#EPI
A proposed UHRF1-MBD4 dialogue couples base excision repair of deamination-induced G:T mismatches with restoration of full DNA methylation fidelity at heterochromatin.
Details: https://www.maxapress.com/article/doi/10.48130/epi-0026-0009
#DNAMethylation #UHRF1 #MBD4 #BaseExcisionRepair

We are pleased at JBSD that Professor Dmitry O. Zharkov (Institute of Chemical Biology & Fundamental Medicine, SB RAS / Novosibirsk State University), a leading authority on DNA repair & DNA glycosylases, is continuing with us as an Editorial Board member. #JBSD #DNARepair #BaseExcisionRepair

Inactivation of🐭Ogg1, an essential #BaseExcisionRepair enzyme that repairs 8-oxoguanine ▶️

#ArterialStiffening without altered collagen fibril abundance

A very sophisticated #Matrisome related to #Aging-related #OxidativeDNADamage

#CardiovascRes 2024
academic.oup.com/cardiovascre...