#ClinicalReview
LightNews LightNews
castltrastondrs.medsky.network
#Medsky🧪 #IDsky #immunosky #Microsky #publichealth The #clinicalReview @natrevgastrohep.nature.com delves into the profound impact of diet on shaping the #gutmicrobiome & host immunity .
The gut microbiome connects nutrition and human health
Nature Reviews Gastroenterology & Hepatology - In this Review, Sanz and colleagues discuss how diet shapes the gut microbiome, the role of diet–microbiome interactions on the immune,...
www.nature.com
August 16, 2025 at 6:27 AM
castltrastondrs.medsky.network
#Medsky🧪 #immunosky #oncosky #clinicalreview This review summarises the latest findings regarding the links between #cancergenetic abnormalities & #immunosuppression causing clinical resistance to #immunotherapy.

www.science.org/doi/10.1126/... @science.org
pdf

www.science.org/doi/epdf/10....
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression
Understanding the impacts of genetic abnormalities on immune responses to tumors can inform immunogenomic-based precision medicine.
www.science.org
March 31, 2025 at 7:07 PM
ipro1984.bsky.social
Calling all board-certified physicians – we need you! 🫵

Learn more by visiting ipro.org/clinical-rev... or by calling (888) 404-6285.

#ClinicalReview #PatientCare #Physicians
September 22, 2026 at 6:02 PM
castltrastondrs.medsky.network
ImmunoSky #Immunology #Clinicalreview summarized recent advances in #Bcell targeted therapies in #autoimmunedisease of the #centralnervoussystem including #multiplesclerosis , #neuromyelitisopticaspectrumdisorder and MOG antibodies associated diseases (MOGAD)…

www.frontiersin.org/articles/10....
Editorial: Next generation B cell targeting therapies in autoimmune diseases
Editorial: Next generation B cell targeting therapies in autoimmune diseases
www.frontiersin.org
November 10, 2023 at 3:17 PM
castltrastondrs.medsky.network
Cognitive dysfunctions in the course of #SARSCoV2 🦠 infection, including #NeuroCOVID, frontal syndrome and cytokine storm ( #ClinicalReview )
www.spandidos-publications.com/10.3892/br.2...
Cognitive dysfunctions in the course of SARS‑CoV‑2 virus infection, including NeuroCOVID, frontal syndrome and cytokine storm (Review)
During the coronavirus disease 2019 (COVID‑19) pandemic, cognitive impairment of varying degrees of severity began to be observed in a significant percentage of patients. The present study discussed t...
www.spandidos-publications.com
July 5, 2024 at 3:47 PM
castltrastondrs.medsky.network
#MedSky🧪#IDSky #Publichealth #Publichealth #Clinicalreview The Role of #ACE2 in #NeurologicalDisorders: From Underlying Mechanisms to the Neurological Impact of #LongCovid

mdpi-res.com/d_attachment...

www.mdpi.com/1422-0067/25...
The role of ACE2 in neurological diseases and its impact on the nervous system under SARS-CoV-2 infection. (Created with Biorender.com).
September 15, 2024 at 11:59 AM
castltrastondrs.medsky.network
MedSky🧪#IDSky #viralimmunology The infographic that tell 1000 words & not an organ to spare by #COVID19 collateral damages #MaskUp😷 & #GetBoosted This comprehensive #clinicalreview of #COVID19 from host extracellular to systemic effects of #SARSCoV2 infection!
Part 2
www.nature.com/articles/s41...
A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SA...
European Journal of Human Genetics - A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection
www.nature.com
November 11, 2023 at 2:02 PM
castltrastondrs.medsky.network
#MedSky🧪 #IDSky #PedSky #ImmunoSky #EpiSky #Clinicalreview the current Clinical #epidemiology, symptoms, diagnostic approaches, and treatments for pediatric #PASC / #LongCovidKid / #NeuroCovid in 🇺🇸
www.sciencedirect.com/science/arti...
Post-Acute sequelae of COVID-19 in pediatric patients within the United States: A Scoping Review
A subset of children and adolescents experience recurrent or persistent symptoms following SARS-CoV-2 infection, known as post-acute sequelae of COVID…
www.sciencedirect.com
October 2, 2024 at 5:53 AM
castltrastondrs.medsky.network
#MedSky🧪#IDSky #Publichealth This #Clinicalreview the current state of knowledge regarding the #biology & #pathophysiology of #longCOVID focusing on how the proposed mechanisms explain the #physiology of the syndrome & the implementation of a broad #experimentalmedicine

www.cell.com/cell/fulltex...
Mechanisms of long COVID and the path toward therapeutics
Known under competing terms and definitions such as post-COVID-19 condition, post-COVID-19 conditions, post-acute sequelae of SARS-CoV-2 (PASC), post-COVID-19 syndrome, post-COVID-19, or long COVID, t...
www.cell.com
October 3, 2024 at 5:05 PM
castltrastondrs.medsky.network
#MedSky🧪#IDSky #Immunopharmacology #publichealth #Clinicalreview Summarize the major #Drugsdiscovery approaches, preclinical #antiviral evaluation models, representative virus-targeting , host-targeting therapeutic options
June 4, 2024 at 11:42 AM
castltrastondrs.medsky.network
In this #ClinicalReview define CVAD & its major forms that are encountered in LC describe possible CVAD aetiologies , discuss how CVAD, as a componen of LC can be diagnosed & managed. Outline directions for future research to discover more efficient ways to cope w this prevalent & long-lasting dx.
PDF
January 3, 2024 at 6:44 AM
castltrastondrs.medsky.network
#Medsky🧪 #publichealth #Clinicalreview @jama.com Recent advances in the diagnosis and treatment of #irondeficiency highlight its prevalence & health impact beyond #anemia.
edhub.ama-assn.org/jn-learning/...
Iron Deficiency in Adults: Advances in Diagnosis and Treatment
Absolute iron deficiency with or without anemia affects about 2 billion people worldwide and 14% of adults in the US. Discover causes, diagnosis, and best practices for oral and intravenous iron therapy in adults in this discussion between Michael Auerbach, MD, from Georgetown University School of Medicine, and JAMA Associate Editor Margaret Wheeler, MD.
edhub.ama-assn.org
March 30, 2026 at 5:19 PM
castltrastondrs.medsky.network
#MedSky🧪#IDSky #ImmunoOncology in this #Clinicalreview present the summarised & overview of the various biological alterations induced by #SARSCoV2 infection and its proteins with respect to cancer hallmarks

biosignaling.biomedcentral.com/articles/10....
Oncogenic potential of SARS-CoV-2—targeting hallmarks of cancer pathways - Cell Communication and Signaling
The 2019 outbreak of SARS-CoV-2 has caused a major worldwide health crisis with high rates of morbidity and death. Interestingly, it has also been linked to cancer, which begs the issue of whether it ...
biosignaling.biomedcentral.com
September 27, 2024 at 12:54 PM
ngmjournal.bsky.social
🆕🔥Central & peripheral #Neuromodulators in #FD & #Gastroparesis: Symptom-Based #ClinicalReview‼️
🎯A pragmatic, symptom-oriented & mechanism-based approach facilitate individualized treatment selection & optimize clinical outcomes
👉 onlinelibrary.wiley.com/doi/10.1111/...
#ANMS #ESNM
Key Points • First-line therapies for functional dyspepsia, including proton pump inhibitors and Helicobacter pylori eradication, provide limited symptom relief in a substantial proportion of patients. • Functional dyspepsia and gastroparesis share overlapping symptoms but differ in predominant pathophysiological mechanisms, requiring tailored therapeutic strategies. • Predominantly central neuromodulators are most appropriate for epigastric pain syndrome, whereas predominantly peripheral neuromodulators are better suited for postprandial distress syndrome and gastroparesis-related nausea and vomiting. • A pragmatic, symptom-oriented, and mechanism-based approach may facilitate individualized treatment selection and optimize clinical outcomes.
March 4, 2026 at 2:41 PM
msklibrary.bsky.social
Featured today by @MSKLibrary: Ten years of experience with ruxolitinib since approval for polycythemia vera: A review of clinical efficacy and safety
#Ruxolitinib #PolycythemiaVera #ClinicalReview #hematology
@MDmasarova @RaajitRampal @doctorpemm

dx.doi.org/10.1002/cncr...
Ten years of experience with ruxolitinib since approval for polycythemia vera: A review of clinical efficacy and safety
This study reviews the safety and efficacy profile of the oral JAK1/2 inhibitor ruxolitinib from the decade since its 2014 Food and Drug Administration approval for patients with polycythemia vera wh....
dx.doi.org
January 7, 2025 at 4:16 PM
castltrastondrs.medsky.network
#Medsky🧪#IDsky #immunosky #Publichealth #clinicalreview Interesting study .Does #SARSCoV2 Possess “Allergen-Like” Epitopes?

www.preprints.org/manuscript/2...
igure 1. The function that allergen-specific IgG4 plays in exposure to allergens. (A) Acute allergen exposure lay cause IgE-mediated histamine-induced hypersensitivity reactions through the high-affinity receptor FceRI. 3) Long-term exposure to allergens may cause the development of IgG4, which then binds to the allergen. IgG4 len binds to the inhibitory receptor FcyRIlb located on mast cells and basophils, thus limiting hypersensitive actions and promoting allergy tolerance. Source: [19]. This is an open-access article and distributed under the rms of the Creative Commons Attribution 4.0 International (CC BY 4.0), which permits unrestricted use, istribution, and reproduction in any medium, provided the original work is properly cited.
March 9, 2025 at 3:19 PM
ipro1984.bsky.social
Calling all board-certified physicians – we need you! 🫵

Learn more by visiting ipro.org/clinical-reviewers/ or by calling (888) 404-6285.

#ClinicalReview #PatientCare #Physicians
September 15, 2026 at 12:44 PM
ipro1984.bsky.social
Calling all board-certified physicians – we need you! 🫵

Learn more by visiting ipro.org/clinical-rev... or by calling (888) 404-6285.

#ClinicalReview #PatientCare #Physicians
September 8, 2026 at 6:40 PM
ipro1984.bsky.social
Calling all board-certified physicians – we need you! 🫵

Learn more by visiting ipro.org/clinical-rev... or by calling (888) 404-6285.

#ClinicalReview #PatientCare #Physicians
September 4, 2026 at 4:02 PM
ipro1984.bsky.social
Calling all board-certified physicians – we need you! 🫵

Learn more by visiting ipro.org/clinical-reviewers/ or by calling (888) 404-6285.

#ClinicalReview #PatientCare #Physicians
August 25, 2026 at 12:15 PM
ipro1984.bsky.social
Calling all board-certified physicians – we need you! 🫵

Learn more by visiting ipro.org/clinical-reviewers/ or by calling (888) 404-6285.

#ClinicalReview #PatientCare #Physicians
August 21, 2026 at 4:02 PM
ipro1984.bsky.social
We're looking for board-certified physicians with at least five years of active clinical experience who currently work at least 20 hours per month on direct patient care.🏥

Become a clinical reviewer today! Learn more by visiting ipro.org/clinical-rev... or calling 888-404-6285.

#ClinicalReview
August 13, 2026 at 2:01 PM
ipro1984.bsky.social
We're looking for board-certified physicians with at least 5 years of active clinical experience who currently work at least 20 hours per month on direct patient care. 🏥

Learn more by visiting ipro.org/clinical-rev... or calling 888-404-6285.

#Veterans #Healthcare #ClinicalReview
August 10, 2026 at 1:21 PM
ipro1984.bsky.social
We're looking for board-certified physicians with at least 5 years of active clinical experience who currently work at least 20 hours per month on direct patient care. 🏥

Learn more by visiting ipro.org/clinical-rev... or calling 888-404-6285.

#Veterans #Healthcare #ClinicalReview
August 4, 2026 at 3:06 PM
castltrastondrs.medsky.network
#MedSky🧪#Neuropharmacology #psychiatricdrugs #Clinicalreview on medicines containing #finasteride & #dutasteride following concerns regarding suicidal thoughts & behaviours. @EMA_News

www.ema.europa.eu/en/news/meet...
Inforgraphic
October 4, 2024 at 7:58 PM