Curvularia, a cosmopolitan fungal genus, occupies various ecological niches, but displays a pronounced tendency to colonise the leaves of plants. In this study, several fungal isolates with similar ch...

This study investigated the effects of fungal (Penicillium chrysogenum, Thielavia basicola, Curvularia hawaiiensis) and bacterial (Sphingomonas aquatilis, Bacillus licheniformis, Exiguobacterium auran...

AbstractBackground. Invasive fungal infections (IFIs) are uncommon infections that account for approximately 27.2/100,000 cases per year in the United Stat

Iron is indispensable for the vast majority of organisms, and iron homeostasis plays a pivotal role in both the physiology and pathogenesis of fungal pathogens. However, the underlying mechanisms by.....

Purpose: The aim of this study was to evaluate the activity of photoactivated 0.1% rose bengal (RB) for in vitro growth inhibition of the most prevalent fungi isolates in infectious keratitis. Methods: Eight corneal clinical isolates were included in the experiments: Fusarium solani complex, Purpureocillium lilacinum, Candida albicans, Candida parapsilosis complex, Exophiala oligosperma, Scedosporium apiospermum complex, Aspergillus niger complex, and Curvularia geniculata. Microorganisms, previously identified by phenotypical methods, were grown and incubated at specific conditions and prepared in suspension for concentration adjustments. The following groups were evaluated in triplicate: group I, no treatment; group II, treated with RB and exposed to the dark for 30 minutes; group III, exposed to green-light light-emitting diode 7.2 mW for 30 minutes (photodynamic therapy [PDT]); and group IV, treated with RB and PDT (RB-PDT). The final work concentration was 104 cells per mL. The RB-PDT was combined with Amphotericin B (AmphoB) to target isolates that were not inhibited by RB-PDT alone. Plates were incubated at specific conditions and photographed after growth for pixel analyses. Results: The growth was inhibited after RB-PDT for F. solani complex, P. lilacinum, C. albicans, C. parapsilosis complex, and E. oligosperma, and not inhibited for S. apiospermum complex, A. niger complex, and C. geniculata, even though combining RB-PDT with AmphoB. Conclusions: RB-PDT presented good activity against five of the tested microorganisms. For the first time, we demonstrated that RB-PDT could inhibit growth of P. lilacinum, C. parapsilosis complex, E. oligosperma, and not inhibit S. apiospermum, A. niger complex, and C. geniculata, even when combined with AmphoB.

Published in World journal of microbiology & biotechnology

This study provides the first comprehensive evaluation of the efficacy of three Trichoderma species (Trichoderma longibrachiatum, Trichoderma harzianum, and ...

AbstractBackground. Curvularia species are dematiaceous environmental molds that rarely cause disease in humans. Infections may be superficial or invasive

(described by Boedijn in 1933) Taxonomic Classification Kingdom: Fungi Phylum: Ascomycota Class: Euascomycetes Order: Pleosporales Family: Pleosporaceae Genus: Curvularia Description and Natural Habit...