Frank Conlon
@fconlon.bsky.social
Exploring heart development using proteomics and genetics to investigate sex differences. Passionate fly tyer and fly fisher.
Reposted by Frank Conlon
RESEARCH PAPER: DDX3X-mediated translation of structured cardiac mRNAs is essential for female heart development
By Mason et al. and Frank Conlon
➡️ https://genesdev.cshlp.org/content/40/13-14/1029.abstract
#cardiacdevelopment #sexdifferences #Xlinked #translation
By Mason et al. and Frank Conlon
➡️ https://genesdev.cshlp.org/content/40/13-14/1029.abstract
#cardiacdevelopment #sexdifferences #Xlinked #translation
July 7, 2026 at 6:00 PM
RESEARCH PAPER: DDX3X-mediated translation of structured cardiac mRNAs is essential for female heart development
By Mason et al. and Frank Conlon
➡️ https://genesdev.cshlp.org/content/40/13-14/1029.abstract
#cardiacdevelopment #sexdifferences #Xlinked #translation
By Mason et al. and Frank Conlon
➡️ https://genesdev.cshlp.org/content/40/13-14/1029.abstract
#cardiacdevelopment #sexdifferences #Xlinked #translation
Congrats to my PhD student Kayla Mason!!
Scientists discover a genetic mechanism that protects the developing female heart.
news.unchealthcare.org/2026/07/gene...
Scientific article: genesdev.cshlp.org/content/40/1...
#DDX3X #RNA #HeartDevelopment #CongenitalHeartDisease
Scientists discover a genetic mechanism that protects the developing female heart.
news.unchealthcare.org/2026/07/gene...
Scientific article: genesdev.cshlp.org/content/40/1...
#DDX3X #RNA #HeartDevelopment #CongenitalHeartDisease
July 22, 2026 at 6:22 PM
Congrats to my PhD student Kayla Mason!!
Scientists discover a genetic mechanism that protects the developing female heart.
news.unchealthcare.org/2026/07/gene...
Scientific article: genesdev.cshlp.org/content/40/1...
#DDX3X #RNA #HeartDevelopment #CongenitalHeartDisease
Scientists discover a genetic mechanism that protects the developing female heart.
news.unchealthcare.org/2026/07/gene...
Scientific article: genesdev.cshlp.org/content/40/1...
#DDX3X #RNA #HeartDevelopment #CongenitalHeartDisease
Reposted by Frank Conlon
Congrats to some old friends and amazing scientific colleagues on their election to the National Academy of Sciences
www.nasonline.org/news/2025-na...
www.nasonline.org/news/2025-na...
April 29, 2025 at 7:16 PM
Congrats to some old friends and amazing scientific colleagues on their election to the National Academy of Sciences
www.nasonline.org/news/2025-na...
www.nasonline.org/news/2025-na...
A huge THANK YOU to Robin Lovell-Badge for teaching my class, Sex Differences in Human Disease about the discovery of SRY and the ethics of organoids. they were spellbound..
February 14, 2025 at 1:40 PM
A huge THANK YOU to Robin Lovell-Badge for teaching my class, Sex Differences in Human Disease about the discovery of SRY and the ethics of organoids. they were spellbound..
Congratulations to my PhD student Ike Emerson for showing sex differences in the heart are regulated through X-linked miRNAs and a big thank you to Bill Marzluff!
www.ahajournals.org/doi/full/10....
www.ahajournals.org/doi/full/10....
X-Chromosome–Linked miRNAs Regulate Sex Differences in Cardiac Physiology | Circulation Research
BACKGROUND: Males and females exhibit distinct anatomic and functional characteristics of the
heart, predisposing them to specific disease states. METHODS: We identified microRNAs (miRNAs/miR) with ...
www.ahajournals.org
January 30, 2025 at 9:17 PM
Congratulations to my PhD student Ike Emerson for showing sex differences in the heart are regulated through X-linked miRNAs and a big thank you to Bill Marzluff!
www.ahajournals.org/doi/full/10....
www.ahajournals.org/doi/full/10....
Crowd Sourcing: Does anyone know an AI platform, preferaably free for a trial, that can generate schematic scientific models or diagrams?
December 29, 2024 at 1:59 PM
Crowd Sourcing: Does anyone know an AI platform, preferaably free for a trial, that can generate schematic scientific models or diagrams?
The AI review of grant applications is incredibly realistic! Each time I put word-for-word the same grant in AI, I get completely differrnt scores and critiques.
December 23, 2024 at 5:09 PM
The AI review of grant applications is incredibly realistic! Each time I put word-for-word the same grant in AI, I get completely differrnt scores and critiques.
Sunset in the 'backyard' last night.
November 25, 2024 at 12:49 PM
Sunset in the 'backyard' last night.
Reposted by Frank Conlon
A cardiac myocyte (heart muscle cell) going through cell division surrounded by cardiac myocytes not going through cell division. DNA (yellow), myosin II (cyan) and actin filaments (magenta) are shown. #FluorescenceFriday #Science #Biology #CellBiology #microscopy
November 22, 2024 at 3:16 PM
A cardiac myocyte (heart muscle cell) going through cell division surrounded by cardiac myocytes not going through cell division. DNA (yellow), myosin II (cyan) and actin filaments (magenta) are shown. #FluorescenceFriday #Science #Biology #CellBiology #microscopy
Reposted by Frank Conlon
The muscle of a heart photographed through an electron microscope. Pseudo-color shows the myosin II filaments that sit at the core of the #sarcomere (cyan), the borders of the sarcomere (purple), and #Mitochondria (pink)
#science #biology #cellbiology #microscopy #photography #cardiosky #medsky
#science #biology #cellbiology #microscopy #photography #cardiosky #medsky
November 18, 2024 at 4:48 PM
The muscle of a heart photographed through an electron microscope. Pseudo-color shows the myosin II filaments that sit at the core of the #sarcomere (cyan), the borders of the sarcomere (purple), and #Mitochondria (pink)
#science #biology #cellbiology #microscopy #photography #cardiosky #medsky
#science #biology #cellbiology #microscopy #photography #cardiosky #medsky
Reposted by Frank Conlon
Happy to be on Bluesky! Our lab is fascinated by how the brain develops, how this goes awry in disease, and this is co-opted in evolution. A major focus is dynamic spatial and temporal #RNA control in the developing brain.
Please see our new review on evolution!
www.sciencedirect.com/science/arti...
Please see our new review on evolution!
www.sciencedirect.com/science/arti...
How our brains are built: emerging approaches to understand human-specific features
Understanding what makes us uniquely human is a long-standing question permeating fields from genomics, neuroscience, and developmental biology to med…
www.sciencedirect.com
November 16, 2024 at 7:36 PM
Happy to be on Bluesky! Our lab is fascinated by how the brain develops, how this goes awry in disease, and this is co-opted in evolution. A major focus is dynamic spatial and temporal #RNA control in the developing brain.
Please see our new review on evolution!
www.sciencedirect.com/science/arti...
Please see our new review on evolution!
www.sciencedirect.com/science/arti...