We’ve been super happy with our Ultima ppmSeq results. Top notch output
October 19, 2025 at 5:18 AM
We’ve been super happy with our Ultima ppmSeq results. Top notch output
Short-read technology Ultima Genomics (not on Bluesky) published the technical details of their ppmSeq double-strand sequencing method for highly accurate short-read sequencing.
August 18, 2025 at 11:31 AM
Short-read technology Ultima Genomics (not on Bluesky) published the technical details of their ppmSeq double-strand sequencing method for highly accurate short-read sequencing.
Taylor Jensen, Labcorp Oncology: @UltimaGenomics ppmSeq technology + Solaris chemistry on the UG 100 meets the ideal MRD assay in terms of “scalability, cost, throughput and performance” #agbt25
February 25, 2025 at 8:46 PM
Taylor Jensen, Labcorp Oncology: @UltimaGenomics ppmSeq technology + Solaris chemistry on the UG 100 meets the ideal MRD assay in terms of “scalability, cost, throughput and performance” #agbt25
#UG100Solaris by @UltimaGenomics offers cost-efficient sequencing as potential NIH cuts loom. $0.24/M reads, $80/genome enables single-cell, RNA-Seq, spatial transcriptomics, proteomics, meta/epigenetics, ppmSeq, whole genome at scale. #AGBT25 #AGBT2025 #AGBT @agbt
February 25, 2025 at 6:51 PM
#UG100Solaris by @UltimaGenomics offers cost-efficient sequencing as potential NIH cuts loom. $0.24/M reads, $80/genome enables single-cell, RNA-Seq, spatial transcriptomics, proteomics, meta/epigenetics, ppmSeq, whole genome at scale. #AGBT25 #AGBT2025 #AGBT @agbt
Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules. #NGS #ppmSeq #DualStrandSequencing #DNAsequencing #UltimaGenomics #Genomics #Bioinformatics 🧬 🖥️
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 16, 2025 at 2:28 PM
Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules. #NGS #ppmSeq #DualStrandSequencing #DNAsequencing #UltimaGenomics #Genomics #Bioinformatics 🧬 🖥️
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
ppmSeq sounds interesting, anything out there already about it?
January 4, 2024 at 2:39 PM
ppmSeq sounds interesting, anything out there already about it?
But what if you don't have the tumor? DOESN'T MATTER. ppmSeq is so error robust that you don't need tumor sequencing to detect ctDNA. Hello, new era of tumor-naive patient monitoring.
August 14, 2025 at 5:41 PM
But what if you don't have the tumor? DOESN'T MATTER. ppmSeq is so error robust that you don't need tumor sequencing to detect ctDNA. Hello, new era of tumor-naive patient monitoring.
Application 1: tumor-informed ctDNA detection. ppmSeq is perfectly suited for this. We sequence the tumor, and mine for mutations in the blood with ppmSeq. This enabled part per TEN MILLION ctDNA detection. PAR PER 10M. Insanity.
August 14, 2025 at 5:41 PM
Application 1: tumor-informed ctDNA detection. ppmSeq is perfectly suited for this. We sequence the tumor, and mine for mutations in the blood with ppmSeq. This enabled part per TEN MILLION ctDNA detection. PAR PER 10M. Insanity.
ppmSeq is a broad DNA sequencing method. The applications are endless. We looked at 2:
August 14, 2025 at 5:41 PM
ppmSeq is a broad DNA sequencing method. The applications are endless. We looked at 2:
Initial benchmarking shows massive scalability of ppmSeq, ~40-60% of our reads encode dsDNA molecules. The more you sequence, the more get dsDNA
CRAZY STAT: ppmSeq is a PCR-FREE method that works with ONE NANOGRAM of input. ONE!!!
CRAZY STAT: ppmSeq is a PCR-FREE method that works with ONE NANOGRAM of input. ONE!!!
August 14, 2025 at 5:41 PM
Initial benchmarking shows massive scalability of ppmSeq, ~40-60% of our reads encode dsDNA molecules. The more you sequence, the more get dsDNA
CRAZY STAT: ppmSeq is a PCR-FREE method that works with ONE NANOGRAM of input. ONE!!!
CRAZY STAT: ppmSeq is a PCR-FREE method that works with ONE NANOGRAM of input. ONE!!!
Highly accurate sequencing OR high throughput? We refuse to choose.
Introducing ppmSeq, a method built to deliver both. Our latest from the @landau.bsky.social lab with Ultima Genomics
👀👀👀
See ⬇️ for a primer on the next frontier of genomics
www.biorxiv.org/content/10.1...
Introducing ppmSeq, a method built to deliver both. Our latest from the @landau.bsky.social lab with Ultima Genomics
👀👀👀
See ⬇️ for a primer on the next frontier of genomics
www.biorxiv.org/content/10.1...
Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules
Distinguishing real biological variation in the form of single-nucleotide variants (SNVs) from errors is a major challenge for genome sequencing technologies. This is particularly true in settings whe...
www.biorxiv.org
August 14, 2025 at 5:41 PM
Highly accurate sequencing OR high throughput? We refuse to choose.
Introducing ppmSeq, a method built to deliver both. Our latest from the @landau.bsky.social lab with Ultima Genomics
👀👀👀
See ⬇️ for a primer on the next frontier of genomics
www.biorxiv.org/content/10.1...
Introducing ppmSeq, a method built to deliver both. Our latest from the @landau.bsky.social lab with Ultima Genomics
👀👀👀
See ⬇️ for a primer on the next frontier of genomics
www.biorxiv.org/content/10.1...
Ultima Genomics Unveils TRACERx MRD Data and Groundbreaking Sequencing Innovations at AACR 2026#USA#Fremont#Ultima_Genomics#ppmSeq#TRACERx
Ultima Genomics Unveils TRACERx MRD Data and Groundbreaking Sequencing Innovations at AACR 2026
Ultima Genomics showcased significant advancements in ctDNA detection and whole genome sequencing during the MRD Symposium at AACR 2026, setting new standards in cancer monitoring.
third-news.com
April 17, 2026 at 12:21 PM
Ultima Genomics Unveils TRACERx MRD Data and Groundbreaking Sequencing Innovations at AACR 2026#USA#Fremont#Ultima_Genomics#ppmSeq#TRACERx
Ultima Genomics' ppmSeq Technology Revolutionizes Whole-Genome MRD Detection with Unprecedented Sensitivity#United_States#Fremont#cancer_detection#Ultima_Genomics#ppmSeq
Ultima Genomics' ppmSeq Technology Revolutionizes Whole-Genome MRD Detection with Unprecedented Sensitivity
Ultima Genomics introduces their ppmSeq technology, showcasing superior sensitivity and efficiency for detecting minimal residual disease (MRD), surpassing existing clinical methods.
third-news.com
August 14, 2025 at 5:52 PM
Ultima Genomics' ppmSeq Technology Revolutionizes Whole-Genome MRD Detection with Unprecedented Sensitivity#United_States#Fremont#cancer_detection#Ultima_Genomics#ppmSeq
- $100 30X human genomes
- variant calling performance equivalent to industry standards
- ultra accurate PCR-free ppmSeq mode for “needle-in-haystack” problems e.g. tumor-derived cfDNA
- high degree of walk-away, few touch point automation with high reliability
- variant calling performance equivalent to industry standards
- ultra accurate PCR-free ppmSeq mode for “needle-in-haystack” problems e.g. tumor-derived cfDNA
- high degree of walk-away, few touch point automation with high reliability
January 4, 2024 at 1:30 PM
- $100 30X human genomes
- variant calling performance equivalent to industry standards
- ultra accurate PCR-free ppmSeq mode for “needle-in-haystack” problems e.g. tumor-derived cfDNA
- high degree of walk-away, few touch point automation with high reliability
- variant calling performance equivalent to industry standards
- ultra accurate PCR-free ppmSeq mode for “needle-in-haystack” problems e.g. tumor-derived cfDNA
- high degree of walk-away, few touch point automation with high reliability
🧨Exciting new pre-print 🧨 Introducing ppmSeq - cost effective, scalable dual-strand 🧬🧬 sequencing. Scalability & ultra-low error in one! A game changer for somatic genome discovery science and cfDNA clinical apps. Check out thread for deets!
Highly accurate sequencing OR high throughput? We refuse to choose.
Introducing ppmSeq, a method built to deliver both. Our latest from the @landau.bsky.social lab with Ultima Genomics
👀👀👀
See ⬇️ for a primer on the next frontier of genomics
www.biorxiv.org/content/10.1...
Introducing ppmSeq, a method built to deliver both. Our latest from the @landau.bsky.social lab with Ultima Genomics
👀👀👀
See ⬇️ for a primer on the next frontier of genomics
www.biorxiv.org/content/10.1...
Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules
Distinguishing real biological variation in the form of single-nucleotide variants (SNVs) from errors is a major challenge for genome sequencing technologies. This is particularly true in settings whe...
www.biorxiv.org
August 14, 2025 at 6:11 PM
🧨Exciting new pre-print 🧨 Introducing ppmSeq - cost effective, scalable dual-strand 🧬🧬 sequencing. Scalability & ultra-low error in one! A game changer for somatic genome discovery science and cfDNA clinical apps. Check out thread for deets!
