Disease Transcriptomics (NMorais) Lab
@nmoraislab.bsky.social
Disease Transcriptomics Lab, led by Nuno Barbosa-Morais, at the NOVA Medical School in Lisbon, Portugal.
https://diseasetranscriptomicslab.github.io/
https://diseasetranscriptomicslab.github.io/
New preprint 📣! We reanalysed stress granule transcriptomes and found differential centrifugation is strongly biased by RNA length. Correcting for this erases most reported overlap. Mitochondrial RNAs remain as a modest signal, hinting at immune signalling. doi.org/10.64898/202...
September 14, 2026 at 11:23 AM
New preprint 📣! We reanalysed stress granule transcriptomes and found differential centrifugation is strongly biased by RNA length. Correcting for this erases most reported overlap. Mitochondrial RNAs remain as a modest signal, hinting at immune signalling. doi.org/10.64898/202...
When the PI’s away, the Lab will happily and productively play. 🙂
August 14, 2026 at 11:03 AM
When the PI’s away, the Lab will happily and productively play. 🙂
Farewell and welcome: Marta Bica 🇵🇹(PhD alumna, 2018–2026) moves to Botton-Champalimaud Pancreatic Cancer Centre as a single-cell/spatial transcriptomics expert, while Alessandro Minguzzi 🇮🇹joins today, becoming a PhD student in Sept, studying CDKN2A in cancer. #Alumni #PhD
August 10, 2026 at 11:00 AM
Garbage In, Plot Out 🧠
A bioinformatics pipeline will always give you something: a plot, a p-value, a cluster. It won’t tell you whether the parameters you chose were the right ones. That’s the black box problem in bioinformatics 📊.
A thread on why critical thinking matters 🧵
A bioinformatics pipeline will always give you something: a plot, a p-value, a cluster. It won’t tell you whether the parameters you chose were the right ones. That’s the black box problem in bioinformatics 📊.
A thread on why critical thinking matters 🧵
August 7, 2026 at 11:01 AM
Garbage In, Plot Out 🧠
A bioinformatics pipeline will always give you something: a plot, a p-value, a cluster. It won’t tell you whether the parameters you chose were the right ones. That’s the black box problem in bioinformatics 📊.
A thread on why critical thinking matters 🧵
A bioinformatics pipeline will always give you something: a plot, a p-value, a cluster. It won’t tell you whether the parameters you chose were the right ones. That’s the black box problem in bioinformatics 📊.
A thread on why critical thinking matters 🧵
🚀 Our new research lab website is now live!
After a few months of moving, settling in, and rebuilding, the Disease Transcriptomics Lab is now online:
diseasetranscriptomicslab.github.io
Find out more about our research, tools, people, ethos, and opportunities to join us.
After a few months of moving, settling in, and rebuilding, the Disease Transcriptomics Lab is now online:
diseasetranscriptomicslab.github.io
Find out more about our research, tools, people, ethos, and opportunities to join us.
Disease Transcriptomics Lab · NMorais Lab
Decoding transcriptomes to understand disease. Computational biology research at NOVA Medical School, Lisbon.
diseasetranscriptomicslab.github.io
July 24, 2026 at 11:15 AM
🚀 Our new research lab website is now live!
After a few months of moving, settling in, and rebuilding, the Disease Transcriptomics Lab is now online:
diseasetranscriptomicslab.github.io
Find out more about our research, tools, people, ethos, and opportunities to join us.
After a few months of moving, settling in, and rebuilding, the Disease Transcriptomics Lab is now online:
diseasetranscriptomicslab.github.io
Find out more about our research, tools, people, ethos, and opportunities to join us.
Finally out, a much improved peer-reviewed article published in NAR Genomics & Bioinformatics @academic.oup.com.
👏 @ritamtbs.bsky.social and @a-kaizeler.bsky.social!
academic.oup.com/nargab/artic...
👏 @ritamtbs.bsky.social and @a-kaizeler.bsky.social!
academic.oup.com/nargab/artic...
June 8, 2026 at 9:54 PM
Finally out, a much improved peer-reviewed article published in NAR Genomics & Bioinformatics @academic.oup.com.
👏 @ritamtbs.bsky.social and @a-kaizeler.bsky.social!
academic.oup.com/nargab/artic...
👏 @ritamtbs.bsky.social and @a-kaizeler.bsky.social!
academic.oup.com/nargab/artic...
Reposted by Disease Transcriptomics (NMorais) Lab
🎥 NEW Getting to know BIOMICS Members episode!
Meet @mirimiam.bsky.social from @crg.eu, sharing his scientific journey, perspectives on collaboration, and research in evolutionary medical genomics.
📺 youtu.be/T5ZpgSiowY8
#BIOMICS #HorizonEurope #Genomics #BiomedicalScience
Meet @mirimiam.bsky.social from @crg.eu, sharing his scientific journey, perspectives on collaboration, and research in evolutionary medical genomics.
📺 youtu.be/T5ZpgSiowY8
#BIOMICS #HorizonEurope #Genomics #BiomedicalScience
BIOMICS Core Member: Manuel Irimia
YouTube video by BIOMICS Twinning
youtu.be
May 20, 2026 at 4:03 PM
🎥 NEW Getting to know BIOMICS Members episode!
Meet @mirimiam.bsky.social from @crg.eu, sharing his scientific journey, perspectives on collaboration, and research in evolutionary medical genomics.
📺 youtu.be/T5ZpgSiowY8
#BIOMICS #HorizonEurope #Genomics #BiomedicalScience
Meet @mirimiam.bsky.social from @crg.eu, sharing his scientific journey, perspectives on collaboration, and research in evolutionary medical genomics.
📺 youtu.be/T5ZpgSiowY8
#BIOMICS #HorizonEurope #Genomics #BiomedicalScience
Reposted by Disease Transcriptomics (NMorais) Lab
🚀 Today’s #BIOMICS course at @gimminstitute.bsky.social: A packed room exploring #probabilistic #model #building, #Bayesian thinking, #AI, diffusion models, and active learning 🧠📈
Fantastic discussions and engagement throughout the day!
#BIOMICS #AI #DataScience #MachineLearning #HorizonEurope
Fantastic discussions and engagement throughout the day!
#BIOMICS #AI #DataScience #MachineLearning #HorizonEurope
May 15, 2026 at 3:47 PM
🚀 Today’s #BIOMICS course at @gimminstitute.bsky.social: A packed room exploring #probabilistic #model #building, #Bayesian thinking, #AI, diffusion models, and active learning 🧠📈
Fantastic discussions and engagement throughout the day!
#BIOMICS #AI #DataScience #MachineLearning #HorizonEurope
Fantastic discussions and engagement throughout the day!
#BIOMICS #AI #DataScience #MachineLearning #HorizonEurope
Reposted by Disease Transcriptomics (NMorais) Lab
🚨 Now at @gimminstitute.bsky.social, Mafalda Dias & Jonathan Frazer, from @crg.eu talking about how we can read #evolutionary constraints with #deep #learning.
#EUfunded #BIOMICS #EvoMG
#EUfunded #BIOMICS #EvoMG
May 14, 2026 at 11:26 AM
🚨 Now at @gimminstitute.bsky.social, Mafalda Dias & Jonathan Frazer, from @crg.eu talking about how we can read #evolutionary constraints with #deep #learning.
#EUfunded #BIOMICS #EvoMG
#EUfunded #BIOMICS #EvoMG
Reposted by Disease Transcriptomics (NMorais) Lab
My Working Life article @science.org - When I stopped trying to have all the answers, my lab members thrived | Science | AAAS www.science.org/content/arti...
When I stopped trying to have all the answers, my lab members thrived
This professor learned “to be there when people struggled without taking the wheel,” he writes
www.science.org
May 14, 2026 at 6:28 PM
My Working Life article @science.org - When I stopped trying to have all the answers, my lab members thrived | Science | AAAS www.science.org/content/arti...
Reposted by Disease Transcriptomics (NMorais) Lab
Happening now 🚨
#BIOMICS Seminar by Manuel Irimia on “Evolutionary landscapes of zygotic genome activation across animals”
📍 In-person at GIMM Lisboa + live on Zoom
#BIOMICS #Seminar #Genomics #ZGA @mirimiam.bsky.social @nmoraislab.bsky.social
#BIOMICS Seminar by Manuel Irimia on “Evolutionary landscapes of zygotic genome activation across animals”
📍 In-person at GIMM Lisboa + live on Zoom
#BIOMICS #Seminar #Genomics #ZGA @mirimiam.bsky.social @nmoraislab.bsky.social
April 21, 2026 at 10:14 AM
Happening now 🚨
#BIOMICS Seminar by Manuel Irimia on “Evolutionary landscapes of zygotic genome activation across animals”
📍 In-person at GIMM Lisboa + live on Zoom
#BIOMICS #Seminar #Genomics #ZGA @mirimiam.bsky.social @nmoraislab.bsky.social
#BIOMICS Seminar by Manuel Irimia on “Evolutionary landscapes of zygotic genome activation across animals”
📍 In-person at GIMM Lisboa + live on Zoom
#BIOMICS #Seminar #Genomics #ZGA @mirimiam.bsky.social @nmoraislab.bsky.social
The Lab was well represented at the Bioinformatics Open Days @uminho.bsky.social (25-27 March), with Nuno giving a keynote lecture and @a-kaizeler.bsky.social, Francisca, and @ritamtbs.bsky.social presenting posters.
March 28, 2026 at 7:08 PM
The Lab was well represented at the Bioinformatics Open Days @uminho.bsky.social (25-27 March), with Nuno giving a keynote lecture and @a-kaizeler.bsky.social, Francisca, and @ritamtbs.bsky.social presenting posters.
Reposted by Disease Transcriptomics (NMorais) Lab
What comes after academia? 🤔
At our latest #BIOMICS workshop @GIMM, 17 participants explored career paths beyond the lab — working hands-on on CVs & LinkedIn profiles 💼
Thanks to our partners @crg.eu 🙌
🇪🇺 #HorizonEurope #FundedByEU #BeyondAcademia #PhDLife
At our latest #BIOMICS workshop @GIMM, 17 participants explored career paths beyond the lab — working hands-on on CVs & LinkedIn profiles 💼
Thanks to our partners @crg.eu 🙌
🇪🇺 #HorizonEurope #FundedByEU #BeyondAcademia #PhDLife
March 24, 2026 at 3:37 PM
What comes after academia? 🤔
At our latest #BIOMICS workshop @GIMM, 17 participants explored career paths beyond the lab — working hands-on on CVs & LinkedIn profiles 💼
Thanks to our partners @crg.eu 🙌
🇪🇺 #HorizonEurope #FundedByEU #BeyondAcademia #PhDLife
At our latest #BIOMICS workshop @GIMM, 17 participants explored career paths beyond the lab — working hands-on on CVs & LinkedIn profiles 💼
Thanks to our partners @crg.eu 🙌
🇪🇺 #HorizonEurope #FundedByEU #BeyondAcademia #PhDLife
We proudly have a new Master! 🥳
Our @djmarques.bsky.social stellarly defended his MSc dissertation, evaluated with a perfect 20/20! 🤓👏
Our @djmarques.bsky.social stellarly defended his MSc dissertation, evaluated with a perfect 20/20! 🤓👏
March 19, 2026 at 12:24 AM
We proudly have a new Master! 🥳
Our @djmarques.bsky.social stellarly defended his MSc dissertation, evaluated with a perfect 20/20! 🤓👏
Our @djmarques.bsky.social stellarly defended his MSc dissertation, evaluated with a perfect 20/20! 🤓👏
On the last 25th of February, Nuno introduced the Lab to our new colleagues in a seminar entitled "Thinking critically about big data at NOVA Medical School". It was very well attended (don't be fooled by the empty first couple of rows) and received. We feel very welcome at NMS! 😊
March 13, 2026 at 6:18 PM
On the last 25th of February, Nuno introduced the Lab to our new colleagues in a seminar entitled "Thinking critically about big data at NOVA Medical School". It was very well attended (don't be fooled by the empty first couple of rows) and received. We feel very welcome at NMS! 😊
Happy International Day of Women and Girls in Science! 👩🔬
February 11, 2026 at 11:09 PM
Happy International Day of Women and Girls in Science! 👩🔬
Nuno will, proudly and enthusiastically, repeat as one of the lecturers of the pioneering ISCTE EE Postgraduate Course in Critical Thinking for Decision Making (execed.iscte-iul.pt/en/applied-o...), brilliantly coordinated by José Maria Pimentel.
February 7, 2026 at 4:58 PM
Nuno will, proudly and enthusiastically, repeat as one of the lecturers of the pioneering ISCTE EE Postgraduate Course in Critical Thinking for Decision Making (execed.iscte-iul.pt/en/applied-o...), brilliantly coordinated by José Maria Pimentel.
On World Cancer Day, Francisca's PhD project was awarded an Oncology Research Grant by the Portuguese League Against Cancer (Southern Regional Center) and the Benfica Foundation, to support her work on testing predictive biomarkers of therapeutic response in rectal cancer. 🙏🦀⚕️💪
February 6, 2026 at 11:18 AM
On World Cancer Day, Francisca's PhD project was awarded an Oncology Research Grant by the Portuguese League Against Cancer (Southern Regional Center) and the Benfica Foundation, to support her work on testing predictive biomarkers of therapeutic response in rectal cancer. 🙏🦀⚕️💪
We are proud of the Lab's participation in the CAML & GIMM PhD Meeting this week: @a-kaizeler.bsky.social, @ritamtbs.bsky.social and Francisca eloquently presented their work to their colleagues 👏. @ritamtbs.bsky.social won the award for Best Poster Presentation by a 4th year PhD student! 🥇
January 30, 2026 at 5:16 PM
We are proud of the Lab's participation in the CAML & GIMM PhD Meeting this week: @a-kaizeler.bsky.social, @ritamtbs.bsky.social and Francisca eloquently presented their work to their colleagues 👏. @ritamtbs.bsky.social won the award for Best Poster Presentation by a 4th year PhD student! 🥇
Following the @bioconductor.bsky.social package, the @biorxivpreprint.bsky.social preprint: "Exploring molecular signatures of senescence with markeR, an R toolkit for evaluating gene sets as phenotypic markers". 💻🧬📰
👏 @ritamtbs.bsky.social 💪
www.biorxiv.org/content/10.6...
👏 @ritamtbs.bsky.social 💪
www.biorxiv.org/content/10.6...
December 11, 2025 at 10:49 AM
Following the @bioconductor.bsky.social package, the @biorxivpreprint.bsky.social preprint: "Exploring molecular signatures of senescence with markeR, an R toolkit for evaluating gene sets as phenotypic markers". 💻🧬📰
👏 @ritamtbs.bsky.social 💪
www.biorxiv.org/content/10.6...
👏 @ritamtbs.bsky.social 💪
www.biorxiv.org/content/10.6...
Reposted by Disease Transcriptomics (NMorais) Lab
⏰ Only 1 day left to apply!
Applications for the EvoMG-DN PhD positions close tomorrow.
If you plan to apply, this is your final chance.
Submit your application here → www.evomg-dn.eu
#PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA
Applications for the EvoMG-DN PhD positions close tomorrow.
If you plan to apply, this is your final chance.
Submit your application here → www.evomg-dn.eu
#PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA
November 29, 2025 at 5:58 PM
⏰ Only 1 day left to apply!
Applications for the EvoMG-DN PhD positions close tomorrow.
If you plan to apply, this is your final chance.
Submit your application here → www.evomg-dn.eu
#PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA
Applications for the EvoMG-DN PhD positions close tomorrow.
If you plan to apply, this is your final chance.
Submit your application here → www.evomg-dn.eu
#PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA
Our Maria successfully defended her MSc dissertation on Tuesday afternoon and still found the energy to present her work on the isoform-specific impact of mutations in CDKN2A in cancer again the following morning, at the 9th Annual Conference of ULisboa redeSAÚDE. 💻🧬 👏🍾 💪
November 28, 2025 at 12:03 AM
Our Maria successfully defended her MSc dissertation on Tuesday afternoon and still found the energy to present her work on the isoform-specific impact of mutations in CDKN2A in cancer again the following morning, at the 9th Annual Conference of ULisboa redeSAÚDE. 💻🧬 👏🍾 💪
Reposted by Disease Transcriptomics (NMorais) Lab
Before you submit your application, make sure you have everything ready:
✔ 2 referee details
✔ Academic transcripts
✔ Confirmation that you meet all eligibility criteria
You can still apply through our website → www.evomg-dn.eu
#PhD #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology
✔ 2 referee details
✔ Academic transcripts
✔ Confirmation that you meet all eligibility criteria
You can still apply through our website → www.evomg-dn.eu
#PhD #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology
November 27, 2025 at 10:07 AM
Before you submit your application, make sure you have everything ready:
✔ 2 referee details
✔ Academic transcripts
✔ Confirmation that you meet all eligibility criteria
You can still apply through our website → www.evomg-dn.eu
#PhD #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology
✔ 2 referee details
✔ Academic transcripts
✔ Confirmation that you meet all eligibility criteria
You can still apply through our website → www.evomg-dn.eu
#PhD #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology
Reposted by Disease Transcriptomics (NMorais) Lab
#Postdoc alert! We are looking for motivated individual with experience in computational systems biology to join our NetworkCommons initiative to benchmark and democratise network contextualisation methods across multiple applications. Deadline Dec 17th link here: tinyurl.com/yrrzxa94
Postdoctoral fellow - Petsalaki Group - NetworkCommons
Your group The Petsalaki, Saez-Rodriguez (EMBL-EBI) and Korcsmáros (Imperial College) groups develop cutting-edge computational and AI approaches to unravel cellular signalling and gene regulation fro...
tinyurl.com
November 26, 2025 at 5:05 PM
#Postdoc alert! We are looking for motivated individual with experience in computational systems biology to join our NetworkCommons initiative to benchmark and democratise network contextualisation methods across multiple applications. Deadline Dec 17th link here: tinyurl.com/yrrzxa94