#xenium
April 18, 2025 at 1:17 PM
Mouse lung infected with Mycobacterium #tuberculosis; #xenium #immunology #Bcells and some other stuff 😂 @tiphainecms.bsky.social
November 15, 2024 at 4:47 PM
🧬If you work with @10xgenomics.bsky.social Xenium, this might be of your interest.

Our new study on Xenium exploration best practice and comparing it with other commercial platforms is now out in @naturemethods.bsky.social

www.nature.com/articles/s41...
Optimizing Xenium In Situ data utility by quality assessment and best-practice analysis workflows - Nature Methods
This study presents a comprehensive evaluation of Xenium In Situ datasets and provides recommendations on analysis workflows.
www.nature.com
March 14, 2025 at 2:38 PM
Oldskool GFX entry for this year's Xenium! Featuring some art based on Voyage of BSM Pandora.
August 28, 2026 at 8:28 PM
Xenium product updates : RNA and protein multiomics workflow @10xgenomics.bsky.social #AGBT2025 #AGBT25
February 23, 2025 at 8:24 PM
Comparing Imaging-based #SpatialTranscriptimics methods

CosMx vs MERFISH vs Xenium
1k vs 500 vs 339 plex

FFPE👤Lung/Mesothelium Tumor Microarray

CosMX▶️highest transcript counts/cell
Xenium▶️lowest FDR & highest cell segmentation precision

bioRxiv 2024
www.biorxiv.org/content/10.1...
December 19, 2024 at 12:21 PM
Eavesdropping on Notch-Delta chatter at endothelia-fibroblast niche #HCC #Xenium
November 18, 2024 at 5:58 AM
First 10X Xenium run is underway! Only 61 hours to go.
November 15, 2024 at 8:53 PM
Brand new 10X Xenium data from the mouse brain for #FluorescenceFriday! This image was made possible by fantastic MD/PhD student Olivia Drake and a collaboration with Jasper Heinsbroek's lab.

🟢 Drd1
🔴 Drd2
November 22, 2024 at 1:36 PM
#FluorescenceFriday Some favorite transcriptionally-defined spatial domains identified using the 10X Genomics Xenium platform in the mouse brain.
April 25, 2025 at 1:53 PM
The seminar I've done for #Xenium #demoparty Is up on youtube for your viewing pleasure! If you want to know more about #TIC-80 coding check out: www.youtube.com/watch?v=KPRH...
Xenium 2025 Seminar - Tricks for TIC-80 – how to get the most out of the fantasy console
YouTube video by MrSuule
www.youtube.com
September 14, 2025 at 10:36 PM
Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling
Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling
Computational assessment identifies probe binding errors in a widely used commercial platform for spatial transcriptomics.
buff.ly
May 24, 2026 at 8:21 AM
Ongoing installation…..#xenium @10xgenomics.bsky.social
November 25, 2024 at 10:34 AM
November 15, 2024 at 8:24 AM
1/ Excited to share our new bioRxiv preprint!
"4D spatial transcriptomics reveals nodule identity emerges through stacked parallel developmental programs"
📄 doi.org/10.64898/202... Using Xenium, we generated a 4D (3D space + time) atlas of nodule development in Medicago truncatula.
June 24, 2026 at 10:52 PM
Optimizing Xenium In Situ data utility by quality assessment and best-practice analysis workflows www.nature.com/articles/s4... #spatialtranscriptome
March 15, 2025 at 2:15 PM
#FluorescenceFriday Location of different classes of GABAergic interneurons derived from the medial ganglionic eminence in the mouse brain. Identified using the 10X Xenium platform, with @odrake.bsky.social and Jasper Heinsbroek.
September 18, 2026 at 10:15 PM
🌱 Xenium breaks barriers in plant spatial biology!

Thick cell walls, autofluorescence & complex tissues have long challenged spatial transcriptomics. A new bioRxiv preprint shows an optimised @10xgenomics.bsky.social Xenium workflow for Medicago truncatula roots & nodules.

#PlantScience #Xenium
August 14, 2025 at 2:17 AM
Kudos to the Xenium Explorer team at 10x Genomics for consistently upleveling what's possible out of the box for Xenium analysis!

Check out our analysis page to see all Xenium analysis improvements! bit.ly/4flCNSu

#spatialbiology #insitu #singlecellspatial #bioinformatics
December 13, 2024 at 6:24 PM
Altera (Xenium Whole Transcriptome) is coming👹

On #DuctalCarcinomaInSitu DCIS

vs Xenium 280 Xenium 5K
Resolving most myeloid states

Inferring #CopyNumberVariation➡️
Spatial clonal tracing
Any clone-specific immune/vascular niches?😆

bioRxiv 2026
www.biorxiv.org/content/10.6...
August 26, 2026 at 5:56 PM
A study from @sergiomarcosalas.bsky.social @nilssonlab.org and colleagues presents a comprehensive evaluation of Xenium in situ datasets and provides recommendations on analysis workflows. @scilifelab.se

www.nature.com/articles/s41...
March 13, 2025 at 6:54 PM
New @maxplanck.de study: We looked for left-right differences of gene expression and cell-type abundances in the brains of MICE 🐭using Xenium @10xgenomics.bsky.social. Possible clues to how functional brain asymmetry is supported !! www.biorxiv.org/content/10.1... Short thread below ⬇️
September 12, 2025 at 7:10 AM
Super excited about this ongoing spatial transcriptomics study in locus coeruleus of human 🧠. Expression of norepinephrine neurons - TH🔴, DBH🟢 and SLC6A2🟡 overlaid on post-Xenium H&E stain, allowing correlation of neuromelanin content (brown pigment) w/ gene expression #FluorescenceFriday 🔬🧪
October 10, 2025 at 3:33 PM
Siempre me gustaron las demos de Amiga, donde talentosos programadores y diseñadores exprimen el hardware. Y esta, llamada "Spooky Town", tiene dos escenas en concreto que son una pasada 💀
#amiga #retrogaming #demo
Spooky Town by Ghostown - 1st place in Amiga Demo Compo at Xenium 2026 (Amiga Demoscene)
YouTube video by Demoscene PL
www.youtube.com
October 6, 2026 at 7:55 PM
#SpatialTranscriptomics

Optimizing Xenium In Situ data utility by quality assessment & best-practice analysis workflows

Must-read for Xenium user🔥

👉Segmentation
👉Spatially variable feature selection
👉Imputation
👉Spatial domain identification

#NatMethods 2025
www.nature.com/articles/s41...
March 7, 2026 at 1:41 PM