cell studies
Paper: doi.org/10.1371/jour...
Web: andreasbastian.com/opensls
GitHub: github.com/MillerLabFTW...
#DIYbio #lab #3Dprinting #SLS #instruments
-produce PCL scaffolds: cell studies
Paper: doi.org/10.1371/jour...
Web: andreasbastian.com/opensls
GitHub: github.com/MillerLabFTW...
#DIYbio #lab #3Dprinting #SLS #instruments
Congratulations to @tianlaixia.bsky.social, Laihui Xiao and Neha Yadav for this @natprot.nature.com paper on living CDSA preparation of polycaprolactone-based 2D platelets. doi.org/10.1038/s415... @uobchemistry.bsky.social #chemsky
Preparation of polycaprolactone-based 2D platelets via living crystallization-driven self-assembly - Nature Protocols
Uniform two-dimensional platelets made from synthetic polymers can range in size from 100 nm to several micrometers and have diverse applications. This Protocol describes the synthesis and crystalliza...
doi.org
September 18, 2026 at 9:27 AM
Congratulations to @tianlaixia.bsky.social, Laihui Xiao and Neha Yadav for this @natprot.nature.com paper on living CDSA preparation of polycaprolactone-based 2D platelets. doi.org/10.1038/s415... @uobchemistry.bsky.social #chemsky
A classic melt electrowriting (MEW) video. With a nozzle-collector gap of 3.5 mm, a polycaprolactone melt is extruded to a 5.75kV charged 22G nozzle, thinning out into a fine microfiber. The jet speed is 260mm/min and although the collector speed increases, it never breaks. doi.org/10.1002/admt...
November 20, 2024 at 3:00 PM
A classic melt electrowriting (MEW) video. With a nozzle-collector gap of 3.5 mm, a polycaprolactone melt is extruded to a 5.75kV charged 22G nozzle, thinning out into a fine microfiber. The jet speed is 260mm/min and although the collector speed increases, it never breaks. doi.org/10.1002/admt...
This study explores the fabrication of nanofibrillar scaffolds through the melt electrofibrillation of polycaprolactone to guide myogenic differentiation. The scaffolds provide nanofibrillar cues that promote cell organization and integration, mimicking key features of the ECM
August 29, 2025 at 2:37 PM
This study explores the fabrication of nanofibrillar scaffolds through the melt electrofibrillation of polycaprolactone to guide myogenic differentiation. The scaffolds provide nanofibrillar cues that promote cell organization and integration, mimicking key features of the ECM
surprising absolutely nobody from ID, it's everyone's ""friend"" Pseudomonas aeruginosa again. of which some strains are capable of enzymatically degrading polycaprolactone & using it as sole carbon source: www.cell.com/cell-reports...
May 27, 2025 at 10:01 PM
surprising absolutely nobody from ID, it's everyone's ""friend"" Pseudomonas aeruginosa again. of which some strains are capable of enzymatically degrading polycaprolactone & using it as sole carbon source: www.cell.com/cell-reports...
#new_paper: Micro vs nano: influence of filler size on the rheological and mechanical properties of highly-filled PLA/HAp and PCL/HAp composites
@elsevierconnect.bsky.social: Polylactide (PLA), Polycaprolactone(PCL), Hydroxyapatite(HAp), Morphology, Rheology, Microindentation
doi.org/10.1016/j.jm...
@elsevierconnect.bsky.social: Polylactide (PLA), Polycaprolactone(PCL), Hydroxyapatite(HAp), Morphology, Rheology, Microindentation
doi.org/10.1016/j.jm...
August 14, 2025 at 12:34 PM
#new_paper: Micro vs nano: influence of filler size on the rheological and mechanical properties of highly-filled PLA/HAp and PCL/HAp composites
@elsevierconnect.bsky.social: Polylactide (PLA), Polycaprolactone(PCL), Hydroxyapatite(HAp), Morphology, Rheology, Microindentation
doi.org/10.1016/j.jm...
@elsevierconnect.bsky.social: Polylactide (PLA), Polycaprolactone(PCL), Hydroxyapatite(HAp), Morphology, Rheology, Microindentation
doi.org/10.1016/j.jm...
➡️IPCM news: ipcm.fr/en/latest-pu...
📜👍Latest publication @emoca-ipcm.bsky.social group (@rscsustainability.rsc.org)
Highly efficient hydrogenative depolymerisation of polycaprolactone to 1,6-hexanediol
@sorbonne-universite.fr @cnrs-paris.bsky.social @vonwolffchem.bsky.social
📜👍Latest publication @emoca-ipcm.bsky.social group (@rscsustainability.rsc.org)
Highly efficient hydrogenative depolymerisation of polycaprolactone to 1,6-hexanediol
@sorbonne-universite.fr @cnrs-paris.bsky.social @vonwolffchem.bsky.social
February 20, 2026 at 9:31 AM
➡️IPCM news: ipcm.fr/en/latest-pu...
📜👍Latest publication @emoca-ipcm.bsky.social group (@rscsustainability.rsc.org)
Highly efficient hydrogenative depolymerisation of polycaprolactone to 1,6-hexanediol
@sorbonne-universite.fr @cnrs-paris.bsky.social @vonwolffchem.bsky.social
📜👍Latest publication @emoca-ipcm.bsky.social group (@rscsustainability.rsc.org)
Highly efficient hydrogenative depolymerisation of polycaprolactone to 1,6-hexanediol
@sorbonne-universite.fr @cnrs-paris.bsky.social @vonwolffchem.bsky.social
From #lignin to #bioplastics with non-toxic zinc-guanidine catalysts : check out our new paper in #ChemCatChem : chemistry-europe.onlinelibrary.wiley.com/doi/am-pdf/1...
and the #FAIRdata are deposited here: www.radar-service.eu/radar/en/dat... thanks to @nfdi4chem.de
and the #FAIRdata are deposited here: www.radar-service.eu/radar/en/dat... thanks to @nfdi4chem.de
From Biomass to Polymers: Kinetic Analysis and Sustainable Synthesis of Lignin‐Polycaprolactone Copolymers
Lignin-polycaprolactone (PCL) copolymers were prepared using a highly efficient and nontoxic zinc catalyst. The reaction kinetics were investigated and differ from those usually observed in ring-open...
chemistry-europe.onlinelibrary.wiley.com
July 21, 2025 at 9:41 PM
From #lignin to #bioplastics with non-toxic zinc-guanidine catalysts : check out our new paper in #ChemCatChem : chemistry-europe.onlinelibrary.wiley.com/doi/am-pdf/1...
and the #FAIRdata are deposited here: www.radar-service.eu/radar/en/dat... thanks to @nfdi4chem.de
and the #FAIRdata are deposited here: www.radar-service.eu/radar/en/dat... thanks to @nfdi4chem.de
🕷️ Inspired by Spiders 🕸️
From Spherulites to Strain-Induced Crystals: Process-Driven Crystallinity in Melt Electrospinning Writing of Polycaprolactone
New ASAP in ACS Applied Engineering Materials - Congrats to the authors 🎊
pubs.acs.org/doi/10.1021/...
From Spherulites to Strain-Induced Crystals: Process-Driven Crystallinity in Melt Electrospinning Writing of Polycaprolactone
New ASAP in ACS Applied Engineering Materials - Congrats to the authors 🎊
pubs.acs.org/doi/10.1021/...
March 20, 2026 at 11:09 AM
🕷️ Inspired by Spiders 🕸️
From Spherulites to Strain-Induced Crystals: Process-Driven Crystallinity in Melt Electrospinning Writing of Polycaprolactone
New ASAP in ACS Applied Engineering Materials - Congrats to the authors 🎊
pubs.acs.org/doi/10.1021/...
From Spherulites to Strain-Induced Crystals: Process-Driven Crystallinity in Melt Electrospinning Writing of Polycaprolactone
New ASAP in ACS Applied Engineering Materials - Congrats to the authors 🎊
pubs.acs.org/doi/10.1021/...
Polycaprolactone is a polymer with a very low melting point but it does sounds like a form of HRT that turns you into a goat
April 27, 2024 at 6:34 AM
Polycaprolactone is a polymer with a very low melting point but it does sounds like a form of HRT that turns you into a goat
Multilayer and Biomimetic Polycaprolactone/Uterine ECM Scaffold for Uterine Tissue Engineering and Anti-Adhesion Barrier Applications via 3D-Printing Near-Field Melt Electrowriting https://www.biorxiv.org/content/10.64898/2026.09.13.751266v1
September 15, 2026 at 10:45 PM
Multilayer and Biomimetic Polycaprolactone/Uterine ECM Scaffold for Uterine Tissue Engineering and Anti-Adhesion Barrier Applications via 3D-Printing Near-Field Melt Electrowriting https://www.biorxiv.org/content/10.64898/2026.09.13.751266v1
#new_paper: Aminolyzed polycaprolactone nanofiber scaffolds with visible light-activated sterilization for tissue engineering applications
@pubs.acs.org: nanofiber scaffolds
doi.org/10.1021/acs....
@pubs.acs.org: nanofiber scaffolds
doi.org/10.1021/acs....
Aminolyzed Polycaprolactone Nanofiber Scaffolds with Visible Light-Activated Sterilization for Tissue Engineering Applications
New photoactive nanofiber materials based on an aminolyzed polycaprolactone membrane with demonstrated cytocompatibility were developed. Two photoactive compounds, the photosensitizer Rose Bengal and ...
doi.org
December 18, 2025 at 9:25 AM
#new_paper: Aminolyzed polycaprolactone nanofiber scaffolds with visible light-activated sterilization for tissue engineering applications
@pubs.acs.org: nanofiber scaffolds
doi.org/10.1021/acs....
@pubs.acs.org: nanofiber scaffolds
doi.org/10.1021/acs....
V happy to share the latest collaborative effort between myself & Anthony Callanan, led by #PhDstudent Mary Heim, who characterised #macrophages in the irradiated #thyroid, and then developed electrospun scaffolds to locally modulate immune response.
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation
Radiation-induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate th...
advanced.onlinelibrary.wiley.com
February 4, 2026 at 11:08 AM
V happy to share the latest collaborative effort between myself & Anthony Callanan, led by #PhDstudent Mary Heim, who characterised #macrophages in the irradiated #thyroid, and then developed electrospun scaffolds to locally modulate immune response.
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
This microbe eats one specific plastic, en.wikipedia.org/wiki/Polycap.... A problem, not a catastrophe.
Polycaprolactone - Wikipedia
en.wikipedia.org
May 28, 2025 at 6:41 AM
This microbe eats one specific plastic, en.wikipedia.org/wiki/Polycap.... A problem, not a catastrophe.