Can safer MRI agents help hearts? Study finds Gd3+-dendrimer-amlodipine boosts cardiac imaging. #MRIContrast #CardiacImaging

Organized by the Department of Cardiovascular Sciences, Research Groups of Cardiology & Cardiovascular Imaging and Dynamics

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Introduction Right ventricle (RV) pseudoaneurysm is a substantially rare but fatal condition that should be diagnosed promptly to prevent severe complications, such as rupture and death. However, due to its nonspecific presentation, its diagnosis relies mainly on advanced imaging cardiac modalities. This report describes the successful management of a delayed and unusual presentation of RV pseudoaneurysm. Case presentation A 31-year-old white male patient with a history of pericardiectomy presented with chest pain and dyspnea, which worsened by exertion, and edema of the lower extremities, which had started several weeks ago and had been exacerbated over time. The initial evaluations with cardiac enzyme check, chest X-ray, and electrocardiogram were unremarkable, and the patient was planned to undergo a transthoracic echocardiogram (TTE). TTE revealed RV failure and increased RV diameter; a suspicious lesion in the RV apex was also detected, suggesting a pseudoaneurysm. Cardiac Computed Tomography (CTA) confirmed the diagnosis, and interventional treatment via an Amplatzer device was considered, which was rejected by the interventional cardiologist of the center due to the lack of experience and logistics for such intervention. Considering the patient’s condition deterioration, the patient was transferred to an operating room, and an open-heart surgery was performed to suture the ruptured RV myocardium. The pericardial effusion was removed. The histopathological evaluation of the sample confirmed the diagnosis. The post-surgical recovery and follow-up were uneventful. The graphical abstract is added below to illustrate the case and summarize it. Conclusion (Clinical key point) Right ventricle pseudoaneurysms can present with unusual symptoms and signs, and misdiagnosis is highly probable. Advanced imaging techniques after the initial echocardiogram might be necessary to confirm the diagnosis. Moreover, timely, appropriate, and wisely chosen treatment (interventional or surgical) can result in uneventful treatment and recovery. Graphical abstract

Cardiovascular Ultrasound Market growth is projected to reach 4.8 USD billion, at a 4.83% CAGR by driving industry size, share, top company analysis, segments research, trends and forecast report 2024...

AI-enhanced single-shot cine MRI produces superior image quality and provides ventricular measurements comparable to conventional cine MRI.

🫀 AI just changed the game in heart disease diagnosis. A new Nature Medicine case (June 2026) shows how ma… #Artificialintelligence #Cardiacimaging #Diagnosticacceleration #Hearttransplantation #Machinelearningcardiology