#CirculatingCalprotectin
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🤔 #CirculatingCalprotectin as a progonostic marker in Idiopathic Subglottic Stenosis
onlinelibrary.wiley.com/doi/10.1002/...
Serum S100A8/A9 Correlates to Surgery‐Free Interval in Idiopathic Subglottic Stenosis
This study investigates the potential of S100A8/A9 as a prognostic biomarker in Idiopathic Subglottic Stenosis (iSGS), a condition predominantly affecting women of northern European descent. Serum S1...
onlinelibrary.wiley.com
December 4, 2024 at 7:15 AM
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🤔New #CirculatingCalprotectin Publication: ''Calprotectin has the potential to be a mechanistically informed biomarker for ASCVD, independent of traditional and contemporary cardiovascular risk factors and biomarkers.''

jamanetwork.com/journals/jam...

#RheumSky #Calprotectin
Calprotectin and Atherosclerotic Cardiovascular Disease
This population-based cohort study examines the prospective association between circulating calprotectin and atherosclerotic cardiovascular disease as well as the mechanistic contributions of calprote...
jamanetwork.com
May 8, 2025 at 1:44 PM
drpaulalindner.bsky.social
Neutrophil activation in juvenile dermatomyositis: associations with muscle function and disease progression

#CirculatingCalprotectin and MPO-DNA as potential biomarkers for JDM muscle inflammation and functional outcomes.

#RheumSky

ped-rheum.biomedcentral.com/articles/10....
Neutrophil activation in juvenile dermatomyositis: associations with muscle function and disease progression - Pediatric Rheumatology
Background Juvenile dermatomyositis (JDM) is an inflammatory vasculopathy characterized by muscle weakness and systemic inflammation. This study aimed to investigate the clinical utility of neutrophil...
ped-rheum.biomedcentral.com
October 15, 2025 at 7:08 AM
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#CirculatingCalprotectin levels upon ICU admission as prognostic indicator for predicting the mortality in patients with sepsis-induced pulmonary ARDS during ICU hospitalization.

www.resmedjournal.com/article/S095...
Prognostic significance of serum Mrp 8/14 in acute respiratory distress syndrome induced by pulmonary and extrapulmonary sepsis: A retrospective controlled study
To date, it remains unclear whether serum Mrp 8/14 is differentially expressed in sepsis-induced ARDS patients of pulmonary and extrapulmonary origin during ICU hospitalization. This study investigate...
www.resmedjournal.com
November 25, 2025 at 1:27 PM
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🧐 #CirculatingCalprotectin in FMF: S100 proteins are key biomarkers to differentiate patients with class IV-V variants from those with class III variants

rmdopen.bmj.com/content/10/4...
Inflammatory biomarker analysis confirms reduced disease severity in heterozygous patients with familial Mediterranean fever
Introduction Familial Mediterranean fever (FMF) is a genetic disease leading to recurrent episodes of inflammation. Two pathogenic variants are required for classical disease, but the disease can occu...
rmdopen.bmj.com
December 4, 2024 at 8:34 AM
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🧠 New study in #SLE patients links elevated #CirculatingCalprotectin to cognitive impairment. Higher levels correlated with worse performance across domains—and tracked with changes in cognitive status over 1 year.

#RheumSky

acrjournals.onlinelibrary.wiley.com/doi/10.1002/...
Association of Elevated Serum S100A8/A9 Levels and Cognitive Impairment in Systemic Lupus Erythematosus Patients
Objectives Cognitive impairment (CI) is common in patients with Systemic Lupus Erythematosus (SLE). Despite its prevalence, the immune mechanisms are not well understood. We previously reported elev...
acrjournals.onlinelibrary.wiley.com
May 22, 2025 at 7:45 AM
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🗣️New study showing the correlation of #CirculatingCalprotectin and disease activity in PsA.

''Evaluation of Serum Calprotectin Levels and Their Relationship with Disease Activity in Psoriatic Arthritis and Axial Spondyloarthritis''

#Rheumatology #RheumSky #PsA

www.mdpi.com/1648-9144/62...
March 3, 2026 at 1:19 PM
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👉Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein

#RheumSky #CirculatingCalprotectin

rmdopen.bmj.com/content/11/3...
Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein
Objectives C reactive protein (CRP) is frequently normal in psoriatic arthritis (PsA) despite active disease, complicating inflammation assessment. This study aimed to evaluate alternative biomarkers ...
rmdopen.bmj.com
October 6, 2025 at 7:32 AM
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Happy to share the newest Gentian GCAL newsletter. Tune in for updates and insights. #CirculatingCalprotectin #RheumSky

www.linkedin.com/pulse/circul...
Circulating calprotectin - the power to assess inflammation 2/2025
As we move into the second half of 2025, we are pleased to provide an update on GCAL® - our assay for circulating calprotectin - and to highlight recent research and studies that continue to expand kn...
www.linkedin.com
September 9, 2025 at 9:53 AM
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Fresh off the press, this review takes a deep look into #CirculatingCalprotectin in GCA.

www.frontiersin.org/journals/imm...

#RheumSky
Frontiers | The role of calprotectin in giant cell arteritis - from pathophysiology to possible clinical applications
Giant cell arteritis (GCA) is an immune-mediated vasculitis predominantly affecting individuals aged 50 years and older, with clinical manifestations often o...
www.frontiersin.org
September 2, 2025 at 12:27 PM
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👏 SelectScience editorial on #CirculatingCalprotectin received an award for the best ''Clinical Diagnostics Editorial Article of the Year'' at #ADLM this year.

#RheumSky

www.selectscience.net/article/how-...
How serum calprotectin is transforming rheumatic disease diagnosis
Discover how serum calprotectin is advancing the diagnosis, monitoring, and treatment of rheumatic diseases. Learn about its role in predicting flare-ups and guiding personalized care.
www.selectscience.net
August 4, 2025 at 8:19 AM
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''Serum S100A8/A9 concentration at ICU admission is a significant predictor of 28-day mortality risk in sepsis patients''

#CirculatingCalprotectin #Sepsis

www.frontiersin.org/journals/cel...
Frontiers | Assessment of S100A8/A9 and resistin as predictive biomarkers for mortality in critically ill patients with sepsis
IntroductionSepsis is associated with high mortality. Early intervention is crucial to reducing sepsis-related mortality. This study aims to assess the clini...
www.frontiersin.org
July 1, 2025 at 12:40 PM
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Review: Biomarkers in juvenile idiopathic arthritis: towards precision diagnosis and personalized therapy?

#CirculatingCalprotectin as promising tool for monitoring and prognosis in JIA by its ability to predict flares and subclinical inflammation.

#RheumSky

journals.lww.com/co-rheumatol...
Biomarkers in juvenile idiopathic arthritis: towards... : Current Opinion in Rheumatology
years, research has increasingly focused on the identification and validation of biomarkers to enhance diagnostic precision, predict disease course, and guide therapeutic decisions. Recent findings ...
journals.lww.com
June 24, 2025 at 12:15 PM
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🗣️ #CirculatingCalprotectin identified as a crucial biomarker and potential therapeutic target of fulminant myocarditis.

High levels associated with longer hospital stays and higher risks of adverse outcomes.

#CardioSky

www.sciencedirect.com/science/arti...
Plasma proteomics identifies S100A8/A9 as a novel biomarker and therapeutic target for fulminant myocarditis
Fulminant myocarditis (FM) is a lethal inflammatory myocardial disease characterized by rapid progression and poor prognosis. Investigating plasma pro…
www.sciencedirect.com
June 10, 2025 at 11:52 AM
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🧐 #CirculatingCalprotectin availability is increasing in several European countries.

According to the 2021 EULAR/ACR recommendations, the clinical examination of systemic inflammation for IL-1 diseases should now also include calprotectin if accessible.

ped-rheum.biomedcentral.com/articles/10....
Diagnosis, management, and monitoring of interleukin-1 mediated diseases in Central and Eastern Europe: real-world data - Pediatric Rheumatology
Background Global healthcare disparities, stemming from organizational differences in healthcare systems, lead to variable availability and funding, resulting in a gap between recommended and implemen...
ped-rheum.biomedcentral.com
June 5, 2025 at 12:28 PM
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🧐 #CirculatingCalprotectin in Polycystic ovary syndrome reported to provide insights into the inflammatory processes.

www.nature.com/articles/s41...
Evaluation of serum calprotectin levels in patients with polycystic ovary syndrome - Scientific Reports
Scientific Reports - Evaluation of serum calprotectin levels in patients with polycystic ovary syndrome
www.nature.com
April 29, 2025 at 12:24 PM
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#StillsDisease diagnosis is often delayed.
#CirculatingCalprotectin can be an important part in early differentiation from infections and other inflammatory causes of presented symptoms. (Recommended by PReS/EULAR guidelines.)

#RheumaSky #EULAR #PReS
March 28, 2025 at 9:32 AM
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Happy to share the first Gentian GCAL newsletter of 2025. Tune in for updates and insights. #CirculatingCalprotectin

www.linkedin.com/pulse/circul...
Circulating calprotectin - the power to assess inflammation 1/2025
We are excited to welcome you to the first newsletter of 2025! As we look back on a transformative 2024, it’s clear that the awareness of the clinical impact of circulating calprotectin continues to g...
www.linkedin.com
March 26, 2025 at 7:56 AM
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Highlights from Breakout session in vasculitis in paediatric rheumatology. Including results of #Calprotectin (S100A8/A9) in IgA vasculitis, where elevated levels were significantly associated with active disease.

academic.oup.com/rheumatology...

#ReuhmaSky #CirculatingCalprotectin
Highlights from the breakout session: vasculitis in paediatric rheumatology
Abstract. The 21st International Vasculitis Workshop, held in Barcelona, Spain, from April 7 to 10, 2024, highlighted advances in pediatric vasculitis, foc
academic.oup.com
March 14, 2025 at 12:52 PM
drpaulalindner.bsky.social
#CirculatingCalprotectin predicting mortality in sepsis-induced ARDS patients during ICU hospitalization

''Prognostic value of serum Mrp 8/14 in sepsis-induced acute respiratory distress syndrome patients: a retrospective cohort study''
peerj.com/articles/187...

#ICU #sepsis #biomarker #S100A8/A9
Prognostic value of serum Mrp 8/14 in sepsis-induced acute respiratory distress syndrome patients: a retrospective cohort study
Background Mrp 8/14 is abundantly secreted by activated neutrophils during infection and inflammation. However, its prognostic value in acute respiratory distress dyndrome (ARDS) induced by sepsis is ...
peerj.com
January 6, 2025 at 7:53 AM
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𝗨𝗻𝗹𝗼𝗰𝗸𝗶𝗻𝗴 𝗶𝗻𝘀𝗶𝗴𝗵𝘁𝘀 𝗶𝗻𝘁𝗼 #𝗥𝗵𝗲𝘂𝗺𝗮𝘁𝗶𝗰𝗗𝗶𝘀𝗲𝗮𝘀𝗲𝘀 𝘄𝗶𝘁𝗵 #CirculatingCalprotectin 𝘁𝗲𝘀𝘁𝗶𝗻𝗴, 𝗮𝘀 𝘁𝗵𝗶𝘀 𝗯𝗶𝗼𝗺𝗮𝗿𝗸𝗲𝗿 𝘁𝗿𝗮𝗻𝘀𝗳𝗼𝗿𝗺𝘀 𝘁𝗵𝗲 𝗹𝗮𝗻𝗱𝘀𝗰𝗮𝗽𝗲 𝗼𝗳 𝗿𝗵𝗲𝘂𝗺𝗮𝘁𝗶𝗰 𝗱𝗶𝘀𝗲𝗮𝘀𝗲 𝗺𝗮𝗻𝗮𝗴𝗲𝗺𝗲𝗻𝘁.

www.gentian.com/news/circula...

#RheumSky
Circulating calprotectin in rheumatic diseases
Calprotectin in serum and plasma has been described as valuable biomarker in several chronic inflammatory conditions, including multiple rheumatic conditions
www.gentian.com
December 19, 2024 at 8:58 AM
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#CirculatingCalprotectin
as one potential biomarker in OSA signature.

KL‑6, ET‑1 and S100A9 levels in patients with idiopathic pulmonary fibrosis and obstructive sleep apnea

pmc.ncbi.nlm.nih.gov/articles/PMC...
KL‑6, ET‑1 and S100A9 levels in patients with idiopathic pulmonary fibrosis and obstructive sleep apnea
Obstructive sleep apnea (OSA) and idiopathic pulmonary fibrosis (IPF) frequently coexist. Elevated levels of Krebs von den Lungen-6 (KL-6), endothelin-1 (ET-1) and S100 calcium-binding protein A9 (S10...
pmc.ncbi.nlm.nih.gov
December 10, 2024 at 1:37 PM
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From our FAQ series for
#CirculatingCalprotectin

www.gentian.com/news/circula...
FAQ: What role has circulating calprotectin in vasculitis?
The use of serum or plasma calprotectin as inflammation and activity biomarker in different forms of vasculitis
www.gentian.com
November 29, 2024 at 10:27 AM
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From our FAQ series for #CirculatingCalprotectin

www.gentian.com/news/plasma-...
FAQ: What is the value of circulating calprotectin in JIA & Still’s disease?
The neutrophilic protein calprotectin has been described as valuable biomarker in several rheumatic conditions, including rheumatoid arthritis (RA) and JIA
www.gentian.com
November 21, 2024 at 2:12 PM
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Excited to share our newsletter covering the latest news, developments, and updates in #CirculatingCalprotectin
Circulating calprotectin - the power to assess inflammation 3/2024 linkedin.com/pulse/circul...
Circulating calprotectin - the power to assess inflammation 3/2024
We are witnessing a growing global demand for circulating calprotectin, underscoring its recognition as a valuable biomarker in detection and assessment of inflammation and inflammatory response to in...
linkedin.com
November 11, 2024 at 12:04 PM