Paul Chrystal
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pwchrystal.bsky.social
Paul Chrystal
@pwchrystal.bsky.social
Research Associate at University of Toronto studying inherited retinal dystrophy.
Pinned
How does one gene perform different functions in different tissues? Our new publication in @CommsBio sheds some light on the disparate roles of Usher Syndrome disease gene PCDH15.
www.nature.com/articles/s42...
Reposted by Paul Chrystal
Gretl Baghdadi has earned the Nyman Scholarship from CSB for her studies in plant sciences and her supportive role in the @artsci.utoronto.ca community.
Read on for her advice to first years and the surprising path that drew her to plant research.
csb.utoronto.ca/nyman-schola...
Nyman Scholarship earned by paying it forward in research and student life - Department of Cell & Systems Biology
Gretl Baghdadi mentors fellow students while also pursuing rigourous research in the Christendat Lab, earning her the Nyman Scholarship from CSB
csb.utoronto.ca
September 28, 2026 at 8:58 PM
Check out this wonderful study of the mosaic organization of the photoreceptor cells in the turquoise killifish by my friend and colleague @nclnoel.bsky.social. The retina is so stunningly beautiful 😍
September 28, 2026 at 1:43 AM
Reposted by Paul Chrystal
Our collaborative paper on snake coiling is now out in the latest issue of @currentbiology.bsky.social and featured on the cover! 🎉 Delighted to see our work highlighted this way. You can read it here: authors.elsevier.com/c/1ni9h3QW8S...
@helsinki-biotech.bsky.social @helsinki.fi
September 22, 2026 at 8:10 AM
Reposted by Paul Chrystal
A surprising insight into the impressive architecture of developing embryos is revealed in a paper in @dev-journal.bsky.social by researchers in CSB.
csb.utoronto.ca/pulling-a-ri...
Pulling a ring on it: Camsap2 protein leads to tension in zebrafish embryos by coordinating distinct pathways - Department of Cell & Systems Biology
Fascinating surprise as Camsap2 protein's unique signalling role to actin-based processes in the embryo revealed by Bruce lab
csb.utoronto.ca
September 18, 2026 at 8:39 PM
Reposted by Paul Chrystal
On Usher Syndrome Awareness Day we are sharing some of the realities of living with Usher syndrome from people who know it first-hand. We want to remind you we are here to listen, help, cheer & support you and your family every step of the way. 💚

#RareDisease #UsherSyndromeAwarenessDay #Speirgorm
September 19, 2026 at 3:28 PM
Reposted by Paul Chrystal
#ICYMI: Dr. Brian Ballios, Clinician Scientist @dkjei-uhn.bsky.social, was recently featured on The Retina Channel podcast, discussing the latest advances in inherited retinal diseases (IRDs).

Listen to the full episode >> bit.ly/4iuq2KF
@uhn.ca @uhnresearch.ca @kbi-uhn.bsky.social
September 14, 2026 at 8:02 PM
Congratulations to Andrés Avelar for winning the F Michael Barrett Award for best poster today at @uoftcellsysbiol.bsky.social! You've worked super hard over the last 4 months in the Tropepe lab and truely earned this accolade!
September 3, 2026 at 1:11 AM
Reposted by Paul Chrystal
“Lost media” no longer! I finally got permission to upload “AL’S BRAIN,” an 11-minute educational 3-D film attraction which ran at the Orange County and Western Washington fairs, and hasn’t been seen publicly since 2009. You can watch the whole thing here: youtu.be/2xujU87ZHt4
August 31, 2026 at 4:19 PM
This is just evil!

Science sleuths discover thousands of antibodies from 15 vendors supported by doctored images on their websites.

www.nature.com/articles/d41...
August 26, 2026 at 12:43 AM
Reposted by Paul Chrystal
Biochemist Florence Seibert developed the Purified Protein Derivative (PPD) in the 1930s. Before her work, TB skin tests were inconsistent & unreliable. Her PPD formula was adopted as the international standard (1952) & remains in use for TB testing today.

Died #OTD in 1991. #WomenInSTEM
August 23, 2026 at 10:11 PM
Reposted by Paul Chrystal
If you have a new preprint or new publication within the field of developmental biology, cell biology, or mechanobiology, we more than welcome you to send them to us via DM to help them get the attention they deserve! We would love to support more ECRs!

#devbio #ecr #biology
Doris Roberts: We Support Each Other
ALT: Doris Roberts: We Support Each Other
static.klipy.com
August 18, 2026 at 5:12 PM
Reposted by Paul Chrystal
Nrl expression and promoter activity in developing cone photoreceptors https://www.biorxiv.org/content/10.64898/2026.08.06.743042v1
August 7, 2026 at 12:33 PM
How does one gene perform different functions in different tissues? Our new publication in @CommsBio sheds some light on the disparate roles of Usher Syndrome disease gene PCDH15.
www.nature.com/articles/s42...
August 7, 2026 at 6:50 AM
Congratulations to Ishmael Majeed from the Tropepe lab who successfully defended his Masters degree! Ishmael has been critical to developing new behavioural tests for visual function testing in our zebrafish mutants. Best of luck with your future graduate studies, Ishmael.
June 27, 2025 at 4:10 PM
Reposted by Paul Chrystal
If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)
June 13, 2025 at 2:30 PM
Thank you to @arvoinfo.bsky.social for the travel grant that got me to #ARVO2025. It was an amazing opportunity to hear about cutting-edge vision science and network with like-minded scientists. I will certainly be back next year in Denver!
May 23, 2025 at 5:08 PM
Thanks to everyone that came to chat at my poster today! Great way to end my first #ARVO2025 meeting. Looking forward to seeing you all again in Denver next year!
May 9, 2025 at 12:09 AM
If you are interested in learning about my research modelling Usher syndrome type 1F in zebrafish, "swim by" my poster tomorrow: A0097 #ARVO2025 #UsherSyndrome
May 7, 2025 at 10:09 PM
Reposted by Paul Chrystal
This year, we had ~3 dozen people at our #ARVO2025 zebrafish community gathering! So great to catch up with everyone!
May 6, 2025 at 5:06 AM
Incredible new work by @abimoye.bsky.social and colleagues who study microtubule associated proteins responsible for IRD. The iterative ultra expansion microscope images were breathtaking, and provide mechanistic insight into retinal diseases 👏
May 5, 2025 at 11:26 PM
Fascinating talk by @macdonaldlab.bsky.social at #ARVO2025 on the contribution of Müller glia to photoreceptor OS length in the high acuity zone of the retina. Is there anything MG can't do?
May 4, 2025 at 11:50 PM
Farewell Toronto and howdy Salt Lake City. Time to learn about the groundbreaking visual science that is happening across the globe at #ARVO2025
May 4, 2025 at 6:03 PM
Reposted by Paul Chrystal
Statement from APA re/autism and what the science really says: updates.apaservices.org/autism
Addressing Recent Misinformation About Autism
Recent statements from HHS Secretary Robert F. Kennedy Jr. contradict scientific consensus and potentially threaten essential research, services, and supports for autistic people.
updates.apaservices.org
April 20, 2025 at 12:40 PM
Reposted by Paul Chrystal
Free speech is no longer free in America.
March 20, 2025 at 10:15 AM