#DSBS
DSBs udgave af spor 9 3/4
September 21, 2026 at 7:58 AM
København Hovedbanegården bygges for tiden om til noe som kanskje blir bra en gang. I mellomtiden har jeg søkt tilflukt i DSBs 1st Class Lounge.

Jeg er ikke den eneste.

DSB slipper inn reisende med første klasse interrail pass i sine såkalte lounger, noe Deutche Bahn ikke gjør.
September 22, 2026 at 7:40 AM
Site-specific, multi-kilobase insertions and over-writes in mammalian cells, without DSBs, HDR, recombinases, integrases, transposases, or active cell cycling? Using fully or predominantly single-stranded DNA donors?

1/15
April 29, 2026 at 3:46 PM
Kan se at DSBs store forårskampagne er godt i gang.. 🙈🚉
April 15, 2026 at 6:38 AM
Power is out, so I guess we are making @pinnyarcade.bsky.social DSBs for the rest of the night. #pinnyarcade #pin
November 20, 2024 at 3:52 AM
DSBs kommunikationschef har endelig fundet den orange arbejdsjakke frem🥰
December 23, 2025 at 6:18 AM
DSBs højtalerudkald sagde fejlagtigt at toget ikke kørte videre end Kbh H; men blev øjeblikkeligt korrekset af en medarbejder:
"I skal ikke lytte til computeren", og hvis det ikke er dagens bedste råd, ved jeg ikke hvad er.
July 30, 2025 at 6:15 AM
Jeg har en times overgang på Køben H, og har for første gang oppdaget og nyttiggjort meg DSBs lounge for første klasse togpassasjerer.

Interrail pass første klasse billett er tilstrekkelig.

I sydenden av stasjonsområdet. Tilgang med heis for eldre damer (og andre).

Kaffeautomat og frukt, gratis.
November 11, 2025 at 12:01 PM
Effektivt inntak av currywurst i dag, hos Schweinske.

Toppetasje på Hamburg Hbf

Det blir LITE mat resten av dagen, DSBs tog til Køben er en kulinariak ørken.

Så jeg gikk for König-varianten.

Fortsatt gamle & utrangerte DB-vogner på denne strekningen, for øvrig.

DSBs nyinnkjøp lar vente på seg.
November 22, 2024 at 2:06 PM
København Hovedbanegården, sett fra DSBs 1. class lounge.

Hovedbanegården er klassisk interiørdesign, nå i stor grad ødelagt av containere plassert for salg av junk food.

Fint å være gjest hos DSB, her er fri tilgang til mye, ikke minst toalett med stoffhåndklær til håndvask.

Og brukbar kaffe.
March 31, 2026 at 10:48 AM
New preprint from the lab @kaelamakins.bsky.social Genetic interactions between 53BP1-RIF1 and DNA-PKcs for DSB repair outcomes. www.biorxiv.org/content/10.1...
53BP1/RIF1 and DNA-PKcs show distinct genetic interactions with diverse chromosomal break repair outcomes.
DNA double strand breaks (DSBs) are the effective lesion of cancer radiotherapy and induce gene editing. 53BP1 accumulates at DSBs and is implicated in end joining (EJ) repair, but its influence on DS...
www.biorxiv.org
May 12, 2025 at 6:53 PM
出演情報は更新されます

今日はDSBSカメラ更新中にカメラ本体死んで整備ミス報告書
September 24, 2026 at 1:35 PM
Introducing Dexter Davis, a deep-sea biologist interested in communicating his science through art. His work is inspired by traditional taxonomic plates - such as this beautiful illustration of characteristic hydrothermal vent fauna of the East Pacific Rise. #dsbsoc #sciart #dsbs #dsbsart
March 15, 2025 at 1:18 PM
Here is the paper by the Keeney lab:
www.biorxiv.org/content/10.1...
November 23, 2024 at 9:27 AM
Min arbejdscomputer og mit dia-udstyr. Og dsbs kundeservice har åbent fra 8 til 16
Min kuffert er på vej til Ålborg. Desværre skiftede jeg tog i Vejle. Skyd mig.
August 24, 2026 at 4:40 PM
Jeg noterer lige at man stadig ikke kan købe billetter til Malmø på DSBs app.
Altså nu, i dag, i 2026.
March 11, 2026 at 9:32 PM
tomodachi life accurately recreating the events of dsbs???
April 27, 2026 at 2:38 AM
Morgenstemning, Hamburg Hbf.

En noe kaotisk morgen. Det kom motstridende informasjon om DSBs TALGO-tog til Hamburg 10:52. Så jeg ringte DSB udland, de sa toget gikk.

Og jeg dro til Hamburg Hbf, der det viste seg at det IKKE gikk. I stedet: evfemismen Togbus.

Det viser seg også at DSBs øvrige

1/
January 3, 2026 at 11:23 AM
DSBs disrupt genomes, triggering a mechanism that halts replication initiation at damage sites. Insights into cancer's replication resilience! PMID:39972127, Nature 2025, @Nature https://doi.org/10.1038/s41586-024-08557-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Mechanism for local attenuation of DNA replication at double-strand breaks | Nature
DNA double-strand breaks (DSBs) disrupt the continuity of the genome, with consequences for malignant transformation. Massive DNA damage can elicit a cellular checkpoint response that prevents cell proliferation1,2. However, how highly aggressive cancer cells, which can tolerate widespread DNA damage, respond to DSBs alongside continuous chromosome duplication is unknown. Here we show that DSBs induce a local genome maintenance mechanism that inhibits replication initiation in DSB-containing topologically associating domains (TADs) without affecting DNA synthesis at other genomic locations. This process is facilitated by mediators of replication and DSBs (MRDs). In normal and cancer cells, MRDs include the TIMELESS–TIPIN complex and the WEE1 kinase, which actively dislodges the TIMELESS–TIPIN complex from replication origins adjacent to DSBs and prevents initiation of DNA synthesis at DSB-containing TADs. Dysregulation of MRDs, or disruption of 3D chromatin architecture by dissolving T
doi.org
April 2, 2025 at 1:10 PM
Om jag numera är ägare till fyra kuvert av DSBs avlagda förstaklasservis i benporslin från Royal Doulton? Eventuellt.
August 5, 2026 at 8:03 PM
Dette er hvorfor jeg synes DSBs beredskapsråde burde inkludere et punkt om minimum 5 terabyte med piratkopiert film og musikk.
November 15, 2024 at 8:45 PM
Skal lige huske at rose DSBs app. Den er sgu blevet god og brugervenlig. Rejsekortet er endeligt overflødigt!
November 25, 2024 at 7:52 AM
Thrilled to share that my postdoc research is published today in @science.org! We found that DNA repair uses cohesin complexes to build new chromatin loops that guide the homology search and boost accurate repair! 1/n
www.science.org/doi/10.1126/...
Cohesin drives chromatin scanning during the RAD51-mediated homology search
Cohesin folds genomes into chromatin loops, the roles of which are under debate. We found that double-strand breaks (DSBs) induce de novo formation of chromatin loops in human cells, with the loop bas...
www.science.org
December 4, 2025 at 9:50 PM
DSBs are now live! Also be sure to check out our mystery collections, available through May 14th at store.penny-arcade.com/collections/...
April 18, 2025 at 11:11 PM
I am happy to share that my postdoctoral work in the @gerlichlab.bsky.social at @imbavienna.bsky.social is finally out 🎉!
Our study reveals how cohesin guides focused and accurate homology search.
Read more 👉 www.science.org/doi/10.1126/...
Follow along for key insights and updates! 🧵
Cohesin guides homology search during DNA repair using loops and sister chromatid linkages
Accurate repair of DNA double-strand breaks (DSBs) is essential for genome stability, and defective repair underlies diseases such as cancer. Homologous recombination uses an intact homologous sequenc...
www.science.org
December 4, 2025 at 8:18 PM