#DNAMethylation-based
LightNews LightNews
haoyin.bsky.social
Accelerated #EpigeneticAging of #IdiopathicPulmonaryFibrosis🫁

6 #DNAMethylation-based #EpigeneticClocks
Horvath's Clock
Hannum's Clock
AltumAge
PhenoAge
GrimAge
DunedinPAC

IPF🫁(n=10) are "Older" than control🫁(n=6)😎

#AJPLung 2025 @kaminskimed.bsky.social
journals.physiology.org/doi/abs/10.1...
February 21, 2025 at 8:22 PM
jsantoyo.bsky.social
Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA. #cfDNA #DNAmethylation #MethodBenchmarking #GenomeBiology #Genomics 🧬
genomebiology.biomedcentral.com/articles/10....
Systematic evaluation of methylation-based cell type deconvolution methods for plasma cell-free DNA - Genome Biology
Background Plasma cell-free DNA (cfDNA) is derived from cellular death in various tissues. Investigating the tissue origin of cfDNA through cell type deconvolution, we can detect changes in tissue hom...
genomebiology.biomedcentral.com
December 19, 2024 at 8:29 PM
biorxiv-bioinfo.bsky.social
Islands of Signal and Transcriptomic Sequencing: A Foundation Model for Mutation and Lineage Prediction based on DNAMethylation and RNA-seq https://www.biorxiv.org/content/10.64898/2025.12.01.691534v1
December 2, 2025 at 10:46 PM
castltrastondrs.medsky.network
#DNAMethylation - Based #EpigeneticClocks & Their Role in Aging.
🔑 highlights
-DNA methylation-based epigenetic clocks are established tools for estimating biological age by measuring methylation at specific CpG sites with widely used models incl the Horvath clock, Hannum clock, PhenoAge & GrimAge
December 9, 2025 at 7:42 AM
epicypher.bsky.social
🧪🧬April is a big month at EpiCypher—we’re launching two new CUT&RUN-based DNA methylation profiling technologies! 🚀
Get a sneak peek at #KSEpigenetics25 during @ellen-epi.bsky.social talk on Wed, April 2 (8–11AM). Can’t wait to share what’s coming!
#epigenetics #CUTandRUN #DNAmethylation
April is a big month at EpiCypher—we’re launching two new CUT&RUN-based DNA methylation profiling technologies! Get a sneak peek at #KSEpigenetics25 during Ellen Weinzapfel's talk on Wed, April 2 (8–11AM). Can’t wait to share what’s coming!
March 28, 2025 at 3:18 PM
aging-us.bsky.social
#AgingResearch:
A new #research paper was recently #published in Volume 17, Issue 1, entitled "Characterization of DNA methylation clock algorithms applied to diverse tissue types."

#PressRelease ⬇️
www.aging-us.com/news-room/dn...

#aging #epigeneticclocks #dnamethylation #oa #publishing #press
DNA Methylation Clocks May Require Tissue-Specific Adjustments for Accurate Aging Estimates | Aging
Our results suggest that forensic applications of DNAm clocks using non-blood tissue types will provide age estimates that are not as accurate as predictions based on blood, especially if using clock....
www.aging-us.com
February 12, 2025 at 8:03 PM
jsantoyo.bsky.social
Snappy: fast identification of DNA methylation motifs based on Oxford Nanopore reads. #DNAmethylation #BacterialDNA @nanoporetech.com #Sequencing #Bioinformatics #Genomics @bioinfoadv.bsky.social
academic.oup.com/bioinformati...
November 28, 2025 at 4:00 PM
antibodies-dot-com.bsky.social

This year also brought impressive progress in the use of ChIP-based technologies in #LiquidBiopsies. Several notable papers described changes in #DNAmethylation as #BioMarkers for #cancer.
ChIP Antibodies | Antibodies.com
Choose the best ChIP antibodies for your research, including those against histones, histone modifications, transcription factors and mo re.
www.antibodies.com
December 5, 2025 at 7:43 AM
cvia-journal.org
This research letter integrates #MultiOmics & #MendelianRandomization analyses to identify #PANoptosis genes #BCL2L1 and UBC as key regulators of #MyocardialInfarction (MI) via #DNAMethylation, revealing BCL2L1 as a promising therapeutic target for MI intervention.

#OpenAccess: tinyurl.com/2yxas89v
Potential Therapeutic Targets of PANoptosis for Myocardial Infarction: A Summary-Data-Based Mendelian Randomization Study Integrating eQTL, mQTL, and Multi-GWAS Data
This study explores PANoptosis as a therapeutic target for myocardial infarction using Mendelian randomization and multi-omics data analysis.
tinyurl.com
November 6, 2025 at 12:32 PM
biorxivpreprint.bsky.social
Islands of Signal and Transcriptomic Sequencing: A Foundation Model for Mutation and Lineage Prediction based on DNAMethylation and RNA-seq https://www.biorxiv.org/content/10.64898/2025.12.01.691534v1
December 2, 2025 at 10:46 PM
aging-us.bsky.social
📈 #Trending:
A new #research paper was recently #published in Volume 17 Issue 3, entitled "DNA methylation entropy is a biomarker for aging."

#PressRelease ⬇️
www.aging-us.com/news-room/dn...

#aging #epigenetics #dna #dnamethylation #epigeneticclocks #openaccess #press #publishing
DNA Methylation Entropy: A New Way to Track and Predict Aging | Aging
"We find that epigenetic clocks based on the entropy of methylation states predict chronological age with similar accuracy as common approaches that are based on methylation levels of individual ...
www.aging-us.com
April 16, 2025 at 10:34 AM