Very excited to share the first preprint from my PhD with the community! This is also the first paper from the Plant Immunogenomics group with @galofir.bsky.social, so stay tuned for more!
www.biorxiv.org/content/10.6...
1/n 🧵

Happy birthday to Friedrich Miescher!

In 1869, Miescher became the first scientist to isolate what he called “nuclein” from the nuclei of white blood cells—the substance we now know as #DNA.

Read more in #GENETICS: buff.ly/0wReMtD

What drives the variation in mutation rates between seals and walruses, gulls and pelicans? Maybe selection counteracting the burden of deleterious mutations- or maybe it is a spandrel, a neutral byproduct of the diversification of development and life-history academic.oup.com/evolut/advan...

TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data.

@sholtodavid.bsky.social @johanduchene.bsky.social

reeserichardson.blog/2026/05/28/h...

Well done to everyone involved in this week's systems biology course; we cannot wait to see what you do with your new skills and the community you've created.

Looking for your own systems bioinformatics training? Why not start with our free on-demand related training: www.ebi.ac.uk/training/on-...

Heya science peeps, my first first-author paper is on Biorxiv! We show how transcriptome-wide expression variability in outbred animals responds massively to an environmental stressor and is underpinned by cryptic variability- (not just mean-) controlling alleles. www.biorxiv.org/content/10.6...

1/ DNA sequence models like Borzoi predict gene expression and variant effects across tissues — but how can someone adapt the model to a custom experiment? @drkbio.bsky.social, Johannes Linder and I propose a solution via parameter-efficient fine-tuning (PEFT).
www.biorxiv.org/content/10.1...

PhD position available for theoretical and statistical modeling in my joint @gevol.bsky.social project with @luisapallares.bsky.social on the evolution of transcriptional variability and its role in adaptation and evolutionary innovation.
See
job-portal.lmu.de/jobposting/6...

All info on this SBME satellite meeting on 'Origin, Maintenance, and Evolution of Biological Noise' is here: pallareslab.github.io/bionoise2025.... The recorded talks will be available soon! #BioNoise

Our SMBE Satellite Meeting on Biological Noise is only couple of days away! We will be streaming the talks on Zoom, in case you couldn't join us in person - Info about the zoom link and the program is here: pallareslab.github.io/bionoise2025...

🪰 🧬 Do you want to enhance your knowledge of Drosophila as a model organism? Then 'Drosophila genetics and genomics' might be the right course for you!

Apply now and join us in Heidelberg for lectures and practical sessions delivered by renowned experts 👉 s.embl.org/drg25-01-bl

#EMBODrosophila

Join us for our next Kipoi Seminar with with Pedro Tomaz da Silva @pedrotomazdasilva.bsky.social @gagneurlab.bsky.social @TU_Muenchen!
👉Nucleotide dependency analysis of DNA language models reveals genomic functional elements
📅Wed Feb 5, 5:30pm CET
🧬https://kipoi.org/seminar/
🦋kipoizoo.bsky

Deep learning with data beyond the genome: Our paper on active machine learning to model regulatory DNA is out today in Cell Systems.

With functional assays and DNA synthesis you can generate any training examples, not just genomic sequences. 🧵
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...