#supergenes
In my only science talk ever, I spent HOURS beating my head against how to visually demonstrate supergenes in sparrows. Like, that was probably the hardest work of the whole presentation.
November 28, 2025 at 5:35 PM
Lethal epistasis maintains strong linkage disequilibrium between unlinked supergenes https://www.biorxiv.org/content/10.64898/2026.01.08.698410v1
January 9, 2026 at 3:32 AM
New preprint! We investigated the evolution of supergenes and mechanisms underlying distyly in Linum species that diverged ca 33 Mya. 1/8
bsky.app/profile/bior...
April 18, 2025 at 11:26 AM
#ERGAReads | Distinct genomic architectures but the same gene underlie the convergent evolution of a plant supergene 🌸🧬
www.science.org/doi/10.1126/...
#genomes #plantgenomics #evolution #supergenes #comparativegenomics

@gpotente.bsky.social
Distinct genomic architectures but the same gene underlie the convergent evolution of a plant supergene
High-quality genome assemblies from multiple plant species reveal different paths of evolution in supergenes.
www.science.org
September 30, 2026 at 7:30 AM
August 19, 2025 at 1:46 PM
Beyond supergenes: the diverse roles of inversions in trait evolution www.cell.com/trends/ecolo...
Beyond supergenes: the diverse roles of inversions in trait evolution
Chromosomal inversions are ubiquitous across the Tree of Life, with genome-wide studies revealing a bias toward smaller inversions, yet research has disproportionately focused on large, supergene-like...
www.cell.com
September 8, 2025 at 7:21 PM
Supergenes have been found in ants, butterflies, birds, fish, plants and fungi so far, and sex chromosomes may be a special case of them. This is an interesting new understanding of evolutionary units 🧪 🐜 🦋 www.scientificamerican.com/article/how-...
How Supergenes Shape Evolution
By locking together traits that work well together, supergenes provide striking evolutionary advantages. But they can also be costly because they make it nearly impossible to purge bad mutations
www.scientificamerican.com
January 9, 2024 at 2:55 PM
Repeated evolution of supergenes on an ancient social chromosome https://www.biorxiv.org/content/10.1101/2024.12.01.626239v1
Repeated evolution of supergenes on an ancient social chromosome https://www.biorxiv.org/content/10.1101/2024.12.01.626239v1
Supergenes are non-recombining chromosomal regions that code for complex polymorphic traits. With th
www.biorxiv.org
December 2, 2024 at 8:32 AM
This week reading is an interesting 2021 review about Supergenes and their genetic/evolutionary peculiarities from Juanita Gutiérrez-Valencia et al.

I'll go on reading more recent supergenes-related research paper :)

Here is the link: academic.oup.com/gbe/article/...
The Genomic Architecture and Evolutionary Fates of Supergenes
Abstract. Supergenes are genomic regions containing sets of tightly linked loci that control multi-trait phenotypic polymorphisms under balancing selection
academic.oup.com
August 29, 2026 at 11:32 AM
Sequential origin of an alternative colony founding strategy driven by two supergenes in Temnothorax ants academic.oup.com/mbe/article/...
Sequential origin of an alternative colony founding strategy driven by two supergenes in Temnothorax ants
Abstract. Recent discoveries reveal that many complex intraspecific polymorphisms are shaped by a single supergene that maintains coadapted genetic variant
academic.oup.com
May 27, 2026 at 1:43 PM
Stepwise expansion of recombination suppression on sex chromosomes and other supergenes through lower load advantage and deleterious mutation sheltering https://www.biorxiv.org/content/10.1101/2025.06.27.661902v1
July 2, 2025 at 3:32 AM
📄 Repeated evolution of supergenes on an ancient social chromosome 🐜🧬

⬇️
www.cell.com/current-biol...
Repeated evolution of supergenes on an ancient social chromosome
Lajmi et al. describe a novel supergene associated with social structure in desert ants. Surprisingly, this supergene evolved on an ancient chromosome that also evolved an analogous supergene in fire ...
www.cell.com
February 27, 2026 at 12:36 PM
Independently evolved supergenes control colony social organization and queen reproductive strategies in several ant lineages. Sigeman et al. uncover a novel 9 Mb supergene controlling queen size and social organization in Myrmica ruginodis.

🔗 doi.org/10.1093/molbev/msaf255

#evobio #molbio #ants
November 5, 2025 at 11:24 AM
Scientists just found DNA “supergenes” that speed up evolution | ScienceDaily share.google/uxaSMTz7wVf4...
Scientists just found DNA “supergenes” that speed up evolution
Hidden within fish DNA are powerful genetic twists that may explain one of nature’s biggest mysteries: how new species form so quickly. In Lake Malawi, hundreds of cichlid fish species evolved at ligh...
share.google
April 1, 2026 at 6:15 PM
EASYstrata: a new workflow to infer evolutionary strata along sex chromosomes and other supergenes https://www.biorxiv.org/content/10.1101/2025.01.06.631483v1
January 8, 2025 at 12:34 AM
Sigeman et al. used comparative population genomics of 264 individuals from all seven European wood ant species, proposing that selection to escape fitness costs underlies haplotype loss in obligately polygynous wood ants.

🔗 doi.org/10.1093/molbev/msaf320

#evobio #molbio
The loss of a supergene in obligately polygynous Formica wood ant species
Abstract. Some of the most striking examples of phenotypic variation within species are controlled by supergenes. However, most research on supergenes has
doi.org
December 29, 2025 at 6:41 PM
How did nature’s incredible diversity come to be? These cichlid fish may offer a clue 🐠

Cambridge researchers have found that chunks of ‘flipped’ #DNA can help fish quickly adapt to new habitats and evolve into new species, acting as evolutionary ‘superchargers’ 👇
bit.ly/3HGqEN6
June 13, 2025 at 10:27 AM
Jones, @kocherlab.bsky.social @brendanimal.bsky.social et al. investigate gene regulation in the social supergene of the fire ant, finding widespread impacts on chromatin accessibility, enhancer activity, and transcription.

🔗 doi.org/10.1093/molbev/msaf112

#evobio #molbio #bugsky
The Fire Ant Social Chromosome Exerts a Major Influence on Genome Regulation
Abstract. Supergenes underlying complex trait polymorphisms ensure that sets of coadapted alleles remain genetically linked. Despite their prevalence in na
doi.org
June 9, 2025 at 8:52 AM
Hemizygosity has been documented in at least 6 independently evolved distyly supergenes by now… and interestingly, there are plenty of distylous Oleaceae. Check out @paulineraim.bsky.social 🧵 here: bsky.app/profile/paul...
April 15, 2024 at 4:57 PM
Very excited to see our work finally out in GBE.

We explored the evolution of a sex-linked supergene finding evidence that recombination suppression may have led to relaxation of selection, suggesting that whilst adaptive, supergenes may bear molecular costs.

doi.org/10.1093/gbe/...
Molecular Evolution of a Sex-Linked Inversion Polymorphism in Zebra Finches
Abstract. Recent years have seen an explosion in examples of supergenes, where recombination is suppressed between haplotypes, often via inversion polymorp
doi.org
July 17, 2026 at 7:58 PM
Kevin in the back right has the supergenes
February 28, 2024 at 7:46 PM
The final version of our paper on the evolution of supergenes and mechanisms underlying distyly in Linum is now up at New Phytologist doi.org/10.1111/nph....
July 21, 2025 at 4:13 PM