##TimeResolved
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drdominik.bsky.social
first draft: Sept 2021
now: published 🥳
merging CryoEM, crystallography & imaging wasn’t easy — but worth it.
grateful to everyone who made it happen.

#structuralbiology #CryoEM #timeresolved
natmethods.nature.com Nature Methods @natmethods.nature.com · May 5
A Review from experts in cryo-EM and X-ray crystallography describes the latest and greatest strategies for time-resolved structural biology.

www.nature.com/articles/s41...
May 6, 2025 at 11:10 AM
sasspectroscopy.bsky.social
New from Applied Spectroscopy!
Evaluation of the Raman Spectra of LEGO Blocks and Fluorescence Avoidance Using Pulsed Laser Excitation and Time-Resolved Detection
Read more: https://doi.org/10.1177/00037028251400397
#SAS #Spectroscopy #Raman #Fluorescence #Avoidance #TimeResolved
Abstract: In the first paper in this series, we proposed the use of a set of colored LEGO blocks as “standard” samples for the evaluation of fluorescence avoidance and mitigation schemes in Raman spectroscopy, as well as for use to evaluate the instruments’ performance on dark samples. In the second paper we described the spectra obtained on the same blocks from ten different handheld Raman instruments. We found that the combination of a series of colored blocks (white, yellow, red, and blue), and successively darker tone blocks (white, gray, and black) do challenge these instruments and shed light on the ways that their manufacturers have optimized these instruments in specific areas and for different purposes. In this paper we extend the work using an advanced Raman data collection technique: A fast-repetition-rate, short-pulse, laser with a single-photon avalanche photodiode (SPAD) array detector capable of providing a time-sequence output, commonly known as a “time-gating” or “time-resolved” approach. The results are evaluated and compared to those in the first two papers. In addition, X-ray fluorescence (XRF) spectra were also collected to confirm identifications of some of the blocks’ inorganic pigments, which were detected via their Raman spectra.
April 15, 2026 at 1:50 PM
actacrystd.iucr.org
An overview of current developments in serial crystallography is provided, emphasizing recent results in time-resolved crystallography, and discussing challenges and shortcomings. #SerialCrystallography #TimeResolved #StructuralDynamics doi.org/10.1107/S205...
August 6, 2024 at 1:31 PM
actacrystd.iucr.org
Alessandra Henkel et al.: A snapshot love story: what serial crystallography has done and will do for us ##SerialCrystallography##TimeResolved##StructuralDynamics... ##IUCrhttps://journals.iucr.org/paper?S2059798324005588
A snapshot love story: what serial crystallography has done and will do for us
This article gives an overview of current trends and challenges in serial crystallography, with a focus on results from time-resolved experiments.
journals.iucr.org
July 11, 2024 at 12:00 AM