Rapamycin als Medikament bei Abstoßung von Organtransplantaten oder zur Krebstherapie.
„Niedrig dosiertes Rapamycin hat das Potenzial hat, einige der immunologischen oder infektionsbedingten Funktionsstörungen, unter denen viele Menschen leiden, direkt anzugehen“,
„Niedrig dosiertes Rapamycin hat das Potenzial hat, einige der immunologischen oder infektionsbedingten Funktionsstörungen, unter denen viele Menschen leiden, direkt anzugehen“,
October 30, 2024 at 11:21 PM
Rapamycin als Medikament bei Abstoßung von Organtransplantaten oder zur Krebstherapie.
„Niedrig dosiertes Rapamycin hat das Potenzial hat, einige der immunologischen oder infektionsbedingten Funktionsstörungen, unter denen viele Menschen leiden, direkt anzugehen“,
„Niedrig dosiertes Rapamycin hat das Potenzial hat, einige der immunologischen oder infektionsbedingten Funktionsstörungen, unter denen viele Menschen leiden, direkt anzugehen“,
Rapamycin als potenzielle Behandlungsmöglichkeit für Long COVID
»Die PolyBio Research Foundation gab heute eine neue Finanzierung durch den Balvi Fund bekannt, die dazu dienen soll, eine klinische Studie zu beschleunigen, welche niedrig dosiertes Rapamycin als potenzielle Behandlungsmöglichkeit …
»Die PolyBio Research Foundation gab heute eine neue Finanzierung durch den Balvi Fund bekannt, die dazu dienen soll, eine klinische Studie zu beschleunigen, welche niedrig dosiertes Rapamycin als potenzielle Behandlungsmöglichkeit …
Breaking: Funding from Vitalik Buterin’s Balvi Fund Expands Long COVID Low-Dose Rapamycin Clinical Trial with a New Open-Label Phase
1/
1/
May 29, 2026 at 7:54 PM
Rapamycin als potenzielle Behandlungsmöglichkeit für Long COVID
»Die PolyBio Research Foundation gab heute eine neue Finanzierung durch den Balvi Fund bekannt, die dazu dienen soll, eine klinische Studie zu beschleunigen, welche niedrig dosiertes Rapamycin als potenzielle Behandlungsmöglichkeit …
»Die PolyBio Research Foundation gab heute eine neue Finanzierung durch den Balvi Fund bekannt, die dazu dienen soll, eine klinische Studie zu beschleunigen, welche niedrig dosiertes Rapamycin als potenzielle Behandlungsmöglichkeit …
Did you know Rapamycin gets its name from Rapa Nui (Easter Island), where the compound was first discovered in soil samples?
April 20, 2025 at 1:23 AM
Did you know Rapamycin gets its name from Rapa Nui (Easter Island), where the compound was first discovered in soil samples?
👩🔬Polybio announce $800K low-dose Rapamycin treatment trial for #LongCovid
Led by Putrino & Proal 👏
polybio.org/polybio-supp...
Led by Putrino & Proal 👏
polybio.org/polybio-supp...
PolyBio supports & helps conceptualize long COVID rapamycin clinical trial - PolyBio Research Foundation
The trial will test a low dose of the drug rapamycin in participants across a 3-month period. Analysis of participant blood...
polybio.org
October 30, 2024 at 2:33 PM
👩🔬Polybio announce $800K low-dose Rapamycin treatment trial for #LongCovid
Led by Putrino & Proal 👏
polybio.org/polybio-supp...
Led by Putrino & Proal 👏
polybio.org/polybio-supp...
Rapamycin ... not so good for your wounds 🧪 #drosophila #devbio
January 17, 2025 at 3:54 PM
Rapamycin ... not so good for your wounds 🧪 #drosophila #devbio
Klinische Studie zu Rapamycin bei #LongCOVID
Die Studie wird bei CoRE durchgeführt: einer Klinik unter der Leitung von Dr. David Putrino und Dr. Amy Proal von PolyBio.
Im Rahmen der Studie wird eine niedrige Dosis des Medikaments Rapamycin …
#COVID19 #MECFS #SARSCoV2 #Coronavirus
Die Studie wird bei CoRE durchgeführt: einer Klinik unter der Leitung von Dr. David Putrino und Dr. Amy Proal von PolyBio.
Im Rahmen der Studie wird eine niedrige Dosis des Medikaments Rapamycin …
#COVID19 #MECFS #SARSCoV2 #Coronavirus
October 30, 2024 at 11:17 PM
Klinische Studie zu Rapamycin bei #LongCOVID
Die Studie wird bei CoRE durchgeführt: einer Klinik unter der Leitung von Dr. David Putrino und Dr. Amy Proal von PolyBio.
Im Rahmen der Studie wird eine niedrige Dosis des Medikaments Rapamycin …
#COVID19 #MECFS #SARSCoV2 #Coronavirus
Die Studie wird bei CoRE durchgeführt: einer Klinik unter der Leitung von Dr. David Putrino und Dr. Amy Proal von PolyBio.
Im Rahmen der Studie wird eine niedrige Dosis des Medikaments Rapamycin …
#COVID19 #MECFS #SARSCoV2 #Coronavirus
1/1 Nachdem gestern verschiedentlich ja mehr Energie für Kritik an einer Rapamycin Studie investiert wurde, jetzt weitere Infos zur Forschung. @polybiorf.bsky.social unterstützt weitere Forschung und zitiert dabei auch andere Studien zur Wirksamkeit von Rapamycin:
polybio.org/projects/lon...
polybio.org/projects/lon...
Long COVID low-dose rapamycin clinical trial - PolyBio Research Foundation
Project Summary: A double blinded randomized controlled pilot clinical trial to determine if low-dose rapamycin can improve symptoms in patients with...
polybio.org
June 7, 2025 at 7:56 AM
1/1 Nachdem gestern verschiedentlich ja mehr Energie für Kritik an einer Rapamycin Studie investiert wurde, jetzt weitere Infos zur Forschung. @polybiorf.bsky.social unterstützt weitere Forschung und zitiert dabei auch andere Studien zur Wirksamkeit von Rapamycin:
polybio.org/projects/lon...
polybio.org/projects/lon...
Therapeutic Immune Reprogramming by Rapamycin Attenuates Plaque Inflammation and Lymphoid Immune Responses in Aged Atherosclerotic Mice
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Therapeutic Immune Reprogramming by Rapamycin Attenuates Plaque Inflammation and Lymphoid Immune Responses in Aged Atherosclerotic Mice
Rapamycin exerts multifaceted immunomodulatory effects in age-induced atherosclerosis, with pronounced inhibitory effects on adaptive immunity. Rapamycin reduced plaque inflammation and macrophage co...
onlinelibrary.wiley.com
September 27, 2026 at 11:54 AM
Therapeutic Immune Reprogramming by Rapamycin Attenuates Plaque Inflammation and Lymphoid Immune Responses in Aged Atherosclerotic Mice
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
We found a new way to make mice live 30% longer! 🧪 #aging #longevity #rapamycin
A combination of classic longevity drug rapamycin with cancer drug trametinib was more effective than either on its own.
Read more about the exciting results here:
A combination of classic longevity drug rapamycin with cancer drug trametinib was more effective than either on its own.
Read more about the exciting results here:
New drug cocktail makes mice live 30% longer – Andrew Steele
Rapamycin + anti-cancer drug trametinib does better than rapa on its own!
andrewsteele.co.uk
May 31, 2025 at 3:27 PM
We found a new way to make mice live 30% longer! 🧪 #aging #longevity #rapamycin
A combination of classic longevity drug rapamycin with cancer drug trametinib was more effective than either on its own.
Read more about the exciting results here:
A combination of classic longevity drug rapamycin with cancer drug trametinib was more effective than either on its own.
Read more about the exciting results here:
Simmaron’s Rapamycin ME/CFS Trial Moves Forward: The Goal – FDA Approval #MECFS www.healthrising.org/blog/2025/02...
Simmaron's Rapamycin ME/CFS Trial Moves Forward: The Goal - FDA Approval - Health Rising
A successful rapamycin clinical trial in chronic fatigue syndrome (ME/CFS) leads to more studies and perhaps FDA approval
www.healthrising.org
February 3, 2025 at 10:30 PM
Simmaron’s Rapamycin ME/CFS Trial Moves Forward: The Goal – FDA Approval #MECFS www.healthrising.org/blog/2025/02...
Rapamycin-Anwender berichteten auch über keine Fälle von Long COVID, obwohl sie im Durchschnitt 7,5 Jahre älter waren als Nichtanwender. In einer anderen Studie wurde festgestellt, dass die einmal wöchentliche Verabreichung eines Rapamycin-Analogons die Anzeichen einer
October 30, 2024 at 11:20 PM
Rapamycin-Anwender berichteten auch über keine Fälle von Long COVID, obwohl sie im Durchschnitt 7,5 Jahre älter waren als Nichtanwender. In einer anderen Studie wurde festgestellt, dass die einmal wöchentliche Verabreichung eines Rapamycin-Analogons die Anzeichen einer
Today @thesicktimes.org: deep dive from @frogsandstars.bsky.social about two clinical trials testing rapamycin for Long COVID and ME, as well as people's experiences trying the drug off-label. thesicktimes.org/2025/07/29/c...
Clinical trials are testing cancer drug rapamycin for Long COVID and ME - The Sick Times
Two clinical trials are currently underway in the U.S. to evaluate the effect of rapamycin on Long COVID and myalgic encephalomyelitis (ME) — one at Mount Sinai’s Cohen Center for Recovery from Comple...
thesicktimes.org
July 29, 2025 at 5:19 PM
Today @thesicktimes.org: deep dive from @frogsandstars.bsky.social about two clinical trials testing rapamycin for Long COVID and ME, as well as people's experiences trying the drug off-label. thesicktimes.org/2025/07/29/c...
Longevity researchers are taking a generic drug they think may help extend people's lives. Now a dentist is testing if rapamycin stops gum disease — a canary in the coal mine for age-related diseases.
Rapamycin may slow aging. Here's one way the drug will be tested
Longevity researchers are taking a generic drug they think may help extend people's lives. Now a dentist is testing if rapamycin stops gum disease — a canary in the coal mine for age-related diseases.
www.npr.org
July 1, 2024 at 6:01 PM
Longevity researchers are taking a generic drug they think may help extend people's lives. Now a dentist is testing if rapamycin stops gum disease — a canary in the coal mine for age-related diseases.
Just a reminder that our Unraveled episode discussing Rapamycin, Long Covid, ME/CFS is now online:
www.youtube.com/watch?v=W_aw...
www.youtube.com/watch?v=W_aw...
ME/CFS, Long Covid, and Rapamycin
YouTube video by Unraveled: Understanding Complex Illness
www.youtube.com
August 30, 2025 at 4:24 AM
Just a reminder that our Unraveled episode discussing Rapamycin, Long Covid, ME/CFS is now online:
www.youtube.com/watch?v=W_aw...
www.youtube.com/watch?v=W_aw...
The Sick Times: 'Clinical trials are testing cancer drug rapamycin for Long COVID and ME'
'People who have tried the drug off-label in low doses report a range of experiences'
thesicktimes.org/2025/07/29/c...
'People who have tried the drug off-label in low doses report a range of experiences'
thesicktimes.org/2025/07/29/c...
Clinical trials are testing cancer drug rapamycin for Long COVID and ME - The Sick Times
Two clinical trials are currently underway in the U.S. to evaluate the effect of rapamycin on Long COVID and myalgic encephalomyelitis (ME) — one at Mount Sinai’s Cohen Center for Recovery from Comple...
thesicktimes.org
July 29, 2025 at 4:32 PM
The Sick Times: 'Clinical trials are testing cancer drug rapamycin for Long COVID and ME'
'People who have tried the drug off-label in low doses report a range of experiences'
thesicktimes.org/2025/07/29/c...
'People who have tried the drug off-label in low doses report a range of experiences'
thesicktimes.org/2025/07/29/c...
“Metformin, Rapamycin! Rapamycin, Metformin! Let’s call the whole thing off…”
It’s weird - I’ve been hearing one or other of them might prolong life for years…
It’s weird - I’ve been hearing one or other of them might prolong life for years…
Restricting calories has been linked to living longer in many studies, and now it seems that the drug rapamycin has nearly the same effect, at least in animals
Rapamycin seems to boost longevity as effectively as eating less
Restricting calories has been linked to living longer in many studies, and now it seems that the drug rapamycin has nearly the same effect, at least in animals
www.newscientist.com
July 2, 2025 at 11:51 AM
“Metformin, Rapamycin! Rapamycin, Metformin! Let’s call the whole thing off…”
It’s weird - I’ve been hearing one or other of them might prolong life for years…
It’s weird - I’ve been hearing one or other of them might prolong life for years…
Dr. Akiko Iwasaki an der Yale University geschickt, wo durch Analysen ermittelt wird, wie sich die Verwendung von Rapamycin auf Teile der Immunantwort auswirkt. Auch die hormonelle Signalübertragung wird bei den Teilnehmern gemessen. Rapamycin ist ein von der FDA
October 30, 2024 at 11:19 PM
Dr. Akiko Iwasaki an der Yale University geschickt, wo durch Analysen ermittelt wird, wie sich die Verwendung von Rapamycin auf Teile der Immunantwort auswirkt. Auch die hormonelle Signalübertragung wird bei den Teilnehmern gemessen. Rapamycin ist ein von der FDA
In mice, the additive effect of 2 drugs for extending lifespan and healthspan: rapamycin and trametinib, a MEK blocker used for cancer treatment @nataging.nature.com
www.nature.com/articles/s43...
www.nature.com/articles/s43...
May 28, 2025 at 1:22 PM
In mice, the additive effect of 2 drugs for extending lifespan and healthspan: rapamycin and trametinib, a MEK blocker used for cancer treatment @nataging.nature.com
www.nature.com/articles/s43...
www.nature.com/articles/s43...
“If this finding holds up with further research, clinicians could use blood tests to screen patients for potential treatment with rapamycin, which ‘would be a huge advance,’ said… trial participant @chromatowski.bsky.social, a member of PLRC” #LongCovid #SevereME thesicktimes.org/2025/07/29/c...
Clinical trials are testing cancer drug rapamycin for Long COVID and ME - The Sick Times
Two clinical trials are currently underway in the U.S. to evaluate the effect of rapamycin on Long COVID and myalgic encephalomyelitis (ME) — one at Mount Sinai’s Cohen Center for Recovery from Comple...
thesicktimes.org
August 8, 2025 at 9:08 PM
“If this finding holds up with further research, clinicians could use blood tests to screen patients for potential treatment with rapamycin, which ‘would be a huge advance,’ said… trial participant @chromatowski.bsky.social, a member of PLRC” #LongCovid #SevereME thesicktimes.org/2025/07/29/c...
For what it’s worth, I have both Long Covid and pre-Covid ME and feel I’ve seen noticeable benefit from rapamycin (I’m in Simmaron’s ME trial of it).
We’re truly excited that the PolyBio supported Low-dose Rapamycin trial is now recruiting in the NYC area.
Interested in learning more? Here’s the full study summary: polybio.org/projects/lon...
Interested in learning more? Here’s the full study summary: polybio.org/projects/lon...
April 15, 2025 at 9:53 PM
For what it’s worth, I have both Long Covid and pre-Covid ME and feel I’ve seen noticeable benefit from rapamycin (I’m in Simmaron’s ME trial of it).
I’ve updated this post to note that the TRPM8-rapamycin connection had been published by another research group as well!
Never assume that you know all about what any drug molecule is doing in the body - where it's going, what it's binding to. A new example:
Rapamycin's Secrets
www.science.org
October 21, 2025 at 2:00 PM
I’ve updated this post to note that the TRPM8-rapamycin connection had been published by another research group as well!
Health Rising: “Simmaron’s Rapamycin ME/CFS Trial Moves Forward: The Goal – FDA Approval”
“Gunnar reported that with most of the results in, a significant percentage of patients were considered responders.”
www.healthrising.org/blog/2025/02...
“Gunnar reported that with most of the results in, a significant percentage of patients were considered responders.”
www.healthrising.org/blog/2025/02...
Simmaron's Rapamycin ME/CFS Trial Moves Forward: The Goal - FDA Approval - Health Rising
A successful rapamycin clinical trial in chronic fatigue syndrome (ME/CFS) leads to more studies and perhaps FDA approval
www.healthrising.org
February 2, 2025 at 5:54 PM
Health Rising: “Simmaron’s Rapamycin ME/CFS Trial Moves Forward: The Goal – FDA Approval”
“Gunnar reported that with most of the results in, a significant percentage of patients were considered responders.”
www.healthrising.org/blog/2025/02...
“Gunnar reported that with most of the results in, a significant percentage of patients were considered responders.”
www.healthrising.org/blog/2025/02...
A cheap drug used by longevity enthusiasts may have a surprising impact [read: HARM] on exercise wapo.st/4cYnIY3
Those taking rapamycin gained LESS strength & physical function.
"They also developed more aches, fatigue and, in one case, a serious infection."
Sum: Don't take "rapamycin off-label."
Those taking rapamycin gained LESS strength & physical function.
"They also developed more aches, fatigue and, in one case, a serious infection."
Sum: Don't take "rapamycin off-label."
A cheap drug used by longevity enthusiasts may have a surprising impact on exercise
Researchers anticipated rapamycin would enhance the effects of working out, while also initiating health improvements of its own, but that wasn’t the case.
wapo.st
April 29, 2026 at 4:50 PM
A cheap drug used by longevity enthusiasts may have a surprising impact [read: HARM] on exercise wapo.st/4cYnIY3
Those taking rapamycin gained LESS strength & physical function.
"They also developed more aches, fatigue and, in one case, a serious infection."
Sum: Don't take "rapamycin off-label."
Those taking rapamycin gained LESS strength & physical function.
"They also developed more aches, fatigue and, in one case, a serious infection."
Sum: Don't take "rapamycin off-label."