José Delgado, Ph.D.
@jmdelgado.bsky.social
Studying mitochondrial responses to infection at UCLA | Mitochondriac | Autophagy| DEI | Outdoor enthusiast | he/él | 🇲🇽⛰🚴🏼🏳️🌈
https://josedelgadophd.wixsite.com/jose
https://josedelgadophd.wixsite.com/jose
Reposted by José Delgado, Ph.D.
BCB is recruiting a senior faculty member! We seek internationally recognized candidates at the Full Professor level with outstanding records of solving broad biological problems.
Learn more and apply here: apply.interfolio.com/192850
Learn more and apply here: apply.interfolio.com/192850
Apply - Interfolio
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apply.interfolio.com
September 14, 2026 at 3:16 PM
BCB is recruiting a senior faculty member! We seek internationally recognized candidates at the Full Professor level with outstanding records of solving broad biological problems.
Learn more and apply here: apply.interfolio.com/192850
Learn more and apply here: apply.interfolio.com/192850
August 21, 2026 at 7:40 PM
Reposted by José Delgado, Ph.D.
California Bill Would Create A $23 Billion Fund For University Research
California Bill Would Create A $23 Billion Fund For University Research
A California bill would give voters the chance to vote on whether the state should create a $23 billion bond that would be used to award grants to university researchers.
www.forbes.com
May 6, 2026 at 1:32 PM
California Bill Would Create A $23 Billion Fund For University Research
Check out the wonderful news piece by @vcallier.bsky.social on our SPOTs preprint!
Discovery bolsters theory that ancient mitochondria formed brand-new, specialized ‘sacs’ in cells by shedding their outer membranes
go.nature.com/49gTu1d
go.nature.com/49gTu1d
Mitochondria can spawn new ‘organelles’ — hinting at how modern cells evolved
Discovery bolsters theory that ancient mitochondria formed brand-new, specialized ‘sacs’ in cells by shedding their outer membranes.
go.nature.com
April 29, 2026 at 12:43 AM
Check out the wonderful news piece by @vcallier.bsky.social on our SPOTs preprint!
🚨New Pernas Lab Preprint is live!! 🚨
Here we show that mitochondria shed "new organelles" that engulf lysosomes and become acidified compartments during intracellular infection! Video below shows SPOTs acquiring a lyso (C: matrix, Y: OMM, R: Lyso) 🔬.
🔗: www.biorxiv.org/content/10.6...
Here we show that mitochondria shed "new organelles" that engulf lysosomes and become acidified compartments during intracellular infection! Video below shows SPOTs acquiring a lyso (C: matrix, Y: OMM, R: Lyso) 🔬.
🔗: www.biorxiv.org/content/10.6...
April 28, 2026 at 9:15 PM
🚨New Pernas Lab Preprint is live!! 🚨
Here we show that mitochondria shed "new organelles" that engulf lysosomes and become acidified compartments during intracellular infection! Video below shows SPOTs acquiring a lyso (C: matrix, Y: OMM, R: Lyso) 🔬.
🔗: www.biorxiv.org/content/10.6...
Here we show that mitochondria shed "new organelles" that engulf lysosomes and become acidified compartments during intracellular infection! Video below shows SPOTs acquiring a lyso (C: matrix, Y: OMM, R: Lyso) 🔬.
🔗: www.biorxiv.org/content/10.6...
Reposted by José Delgado, Ph.D.
Science is good. We should fund it.
April 11, 2026 at 12:14 AM
Science is good. We should fund it.
🚨UCLA and broader California science community
Join me in supporting SB 895: California Science & Health Research Bond Act
Sign ✍🏽: www.fundcascience.org
Email legislators!
Join me in supporting SB 895: California Science & Health Research Bond Act
Sign ✍🏽: www.fundcascience.org
Email legislators!
Fund CA Science
www.fundcascience.org
April 9, 2026 at 1:55 AM
🚨UCLA and broader California science community
Join me in supporting SB 895: California Science & Health Research Bond Act
Sign ✍🏽: www.fundcascience.org
Email legislators!
Join me in supporting SB 895: California Science & Health Research Bond Act
Sign ✍🏽: www.fundcascience.org
Email legislators!
Reposted by José Delgado, Ph.D.
Our paper is now out in Science! Super excited to share our discovery that #mitochondria #pearling is the elusive mechanism driving the regular distribution and inheritance of #mtDNA nucleoids 🧬 [1/6]
April 3, 2026 at 12:46 PM
Our paper is now out in Science! Super excited to share our discovery that #mitochondria #pearling is the elusive mechanism driving the regular distribution and inheritance of #mtDNA nucleoids 🧬 [1/6]
Reposted by José Delgado, Ph.D.
Gift link. NYT article about the fallout in one Harvard lab from the vandalism to the NIH.
www.nytimes.com/2026/03/13/u...
www.nytimes.com/2026/03/13/u...
His Harvard Lab Was Thriving. Then Came the Cuts.
www.nytimes.com
March 13, 2026 at 7:02 PM
Gift link. NYT article about the fallout in one Harvard lab from the vandalism to the NIH.
www.nytimes.com/2026/03/13/u...
www.nytimes.com/2026/03/13/u...
Reposted by José Delgado, Ph.D.
#NewResearch
The Toxoplasma gondii effector TgROP1 mimics host factors to bind VAPA/B, thereby establishing parasite–host ER contact sites.
#MicroSky 🦠
www.nature.com/articles/s41...
The Toxoplasma gondii effector TgROP1 mimics host factors to bind VAPA/B, thereby establishing parasite–host ER contact sites.
#MicroSky 🦠
www.nature.com/articles/s41...
Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection - Nature Microbiology
The Toxoplasma gondii effector TgROP1 mimics host factors to bind VAPA/B, thereby establishing parasite–host ER contact sites.
www.nature.com
November 26, 2025 at 3:51 PM
#NewResearch
The Toxoplasma gondii effector TgROP1 mimics host factors to bind VAPA/B, thereby establishing parasite–host ER contact sites.
#MicroSky 🦠
www.nature.com/articles/s41...
The Toxoplasma gondii effector TgROP1 mimics host factors to bind VAPA/B, thereby establishing parasite–host ER contact sites.
#MicroSky 🦠
www.nature.com/articles/s41...
🚨 New work out from the Pernas Lab. Congratulations to my labmate Chahat Mehra!!
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection
Nature Microbiology - The Toxoplasma gondii effector TgROP1 mimics host factors to bind VAPA/B, thereby establishing parasite–host ER contact sites.
rdcu.be
November 25, 2025 at 5:24 PM
🚨 New work out from the Pernas Lab. Congratulations to my labmate Chahat Mehra!!
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Reposted by José Delgado, Ph.D.
Applications are open for the Postdoctoral Enrichment Program (PDEP)—supporting postdocs as they advance cutting-edge research and build thriving scientific careers.
Learn more & apply: bwfund.org/pdep #bwfpdep
Learn more & apply: bwfund.org/pdep #bwfpdep
November 14, 2025 at 7:26 PM
Applications are open for the Postdoctoral Enrichment Program (PDEP)—supporting postdocs as they advance cutting-edge research and build thriving scientific careers.
Learn more & apply: bwfund.org/pdep #bwfpdep
Learn more & apply: bwfund.org/pdep #bwfpdep
Reposted by José Delgado, Ph.D.
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research
go.nature.com/4hriohE
go.nature.com/4hriohE
What makes PhD students happy? Good supervision
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research.
go.nature.com
October 22, 2025 at 9:53 AM
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research
go.nature.com/4hriohE
go.nature.com/4hriohE
Reposted by José Delgado, Ph.D.
Last year, we helped 100 students save $31K in grad school app fees, giving students from underserved communities the freedom to apply widely.
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
October 13, 2025 at 7:17 PM
Last year, we helped 100 students save $31K in grad school app fees, giving students from underserved communities the freedom to apply widely.
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
This year we lost 16 partners = $8.2K setback = 110 fewer dreams.
🎓 You can change that.
💸 Donate to open 110 new doors.
givebutter.com/supportCL
Reposted by José Delgado, Ph.D.
NEXT WEEK: Applying to grad programs in the sciences? 🧬✨
Hear directly from university administrators about the key do’s and don’ts for a standout application.
Join our Faculty Panel for practical advice & answers to your questions.
📅 10/7, 11am ET
📍 Register: www.eventbrite.com/e/faculty-pa...
Hear directly from university administrators about the key do’s and don’ts for a standout application.
Join our Faculty Panel for practical advice & answers to your questions.
📅 10/7, 11am ET
📍 Register: www.eventbrite.com/e/faculty-pa...
October 1, 2025 at 4:05 PM
NEXT WEEK: Applying to grad programs in the sciences? 🧬✨
Hear directly from university administrators about the key do’s and don’ts for a standout application.
Join our Faculty Panel for practical advice & answers to your questions.
📅 10/7, 11am ET
📍 Register: www.eventbrite.com/e/faculty-pa...
Hear directly from university administrators about the key do’s and don’ts for a standout application.
Join our Faculty Panel for practical advice & answers to your questions.
📅 10/7, 11am ET
📍 Register: www.eventbrite.com/e/faculty-pa...
Reposted by José Delgado, Ph.D.
Ribonucleotide incorporation into mitochondrial DNA drives inflammation
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
Ribonucleotide incorporation into mitochondrial DNA drives inflammation - Nature
Imbalanced nucleotide metabolism leads to age- and mtDNA-dependent inflammatory responses and senescence-associated secretory phenotype in senescence.
www.nature.com
September 24, 2025 at 4:31 PM
Ribonucleotide incorporation into mitochondrial DNA drives inflammation
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
Reposted by José Delgado, Ph.D.
Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti...
#Reproducibility
#Reproducibility
September 3, 2025 at 2:15 PM
Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti...
#Reproducibility
#Reproducibility
Reposted by José Delgado, Ph.D.
Join me in donating to ABRCMS. For many of us early in our careers (and for many of us now), this is THE conference. Let’s make sure future generations get the same experience.
I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾
I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾
Calling all @apsphysiology.bsky.social members: let’s help raise some money to support ABRCMS student presentation awards! Goal is $1200/discipline to support 12 awards by Sept 30th! 🧪 abrcms.org/donate/stude...
ABRCMS Fundraising - Student Presentation Awards - ABRCMS
Judges – Help Us Raise Funds for Student Presentation Awards Thank you for your service as a judge at ABRCMS. Your dedication has helped shape the future of countless student scientists, and we’re dee...
abrcms.org
August 21, 2025 at 2:48 AM
Join me in donating to ABRCMS. For many of us early in our careers (and for many of us now), this is THE conference. Let’s make sure future generations get the same experience.
I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾
I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾
Reposted by José Delgado, Ph.D.
Quite a week for #lipidtime: phenomenal study using bifunctional lipid probes to quantify intracellular lipid transport from @nadlerlab.bsky.social and colleagues is now out @nature.com! www.nature.com/articles/s41...
Quantitative imaging of lipid transport in mammalian cells - Nature
Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.
www.nature.com
August 20, 2025 at 10:01 PM
Quite a week for #lipidtime: phenomenal study using bifunctional lipid probes to quantify intracellular lipid transport from @nadlerlab.bsky.social and colleagues is now out @nature.com! www.nature.com/articles/s41...
Reposted by José Delgado, Ph.D.
📣 Are you a undergraduate student, graduate student, or early-career professional in the biomedical sciences looking to transition from academia into industry?
Join us for: Thriving in Biotech – Building Bridges, Breaking Barriers.
www.scientistsinsolidarity.org/conference
Join us for: Thriving in Biotech – Building Bridges, Breaking Barriers.
www.scientistsinsolidarity.org/conference
Conference — Scientists in Solidarity
www.scientistsinsolidarity.org
August 20, 2025 at 2:08 AM
📣 Are you a undergraduate student, graduate student, or early-career professional in the biomedical sciences looking to transition from academia into industry?
Join us for: Thriving in Biotech – Building Bridges, Breaking Barriers.
www.scientistsinsolidarity.org/conference
Join us for: Thriving in Biotech – Building Bridges, Breaking Barriers.
www.scientistsinsolidarity.org/conference
Reposted by José Delgado, Ph.D.
🎓 Planning to apply to STEM graduate programs?
Join us for our webinar: “Applying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET.
Gain key insights on:
✅ Grad school application timeline
✅ How to choose the right program
🔗 Register: eventbrite.com/e/gsmi-2025-...
Join us for our webinar: “Applying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET.
Gain key insights on:
✅ Grad school application timeline
✅ How to choose the right program
🔗 Register: eventbrite.com/e/gsmi-2025-...
August 17, 2025 at 9:43 PM
🎓 Planning to apply to STEM graduate programs?
Join us for our webinar: “Applying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET.
Gain key insights on:
✅ Grad school application timeline
✅ How to choose the right program
🔗 Register: eventbrite.com/e/gsmi-2025-...
Join us for our webinar: “Applying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET.
Gain key insights on:
✅ Grad school application timeline
✅ How to choose the right program
🔗 Register: eventbrite.com/e/gsmi-2025-...
New work out of the Pernas Lab!! Congratulations to my lab mates, especially Tania for spearheading this great story!! 🎉
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Mitochondria protect against an intracellular pathogen by restricting access to folate
As major consumers of cellular metabolites, mitochondria are poised to compete with invading microbes for the nutrients that they need to grow. Whether cells exploit mitochondrial metabolism to protec...
www.science.org
August 14, 2025 at 6:22 PM
New work out of the Pernas Lab!! Congratulations to my lab mates, especially Tania for spearheading this great story!! 🎉
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Great perspective piece out of my PhD lab! 👇🏽
The rapidly expanding role of LC3-interacting regions in #autophagy. New Perspective from Brian North, @doroteaartscience.bsky.social, Christopher Shoemaker and colleagues (Geisel School of Medicine, Dartmouth College): rupress.org/jcb/article/...
August 10, 2025 at 4:55 PM
Great perspective piece out of my PhD lab! 👇🏽
Reposted by José Delgado, Ph.D.
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...
August 6, 2025 at 3:36 PM
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...
Reposted by José Delgado, Ph.D.
A story from LAist (local LA public radio) about the freezing of funds. I have had my grant frozen, so has nearly everyone else i know. laist.com/news/climate...
UCLA tells researchers to 'immediately stop spending' after Trump administration freezes grant funds
The Trump administration cited alleged antisemitism at UCLA as a reason for suspending the funding. Years worth of research could be lost, one UCLA researcher said.
laist.com
August 2, 2025 at 9:58 PM
A story from LAist (local LA public radio) about the freezing of funds. I have had my grant frozen, so has nearly everyone else i know. laist.com/news/climate...