#solidcancers
We welcome applicants with expertise in the #biology of #SolidCancers, #TumourImmunology, #CancerEvolution, & computational/ #ML approaches to #tumour ecosystems; but we encourage visionary proposals from across the spectrum of #CancerResearch that complement & expand our existing strengths

#CanSky
New Group Leader Recruitment Now Open (MI/25/54) | Cancer Research UK Manchester Institute
We are seeking to appoint exceptional early-career scientists, including clinician scientists, as Group Leaders to develop bold, innovative, and high-impact research programmes.
www.cruk.manchester.ac.uk
September 24, 2025 at 3:03 PM
The Gersch Group developed a well characterized matched chemical pair of inhibitor and degrader for the investigation of the DUB USP7 in #solidcancers together with the Cancer Center at the University Hospital Essen. Congrats to @nikolasklink.bsky.social et al.

www.nature.com/articles/s41...
Targeted degradation of USP7 in solid cancer cells reveals distinct effects of deubiquitinase degraders and inhibitors - Nature Communications
DUBs regulate key cellular processes, but selective tools are scarce. Here, the authors developed PROTACs for the DUB USP7, comparing degraders with inhibitors. The study provides a valuable toolbox f...
www.nature.com
May 19, 2026 at 10:35 AM
IL-15 improves the effectiveness of GPC3 CAR T cells in targeting solid tumors

Read more: www.news-medical.net/news/2024120...

#cancer #solidcancers #tumour
IL-15 improves the effectiveness of GPC3 CAR T cells in targeting solid tumors
The study reveals IL-15's role in enhancing GPC3 CAR T cell therapy, improving tumor targeting and T cell survival in patients with solid cancers.
www.news-medical.net
December 2, 2024 at 3:43 PM