Aku di apelin tiap hari sm abang🥰
Ini aku lg rebahan dibawah dia ikut2😭😭
Ini aku lg rebahan dibawah dia ikut2😭😭
September 13, 2024 at 11:46 AM
Aku di apelin tiap hari sm abang🥰
Ini aku lg rebahan dibawah dia ikut2😭😭
Ini aku lg rebahan dibawah dia ikut2😭😭
wow, that's pretty amazing
"Voluntary running for 4 weeks alleviated depression-like behaviors..." through a peptide hormone called apelin
"Voluntary running for 4 weeks alleviated depression-like behaviors..." through a peptide hormone called apelin
September 4, 2026 at 1:24 AM
wow, that's pretty amazing
"Voluntary running for 4 weeks alleviated depression-like behaviors..." through a peptide hormone called apelin
"Voluntary running for 4 weeks alleviated depression-like behaviors..." through a peptide hormone called apelin
Något som bekymrar mig med samtiden är att blodapelsin oftare och oftare kallas röd apelin.
March 30, 2024 at 1:42 PM
Något som bekymrar mig med samtiden är att blodapelsin oftare och oftare kallas röd apelin.
Altered circadian expression of Rev-erb-α & apelin/apelin receptor in aged lungs associates with dysregulated time-of-day control of pulmonary immune defenses against pneumococcal infections
www.cell.com/cell-reports...
@cp-cellreports.bsky.social
www.cell.com/cell-reports...
@cp-cellreports.bsky.social
February 4, 2025 at 6:53 PM
Altered circadian expression of Rev-erb-α & apelin/apelin receptor in aged lungs associates with dysregulated time-of-day control of pulmonary immune defenses against pneumococcal infections
www.cell.com/cell-reports...
@cp-cellreports.bsky.social
www.cell.com/cell-reports...
@cp-cellreports.bsky.social
Valuable structure-function study of this receptor. A little pet peeve: "a structure was not available when our experimental work was carried out, so we used AlphaFold2 [...]". Fine, but no comparative figures or analysis outside of saying "it was consistent", no AFm version, PDBs couldn't hurt...
Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor - Nature Communications
This study explores apelin receptor’s role in cardiovascular function, identifying residues critical for binding through genetic variants, AlphaFold2 modelling and base editing in cardiomyocytes. Co-c...
www.nature.com
December 27, 2024 at 4:46 PM
Valuable structure-function study of this receptor. A little pet peeve: "a structure was not available when our experimental work was carried out, so we used AlphaFold2 [...]". Fine, but no comparative figures or analysis outside of saying "it was consistent", no AFm version, PDBs couldn't hurt...
Thrilled to unveil the first-in-human use of #apelin in #hyponatremia at #ECE2025 in Copenhagen.
Endless gratitude to @christ-crain.bsky.social for championing bold research paths, and to @julierefardt.bsky.social and @fichapman.bsky.social, whose groundwork paved the way for this endeavor
Endless gratitude to @christ-crain.bsky.social for championing bold research paths, and to @julierefardt.bsky.social and @fichapman.bsky.social, whose groundwork paved the way for this endeavor
May 12, 2025 at 4:19 PM
Thrilled to unveil the first-in-human use of #apelin in #hyponatremia at #ECE2025 in Copenhagen.
Endless gratitude to @christ-crain.bsky.social for championing bold research paths, and to @julierefardt.bsky.social and @fichapman.bsky.social, whose groundwork paved the way for this endeavor
Endless gratitude to @christ-crain.bsky.social for championing bold research paths, and to @julierefardt.bsky.social and @fichapman.bsky.social, whose groundwork paved the way for this endeavor
Reader's Pick: Our most-accessed article in the past 30 days💫 : Apelin analog treatment reverses severe pulmonary arterial hypertension and right ventricular heart failure from Vu et al.: doi.org/10.1172/jci....
September 19, 2026 at 1:02 PM
Reader's Pick: Our most-accessed article in the past 30 days💫 : Apelin analog treatment reverses severe pulmonary arterial hypertension and right ventricular heart failure from Vu et al.: doi.org/10.1172/jci....
🧪 EvE Bio's biggest public data release (#4) yet!
1.4k Rx drugs screened for 24 new potential off-targets including adrenergic, apelin, muscarinic, dopamine, gastrin-releasing, orexin, 5-HT, neuromedin, opioid, prostaglandin, sphingosine, somatostatin & neuromedin receptors. evebio.org/data
1.4k Rx drugs screened for 24 new potential off-targets including adrenergic, apelin, muscarinic, dopamine, gastrin-releasing, orexin, 5-HT, neuromedin, opioid, prostaglandin, sphingosine, somatostatin & neuromedin receptors. evebio.org/data
May 19, 2025 at 3:01 PM
🧪 EvE Bio's biggest public data release (#4) yet!
1.4k Rx drugs screened for 24 new potential off-targets including adrenergic, apelin, muscarinic, dopamine, gastrin-releasing, orexin, 5-HT, neuromedin, opioid, prostaglandin, sphingosine, somatostatin & neuromedin receptors. evebio.org/data
1.4k Rx drugs screened for 24 new potential off-targets including adrenergic, apelin, muscarinic, dopamine, gastrin-releasing, orexin, 5-HT, neuromedin, opioid, prostaglandin, sphingosine, somatostatin & neuromedin receptors. evebio.org/data
Nicely done!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor - Nature Communications
This study explores apelin receptor’s role in cardiovascular function, identifying residues critical for binding through genetic variants, AlphaFold2 modelling and base editing in cardiomyocytes. Co-c...
www.nature.com
December 27, 2024 at 5:30 PM
Nicely done!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Christian Helker @unimarburg.bsky.social and co-workers show that apelin signaling acts as a molecular switch between endothelial and hematopoietic #stemcells.
link.springer.com/article/10.1...
Highlight by @labmonteiro.bsky.social @unibirmingham.bsky.social
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Highlight by @labmonteiro.bsky.social @unibirmingham.bsky.social
link.springer.com/article/10.1...
January 26, 2026 at 5:16 PM
Christian Helker @unimarburg.bsky.social and co-workers show that apelin signaling acts as a molecular switch between endothelial and hematopoietic #stemcells.
link.springer.com/article/10.1...
Highlight by @labmonteiro.bsky.social @unibirmingham.bsky.social
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Highlight by @labmonteiro.bsky.social @unibirmingham.bsky.social
link.springer.com/article/10.1...
Protective Role of Apelin in a Mouse Model of Post–Intensive Care Syndrome
@atscommunity.bsky.social #medsky
🔗 tinyurl.com/4mp87ant
@atscommunity.bsky.social #medsky
🔗 tinyurl.com/4mp87ant
March 24, 2026 at 5:54 PM
Protective Role of Apelin in a Mouse Model of Post–Intensive Care Syndrome
@atscommunity.bsky.social #medsky
🔗 tinyurl.com/4mp87ant
@atscommunity.bsky.social #medsky
🔗 tinyurl.com/4mp87ant
Scientists discover how exercising muscles communicate with the brain to fight depression
Scientists discover how exercising muscles communicate with the brain to fight depression
Physical exercise is known to improve mental health. A new study reveals that a muscle-released protein called apelin travels to the brain during exercise, promoting neuron growth and alleviating depression.
www.psypost.org
June 15, 2026 at 2:26 PM
Scientists discover how exercising muscles communicate with the brain to fight depression
Early apelin receptor activation attenuates elastase-induced emphysema and preserves endothelial apelin receptor signaling in mice https://www.biorxiv.org/content/10.64898/2026.05.12.724387v1
May 14, 2026 at 11:17 PM
Early apelin receptor activation attenuates elastase-induced emphysema and preserves endothelial apelin receptor signaling in mice https://www.biorxiv.org/content/10.64898/2026.05.12.724387v1
Physical activity is this thing you're recommended to do if you want to avoid/deal with depression or burnout. The why is less clear. This study pins it on a protein named apelin, which enhances neuron growth and improves mood. 🧪
Link: https://www.nature.com/articles/s41380-026-03651-y
Link: https://www.nature.com/articles/s41380-026-03651-y
June 16, 2026 at 3:07 PM
Physical activity is this thing you're recommended to do if you want to avoid/deal with depression or burnout. The why is less clear. This study pins it on a protein named apelin, which enhances neuron growth and improves mood. 🧪
Link: https://www.nature.com/articles/s41380-026-03651-y
Link: https://www.nature.com/articles/s41380-026-03651-y
Otw apelin kmu wkwkkk
July 13, 2024 at 1:47 PM
Otw apelin kmu wkwkkk
🔓Check out #OpenAccess research by John C. Vederas & co. from @ualberta.bsky.social in our latest issue exploring pharmaceutical potential of retro-inverso apelin peptides, part of our 5th Anniversary collection #medchem 🧪
Find in full on our website🔽
Find in full on our website🔽
Screening apelin analogues and a small molecule agonist as effective cardiovascular therapeutics against reperfusion injury
Ischemic reperfusion injury is a major global health threat, with the development of effective therapeutics still urgently needed. While both peptide therapeutics and small-molecule agonists have…
pubs.rsc.org
February 16, 2026 at 3:29 PM
🔓Check out #OpenAccess research by John C. Vederas & co. from @ualberta.bsky.social in our latest issue exploring pharmaceutical potential of retro-inverso apelin peptides, part of our 5th Anniversary collection #medchem 🧪
Find in full on our website🔽
Find in full on our website🔽
#StructuralBiology insights into #Genetic #GPCR variations identified in the UK 100,000 Genomes Project with differentiating effects on peptide (affected) vs. small molecule agonists (not affected) #pharmacology
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor - Nature Communications
This study explores apelin receptor’s role in cardiovascular function, identifying residues critical for binding through genetic variants, AlphaFold2 modelling and base editing in cardiomyocytes. Co-c...
www.nature.com
January 10, 2025 at 12:30 PM
#StructuralBiology insights into #Genetic #GPCR variations identified in the UK 100,000 Genomes Project with differentiating effects on peptide (affected) vs. small molecule agonists (not affected) #pharmacology
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Dynamic monomer-dimer transition in ligand-induced apelin receptor activation pubmed.ncbi.nlm.nih.gov/41932888/ #cryoem
April 4, 2026 at 10:19 AM
Dynamic monomer-dimer transition in ligand-induced apelin receptor activation pubmed.ncbi.nlm.nih.gov/41932888/ #cryoem
kakak cantik hai, ems mau ak apelin gk...?
June 11, 2024 at 12:47 PM
kakak cantik hai, ems mau ak apelin gk...?
Dynamic Monomer-Dimer Transition in Ligand-induced Apelin Receptor Activation https://www.biorxiv.org/content/10.1101/2025.02.19.639188v1
February 24, 2025 at 3:18 AM
Dynamic Monomer-Dimer Transition in Ligand-induced Apelin Receptor Activation https://www.biorxiv.org/content/10.1101/2025.02.19.639188v1
Dynamic Monomer-Dimer Transition in Ligand-induced Apelin Receptor Activation https://www.biorxiv.org/content/10.1101/2025.02.19.639188v1
February 24, 2025 at 3:18 AM
Dynamic Monomer-Dimer Transition in Ligand-induced Apelin Receptor Activation https://www.biorxiv.org/content/10.1101/2025.02.19.639188v1
I'M MAD BECAUSE YOU'RE BERY BERY PWETTY!!! mau aku apelin gk
June 13, 2024 at 12:14 PM
I'M MAD BECAUSE YOU'RE BERY BERY PWETTY!!! mau aku apelin gk
The authors included RRIDs in their in Cellular and Molecular Neurobiology paper! We value the author's support of reproducibility. #accelerateopenscience #reproducibility #STMpublishing
Apelin Receptor Signaling Protects GT1-7 GnRH Neurons Against Oxidative Stress In Vitro
Read the full paper: Apelin Receptor Signaling Protects GT1-7 GnRH Neurons Against Oxidative Stress In Vitro
doi.org
September 20, 2026 at 7:00 AM
The authors included RRIDs in their in Cellular and Molecular Neurobiology paper! We value the author's support of reproducibility. #accelerateopenscience #reproducibility #STMpublishing
17β-Estradiol Promotes Right Ventricle Angiogenesis via Estrogen Receptor α and Apelin Signaling https://www.biorxiv.org/content/10.64898/2025.12.11.693201v1
December 15, 2025 at 4:30 PM
17β-Estradiol Promotes Right Ventricle Angiogenesis via Estrogen Receptor α and Apelin Signaling https://www.biorxiv.org/content/10.64898/2025.12.11.693201v1