Children with Long COVID had measurable retinal microvascular changes. buff.ly/fPSg320
In 74 kids ages 7–17, scans found wider arterioles, wider venules, and a higher A/V ratio, consistent with endothelial dysfunction.
The eye may help track pediatric Long COVID.
#medsky #pedsky 😷🧪
In 74 kids ages 7–17, scans found wider arterioles, wider venules, and a higher A/V ratio, consistent with endothelial dysfunction.
The eye may help track pediatric Long COVID.
#medsky #pedsky 😷🧪
June 5, 2026 at 6:23 AM
Children with Long COVID had measurable retinal microvascular changes. buff.ly/fPSg320
In 74 kids ages 7–17, scans found wider arterioles, wider venules, and a higher A/V ratio, consistent with endothelial dysfunction.
The eye may help track pediatric Long COVID.
#medsky #pedsky 😷🧪
In 74 kids ages 7–17, scans found wider arterioles, wider venules, and a higher A/V ratio, consistent with endothelial dysfunction.
The eye may help track pediatric Long COVID.
#medsky #pedsky 😷🧪
Here's a fun one for #FluorescenceFriday. Did you know #marsupials have an entirely different CNS vascular anatomy to most animals? Arterioles and venules enter the brain and branch in unison, terminating at capillary loops. Check out this example from a #TasmanianDevil brain! (1/2)
November 29, 2024 at 12:43 AM
Here's a fun one for #FluorescenceFriday. Did you know #marsupials have an entirely different CNS vascular anatomy to most animals? Arterioles and venules enter the brain and branch in unison, terminating at capillary loops. Check out this example from a #TasmanianDevil brain! (1/2)
👁️🧠 The eyes reveal for Alzheimer’s risk
Midlife retinal images (arterioles & venules) can reveal dementia risk before symptoms begin.
Wider venules = higher risk across 7 key domains – from inflammation to lifestyle.
🔗 journals.sagepub.com/doi/10.1177/...
#Dementia #SciComm 🧪
Midlife retinal images (arterioles & venules) can reveal dementia risk before symptoms begin.
Wider venules = higher risk across 7 key domains – from inflammation to lifestyle.
🔗 journals.sagepub.com/doi/10.1177/...
#Dementia #SciComm 🧪
Measures of retinal health successfully capture risk for Alzheimer's disease and related dementias at midlife - Ashleigh Barrett-Young, Aaron Reuben, Avshalom Caspi, Kirsten Cheyne, David Ireland, Jes...
Background Identification of at-risk individuals who would benefit from early intervention for Alzheimer's disease and related dementias (ADRD) is critical...
journals.sagepub.com
April 13, 2025 at 8:27 AM
👁️🧠 The eyes reveal for Alzheimer’s risk
Midlife retinal images (arterioles & venules) can reveal dementia risk before symptoms begin.
Wider venules = higher risk across 7 key domains – from inflammation to lifestyle.
🔗 journals.sagepub.com/doi/10.1177/...
#Dementia #SciComm 🧪
Midlife retinal images (arterioles & venules) can reveal dementia risk before symptoms begin.
Wider venules = higher risk across 7 key domains – from inflammation to lifestyle.
🔗 journals.sagepub.com/doi/10.1177/...
#Dementia #SciComm 🧪
Insomnia Anatomy Academy 7! 🧪 Blood goes out your arteries - arterioles - capillaries - venules - veins, right? Along the way it spreads nutrients and fluids, and reabsorbs them.
Well YES but #notallfluids, because your capillaries miss THREE LITERS per day. What rescues you from swelling? LYMPH
Well YES but #notallfluids, because your capillaries miss THREE LITERS per day. What rescues you from swelling? LYMPH
August 25, 2023 at 2:51 PM
Insomnia Anatomy Academy 7! 🧪 Blood goes out your arteries - arterioles - capillaries - venules - veins, right? Along the way it spreads nutrients and fluids, and reabsorbs them.
Well YES but #notallfluids, because your capillaries miss THREE LITERS per day. What rescues you from swelling? LYMPH
Well YES but #notallfluids, because your capillaries miss THREE LITERS per day. What rescues you from swelling? LYMPH
..in a nutshell tho
‘Children with post-COVID-19 syndrome (PCS) showed significant retinal microvascular abnormalities, including wider arterioles and venules, suggesting persistent endothelial dysfunction months after SARS-CoV-2 infection.’
‘Children with post-COVID-19 syndrome (PCS) showed significant retinal microvascular abnormalities, including wider arterioles and venules, suggesting persistent endothelial dysfunction months after SARS-CoV-2 infection.’
June 8, 2026 at 2:44 PM
..in a nutshell tho
‘Children with post-COVID-19 syndrome (PCS) showed significant retinal microvascular abnormalities, including wider arterioles and venules, suggesting persistent endothelial dysfunction months after SARS-CoV-2 infection.’
‘Children with post-COVID-19 syndrome (PCS) showed significant retinal microvascular abnormalities, including wider arterioles and venules, suggesting persistent endothelial dysfunction months after SARS-CoV-2 infection.’
'Here, we report that Fc-optimized anti-CTLA-4 antibodies are potent remodelers of tumor vasculature that increase tumor-associated high endothelial venules (TA-HEVs), specialized blood vessels supporting lymphocyte entry into tumors'
#Immunology #Immunotherapy
www.cell.com/cell-reports...
#Immunology #Immunotherapy
www.cell.com/cell-reports...
Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade
Blanchard et al. reveal that Fc-optimized anti-CTLA-4 antibodies remodel tumor vasculature
and increase tumor-associated high endothelial venules (TA-HEVs) that support T cell
recruitment into tumors....
www.cell.com
June 6, 2025 at 6:37 AM
'Here, we report that Fc-optimized anti-CTLA-4 antibodies are potent remodelers of tumor vasculature that increase tumor-associated high endothelial venules (TA-HEVs), specialized blood vessels supporting lymphocyte entry into tumors'
#Immunology #Immunotherapy
www.cell.com/cell-reports...
#Immunology #Immunotherapy
www.cell.com/cell-reports...
Insomnia Anatomy Academy 5: 🧪 Your brain has muscle. IS it a muscle? NO. But there's muscle running through it. Because every artery and vein and yea, even arterioles and venules has smooth muscle inside it. So where your blood is, muscle is too. It's kind of romantic.
(Capillaries don't. Too smol)
(Capillaries don't. Too smol)
August 24, 2023 at 2:12 PM
Insomnia Anatomy Academy 5: 🧪 Your brain has muscle. IS it a muscle? NO. But there's muscle running through it. Because every artery and vein and yea, even arterioles and venules has smooth muscle inside it. So where your blood is, muscle is too. It's kind of romantic.
(Capillaries don't. Too smol)
(Capillaries don't. Too smol)
A nice example of florid #IgAVasculitis
📸 1&2 Fibrinoid necrosis of post-capillary venules with leukocytoclasis
📸 3 IgA immunofluorescence
#pathology
#dermatology
#pathsky
😉
📸 1&2 Fibrinoid necrosis of post-capillary venules with leukocytoclasis
📸 3 IgA immunofluorescence
#pathology
#dermatology
#pathsky
😉
December 4, 2024 at 8:27 PM
A nice example of florid #IgAVasculitis
📸 1&2 Fibrinoid necrosis of post-capillary venules with leukocytoclasis
📸 3 IgA immunofluorescence
#pathology
#dermatology
#pathsky
😉
📸 1&2 Fibrinoid necrosis of post-capillary venules with leukocytoclasis
📸 3 IgA immunofluorescence
#pathology
#dermatology
#pathsky
😉
🩸What is the primary function of capillaries?
Capillaries are microscopic vessels connecting arterioles and venules. Their walls are typically only one endothelial cell thick—an important clue when choosing your answer.
💬 Share your answer in the comments!
#Anatomy #MedicalEducation #Physiology
Capillaries are microscopic vessels connecting arterioles and venules. Their walls are typically only one endothelial cell thick—an important clue when choosing your answer.
💬 Share your answer in the comments!
#Anatomy #MedicalEducation #Physiology
September 17, 2026 at 2:46 AM
🩸What is the primary function of capillaries?
Capillaries are microscopic vessels connecting arterioles and venules. Their walls are typically only one endothelial cell thick—an important clue when choosing your answer.
💬 Share your answer in the comments!
#Anatomy #MedicalEducation #Physiology
Capillaries are microscopic vessels connecting arterioles and venules. Their walls are typically only one endothelial cell thick—an important clue when choosing your answer.
💬 Share your answer in the comments!
#Anatomy #MedicalEducation #Physiology
new pomegranate leaves
March 24, 2026 at 5:48 PM
new pomegranate leaves
Study on microvascular contributions to age-related white matter loss has been published in Nature Neuroscience.
In this work, they identify rare, deep-reaching venules called principal cortical venules (PCVs)
www.nature.com/articles/s41...
In this work, they identify rare, deep-reaching venules called principal cortical venules (PCVs)
www.nature.com/articles/s41...
August 15, 2025 at 4:41 PM
Study on microvascular contributions to age-related white matter loss has been published in Nature Neuroscience.
In this work, they identify rare, deep-reaching venules called principal cortical venules (PCVs)
www.nature.com/articles/s41...
In this work, they identify rare, deep-reaching venules called principal cortical venules (PCVs)
www.nature.com/articles/s41...
The post-capillary venules are in the pathological firing line again this evening. Yikes! This one shows florid fibrinoid necrosis while a helpless arteriole looks on.😢
#LeukocytoclasticVasculitis
#pathology
#dermatology
#PathSky
#LeukocytoclasticVasculitis
#pathology
#dermatology
#PathSky
February 20, 2025 at 8:25 PM
The post-capillary venules are in the pathological firing line again this evening. Yikes! This one shows florid fibrinoid necrosis while a helpless arteriole looks on.😢
#LeukocytoclasticVasculitis
#pathology
#dermatology
#PathSky
#LeukocytoclasticVasculitis
#pathology
#dermatology
#PathSky
3) One of the abnormalities found by studying the retina is called venular flicker-induced dilation (fVID). It's how much the diameter of small veins (venules) changes in response to flickering light stimulation.
In Long Covid patients fVID was reduced.
In Long Covid patients fVID was reduced.
February 1, 2026 at 9:05 AM
3) One of the abnormalities found by studying the retina is called venular flicker-induced dilation (fVID). It's how much the diameter of small veins (venules) changes in response to flickering light stimulation.
In Long Covid patients fVID was reduced.
In Long Covid patients fVID was reduced.
Sometimes, poor perfusion is attributed to a Venule🤓
Age-related rarefaction of capillary meshwork converging into principal cortical venules, most pronounced in layer 6/CC➡️
Gliosis+demyelination in 🐭 #WhiteMatterAging
#SciArt
@andyshihlab.bsky.social #NatNeuro 2025
www.nature.com/articles/s41...
Age-related rarefaction of capillary meshwork converging into principal cortical venules, most pronounced in layer 6/CC➡️
Gliosis+demyelination in 🐭 #WhiteMatterAging
#SciArt
@andyshihlab.bsky.social #NatNeuro 2025
www.nature.com/articles/s41...
October 10, 2025 at 11:30 AM
Sometimes, poor perfusion is attributed to a Venule🤓
Age-related rarefaction of capillary meshwork converging into principal cortical venules, most pronounced in layer 6/CC➡️
Gliosis+demyelination in 🐭 #WhiteMatterAging
#SciArt
@andyshihlab.bsky.social #NatNeuro 2025
www.nature.com/articles/s41...
Age-related rarefaction of capillary meshwork converging into principal cortical venules, most pronounced in layer 6/CC➡️
Gliosis+demyelination in 🐭 #WhiteMatterAging
#SciArt
@andyshihlab.bsky.social #NatNeuro 2025
www.nature.com/articles/s41...
#WeekendRead! #EveryCellIsAnImmuneCell! Jacobs, Bergers &co show @cp-immunity.bsky.social that high endothelial venules #HEVs utilize #autophagy to maintain their identity & recruit immune cells to secondary lymphoid organs during inflammation. Inhibiting autophagy in HEVs protects from #psoriasis!
Autophagy maintains high endothelial venule identity and function during inflammation
High endothelial venules (HEVs) facilitate lymphocyte entry into lymph nodes by displaying
peripheral node addressin (PNAd), yet how PNAd is regulated remains poorly understood.
Jacobs et al. reveal t...
www.cell.com
July 25, 2026 at 3:20 PM
#WeekendRead! #EveryCellIsAnImmuneCell! Jacobs, Bergers &co show @cp-immunity.bsky.social that high endothelial venules #HEVs utilize #autophagy to maintain their identity & recruit immune cells to secondary lymphoid organs during inflammation. Inhibiting autophagy in HEVs protects from #psoriasis!
(k)alien
#photography #stunday #kale #alien #magenta #nofilter #eattherainbow #plants
#tooprettytoeat … #butidid
#photography #stunday #kale #alien #magenta #nofilter #eattherainbow #plants
#tooprettytoeat … #butidid
September 21, 2025 at 9:46 PM
5) There's was also a third measure called AVR that looks at the ratio of thickness of the arterioles to that of the venules: the tiny veins that carry blood away from the eye.
This arteriolar-to-venular ratio (AVR) was also lower in patients and correlated with LC severity.
This arteriolar-to-venular ratio (AVR) was also lower in patients and correlated with LC severity.
February 1, 2026 at 9:06 AM
5) There's was also a third measure called AVR that looks at the ratio of thickness of the arterioles to that of the venules: the tiny veins that carry blood away from the eye.
This arteriolar-to-venular ratio (AVR) was also lower in patients and correlated with LC severity.
This arteriolar-to-venular ratio (AVR) was also lower in patients and correlated with LC severity.
Lemon Tree Very Pretty.
Fujifilm X100V
#blackandwhite #blueskyartshow #botanical #dead #frozen #fujifilm #grain #lemontree #monochrome #nature #photography #theartofseeing #tLeIxFaEs #x100v #weather
Fujifilm X100V
#blackandwhite #blueskyartshow #botanical #dead #frozen #fujifilm #grain #lemontree #monochrome #nature #photography #theartofseeing #tLeIxFaEs #x100v #weather
February 16, 2025 at 2:25 AM
Lemon Tree Very Pretty.
Fujifilm X100V
#blackandwhite #blueskyartshow #botanical #dead #frozen #fujifilm #grain #lemontree #monochrome #nature #photography #theartofseeing #tLeIxFaEs #x100v #weather
Fujifilm X100V
#blackandwhite #blueskyartshow #botanical #dead #frozen #fujifilm #grain #lemontree #monochrome #nature #photography #theartofseeing #tLeIxFaEs #x100v #weather
Today's #eyeSCANdy depicts lumen of a vein showing the ostia of several entering venules.
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology
November 22, 2024 at 4:35 PM
Today's #eyeSCANdy depicts lumen of a vein showing the ostia of several entering venules.
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology
In particular, venules were associated with various domains of dementia risk, including subjective health, inflammation, cardiometabolic risk, physical function, sensory function, psychosomatic risk, socioeconomic factors, and lifestyle. So venules may be a good target for quantifying AD risk!
3/4
3/4
March 4, 2025 at 9:48 PM
In particular, venules were associated with various domains of dementia risk, including subjective health, inflammation, cardiometabolic risk, physical function, sensory function, psychosomatic risk, socioeconomic factors, and lifestyle. So venules may be a good target for quantifying AD risk!
3/4
3/4
‘Children with post-COVID-19 syndrome (PCS) showed significant retinal microvascular abnormalities, including wider arterioles and venules, suggesting persistent endothelial dysfunction months after SARS-CoV-2 infection.’
#LongCOVID is #AirborneEndothelialShitshow so #WearN95
#LongCOVID is #AirborneEndothelialShitshow so #WearN95
June 8, 2026 at 5:03 PM
‘Children with post-COVID-19 syndrome (PCS) showed significant retinal microvascular abnormalities, including wider arterioles and venules, suggesting persistent endothelial dysfunction months after SARS-CoV-2 infection.’
#LongCOVID is #AirborneEndothelialShitshow so #WearN95
#LongCOVID is #AirborneEndothelialShitshow so #WearN95
My wax mortuary mannequin head made out of derma-surgery wax.
Real porcelain teeth, and acrylic green eyes with realistic venules.
#mortuary
#funeral
#mortuaryscience
#funeralscience
#art
#sculpture
Real porcelain teeth, and acrylic green eyes with realistic venules.
#mortuary
#funeral
#mortuaryscience
#funeralscience
#art
#sculpture
July 24, 2025 at 2:59 AM
My wax mortuary mannequin head made out of derma-surgery wax.
Real porcelain teeth, and acrylic green eyes with realistic venules.
#mortuary
#funeral
#mortuaryscience
#funeralscience
#art
#sculpture
Real porcelain teeth, and acrylic green eyes with realistic venules.
#mortuary
#funeral
#mortuaryscience
#funeralscience
#art
#sculpture
The gorgeous RAC (Regular Arrangement of Collecting venules) in the gastric body of normal mucosa.
Imaging done with the new #fujifilm 840TP therapeutic scope with EP-8000 processor. This is going to be a game changer in third space endoscopy
#royalperthhospital
#esd
#poem
#endoscopy
Imaging done with the new #fujifilm 840TP therapeutic scope with EP-8000 processor. This is going to be a game changer in third space endoscopy
#royalperthhospital
#esd
#poem
#endoscopy
December 3, 2024 at 1:16 AM
The gorgeous RAC (Regular Arrangement of Collecting venules) in the gastric body of normal mucosa.
Imaging done with the new #fujifilm 840TP therapeutic scope with EP-8000 processor. This is going to be a game changer in third space endoscopy
#royalperthhospital
#esd
#poem
#endoscopy
Imaging done with the new #fujifilm 840TP therapeutic scope with EP-8000 processor. This is going to be a game changer in third space endoscopy
#royalperthhospital
#esd
#poem
#endoscopy
After presenting my poster at #INCI25 about the potential of CD40 agonist to enhance anti tumor immunity of tumor-derived cDCs, the session started with an excellent talk by Gabriele Bergers about the key role of the diva’s of endothelial cells, the high endothelial venules in anti-tumor immunity!
May 8, 2025 at 1:16 PM
After presenting my poster at #INCI25 about the potential of CD40 agonist to enhance anti tumor immunity of tumor-derived cDCs, the session started with an excellent talk by Gabriele Bergers about the key role of the diva’s of endothelial cells, the high endothelial venules in anti-tumor immunity!
In @cp-cellrepmed.bsky.social, IPBS researchers propose a treatment based on optimized antibodies that, in mice, increases the proportion of HEV blood vessels and facilitates killer cell entry into tumors.
These molecules are currently in clinical trials ⤵️
buff.ly/Ip3US2l
These molecules are currently in clinical trials ⤵️
buff.ly/Ip3US2l
June 3, 2025 at 1:24 PM
In @cp-cellrepmed.bsky.social, IPBS researchers propose a treatment based on optimized antibodies that, in mice, increases the proportion of HEV blood vessels and facilitates killer cell entry into tumors.
These molecules are currently in clinical trials ⤵️
buff.ly/Ip3US2l
These molecules are currently in clinical trials ⤵️
buff.ly/Ip3US2l