Jitendra Gosai
@gosciee.bsky.social
Assistant Research Scientist @ ASU Biodesign Inst,
Molecular genetics, Molecular Microbiology, Computational Biology, Host microbe interactions, Biophysics
Father, Fixer, Photographer
Molecular genetics, Molecular Microbiology, Computational Biology, Host microbe interactions, Biophysics
Father, Fixer, Photographer
Reposted by Jitendra Gosai
Finally a more intuitaive way to learn pLDDT/pAE? 😎
sokrypton.github.io/protein_figh...
(Character idea from @hannes-stark.bsky.social & Alex Waldherr)
sokrypton.github.io/protein_figh...
(Character idea from @hannes-stark.bsky.social & Alex Waldherr)
September 14, 2026 at 1:47 PM
Finally a more intuitaive way to learn pLDDT/pAE? 😎
sokrypton.github.io/protein_figh...
(Character idea from @hannes-stark.bsky.social & Alex Waldherr)
sokrypton.github.io/protein_figh...
(Character idea from @hannes-stark.bsky.social & Alex Waldherr)
Reposted by Jitendra Gosai
Differences in Siderophore Production During the Growth of Phytoplankton in Southern Ocean Incubation Experiments Under High‐ and Low‐Iron Conditions enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/... #jcampubs 🌊
Differences in Siderophore Production During the Growth of Phytoplankton in Southern Ocean Incubation Experiments Under High‐ and Low‐Iron Conditions
Experiments performed in the Southern Ocean under low- and high-iron conditions showed that the heterotrophic bacteria community produced distinct iron-binding compounds called siderophores, dependin....
enviromicro-journals.onlinelibrary.wiley.com
September 4, 2026 at 4:46 PM
Differences in Siderophore Production During the Growth of Phytoplankton in Southern Ocean Incubation Experiments Under High‐ and Low‐Iron Conditions enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/... #jcampubs 🌊
Reposted by Jitendra Gosai
DeepKOALA: a scalable deep learning framework for KEGG Orthology assignment academic.oup.com/bib/article/... #jcampubs
DeepKOALA: a scalable deep learning framework for KEGG Orthology assignment
Abstract. The KEGG Orthology (KO) system links DNA and protein sequences to biological functions and pathways, providing a curated, fundamental, and consis
academic.oup.com
September 3, 2026 at 4:45 PM
DeepKOALA: a scalable deep learning framework for KEGG Orthology assignment academic.oup.com/bib/article/... #jcampubs
Placement of the results, figures and fig-legends in the manuscripts 50000 miles from one another has to go.
It is not 1990s anymore and this is plain dumb.
Review this for us but also open in three windows.
It is not 1990s anymore and this is plain dumb.
Review this for us but also open in three windows.
September 4, 2026 at 12:08 AM
Placement of the results, figures and fig-legends in the manuscripts 50000 miles from one another has to go.
It is not 1990s anymore and this is plain dumb.
Review this for us but also open in three windows.
It is not 1990s anymore and this is plain dumb.
Review this for us but also open in three windows.
Lots of TIL for me but 🤯
Avocado trees alternate their sex daily to ensure outcrossing. this rhythm is driven by the SDMYB transcription factor, a balanced polymorphism maintained by selection for >42 million years.
Avocado trees alternate their sex daily to ensure outcrossing. this rhythm is driven by the SDMYB transcription factor, a balanced polymorphism maintained by selection for >42 million years.
Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNAS
In avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm
of floral sex timing promotes cross-pollination between two ...
www.pnas.org
August 8, 2026 at 4:30 AM
Lots of TIL for me but 🤯
Avocado trees alternate their sex daily to ensure outcrossing. this rhythm is driven by the SDMYB transcription factor, a balanced polymorphism maintained by selection for >42 million years.
Avocado trees alternate their sex daily to ensure outcrossing. this rhythm is driven by the SDMYB transcription factor, a balanced polymorphism maintained by selection for >42 million years.
Capitalism can sometimes curb novelty and creativity. Esp. with AI, where the competition is intense, and even with swaths of capex, there is a need to streamline to survive, companies may have to make tough calls.
I hope this doesn’t mean a blow to one forefront of science to give way to another.
I hope this doesn’t mean a blow to one forefront of science to give way to another.
Google DeepMind dismantles Nobel-winning AlphaFold team in strategy shift
Landmark project that solved protein folding gives way to a wider race to build AI systems for scientific discovery
www.ft.com
July 29, 2026 at 4:22 PM
Capitalism can sometimes curb novelty and creativity. Esp. with AI, where the competition is intense, and even with swaths of capex, there is a need to streamline to survive, companies may have to make tough calls.
I hope this doesn’t mean a blow to one forefront of science to give way to another.
I hope this doesn’t mean a blow to one forefront of science to give way to another.
ngl thought this was a rangoli for a min
Amazing knots of words by Georg Bocskay, with pears and shell and a butterfly provided by Joris Hoefnagel, whose day is today.
July 25, 2026 at 12:22 AM
ngl thought this was a rangoli for a min
www.frontiersin.org/news/2026/07...
@frontiersin.bsky.social
Don’t miss the video.
YT top comment summarises better : Orcas prefer scrambled over sunny side up.
@frontiersin.bsky.social
Don’t miss the video.
YT top comment summarises better : Orcas prefer scrambled over sunny side up.
Orcas filmed ramming one of the world’s heaviest fish so hard it explodes, possibly for fun
Study documenting previously undescribed orca behavior in the Gulf of California finds hold-and-ram strategy could be parental investment – or entertainment
www.frontiersin.org
July 24, 2026 at 5:36 PM
www.frontiersin.org/news/2026/07...
@frontiersin.bsky.social
Don’t miss the video.
YT top comment summarises better : Orcas prefer scrambled over sunny side up.
@frontiersin.bsky.social
Don’t miss the video.
YT top comment summarises better : Orcas prefer scrambled over sunny side up.
A sentence with AI and employment in it is rarely an uplifting one these days.
Here’s the change.
America’s Enterprising Spirit Is Booming After Decades-Long Slump
www.nytimes.com/2026/07/17/b...
Here’s the change.
America’s Enterprising Spirit Is Booming After Decades-Long Slump
www.nytimes.com/2026/07/17/b...
America’s Enterprising Spirit Is Booming After Decades-Long Slump (Gift Article)
Hundreds of thousands of people are creating companies each year, ending a decades-long drought.
www.nytimes.com
July 17, 2026 at 4:13 PM
A sentence with AI and employment in it is rarely an uplifting one these days.
Here’s the change.
America’s Enterprising Spirit Is Booming After Decades-Long Slump
www.nytimes.com/2026/07/17/b...
Here’s the change.
America’s Enterprising Spirit Is Booming After Decades-Long Slump
www.nytimes.com/2026/07/17/b...
Go in for the bugs, stay for the commentary.
One of my favorite Ze Frank videos makes heavy use of Andreas' photography: www.youtube.com/watch?v=J4gJ...
True Facts: Leafhoppers and Friends
YouTube video by Ze Frank
www.youtube.com
July 10, 2026 at 4:18 PM
Go in for the bugs, stay for the commentary.
Reposted by Jitendra Gosai
New preprint! How do you engineer one of biology’s most complex enzymes without breaking it?
We used evolution as a guide to map a protein interface in nitrogenase, screening >9,000 variants to reveal sequence-function rules for future nitrogen fixation engineering.
www.biorxiv.org/content/10.6...
We used evolution as a guide to map a protein interface in nitrogenase, screening >9,000 variants to reveal sequence-function rules for future nitrogen fixation engineering.
www.biorxiv.org/content/10.6...
Evolution-guided engineering of an ancient nitrogenase interface enhances enzyme activity and stability
Nitrogenase is the only enzyme capable of biological nitrogen fixation and a major target for sustainable agricultural engineering, yet its functional and structural complexity has made it difficult t...
www.biorxiv.org
June 19, 2026 at 3:21 PM
New preprint! How do you engineer one of biology’s most complex enzymes without breaking it?
We used evolution as a guide to map a protein interface in nitrogenase, screening >9,000 variants to reveal sequence-function rules for future nitrogen fixation engineering.
www.biorxiv.org/content/10.6...
We used evolution as a guide to map a protein interface in nitrogenase, screening >9,000 variants to reveal sequence-function rules for future nitrogen fixation engineering.
www.biorxiv.org/content/10.6...
Reposted by Jitendra Gosai
How ancient are the building blocks of animal sensory systems?
Key components of animal sensory systems evolved before animals. We find that choanoflagellates possess diverse & spatially segregated TRP channels, pointing to ancient origins of sensory specialization.
doi.org/10.64898/202...
Key components of animal sensory systems evolved before animals. We find that choanoflagellates possess diverse & spatially segregated TRP channels, pointing to ancient origins of sensory specialization.
doi.org/10.64898/202...
June 16, 2026 at 8:28 AM
How ancient are the building blocks of animal sensory systems?
Key components of animal sensory systems evolved before animals. We find that choanoflagellates possess diverse & spatially segregated TRP channels, pointing to ancient origins of sensory specialization.
doi.org/10.64898/202...
Key components of animal sensory systems evolved before animals. We find that choanoflagellates possess diverse & spatially segregated TRP channels, pointing to ancient origins of sensory specialization.
doi.org/10.64898/202...
Reposted by Jitendra Gosai
A lot of work, over many years, and we finally see the missing piece at the heart of type 3 export!
Structure of the proton-powered secretion motor at the heart of the bacterial flagellum www.biorxiv.org/content/10.64898/2026.06.13.732081v1 #cryoem
June 16, 2026 at 4:53 PM
A lot of work, over many years, and we finally see the missing piece at the heart of type 3 export!
Reposted by Jitendra Gosai
The T6SS is a widespread nanoweapon deployed by #bacteria, but why is it deployed heterogeneously? @cascaleslab.bsky.social &co show that #Ecoli adopt distinct #T6SS attacker "ON" & defender "OFF" roles to optimize survival, a key strategy in microbial warfare @plosbiology.org 🧪 plos.io/3S5dL45
June 5, 2026 at 7:55 AM
The T6SS is a widespread nanoweapon deployed by #bacteria, but why is it deployed heterogeneously? @cascaleslab.bsky.social &co show that #Ecoli adopt distinct #T6SS attacker "ON" & defender "OFF" roles to optimize survival, a key strategy in microbial warfare @plosbiology.org 🧪 plos.io/3S5dL45
Reposted by Jitendra Gosai
If you are at the 2026 ASM Microbe meeting in Washington DC, please check out a talk on sensory origion of zorbs by our lab's postdoc Jitendra Gosai at the 'Holding Tight: the importance of bacterial adhesion' session on June 5th @gosciee.bsky.social
June 3, 2026 at 2:32 PM
If you are at the 2026 ASM Microbe meeting in Washington DC, please check out a talk on sensory origion of zorbs by our lab's postdoc Jitendra Gosai at the 'Holding Tight: the importance of bacterial adhesion' session on June 5th @gosciee.bsky.social
June 4, 2026 at 12:31 PM
Reposted by Jitendra Gosai
Bacterial transmembrane proteins usually localize inside the cell by "finding" a pre-localized protein, but how did the 1st protein get there? @vanipande.bsky.social found a protein in #B.subtilis that localizes by recognizing a *lipid* localization cue. #Microsky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
May 29, 2026 at 2:18 PM
Bacterial transmembrane proteins usually localize inside the cell by "finding" a pre-localized protein, but how did the 1st protein get there? @vanipande.bsky.social found a protein in #B.subtilis that localizes by recognizing a *lipid* localization cue. #Microsky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Jitendra Gosai
What is the scope of ISME Host Microbe, ISME's newest journal?
Effects of antimicrobial agents, human activities, immunity and environment on AND ecological studies, cross-kingdom studies, microbiome studies of host-microbiome/microbe interactions
academic.oup.com/ismehm/pages...
#MicrobialEcology
Effects of antimicrobial agents, human activities, immunity and environment on AND ecological studies, cross-kingdom studies, microbiome studies of host-microbiome/microbe interactions
academic.oup.com/ismehm/pages...
#MicrobialEcology
May 26, 2026 at 4:04 PM
What is the scope of ISME Host Microbe, ISME's newest journal?
Effects of antimicrobial agents, human activities, immunity and environment on AND ecological studies, cross-kingdom studies, microbiome studies of host-microbiome/microbe interactions
academic.oup.com/ismehm/pages...
#MicrobialEcology
Effects of antimicrobial agents, human activities, immunity and environment on AND ecological studies, cross-kingdom studies, microbiome studies of host-microbiome/microbe interactions
academic.oup.com/ismehm/pages...
#MicrobialEcology
Reposted by Jitendra Gosai
Microbial cross-feeding interactions reshape evolutionary trajectories of consumers by preserving motility. https://www.biorxiv.org/content/10.64898/2026.05.25.727712v1
May 26, 2026 at 3:17 AM
Microbial cross-feeding interactions reshape evolutionary trajectories of consumers by preserving motility. https://www.biorxiv.org/content/10.64898/2026.05.25.727712v1
More scientists as political leaders please!
Jasmine Clark will become the first Black woman with a science Ph.D. to serve in the U.S. House of Representatives. https://scim.ag/4dDZe6P
Microbiologist wins Georgia primary for U.S. House seat
Jasmine Clark is set to become the first Black congresswoman with a science Ph.D.
scim.ag
May 23, 2026 at 5:11 AM
More scientists as political leaders please!
What a waste of food and perfectly useful furniture.
Stephen Colbert and David Letterman throwing things off the Ed Sullivan Theater.
Colbert: “Anything you’d like to say, Dave?”
Letterman: “In the words of the great Edward R. Murrow to CBS: ‘Good night and good luck, motherfuckers.’”
Colbert: “Anything you’d like to say, Dave?”
Letterman: “In the words of the great Edward R. Murrow to CBS: ‘Good night and good luck, motherfuckers.’”
May 16, 2026 at 5:53 AM
What a waste of food and perfectly useful furniture.
Reposted by Jitendra Gosai
I went down the rabbit hole of finding more and found these peckers to be a fascinating species. The most mind-blowing part being:
February 27, 2026 at 5:07 PM
I went down the rabbit hole of finding more and found these peckers to be a fascinating species. The most mind-blowing part being:
Reposted by Jitendra Gosai
Delighted to see over 17 million new protein structure predictions from novel proteins in AllTheBacteria are now integrated into the AlphaFold Database at @ebi.embl.org !
Huge work from @gbouras13.bsky.social @oschwengers.bsky.social and friends to generate these.
www.ebi.ac.uk/about/news/u...
Huge work from @gbouras13.bsky.social @oschwengers.bsky.social and friends to generate these.
www.ebi.ac.uk/about/news/u...
AlphaFold Database welcomes community datasets
Latest AlphaFold Database update adds high-value datasets for microbial and viral proteins, generated by specialist communities
www.ebi.ac.uk
February 17, 2026 at 1:52 PM
Delighted to see over 17 million new protein structure predictions from novel proteins in AllTheBacteria are now integrated into the AlphaFold Database at @ebi.embl.org !
Huge work from @gbouras13.bsky.social @oschwengers.bsky.social and friends to generate these.
www.ebi.ac.uk/about/news/u...
Huge work from @gbouras13.bsky.social @oschwengers.bsky.social and friends to generate these.
www.ebi.ac.uk/about/news/u...
Me trying to reach "expansion" from "increase" via inflation, growth, enlargement and swelling.
Could i just have asked Gemini or GPT - yes, but, where is the gaudiloquence in that?
Could i just have asked Gemini or GPT - yes, but, where is the gaudiloquence in that?
February 18, 2026 at 5:25 AM
Me trying to reach "expansion" from "increase" via inflation, growth, enlargement and swelling.
Could i just have asked Gemini or GPT - yes, but, where is the gaudiloquence in that?
Could i just have asked Gemini or GPT - yes, but, where is the gaudiloquence in that?