Varun Gadkari
@varun-gadkari.bsky.social
Assistant Professor | Department of Chemistry, University of Minnesota | Biological Mass Spectrometry | Views are my own | http://gadkari.chem.umn.edu
Reposted by Varun Gadkari
$1B is enough to pay each of those 30,000 people $33.3K for the next year.
Profit for 2025 & 2026 YTD?
$559,390,000,000
That pays those 30,000 people $18,646,333 for a year...
Or $372,926 per year, EACH for 50 years...
Or the entire 2024 NIH budget for 11.5 years...
@jeremymberg.bsky.social
Profit for 2025 & 2026 YTD?
$559,390,000,000
That pays those 30,000 people $18,646,333 for a year...
Or $372,926 per year, EACH for 50 years...
Or the entire 2024 NIH budget for 11.5 years...
@jeremymberg.bsky.social
September 9, 2026 at 7:23 PM
$1B is enough to pay each of those 30,000 people $33.3K for the next year.
Profit for 2025 & 2026 YTD?
$559,390,000,000
That pays those 30,000 people $18,646,333 for a year...
Or $372,926 per year, EACH for 50 years...
Or the entire 2024 NIH budget for 11.5 years...
@jeremymberg.bsky.social
Profit for 2025 & 2026 YTD?
$559,390,000,000
That pays those 30,000 people $18,646,333 for a year...
Or $372,926 per year, EACH for 50 years...
Or the entire 2024 NIH budget for 11.5 years...
@jeremymberg.bsky.social
Reposted by Varun Gadkari
Reposted by Varun Gadkari
Our department is hiring! We teach and do research with undergraduates exclusively. For a PUI, we have very good facilities and instrumentation (400 MHz NMR, six MS). Great colleagues and students — about 1/3 of majors go on to Ph.D. #chemsky @chemjobber.bsky.social
jobs.cofc.edu/postings/18244
jobs.cofc.edu/postings/18244
Assistant Professor of Chemistry and Biochemistry (organic)
Tenure-Track Assistant Professor in Organic Chemistry. The Department of Chemistry and Biochemistry at the College of Charleston invites applications for a tenure-track faculty position beginning in F...
jobs.cofc.edu
July 15, 2026 at 12:38 PM
Our department is hiring! We teach and do research with undergraduates exclusively. For a PUI, we have very good facilities and instrumentation (400 MHz NMR, six MS). Great colleagues and students — about 1/3 of majors go on to Ph.D. #chemsky @chemjobber.bsky.social
jobs.cofc.edu/postings/18244
jobs.cofc.edu/postings/18244
Reposted by Varun Gadkari
Check out our newest pub on CIU being used to predict the relationship between gas-phase protein unfolding and agonism in mAb variants!
Super cool read🤩🤩
Link: www.nature.com/articles/s41...
Super cool read🤩🤩
Link: www.nature.com/articles/s41...
Gas-phase unfolding assay rapidly predicts structure-function relationships in engineered antibodies with tuned flexibilities - Nature Communications
The agonistic activity of IgG2 antibodies depends, in part, on the flexibility of their hinge region, which is slow to measure in full-length antibodies. Here, the authors develop a rapid mass spectro...
www.nature.com
July 1, 2026 at 1:31 PM
Check out our newest pub on CIU being used to predict the relationship between gas-phase protein unfolding and agonism in mAb variants!
Super cool read🤩🤩
Link: www.nature.com/articles/s41...
Super cool read🤩🤩
Link: www.nature.com/articles/s41...
Reposted by Varun Gadkari
I'm thrilled to share that this January, I'll be joining @utaustinchemistry.bsky.social as an Assistant Professor! Dreams really do come true, you just have to keep showing up for them. Hook 'em horns 🤘
🧵👇
🧵👇
July 1, 2026 at 6:18 AM
I'm thrilled to share that this January, I'll be joining @utaustinchemistry.bsky.social as an Assistant Professor! Dreams really do come true, you just have to keep showing up for them. Hook 'em horns 🤘
🧵👇
🧵👇
Reposted by Varun Gadkari
The #ASMS Graduate Student Awards recognize graduate students (2nd year and beyond) whose academic achievements and current mass spectrometry research display a high level of excellence and distinction. Congratulations, all! #TeamMassSpec #ASMS2026
June 23, 2026 at 8:39 PM
The #ASMS Graduate Student Awards recognize graduate students (2nd year and beyond) whose academic achievements and current mass spectrometry research display a high level of excellence and distinction. Congratulations, all! #TeamMassSpec #ASMS2026
Reposted by Varun Gadkari
📢 NEW #ChemSciCovers
'Conformational landscapes resolved by ion mobility mass spectrometry reveal mechanisms of polyubiquitin-controlled phase separation' by Rebecca Beveridge et al.
🔗 doi.org/10.1039/D6SC...
Artwork created by Cara Jackson.
'Conformational landscapes resolved by ion mobility mass spectrometry reveal mechanisms of polyubiquitin-controlled phase separation' by Rebecca Beveridge et al.
🔗 doi.org/10.1039/D6SC...
Artwork created by Cara Jackson.
June 20, 2026 at 9:00 AM
📢 NEW #ChemSciCovers
'Conformational landscapes resolved by ion mobility mass spectrometry reveal mechanisms of polyubiquitin-controlled phase separation' by Rebecca Beveridge et al.
🔗 doi.org/10.1039/D6SC...
Artwork created by Cara Jackson.
'Conformational landscapes resolved by ion mobility mass spectrometry reveal mechanisms of polyubiquitin-controlled phase separation' by Rebecca Beveridge et al.
🔗 doi.org/10.1039/D6SC...
Artwork created by Cara Jackson.
Reposted by Varun Gadkari
The Kenagy and Millet Labs at UMN are hiring a postdoc to deploy mass spectral instruments on a new mobile lab focused on air composition, air quality, and environmental justice. Details at z.umn.edu/bdjg. Contact Hannah ([email protected]) & Dylan @dbm.bsky.social ([email protected]) with questions!
MobileLabPostdocAd-Concise
Postdoctoral Researcher The Kenagy Lab (Department of Chemistry; https://kenagy.chem.umn.edu/) and the Millet Lab (Department of Soil, Water, and Climate; https://atmoschem.umn.edu) at the University ...
z.umn.edu
June 16, 2026 at 8:41 PM
The Kenagy and Millet Labs at UMN are hiring a postdoc to deploy mass spectral instruments on a new mobile lab focused on air composition, air quality, and environmental justice. Details at z.umn.edu/bdjg. Contact Hannah ([email protected]) & Dylan @dbm.bsky.social ([email protected]) with questions!
Its #ASMS2026 week! Check out some great work being presented by trainees from the Gadkari group this week!
Monday
Gabby Blake: MOH 9:10
Rowan Matney: MP 144
Wednesday:
Pete Ledesma: WP 646
Eledon Beyene: WOA 4:10
Monday
Gabby Blake: MOH 9:10
Rowan Matney: MP 144
Wednesday:
Pete Ledesma: WP 646
Eledon Beyene: WOA 4:10
June 1, 2026 at 1:15 PM
Its #ASMS2026 week! Check out some great work being presented by trainees from the Gadkari group this week!
Monday
Gabby Blake: MOH 9:10
Rowan Matney: MP 144
Wednesday:
Pete Ledesma: WP 646
Eledon Beyene: WOA 4:10
Monday
Gabby Blake: MOH 9:10
Rowan Matney: MP 144
Wednesday:
Pete Ledesma: WP 646
Eledon Beyene: WOA 4:10
Reposted by Varun Gadkari
Congratulations to the 2026 ASMS Research Award recipients:
Kevin D. Clark, Daniel Petras, and Jared B. Shaw.
These awards support innovative research in mass spectrometry and are made possible through the support of Bruker, Thermo Fisher Scientific, and Waters Corporation.
Kevin D. Clark, Daniel Petras, and Jared B. Shaw.
These awards support innovative research in mass spectrometry and are made possible through the support of Bruker, Thermo Fisher Scientific, and Waters Corporation.
May 18, 2026 at 5:16 PM
Congratulations to the 2026 ASMS Research Award recipients:
Kevin D. Clark, Daniel Petras, and Jared B. Shaw.
These awards support innovative research in mass spectrometry and are made possible through the support of Bruker, Thermo Fisher Scientific, and Waters Corporation.
Kevin D. Clark, Daniel Petras, and Jared B. Shaw.
These awards support innovative research in mass spectrometry and are made possible through the support of Bruker, Thermo Fisher Scientific, and Waters Corporation.
Reposted by Varun Gadkari
New preprint from the group where we developed fluorescent and Halo tagged nanodiscs. All plasmids are available from @addgene.bsky.social if you are interested in trying them out!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
April 17, 2026 at 2:25 PM
New preprint from the group where we developed fluorescent and Halo tagged nanodiscs. All plasmids are available from @addgene.bsky.social if you are interested in trying them out!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Varun Gadkari
Science is good. We should fund it.
April 11, 2026 at 12:14 AM
Science is good. We should fund it.
Reposted by Varun Gadkari
(J Am Chem Soc) [ASAP] Ribosome Heterogeneity Revealed by Complex-Up Native Mass Spectrometry and Top-Down Proteomics: Journal of the American Chemical SocietyDOI: 10.1021/jacs.5c21227 #JAmChemSoc #MassSpecRSS
[ASAP] Ribosome Heterogeneity Revealed by Complex-Up Native Mass Spectrometry and Top-Down Proteomics
Journal of the American Chemical SocietyDOI: 10.1021/jacs.5c21227
dlvr.it
April 10, 2026 at 11:02 PM
(J Am Chem Soc) [ASAP] Ribosome Heterogeneity Revealed by Complex-Up Native Mass Spectrometry and Top-Down Proteomics: Journal of the American Chemical SocietyDOI: 10.1021/jacs.5c21227 #JAmChemSoc #MassSpecRSS
Reposted by Varun Gadkari
Watch Director Bhattacharya's performance at CPAC really got to me.
I chose to share some of my observations with him.
Hold on...
1/11
I chose to share some of my observations with him.
Hold on...
1/11
Here We Go Sherman Bell GIF
ALT: Here We Go Sherman Bell GIF
media.tenor.com
March 30, 2026 at 4:48 PM
Watch Director Bhattacharya's performance at CPAC really got to me.
I chose to share some of my observations with him.
Hold on...
1/11
I chose to share some of my observations with him.
Hold on...
1/11
Reposted by Varun Gadkari
Delta Air Lines is temporarily pulling back some special perks meant to ease travel for members of Congress amid the ongoing partial government shutdown.
Delta Air Lines suspends perks for Congress amid federal shutdown
The airline said it would keep open a special reservations line meant to help congressional members book travel.
bit.ly
March 25, 2026 at 8:39 PM
Delta Air Lines is temporarily pulling back some special perks meant to ease travel for members of Congress amid the ongoing partial government shutdown.
Reposted by Varun Gadkari
Excited to announce that I am the recipient of the 2026 ACS Division of Analytical Chemistry Arthur F. Findeis Award! Congrats to the other winners and honored to be in the great company of previous winners of this award!
acsanalytical.org/2026/03/05/2...
acsanalytical.org/2026/03/05/2...
2026 Analytical Division Award Winners
The ACS Division of Analytical Chemistry is pleased to announce the recipients of the 2026 Division Awards.
ACS Division of Analytical Chemistry Award in Electrochemistry
acsanalytical.org
March 6, 2026 at 6:42 PM
Excited to announce that I am the recipient of the 2026 ACS Division of Analytical Chemistry Arthur F. Findeis Award! Congrats to the other winners and honored to be in the great company of previous winners of this award!
acsanalytical.org/2026/03/05/2...
acsanalytical.org/2026/03/05/2...
Reposted by Varun Gadkari
Reposted by Varun Gadkari
That's right. Worse than Pointless
www.nytimes.com/2026/02/23/o...
www.nytimes.com/2026/02/23/o...
March 1, 2026 at 3:32 PM
That's right. Worse than Pointless
www.nytimes.com/2026/02/23/o...
www.nytimes.com/2026/02/23/o...
Modification of a QE-UHMR for soft-landing while maintaining full day-to-day function of the instrument for routine native MS work. Pretty cool.
(IJMS) Morphology Assessment Enabled by Room-Temperature Soft-Landing in Native MS: Publication date: Available online 16 February 2026
Source: International Journal of Mass Spectrometry
Author(s): Zihao Qi, Yu-Fu Lin, Sophie R. Harvey, Joshua D. Gilbert, Jared B. Shaw, Austin… #ijms #MassSpecRSS
Source: International Journal of Mass Spectrometry
Author(s): Zihao Qi, Yu-Fu Lin, Sophie R. Harvey, Joshua D. Gilbert, Jared B. Shaw, Austin… #ijms #MassSpecRSS
Morphology Assessment Enabled by Room-Temperature Soft-Landing in Native MS
Publication date: Available online 16 February 2026
Source: International Journal of Mass Spectrometry
Author(s): Zihao Qi, Yu-Fu Lin, Sophie R. Harvey, Joshua D. Gilbert, Jared B. Shaw, Austin Z. Salome, Chen Du, Marius M. Kostelic, Stella M. Lai, Andrew J. Arslanian, Joshua J. Coon, Vicki H. Wysocki
dlvr.it
February 18, 2026 at 2:00 AM
Modification of a QE-UHMR for soft-landing while maintaining full day-to-day function of the instrument for routine native MS work. Pretty cool.
Reposted by Varun Gadkari
Let me just make a few little adjustments to that title…
“How a scientist with a PhD in Geology and 25 years of experience is helping lead California’s earthquake work”
Way to devalue my experience.
“How a scientist with a PhD in Geology and 25 years of experience is helping lead California’s earthquake work”
Way to devalue my experience.
Wendy Bohon has built a TikTok following as an earthquake geologist. She helps lead earthquake work for the California Geological Survey.
How a TikToker and former actress is helping lead California’s earthquake work
Wendy Bohon has built a TikTok following as an earthquake geologist. She helps lead earthquake work for the California Geological Survey.
bit.ly
February 15, 2026 at 3:08 PM
Let me just make a few little adjustments to that title…
“How a scientist with a PhD in Geology and 25 years of experience is helping lead California’s earthquake work”
Way to devalue my experience.
“How a scientist with a PhD in Geology and 25 years of experience is helping lead California’s earthquake work”
Way to devalue my experience.
Reposted by Varun Gadkari
Liam is home now and we are grateful to @joaquincastrotx.bsky.social for traveling to Minneapolis with him and his dad.
Welcome home Liam ❤️❤️
Welcome home Liam ❤️❤️
February 1, 2026 at 5:40 PM
Liam is home now and we are grateful to @joaquincastrotx.bsky.social for traveling to Minneapolis with him and his dad.
Welcome home Liam ❤️❤️
Welcome home Liam ❤️❤️
Reposted by Varun Gadkari
Hundreds of people spelled out the distress signal "SOS" on Bde Maka Ska in Minneapolis on Friday, Jan. 30.
📷️ Provided by Jeff Schad
📷️ Provided by Jeff Schad
January 31, 2026 at 6:10 PM
Hundreds of people spelled out the distress signal "SOS" on Bde Maka Ska in Minneapolis on Friday, Jan. 30.
📷️ Provided by Jeff Schad
📷️ Provided by Jeff Schad
Reposted by Varun Gadkari
Quantitative Mapping of NHS Ester–Protein Reactivity Using Native Top-Down Mass Spectrometry #JASMS pubs.acs.org/doi/10.1021/...
Quantitative Mapping of NHS Ester–Protein Reactivity Using Native Top-Down Mass Spectrometry
Covalent ligands are widely used to label, probe, and modulate proteins, but peptide-centric readouts obscure how modifications colocalize on intact proteoforms. This can limit insight into ligand mechanism, modification stoichiometry, and the architecture of multisite protein conjugates. We present a general native top-down mass spectrometry workflow that quantifies electrophile reactivity directly on intact proteins. Using NHS esters as a model electrophile class, we apply a deconvolution framework to infer differential reactivity at primary amines across promiscuous, multisite modification patterns. The approach preserves full modification connectivity, avoids sample-preparation artifacts associated with denaturation and digestion, and should extend to electrophiles with unknown reactivity. Overall, this framework provides a general platform for designing covalent therapeutics, bioconjugates, and activity-based probes with proteoform-level resolution.
pubs.acs.org
January 29, 2026 at 9:42 AM
Quantitative Mapping of NHS Ester–Protein Reactivity Using Native Top-Down Mass Spectrometry #JASMS pubs.acs.org/doi/10.1021/...
Reposted by Varun Gadkari
The federal government is murdering our neighbors in broad daylight and carrying out a mission of terror against the Twin Cities. Schools and businesses are closed and people are staying home because they’re afraid of ICE. This is America in 2026: at war against its own people.
January 24, 2026 at 4:52 PM
The federal government is murdering our neighbors in broad daylight and carrying out a mission of terror against the Twin Cities. Schools and businesses are closed and people are staying home because they’re afraid of ICE. This is America in 2026: at war against its own people.
Reposted by Varun Gadkari
Man shot by federal agents has died, police chief says
www.startribune.com/ice-raids-mi...
www.startribune.com/ice-raids-mi...
Live: Man shot by federal agents in south Minneapolis this morning, witnesses say
A video appears to shows federal agents wrestling a man to the ground then shooting him.
www.startribune.com
January 24, 2026 at 4:37 PM
Man shot by federal agents has died, police chief says
www.startribune.com/ice-raids-mi...
www.startribune.com/ice-raids-mi...