Nature Reviews Gastroenterology & Hepatology, Published online: 09 September 2026; doi:10.1038/s41575-026-01259-9A notable subset of people with inflammatory bowel disease remain unwell despite objective remission. Their ‘residual burden’ is too often misinterpreted as inflammation and can be treated as such. These symptoms, not attributable to active inflammation, deserve to be recognized as a treatment target in their own right and managed alongside disease control.

Thunder generates atmospheric acoustic waves that couple into the ground, producing seismic signals called “thunderquakes.” Although widely observed, this atmosphere-solid Earth conversion has rarely ...

While excess rainfall is associated with mosquito-borne disease because it supports mosquito breeding, drought may also counterintuitively increase disease transmission by altering mosquito and host b...

The immune system’s central function is to maintain homeostasis by guarding the organism against dangerous external and internal stressors. Immunity’s operational toolbox contains diverse processes, s...

First comprehensive map of the vagus nerve may point to more precise stimulation therapies

Obesity is increasingly managed with medications as disease-modifying therapies, reflecting its role as a gateway disease driving metabolic, cardiovascular, reproductive, neuropsychiatric, and mechani...

Ancient pots shift the nexus of chocolatemaking from Central America to modern Ecuador

Scientists will test an antiviral drug and an antibody cocktail designed to tame the burgeoning outbreak

Ancient pathogen DNA from animals elucidates the origin and evolution of infectious diseases