Renae Ryan
@renaeryan.bsky.social
Professor @ University of Sydney; interested in membrane transport proteins, biophysics, pharmacology and diversity and inclusion in STEMM. Views expressed here are my own. She/her.
Reposted by Renae Ryan
Seminar alert! We are excited to announce our next CCeMMP Seminar will be with Dr. Rosemary Cater from the Institute for Molecular Bioscience, UQ.
Title: Structural and Mechanistic Insights into Nutrient Transport at the Blood Brain Barrier.
More info & register: ccemmp.org/events/ccemm...
Title: Structural and Mechanistic Insights into Nutrient Transport at the Blood Brain Barrier.
More info & register: ccemmp.org/events/ccemm...
February 22, 2026 at 11:28 PM
Seminar alert! We are excited to announce our next CCeMMP Seminar will be with Dr. Rosemary Cater from the Institute for Molecular Bioscience, UQ.
Title: Structural and Mechanistic Insights into Nutrient Transport at the Blood Brain Barrier.
More info & register: ccemmp.org/events/ccemm...
Title: Structural and Mechanistic Insights into Nutrient Transport at the Blood Brain Barrier.
More info & register: ccemmp.org/events/ccemm...
Reposted by Renae Ryan
What an amazing group of people at the 2026 Lorne Protein Meeting. Hope we see many of you there again in 2027!
February 17, 2026 at 5:25 AM
What an amazing group of people at the 2026 Lorne Protein Meeting. Hope we see many of you there again in 2027!
Reposted by Renae Ryan
Yan Jiang is the next Anders session speaker presenting her work on the SLC1A transporter. @lorneproteins.bsky.social
February 9, 2026 at 9:18 AM
Yan Jiang is the next Anders session speaker presenting her work on the SLC1A transporter. @lorneproteins.bsky.social
Reposted by Renae Ryan
Lorne Proteins 2026 🏖️ Leach Lecturer Carol Robinson, Oxford, on establishing mass spec as a viable technique for structure/function studies; and John Kuriyan, Vanderbilt University, on the structural plasticity and evolutionary potential of DNA clamp loaders.
🔗 Register now: www.lorneproteins.org
🔗 Register now: www.lorneproteins.org
January 14, 2026 at 10:31 AM
Lorne Proteins 2026 🏖️ Leach Lecturer Carol Robinson, Oxford, on establishing mass spec as a viable technique for structure/function studies; and John Kuriyan, Vanderbilt University, on the structural plasticity and evolutionary potential of DNA clamp loaders.
🔗 Register now: www.lorneproteins.org
🔗 Register now: www.lorneproteins.org
Reposted by Renae Ryan
Our paper on the human carnitine transporter OCTN2 (SLC22A5) is out in @natcomms.nature.com! We solved structures of OCTN2 in multiple states and explored how carnitine transport is Na⁺-dependent, providing a framework for understanding SPCD disease causing variants and drug interactions.
Structural basis of sodium ion-dependent carnitine transport by OCTN2
Nature Communications - Carnitine uptake by OCTN2 supports fatty acid metabolism. Here, authors report cryo-EM structures of human OCTN2, revealing the mechanism of sodium ion-dependent carnitine...
rdcu.be
January 8, 2026 at 12:05 AM
Our paper on the human carnitine transporter OCTN2 (SLC22A5) is out in @natcomms.nature.com! We solved structures of OCTN2 in multiple states and explored how carnitine transport is Na⁺-dependent, providing a framework for understanding SPCD disease causing variants and drug interactions.
Congratulations Parteek Rosie!!!
Congratulations to the Cater Lab's first ever graduate Parteek! Bachelor of Advanced Scince with First Class Honours - we are SO proud of you! Looking forward to another year of fun in the lab together in 2026! 🎓🔬🧪✨
December 18, 2025 at 8:04 AM
Congratulations Parteek Rosie!!!
Reposted by Renae Ryan
🏖️ 🌊 🤩 Christopher Barnes on molecular characterisation of vulnerable conserved coronavirus antigen:antibody complexes; and Rina Rosenzweig on chaperones recognition and prevention of protein misfolding in neurodegenerative conditions—at Lorne Proteins 2026!
🔗 Register now: www.lorneproteins.org
🔗 Register now: www.lorneproteins.org
December 11, 2025 at 11:29 PM
🏖️ 🌊 🤩 Christopher Barnes on molecular characterisation of vulnerable conserved coronavirus antigen:antibody complexes; and Rina Rosenzweig on chaperones recognition and prevention of protein misfolding in neurodegenerative conditions—at Lorne Proteins 2026!
🔗 Register now: www.lorneproteins.org
🔗 Register now: www.lorneproteins.org
Reposted by Renae Ryan
I am pleased to announce the release of ProteinDJ v2! This is a major update that integrates BindCraft into the pipeline as an alternative to RFdiffusion for binder generation. You can try it out here: github.com/PapenfussLab/proteindj
#ProteinDJ #BindCraft #ProteinDesign @wehi-research.bsky.social
#ProteinDJ #BindCraft #ProteinDesign @wehi-research.bsky.social
November 25, 2025 at 3:01 AM
I am pleased to announce the release of ProteinDJ v2! This is a major update that integrates BindCraft into the pipeline as an alternative to RFdiffusion for binder generation. You can try it out here: github.com/PapenfussLab/proteindj
#ProteinDJ #BindCraft #ProteinDesign @wehi-research.bsky.social
#ProteinDJ #BindCraft #ProteinDesign @wehi-research.bsky.social
Reposted by Renae Ryan
🚨 Final Week to Submit Abstracts!
This is your last week to be part of Australia’s most iconic protein science meeting. Don’t miss your chance to share your research on the global stage.
👉 Submit now: www.lorneproteins.org
#LorneProteins #AbstractsClosing #ProteinScience
This is your last week to be part of Australia’s most iconic protein science meeting. Don’t miss your chance to share your research on the global stage.
👉 Submit now: www.lorneproteins.org
#LorneProteins #AbstractsClosing #ProteinScience
October 20, 2025 at 12:05 AM
🚨 Final Week to Submit Abstracts!
This is your last week to be part of Australia’s most iconic protein science meeting. Don’t miss your chance to share your research on the global stage.
👉 Submit now: www.lorneproteins.org
#LorneProteins #AbstractsClosing #ProteinScience
This is your last week to be part of Australia’s most iconic protein science meeting. Don’t miss your chance to share your research on the global stage.
👉 Submit now: www.lorneproteins.org
#LorneProteins #AbstractsClosing #ProteinScience
Reposted by Renae Ryan
🌟 Indigenous Researcher Award
Support for indigenous scientists to attend Lorne Proteins through travel and registration bursaries.
Learn more and make a difference here 👉 www.lorneproteins.org/conferencesu...
#LorneProteins #FutureScientists #ScienceSupport
Support for indigenous scientists to attend Lorne Proteins through travel and registration bursaries.
Learn more and make a difference here 👉 www.lorneproteins.org/conferencesu...
#LorneProteins #FutureScientists #ScienceSupport
October 15, 2025 at 10:34 PM
🌟 Indigenous Researcher Award
Support for indigenous scientists to attend Lorne Proteins through travel and registration bursaries.
Learn more and make a difference here 👉 www.lorneproteins.org/conferencesu...
#LorneProteins #FutureScientists #ScienceSupport
Support for indigenous scientists to attend Lorne Proteins through travel and registration bursaries.
Learn more and make a difference here 👉 www.lorneproteins.org/conferencesu...
#LorneProteins #FutureScientists #ScienceSupport
Reposted by Renae Ryan
Are you within 5 years of your PhD? Apply now for the Anders Early Career Award, honouring Professor Robin Anders and recognising excellence in emerging protein scientists.
🎤 Speaking slot + 💰 $500 prize
📅 Apply by Friday 24 October 2025
👉 www.lorneproteins.org
#LorneProteins #AndersAward
🎤 Speaking slot + 💰 $500 prize
📅 Apply by Friday 24 October 2025
👉 www.lorneproteins.org
#LorneProteins #AndersAward
October 13, 2025 at 11:05 PM
Are you within 5 years of your PhD? Apply now for the Anders Early Career Award, honouring Professor Robin Anders and recognising excellence in emerging protein scientists.
🎤 Speaking slot + 💰 $500 prize
📅 Apply by Friday 24 October 2025
👉 www.lorneproteins.org
#LorneProteins #AndersAward
🎤 Speaking slot + 💰 $500 prize
📅 Apply by Friday 24 October 2025
👉 www.lorneproteins.org
#LorneProteins #AndersAward
Reposted by Renae Ryan
Cicada x Tech23 talks are up! youtu.be/vXbfEjVGry0?...
Redesigning Resources From The Cell Membrane Up | Caitlin Byrt (MTE)
YouTube video by Cicada Innovations
youtu.be
October 1, 2025 at 11:05 AM
Cicada x Tech23 talks are up! youtu.be/vXbfEjVGry0?...
Reposted by Renae Ryan
I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5)
doi.org/10.1101/2025.09.24.678028 #proteindesign
doi.org/10.1101/2025.09.24.678028 #proteindesign
September 28, 2025 at 9:16 PM
I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5)
doi.org/10.1101/2025.09.24.678028 #proteindesign
doi.org/10.1101/2025.09.24.678028 #proteindesign
Reposted by Renae Ryan
𝐓𝐡𝐞 𝐀𝐧𝐝𝐞𝐫𝐬 𝐀𝐰𝐚𝐫𝐝 recognises up to 5️⃣ scientists who are within 5 years of their PhD, with a talk secured in a dedicated session! It’s always a highlight of the meeting & a fantastic opportunity to showcase exciting new science 🤩
𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐜𝐥𝐨𝐬𝐞 𝟐𝟒 𝐎𝐜𝐭𝐨𝐛𝐞𝐫 𝟐𝟎𝟐𝟓:
www.lorneproteins.org/submissions
𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐜𝐥𝐨𝐬𝐞 𝟐𝟒 𝐎𝐜𝐭𝐨𝐛𝐞𝐫 𝟐𝟎𝟐𝟓:
www.lorneproteins.org/submissions
September 25, 2025 at 3:28 AM
𝐓𝐡𝐞 𝐀𝐧𝐝𝐞𝐫𝐬 𝐀𝐰𝐚𝐫𝐝 recognises up to 5️⃣ scientists who are within 5 years of their PhD, with a talk secured in a dedicated session! It’s always a highlight of the meeting & a fantastic opportunity to showcase exciting new science 🤩
𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐜𝐥𝐨𝐬𝐞 𝟐𝟒 𝐎𝐜𝐭𝐨𝐛𝐞𝐫 𝟐𝟎𝟐𝟓:
www.lorneproteins.org/submissions
𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐜𝐥𝐨𝐬𝐞 𝟐𝟒 𝐎𝐜𝐭𝐨𝐛𝐞𝐫 𝟐𝟎𝟐𝟓:
www.lorneproteins.org/submissions
Reposted by Renae Ryan
The outer membrane of Gram-negative bacteria blocks many antibiotics. Our latest work reveals that L-type pyocins bypass this barrier by inactivating the BAM complex, killing Pseudomonas aeruginosa without entering the cell, providing a new blueprint for beating antibiotic resistance.
A Protein Antibiotic Inhibits the BAM Complex to Kill Without Cell Entry
Many antibiotics are ineffective against Gram-negative pathogens such as Pseudomonas aeruginosa because they cannot penetrate the bacterial outer membrane. Here, we show that protein antibiotics calle...
www.biorxiv.org
September 20, 2025 at 9:29 AM
The outer membrane of Gram-negative bacteria blocks many antibiotics. Our latest work reveals that L-type pyocins bypass this barrier by inactivating the BAM complex, killing Pseudomonas aeruginosa without entering the cell, providing a new blueprint for beating antibiotic resistance.
Reposted by Renae Ryan
👕✨ Design the next Lorne Protein Conference T-shirt!
Entries close 17 Oct – don’t miss your chance to show off your creativity and cement your place in the history of Lorne Proteins 🤓
👉 Submit your design-see the link below...
📢 And don’t forget to submit your abstract by 24 Oct!
#LorneProteins
Entries close 17 Oct – don’t miss your chance to show off your creativity and cement your place in the history of Lorne Proteins 🤓
👉 Submit your design-see the link below...
📢 And don’t forget to submit your abstract by 24 Oct!
#LorneProteins
September 16, 2025 at 9:16 PM
👕✨ Design the next Lorne Protein Conference T-shirt!
Entries close 17 Oct – don’t miss your chance to show off your creativity and cement your place in the history of Lorne Proteins 🤓
👉 Submit your design-see the link below...
📢 And don’t forget to submit your abstract by 24 Oct!
#LorneProteins
Entries close 17 Oct – don’t miss your chance to show off your creativity and cement your place in the history of Lorne Proteins 🤓
👉 Submit your design-see the link below...
📢 And don’t forget to submit your abstract by 24 Oct!
#LorneProteins
Reposted by Renae Ryan
Momentum is building! Join us for the 51st Lorne Proteins Conference Feb 8–12, 2026, Mantra Lorne on the Great Ocean Road, for fun networking activities 🏐 🎾 🥗 🪩 and breathtaking surf-coast accessibility 🏖️ 🏊 🏄 in the generous breaks between sessions!
🔗 Register here: www.lorneproteins.org/register
🔗 Register here: www.lorneproteins.org/register
September 16, 2025 at 12:57 AM
Momentum is building! Join us for the 51st Lorne Proteins Conference Feb 8–12, 2026, Mantra Lorne on the Great Ocean Road, for fun networking activities 🏐 🎾 🥗 🪩 and breathtaking surf-coast accessibility 🏖️ 🏊 🏄 in the generous breaks between sessions!
🔗 Register here: www.lorneproteins.org/register
🔗 Register here: www.lorneproteins.org/register
Reposted by Renae Ryan
🥁🥁🥁
The 51st Lorne Conference on Protein Structure and Function is officially live! After the resounding success of the 50th Lorne Conference in 2025 celebrating five decades of pioneering science and community, the legacy continues... 🏄🏖️🌞
February 8–12, 2026
Register here: www.lorneproteins.org
The 51st Lorne Conference on Protein Structure and Function is officially live! After the resounding success of the 50th Lorne Conference in 2025 celebrating five decades of pioneering science and community, the legacy continues... 🏄🏖️🌞
February 8–12, 2026
Register here: www.lorneproteins.org
August 21, 2025 at 4:38 AM
🥁🥁🥁
The 51st Lorne Conference on Protein Structure and Function is officially live! After the resounding success of the 50th Lorne Conference in 2025 celebrating five decades of pioneering science and community, the legacy continues... 🏄🏖️🌞
February 8–12, 2026
Register here: www.lorneproteins.org
The 51st Lorne Conference on Protein Structure and Function is officially live! After the resounding success of the 50th Lorne Conference in 2025 celebrating five decades of pioneering science and community, the legacy continues... 🏄🏖️🌞
February 8–12, 2026
Register here: www.lorneproteins.org
Reposted by Renae Ryan
Microdosing delight to combat stress; interesting concept, backed by neuroscience. Was a pleasure to comment on the very excellent work of @drrachelbarr.bsky.social on how the experience of delight can tune down our stress response. @brainandmindcentre.bsky.social www.smh.com.au/lifestyle/he...
As we stress more than ever, is it time to ‘microdose delight’?
Our brains are not built to handle the daily threats modern humans face. But there’s a trick that may help them.
www.smh.com.au
August 11, 2025 at 10:03 AM
Microdosing delight to combat stress; interesting concept, backed by neuroscience. Was a pleasure to comment on the very excellent work of @drrachelbarr.bsky.social on how the experience of delight can tune down our stress response. @brainandmindcentre.bsky.social www.smh.com.au/lifestyle/he...
Reposted by Renae Ryan
Congratulations to the nine researchers and teams placed among the finalists in the 2025 @eurekaprizes.bsky.social 👏
The Prize is among the top science awards in Australia, honouring the calibre of research and innovation, celebrating leaders in their field.
Read more: go.sydney.edu.au/2l5jnZ
The Prize is among the top science awards in Australia, honouring the calibre of research and innovation, celebrating leaders in their field.
Read more: go.sydney.edu.au/2l5jnZ
July 31, 2025 at 12:03 AM
Congratulations to the nine researchers and teams placed among the finalists in the 2025 @eurekaprizes.bsky.social 👏
The Prize is among the top science awards in Australia, honouring the calibre of research and innovation, celebrating leaders in their field.
Read more: go.sydney.edu.au/2l5jnZ
The Prize is among the top science awards in Australia, honouring the calibre of research and innovation, celebrating leaders in their field.
Read more: go.sydney.edu.au/2l5jnZ
Beautiful and important work. Congratulations @thamlab.bsky.social and team!
Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI
August 1, 2025 at 2:40 AM
Beautiful and important work. Congratulations @thamlab.bsky.social and team!
Reposted by Renae Ryan
Happy to report our enzyme found a home! rdcu.be/eaGXG New kid on the block P450 O-demethylase SyoA-the specificity of a monooxygenase with the simplicity of catalysis driven by peroxide. Retrofit your P450 with this active site chemistry today! #lignin #syringol Out today in Nature Communications.
February 21, 2025 at 12:17 AM
Happy to report our enzyme found a home! rdcu.be/eaGXG New kid on the block P450 O-demethylase SyoA-the specificity of a monooxygenase with the simplicity of catalysis driven by peroxide. Retrofit your P450 with this active site chemistry today! #lignin #syringol Out today in Nature Communications.
Reposted by Renae Ryan
‘We want women to have role models’: how Sydney University is enticing more female academics to engineering
‘We want women to have role models’: how Sydney University is enticing more female academics to engineering
A mass recruitment campaign with roles reserved solely for women has been launched at a faculty where fewer than one in five academics are female
*
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When Dr Jacqueline Thomas started her academic career in civil engineering a decade ago, she was one of just two full-time women in the school. Thomas had returned to Australia after a stint in Africa to teach a new humanitarian engineering major at the University of Sydney, the first of its kind in the country.
“It was crazy, it really took me by surprise,” she said. “When I started, I just thought, ‘great, I got the job, perfect’. And then I realised.” Continue reading...
www.theguardian.com
July 27, 2025 at 3:03 PM
‘We want women to have role models’: how Sydney University is enticing more female academics to engineering
Reposted by Renae Ryan
Our article showing energy production from air alone is in PNAS today. This paper provides an ultimate biochemical proof that microbes can survive simply by 'making' energy from air (making two ATP per molecule atmospheric H2 consumed) and has biotech applications. www.pnas.org/doi/10.1073/...
ATP synthesis driven by atmospheric hydrogen concentrations | PNAS
All cells require a continuous supply of the universal energy currency, adenosine
triphosphate (ATP), to drive countless cellular reactions. The un...
www.pnas.org
July 25, 2025 at 12:54 AM
Our article showing energy production from air alone is in PNAS today. This paper provides an ultimate biochemical proof that microbes can survive simply by 'making' energy from air (making two ATP per molecule atmospheric H2 consumed) and has biotech applications. www.pnas.org/doi/10.1073/...
Reposted by Renae Ryan
We are excited to share our EVENTS for #BlackInBiophysicsWeek 2025!!! We will be host #BIBPSWeek from Monday, 5/26 to Friday 5/30.
RT and help us spread the word!
A thread of Events below
#BIBPS25
#BlackInBiophysics
@biophysicalsoc.bsky.social
@blackinx.bsky.social
RT and help us spread the word!
A thread of Events below
#BIBPS25
#BlackInBiophysics
@biophysicalsoc.bsky.social
@blackinx.bsky.social
May 19, 2025 at 6:15 PM
We are excited to share our EVENTS for #BlackInBiophysicsWeek 2025!!! We will be host #BIBPSWeek from Monday, 5/26 to Friday 5/30.
RT and help us spread the word!
A thread of Events below
#BIBPS25
#BlackInBiophysics
@biophysicalsoc.bsky.social
@blackinx.bsky.social
RT and help us spread the word!
A thread of Events below
#BIBPS25
#BlackInBiophysics
@biophysicalsoc.bsky.social
@blackinx.bsky.social