Prof Paula Salgado
@pssalgado.bsky.social
Structural Microbiologist studies molecular details of C. difficile at Newcastle University, UK. (she/her) Interested in science, politics, theatre, and so much more. Views my own. https://salgadolab.org/
Reposted by Prof Paula Salgado
'Increases in overall hospital admissions, comorbidities and testing largely explained rising numbers, which also stemmed from an ageing population, demographic changes & more primary care antibiotic prescribing. (...) these did not fully account for increases, further determinants should be sought'
Nice new article on #cdif from colleagues. Looks at possible explanations for why there have been rises in CDI rates in England in recent years.
No great surprises in risk factors - age, comorbidities cancer and prior abx all raise risk of CDI.
But, ...
1/2
www.eurosurveillance.org/content/10.2...
No great surprises in risk factors - age, comorbidities cancer and prior abx all raise risk of CDI.
But, ...
1/2
www.eurosurveillance.org/content/10.2...
Factors driving increases in Clostridioides difficile infection rates in England: a national case−control study, 2019 to 2024
BACKGROUND Numbers of Clostridioides difficile infections (CDI) in England have risen since 2021, but for unclear reasons. AIM This study’s objective was to understand factors driving CDI increases, a...
www.eurosurveillance.org
September 22, 2026 at 12:56 PM
'Increases in overall hospital admissions, comorbidities and testing largely explained rising numbers, which also stemmed from an ageing population, demographic changes & more primary care antibiotic prescribing. (...) these did not fully account for increases, further determinants should be sought'
Reposted by Prof Paula Salgado
..what is interesting is that these factors don't fully explain the observed risk. There are some other factors that are increasing the risk of CDI. What are they, how can we identify them, and how can we modify them? All important Q's.
#hcai
#hcai
September 22, 2026 at 12:48 PM
..what is interesting is that these factors don't fully explain the observed risk. There are some other factors that are increasing the risk of CDI. What are they, how can we identify them, and how can we modify them? All important Q's.
#hcai
#hcai
Reposted by Prof Paula Salgado
Nice new article on #cdif from colleagues. Looks at possible explanations for why there have been rises in CDI rates in England in recent years.
No great surprises in risk factors - age, comorbidities cancer and prior abx all raise risk of CDI.
But, ...
1/2
www.eurosurveillance.org/content/10.2...
No great surprises in risk factors - age, comorbidities cancer and prior abx all raise risk of CDI.
But, ...
1/2
www.eurosurveillance.org/content/10.2...
Factors driving increases in Clostridioides difficile infection rates in England: a national case−control study, 2019 to 2024
BACKGROUND Numbers of Clostridioides difficile infections (CDI) in England have risen since 2021, but for unclear reasons. AIM This study’s objective was to understand factors driving CDI increases, a...
www.eurosurveillance.org
September 22, 2026 at 12:48 PM
Nice new article on #cdif from colleagues. Looks at possible explanations for why there have been rises in CDI rates in England in recent years.
No great surprises in risk factors - age, comorbidities cancer and prior abx all raise risk of CDI.
But, ...
1/2
www.eurosurveillance.org/content/10.2...
No great surprises in risk factors - age, comorbidities cancer and prior abx all raise risk of CDI.
But, ...
1/2
www.eurosurveillance.org/content/10.2...
Tfw when you’re on annual leave but still decide to check your email only to find out your grant got funded! #academicsky #PIlife
Happy Dance
ALT: Happy Dance
static.klipy.com
September 15, 2026 at 12:42 PM
Tfw when you’re on annual leave but still decide to check your email only to find out your grant got funded! #academicsky #PIlife
And that’s the end of another fantastic ICDS. A sad moment as Maja Rupnik steps down as organiser - but will always be a major presence! Thank you Maja!
September 10, 2026 at 2:37 PM
And that’s the end of another fantastic ICDS. A sad moment as Maja Rupnik steps down as organiser - but will always be a major presence! Thank you Maja!
Reposted by Prof Paula Salgado
Reposted by Prof Paula Salgado
Professor Dame Janet M Thornton DBE FMedSci FRS is awarded the Croonian Medal and Lecture 2027 for her pioneering work in protein structural and functional bioinformatics. #RSMedals https://royalsociety.org/medals-and-prizes/croonian-lecture/
August 27, 2026 at 10:53 AM
Professor Dame Janet M Thornton DBE FMedSci FRS is awarded the Croonian Medal and Lecture 2027 for her pioneering work in protein structural and functional bioinformatics. #RSMedals https://royalsociety.org/medals-and-prizes/croonian-lecture/
Reposted by Prof Paula Salgado
AlphaFold Server’s ligand menu just got a lot bigger and I almost missed it! You can now add any ligand from the wwPDB Chemical Component Dictionary. Just enter its CCD code 🥳
September 6, 2026 at 4:20 PM
AlphaFold Server’s ligand menu just got a lot bigger and I almost missed it! You can now add any ligand from the wwPDB Chemical Component Dictionary. Just enter its CCD code 🥳
Reposted by Prof Paula Salgado
Should be the biggest story today by some distance. Truly mad that it isn’t.
www.businessgreen.com/news/4535094...
www.businessgreen.com/news/4535094...
UN: World now all but certain to 'overshoot' critical 1.5C global warming threshold
UNEP sets out 'best-case' scenario of 1.8C for global average temperature rise, but maintains world can still limit, adapt to, and eventually reduce warming to or below 1.5C threshold in future
www.businessgreen.com
September 2, 2026 at 12:57 PM
Should be the biggest story today by some distance. Truly mad that it isn’t.
www.businessgreen.com/news/4535094...
www.businessgreen.com/news/4535094...
Reposted by Prof Paula Salgado
Free and open-source images, icons, and tools for creating scientific illustrations doi.org/10.59350/5zt... 🧪
Free and open-source images, icons, and tools for creating scientific illustrations
Phylopic, NIH Bioart, Bioicons, Scidraw, Open Science Art, Health Icons, Servier Medical Art, Biodiversity Heritage Library, the Noun Project, Segment Anything, Excalidraw, draw.io, Biographics
doi.org
May 3, 2026 at 10:08 AM
Free and open-source images, icons, and tools for creating scientific illustrations doi.org/10.59350/5zt... 🧪
Fabulous work, congratulations to all! Very cool S-layer structure!
Molecular architecture of colossal surface layers from hyperthermophilic archaea
Led by @idocaspy.bsky.social (Ido)
In collaboration with @mkrupovic.bsky.social and @vikramalva.bsky.social labs
doi.org/10.64898/202...
Led by @idocaspy.bsky.social (Ido)
In collaboration with @mkrupovic.bsky.social and @vikramalva.bsky.social labs
doi.org/10.64898/202...
August 23, 2026 at 7:24 PM
Fabulous work, congratulations to all! Very cool S-layer structure!
En route to meet fellow scientists, innovators, entrepreneurs, science communicators and more. Excited for interacting with people outside my usual sphere!
August 21, 2026 at 10:42 AM
En route to meet fellow scientists, innovators, entrepreneurs, science communicators and more. Excited for interacting with people outside my usual sphere!
Reposted by Prof Paula Salgado
Keynote announced!
We're delighted to welcome Prof. Laura Spagnolo (University of Glasgow) as keynote speaker for the CCP4 Northern Structural Biology Meeting 2026
11–13 Nov | Newcastle
Free to attend
cc @lauraspagnolo.bsky.social
#StructuralBiology #CryoEM #CCP4
We're delighted to welcome Prof. Laura Spagnolo (University of Glasgow) as keynote speaker for the CCP4 Northern Structural Biology Meeting 2026
11–13 Nov | Newcastle
Free to attend
cc @lauraspagnolo.bsky.social
#StructuralBiology #CryoEM #CCP4
CCP4 Northern meeting 2026: Keynote Speaker Laura Spagnolo
CCP4 Northern meeting 2026 keynote speaker announced: Prof. Laura Spagnolo (Glasgow) will speak 11–13 Nov in Newcastle.
nusbf.ncl.ac.uk
August 19, 2026 at 3:20 PM
Keynote announced!
We're delighted to welcome Prof. Laura Spagnolo (University of Glasgow) as keynote speaker for the CCP4 Northern Structural Biology Meeting 2026
11–13 Nov | Newcastle
Free to attend
cc @lauraspagnolo.bsky.social
#StructuralBiology #CryoEM #CCP4
We're delighted to welcome Prof. Laura Spagnolo (University of Glasgow) as keynote speaker for the CCP4 Northern Structural Biology Meeting 2026
11–13 Nov | Newcastle
Free to attend
cc @lauraspagnolo.bsky.social
#StructuralBiology #CryoEM #CCP4
Reposted by Prof Paula Salgado
My mind is still blown by this, decades of using bunsen burners and teaching a wide range of students how to use them correctly and now.... we don't even need them. Crazy.
#MicroSky
journals.asm.org/doi/full/10....
#MicroSky
journals.asm.org/doi/full/10....
As a component of aseptic technique, Bunsen burners do not universally decrease deposition of microbe-containing particles | Microbiology Spectrum
The ability to manipulate and control microbial presence in built environments is
imperative to research and medicine. The lack of documented evidence relating Bunsen
burner use and airborne contamina...
journals.asm.org
August 19, 2026 at 7:11 PM
My mind is still blown by this, decades of using bunsen burners and teaching a wide range of students how to use them correctly and now.... we don't even need them. Crazy.
#MicroSky
journals.asm.org/doi/full/10....
#MicroSky
journals.asm.org/doi/full/10....
Reposted by Prof Paula Salgado
🌲 A walk in the woods, an afternoon in the park, a day on the trail... sometimes a tick comes home with you.
A few precautions can reduce the risk of tick bites. And when you get back, remember the tick check.
More tips 👉️ bit.ly/ECDCSafeSummer
#SafeSummer #Ticks #IDsky #EpiSky
A few precautions can reduce the risk of tick bites. And when you get back, remember the tick check.
More tips 👉️ bit.ly/ECDCSafeSummer
#SafeSummer #Ticks #IDsky #EpiSky
August 17, 2026 at 2:30 PM
🌲 A walk in the woods, an afternoon in the park, a day on the trail... sometimes a tick comes home with you.
A few precautions can reduce the risk of tick bites. And when you get back, remember the tick check.
More tips 👉️ bit.ly/ECDCSafeSummer
#SafeSummer #Ticks #IDsky #EpiSky
A few precautions can reduce the risk of tick bites. And when you get back, remember the tick check.
More tips 👉️ bit.ly/ECDCSafeSummer
#SafeSummer #Ticks #IDsky #EpiSky
Very nice work, congratulations to all!
Our preprint is now published!
Out Now! Quinone-transporting filaments expand bioenergetic capacity in Gram-positive Bacillota #MicroSky
August 17, 2026 at 2:04 PM
Very nice work, congratulations to all!
Very cool work, congratulations to all!
New preprint out - Jenn’s hard work over the last few years collaborating with @jnb-lab.bsky.social, Overkleeft Lab in Leiden, Spencer Williams, Hannah Bridges at Cryosparc and @pmoyniha.bsky.social. Feat. her beautiful 1.5A cryo structure with a covalent inhibitor 😍. www.biorxiv.org/content/10.6...
August 15, 2026 at 9:43 AM
Very cool work, congratulations to all!
Two papers accepted in the same week! Massive congratulations to Anna Barwinska-Sendra and Kacper Sendra, the main drivers of this work! Watch this space for details and links soon!
Joyful Celebration
ALT: Joyful Celebration
static.klipy.com
August 12, 2026 at 11:18 AM
Two papers accepted in the same week! Massive congratulations to Anna Barwinska-Sendra and Kacper Sendra, the main drivers of this work! Watch this space for details and links soon!
Reposted by Prof Paula Salgado
Permanent academic position as a Lecturer in cryo-ET open at York. We are looking for someone to lead a research program making the most of the stunning advances occurring in cryo-ET. It's a research and teaching post but with a focus on research in the early years. jobs.york.ac.uk/vacancy/lect...
Jobs - The University of York
jobs.york.ac.uk
August 10, 2026 at 8:33 PM
Permanent academic position as a Lecturer in cryo-ET open at York. We are looking for someone to lead a research program making the most of the stunning advances occurring in cryo-ET. It's a research and teaching post but with a focus on research in the early years. jobs.york.ac.uk/vacancy/lect...
Reposted by Prof Paula Salgado
A single DNA methylation site regulates cell fate during Clostridioides difficile sporulation: dx.plos.org/10.1371/jour...
A single DNA methylation site regulates cell fate during Clostridioides difficile sporulation
Author summary Most bacteria use orphan DNA methyltransferases to modify their genomes and alter their gene expression. While these modifications lead to changes in a bacterium’s phenotype, the specif...
dx.plos.org
August 10, 2026 at 11:39 AM
A single DNA methylation site regulates cell fate during Clostridioides difficile sporulation: dx.plos.org/10.1371/jour...
Brilliant PhD student Ellie Rockliff is off to Australia for her year in Prof Dena Lyras’ lab at Monash. Bitter sweet moment as we wish her all the best + we’ll miss you! #ProudPI
August 6, 2026 at 12:55 PM
Brilliant PhD student Ellie Rockliff is off to Australia for her year in Prof Dena Lyras’ lab at Monash. Bitter sweet moment as we wish her all the best + we’ll miss you! #ProudPI
Reposted by Prof Paula Salgado
Ok, time to feel old – for a good cause 😃
I was in the middle of my PhD when our journal was launched.
An online-only journal at a time when most others were not.
This is by definition a VERY special issue. Have a look at what papers we're looking for and be a part of the future of the journal!
I was in the middle of my PhD when our journal was launched.
An online-only journal at a time when most others were not.
This is by definition a VERY special issue. Have a look at what papers we're looking for and be a part of the future of the journal!
August 5, 2026 at 11:35 AM
Ok, time to feel old – for a good cause 😃
I was in the middle of my PhD when our journal was launched.
An online-only journal at a time when most others were not.
This is by definition a VERY special issue. Have a look at what papers we're looking for and be a part of the future of the journal!
I was in the middle of my PhD when our journal was launched.
An online-only journal at a time when most others were not.
This is by definition a VERY special issue. Have a look at what papers we're looking for and be a part of the future of the journal!
Reposted by Prof Paula Salgado
According to the parliamentary annual report & accounts for the 2025/26 financial year, the cost of subsidising the bars in the House of Commons alone was around £5.8 million.
Meanwhile, to save £3 million less than that, Jodrell Bank is being defunded and shut down.
share.google/MRHIvCsCsKoc...
Meanwhile, to save £3 million less than that, Jodrell Bank is being defunded and shut down.
share.google/MRHIvCsCsKoc...
Jodrell Bank's Lovell telescope faces axe in science cuts, BBC understands
Astronomers warn it would tear the heart out of UK science, and leave a generation untrained.
share.google
August 1, 2026 at 7:35 AM
According to the parliamentary annual report & accounts for the 2025/26 financial year, the cost of subsidising the bars in the House of Commons alone was around £5.8 million.
Meanwhile, to save £3 million less than that, Jodrell Bank is being defunded and shut down.
share.google/MRHIvCsCsKoc...
Meanwhile, to save £3 million less than that, Jodrell Bank is being defunded and shut down.
share.google/MRHIvCsCsKoc...
Reposted by Prof Paula Salgado
Earlier this year UKRI launched a funding call to invest £40M in ONE AI lab.
www.ukri.org/opportunity/...
For some unknown reason they decided to fund TWO AI labs at the cost of £60M.
An extra £20M.
Just found.
That's the equivalent of 7 more years of Jodrell Bank.
www.ukri.org/news/ukri-la...
www.ukri.org/opportunity/...
For some unknown reason they decided to fund TWO AI labs at the cost of £60M.
An extra £20M.
Just found.
That's the equivalent of 7 more years of Jodrell Bank.
www.ukri.org/news/ukri-la...
July 27, 2026 at 5:52 PM
Earlier this year UKRI launched a funding call to invest £40M in ONE AI lab.
www.ukri.org/opportunity/...
For some unknown reason they decided to fund TWO AI labs at the cost of £60M.
An extra £20M.
Just found.
That's the equivalent of 7 more years of Jodrell Bank.
www.ukri.org/news/ukri-la...
www.ukri.org/opportunity/...
For some unknown reason they decided to fund TWO AI labs at the cost of £60M.
An extra £20M.
Just found.
That's the equivalent of 7 more years of Jodrell Bank.
www.ukri.org/news/ukri-la...