Carmelo Ferrai
@carmeloferrai.bsky.social
RNAPII &Transcription Regulation -Chromatin Conformation & Nuclear Architecture - ESCs & Neuronal Differentiation - Nuclear Mechanotransduction - Cell Plasticity
UMG, Göttingen, Germany
UMG, Göttingen, Germany
Pinned
Carmelo Ferrai
@carmeloferrai.bsky.social
· Feb 14
Tread -1- EpiSci - I am very proud to share with you our new study that you can access on @biorxivpreprint.bsky.social (see link below)
"The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A.
www.biorxiv.org/content/10.6...
"The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A.
www.biorxiv.org/content/10.6...
Reposted by Carmelo Ferrai
The final version is now online! #RNALocalization #Chromatin #FunctionalGenomics #CellMigration #CancerBiology www.nature.com/articles/s41...
August 11, 2026 at 9:13 PM
The final version is now online! #RNALocalization #Chromatin #FunctionalGenomics #CellMigration #CancerBiology www.nature.com/articles/s41...
Prof. Jacopo Meldolesi passed away. He was a great teacher and a lovely person with an extraordinary passion for neuroscience to which he tirelessy dedicated his life. Farewell Jacopo it was a privilege knowing you and sharing with you a few steps on the journey of scientific discovery.
RIP Jacopo
RIP Jacopo
August 26, 2026 at 5:48 AM
Prof. Jacopo Meldolesi passed away. He was a great teacher and a lovely person with an extraordinary passion for neuroscience to which he tirelessy dedicated his life. Farewell Jacopo it was a privilege knowing you and sharing with you a few steps on the journey of scientific discovery.
RIP Jacopo
RIP Jacopo
Reposted by Carmelo Ferrai
Are you in Freiburg and interested in biophysics? Remember to sign up for the Biophysical Coffee ☕ Meeting Freiburg, only a few days are left! Talks and Posters will be selected from registered participants.
Participation is free, but registration is required.
www.ie-freiburg.mpg.de/events/41674...
Participation is free, but registration is required.
www.ie-freiburg.mpg.de/events/41674...
June 11, 2025 at 1:03 PM
Are you in Freiburg and interested in biophysics? Remember to sign up for the Biophysical Coffee ☕ Meeting Freiburg, only a few days are left! Talks and Posters will be selected from registered participants.
Participation is free, but registration is required.
www.ie-freiburg.mpg.de/events/41674...
Participation is free, but registration is required.
www.ie-freiburg.mpg.de/events/41674...
Reposted by Carmelo Ferrai
Dear Freiburg Biophysics community,
We are happy to announce the 2026 Biophysical Coffee Meeting Freiburg on October 02, 2026!
There will be talks, posters, and plenty of time for discussion and to exchange ideas.
Please sign up here: register.ie-freiburg.mpg.de/event/26
We are happy to announce the 2026 Biophysical Coffee Meeting Freiburg on October 02, 2026!
There will be talks, posters, and plenty of time for discussion and to exchange ideas.
Please sign up here: register.ie-freiburg.mpg.de/event/26
August 24, 2026 at 7:34 PM
Dear Freiburg Biophysics community,
We are happy to announce the 2026 Biophysical Coffee Meeting Freiburg on October 02, 2026!
There will be talks, posters, and plenty of time for discussion and to exchange ideas.
Please sign up here: register.ie-freiburg.mpg.de/event/26
We are happy to announce the 2026 Biophysical Coffee Meeting Freiburg on October 02, 2026!
There will be talks, posters, and plenty of time for discussion and to exchange ideas.
Please sign up here: register.ie-freiburg.mpg.de/event/26
Reposted by Carmelo Ferrai
If you or someone you know is interested in joining a fun and productive lab (JP Armache laboratory at Penn State University) to work on exciting projects, please follow or share the link below.
psu.wd1.myworkdayjobs.com/PSU_Academic...
psu.wd1.myworkdayjobs.com/PSU_Academic...
Postdoctoral Position
APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...
psu.wd1.myworkdayjobs.com
July 8, 2026 at 8:53 PM
If you or someone you know is interested in joining a fun and productive lab (JP Armache laboratory at Penn State University) to work on exciting projects, please follow or share the link below.
psu.wd1.myworkdayjobs.com/PSU_Academic...
psu.wd1.myworkdayjobs.com/PSU_Academic...
Reposted by Carmelo Ferrai
Don't miss your chance to register and send your abstract!
🚨Transcription and Chromatin UK is back for 2025🚨
We're in Manchester, UK 17th-19th September for the 3rd annual transcription and chromatin conference. Abstract deadline is the 17th July so make sure you register!
www.eventsforce.net/biochemsoc/f...
We're in Manchester, UK 17th-19th September for the 3rd annual transcription and chromatin conference. Abstract deadline is the 17th July so make sure you register!
www.eventsforce.net/biochemsoc/f...
www.eventsforce.net
July 16, 2025 at 4:12 PM
Don't miss your chance to register and send your abstract!
Reposted by Carmelo Ferrai
🧬 𝐓𝐫𝐚𝐧𝐬𝐜𝐫𝐢𝐩𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐂𝐡𝐫𝐨𝐦𝐚𝐭𝐢𝐧 𝐔𝐊 𝟐𝟎𝟐𝟔 🧬
Join us in York 18–20 November! We have an exciting program, presentation opportunities available and super-early booking discounts if you register by 18th August! More information here: www.eventsforce.net/biochemsoc/f...
Join us in York 18–20 November! We have an exciting program, presentation opportunities available and super-early booking discounts if you register by 18th August! More information here: www.eventsforce.net/biochemsoc/f...
www.eventsforce.net
August 11, 2026 at 10:53 AM
🧬 𝐓𝐫𝐚𝐧𝐬𝐜𝐫𝐢𝐩𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐂𝐡𝐫𝐨𝐦𝐚𝐭𝐢𝐧 𝐔𝐊 𝟐𝟎𝟐𝟔 🧬
Join us in York 18–20 November! We have an exciting program, presentation opportunities available and super-early booking discounts if you register by 18th August! More information here: www.eventsforce.net/biochemsoc/f...
Join us in York 18–20 November! We have an exciting program, presentation opportunities available and super-early booking discounts if you register by 18th August! More information here: www.eventsforce.net/biochemsoc/f...
🤩
Talk by @carmeloferrai.bsky.social on: The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A
#sketchnote #science 🧪
bio-mat-sketches-mor.blogspot.com/2026/07/carm...
#sketchnote #science 🧪
bio-mat-sketches-mor.blogspot.com/2026/07/carm...
Carmelo Ferrai: The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A
A visual blog about science and tissue engineering. Based on live doodles/sketchnotes done during talks. Some with an abstract/writeup.
bio-mat-sketches-mor.blogspot.com
August 12, 2026 at 6:40 AM
🤩
Mega-enhancers compartmentalize transcriptionally active long genes in the brain
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Mega-enhancers compartmentalize transcriptionally active long genes in the brain - Nature Cell Biology
Zhao et al. describe an enhancer-dense nuclear microenvironment in the cerebellum that includes long neuronal genes and mega-enhancers. This microenvironment partly depends on the transcription factor...
www.nature.com
August 11, 2026 at 9:31 PM
Mega-enhancers compartmentalize transcriptionally active long genes in the brain
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Carmelo Ferrai
Last week I attended the 6th 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝗼𝗻 𝗠𝗲𝗰𝗵𝗮𝗻𝗼𝗯𝗶𝗼𝗹𝗼𝗴𝘆 #ISMB2026 that was organised as part of SynSci — Synergy for Science 2026 and did some #Sketchnotes along the way;
I plan to add the missing ones with time…
bio-mat-sketches-mor.blogspot.com/2026/07/2026...
I plan to add the missing ones with time…
bio-mat-sketches-mor.blogspot.com/2026/07/2026...
2026 International Society for Mechanobiology meeting in Glasgow at SynSci
A visual blog about science and tissue engineering. Based on live doodles/sketchnotes done during talks. Some with an abstract/writeup.
bio-mat-sketches-mor.blogspot.com
July 23, 2026 at 5:33 PM
Last week I attended the 6th 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝗼𝗻 𝗠𝗲𝗰𝗵𝗮𝗻𝗼𝗯𝗶𝗼𝗹𝗼𝗴𝘆 #ISMB2026 that was organised as part of SynSci — Synergy for Science 2026 and did some #Sketchnotes along the way;
I plan to add the missing ones with time…
bio-mat-sketches-mor.blogspot.com/2026/07/2026...
I plan to add the missing ones with time…
bio-mat-sketches-mor.blogspot.com/2026/07/2026...
Reposted by Carmelo Ferrai
Chonkit Lio, Yuexia Wang, Paige Wilson, Howard Worman, Wakam Chang, Gregg Gundersen & team find that farnesylated prelamin A variants associated with premature aging disorders disrupt mobility of LINC complex proteins leading to defects in polarity.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
July 13, 2026 at 11:14 AM
Chonkit Lio, Yuexia Wang, Paige Wilson, Howard Worman, Wakam Chang, Gregg Gundersen & team find that farnesylated prelamin A variants associated with premature aging disorders disrupt mobility of LINC complex proteins leading to defects in polarity.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
@xaviertrepat.bsky.social rocking the stage here at the SynSci — Synergy for Science 2026 awesome mechano-biology data in defining cell patterning
July 13, 2026 at 1:11 PM
@xaviertrepat.bsky.social rocking the stage here at the SynSci — Synergy for Science 2026 awesome mechano-biology data in defining cell patterning
Reposted by Carmelo Ferrai
My lab is hiring! We have an open postdoc position to study the endometrial-embryo interface using organoids, embryo models, and live imaging. Reach out or apply: bit.ly/4duGA0P
Postdoctoral Research Fellow (Warmflash) Stem Cell Biology
We are seeking a postdoctoral researcher to join an interdisciplinary project focused on the biology of embryo implantation. The position centers on understanding how the endometrium and early embryo ...
bit.ly
May 18, 2026 at 3:12 PM
My lab is hiring! We have an open postdoc position to study the endometrial-embryo interface using organoids, embryo models, and live imaging. Reach out or apply: bit.ly/4duGA0P
Reposted by Carmelo Ferrai
Multi-ciliated cells drive many key events, including, for example, expelling pathogens and debris from our lung airways. @raghavan-thiaga.bsky.social Provides a great introduction to the cell biology behind this, and the many unanswered questions. Plus lovely images!! Check it out. 🧪
From single-celled organisms to ciliated epithelia in metazoans, precise positioning of basal bodies (BBs), which anchor motile cilia, is essential for generating fluid flows.
Here, I, @raghavan-thiaga.bsky.social, will take you on a brief tour of how cells build this spatial organization.
Here, I, @raghavan-thiaga.bsky.social, will take you on a brief tour of how cells build this spatial organization.
July 5, 2026 at 9:12 AM
Multi-ciliated cells drive many key events, including, for example, expelling pathogens and debris from our lung airways. @raghavan-thiaga.bsky.social Provides a great introduction to the cell biology behind this, and the many unanswered questions. Plus lovely images!! Check it out. 🧪
Reposted by Carmelo Ferrai
Paying peer reviewers
Interview with @danielgorelick.bsky.social about @biologyopen.bsky.social Fast & Fair trial in which peer reviewers were paid £220/review
Spoiler: it works - fast, high quality reviews
www.nature.com/articles/d41...
Interview with @danielgorelick.bsky.social about @biologyopen.bsky.social Fast & Fair trial in which peer reviewers were paid £220/review
Spoiler: it works - fast, high quality reviews
www.nature.com/articles/d41...
Why paying peer reviewers works, according to a journal’s editor-in-chief
A biology journal that paid peer reviewers found that the approach cut the time to a first editorial decision by 85% and maintained high-quality reviews.
www.nature.com
July 2, 2026 at 5:36 AM
Paying peer reviewers
Interview with @danielgorelick.bsky.social about @biologyopen.bsky.social Fast & Fair trial in which peer reviewers were paid £220/review
Spoiler: it works - fast, high quality reviews
www.nature.com/articles/d41...
Interview with @danielgorelick.bsky.social about @biologyopen.bsky.social Fast & Fair trial in which peer reviewers were paid £220/review
Spoiler: it works - fast, high quality reviews
www.nature.com/articles/d41...
Reposted by Carmelo Ferrai
The Kaplan Lab at the University of Pittsburgh has received funds to recruit a postdoctoral fellow to establish a multiplexed assay of variant effect for a disease gene. This relates to our studies on RNA Polymerase II. This project requires experience with human cell lines and genomics 1/
Post Doctoral Associate
Click the link provided to see the complete job description.
cfopitt.taleo.net
June 29, 2026 at 5:19 PM
The Kaplan Lab at the University of Pittsburgh has received funds to recruit a postdoctoral fellow to establish a multiplexed assay of variant effect for a disease gene. This relates to our studies on RNA Polymerase II. This project requires experience with human cell lines and genomics 1/
Reposted by Carmelo Ferrai
I have spent a long time resisting the use of AI in my everyday task, let alone in the process of scientific production (text, figures, ideas) which is anyway the bit of this weird profession that I enjoy the most. In the ensuing mini-rant, echoing Aydan’s thoughts, I want to highlight few things…
I have been thinking since yesterday about why I find the 1% thing so, so disturbing. It's a visceral reaction of 'just no', which goes beyond the general yuck towards the enshittification of/via AI. I have finally put my finger on it: it is the feeling you get when
June 27, 2026 at 12:15 PM
I have spent a long time resisting the use of AI in my everyday task, let alone in the process of scientific production (text, figures, ideas) which is anyway the bit of this weird profession that I enjoy the most. In the ensuing mini-rant, echoing Aydan’s thoughts, I want to highlight few things…
Reposted by Carmelo Ferrai
1/9 A few thoughts and personal opinions on the use of AI in research evaluation. I suspect many of these changes may be inevitable, so the real question may not be whether this will happen, but how we shape it responsibly 🧵
June 28, 2026 at 11:45 AM
1/9 A few thoughts and personal opinions on the use of AI in research evaluation. I suspect many of these changes may be inevitable, so the real question may not be whether this will happen, but how we shape it responsibly 🧵
RIP Frank Grosveld
RIP Frank Grosveld. Gene regulation researcher at its best.
June 29, 2026 at 5:09 AM
RIP Frank Grosveld
How does the plasma #membrane preserve its #lipid identity under stress? The Baskin and Balla labs report a homeostatic circuit linking PI4P, phosphatidylserine, RhoB, and phospholipase D-driven phosphatidic acid. hubs.la/Q04mQjrC0
June 28, 2026 at 8:42 AM
How does the plasma #membrane preserve its #lipid identity under stress? The Baskin and Balla labs report a homeostatic circuit linking PI4P, phosphatidylserine, RhoB, and phospholipase D-driven phosphatidic acid. hubs.la/Q04mQjrC0
Very nice!
@mornorse.bsky.social bio-mat-sketches-mor.blogspot.com/2024/11/cars...
@carstenschulte4.bsky.social
@mornorse.bsky.social bio-mat-sketches-mor.blogspot.com/2024/11/cars...
@carstenschulte4.bsky.social
Carsten Schulte: Cellular Mechanobiology in Health & Disease: A Tour de Force
A visual blog about science and tissue engineering. Based on live doodles/sketchnotes done during talks. Some with an abstract/writeup.
bio-mat-sketches-mor.blogspot.com
June 28, 2026 at 6:50 AM
Reposted by Carmelo Ferrai
Hi - I draw along talks for a hobby - making #sketchnotes, mainly #science, sometimes #politics that I publish on my blog:
bio-mat-sketches-mor.blogspot.com
bio-mat-sketches-mor.blogspot.com
TalksAsDoodles
A visual blog about science and tissue engineering. Based on live doodles/sketchnotes done during talks. Some with an abstract/writeup.
bio-mat-sketches-mor.blogspot.com
March 21, 2025 at 12:46 PM
Hi - I draw along talks for a hobby - making #sketchnotes, mainly #science, sometimes #politics that I publish on my blog:
bio-mat-sketches-mor.blogspot.com
bio-mat-sketches-mor.blogspot.com
Reposted by Carmelo Ferrai
Our Special Issue: Cell Biology of the Nucleus has been building over the last few months. In the coming weeks, we’ll be highlighting all the articles in this issue.
First up, we have an interview with our Guest Editor @abbybuch.bsky.social: journals.biologists.com/jcs/article/...
#CellBio #nucleus
First up, we have an interview with our Guest Editor @abbybuch.bsky.social: journals.biologists.com/jcs/article/...
#CellBio #nucleus
June 25, 2026 at 1:21 PM
Our Special Issue: Cell Biology of the Nucleus has been building over the last few months. In the coming weeks, we’ll be highlighting all the articles in this issue.
First up, we have an interview with our Guest Editor @abbybuch.bsky.social: journals.biologists.com/jcs/article/...
#CellBio #nucleus
First up, we have an interview with our Guest Editor @abbybuch.bsky.social: journals.biologists.com/jcs/article/...
#CellBio #nucleus