A self-organized geometry sensing oscillator spatially regulates cell division in archaea https://www.biorxiv.org/content/10.64898/2026.07.23.738820v1

Sub-cellular architectures arise through integrating signaling and structure. @edenchang.bsky.social and @zjmaggiexu.bsky.social show how coupling reaction-diffusion signaling to protein condensation provides a tunable, regulatable landscape for sub-cellular structure www.biorxiv.org/content/10.6...

We enjoyed putting our heads together with the Jakob and Freddolino labs to find that polyphosphate modulates the formation of functional RNA-protein condensates in response to nitrogen-starvation stress!
journals.plos.org/plosbiology/...

In the context of carboxysome positioning, @azaldegui.bsky.social found that the aggregation of a bacterial microcompartment is prevented by a self-organizing DNA-binding ATPase! #SingleMolecule #SuperResolution #Microscopy
with @cellforganized.bsky.social and JianLiu
doi.org/10.64898/202...

Xiaofeng combined 2D live-cell single-particle tracking with 3D simulations to specifically measure the bacterial nucleoid accessibility and viscosity! Our preprint describes how these nucleoid properties respond to cellular processes! Code is available too.
www.biorxiv.org/content/10.6...

Now published in Protein Science: Dan used single-molecule and SOFI microscopies to visualize curli fibers (the major component of E. coli biofilms) on living cells! onlinelibrary.wiley.com/doi/10.1002/...

Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB https://www.biorxiv.org/content/10.1101/2025.11.19.689047v1

Now in print: @lortzrodz.bsky.social with @schraderlab.bsky.social found that the stress-induced transition of the material properties of bacterial ribonucleoprotein bodies repurposes them from sites of mRNA decay to reservoirs for mRNA storage.
@natcomms.nature.com

www.nature.com/articles/s41...

New PrePrint from the Vecchiarelli and Mosalaganti (@shyamalm.bsky.social) labs! 🧵

Collaboration with the Giessen and Pi labs

Congratulations to co-first authors Y Hoang (@hoanghamyy.bsky.social) and Pankaj Jadhav!

www.biorxiv.org/content/10.1...

Engineering Spatial Control of Bacterial Organelles https://www.biorxiv.org/content/10.1101/2025.09.22.677801v1

Interferometric Image Scanning Microscopy for label-free imaging at 120 nm resolution inside live cells https://www.biorxiv.org/content/10.1101/2025.09.19.677416v1

Dps binds and protects DNA in starved Escherichia coli with minimal effect on chromosome accessibility, dynamics and organisation https://www.biorxiv.org/content/10.1101/2025.08.31.673347v1

New @biorxiv-microbiol.bsky.social PrePrint from the Vecchiarelli Lab! 🧵
In collaboration with Jian Liu's lab at Johns Hopkins

doi.org/10.1101/2025...

Congratulations to first author Jordan Byrne!
@sickbyrne.bsky.social

P.S. She is looking for jobs!

Pls ReSkeet

Tuning the interaction of a ParA-type ATPase with its partner separates bacterial organelle positioning from partitioning https://www.biorxiv.org/content/10.1101/2025.05.22.655647v1

The hooding ceremony was a chance to celebrate these 2024 🎓 graduates all over again!

New @biorxiv-microbiol.bsky.social Pre-Print from the Vecchiarelli Lab! 🧵

doi.org/10.1101/2025...

Congratulations to first author Claire Dudley!
@claire-dudley.bsky.social

Pls ReSkeet