#EBV
I’d put it differently. EBV is almost certainly necessary (but not sufficient) for MS. So prevent EBV and you prevent MS. But most people who get EBV (and most people do) never get MS. EBV puts the bullet in the chamber but things unknown pull the trigger.
February 13, 2026 at 6:07 AM
Continuing after lunch, we're on the #MECFS panel, along with #Lyme and #EBV. Alt text in reply. 🧪
September 23, 2026 at 6:06 PM
99.99% of people who get EBV don’t get HL, but most people who get HL wouldn’t have gotten it without first getting EBV.
September 8, 2025 at 1:16 AM
guess what reactivates EBV
NEW: The Epstein-Barr virus lies dormant in the bodies of billions of people - but for some it is linked to serious chronic and even deadly conditions, including cancers. Now scientists have identified 22 genes that could help identify those most at risk.

www.ft.com/content/815d...
Scientists link 22 genes to deadly risks from common virus
Research probes persistence of Epstein-Barr virus that can cause serious illnesses, including cancers
www.ft.com
January 29, 2026 at 8:48 AM
More smoking gun evidence for the role of Epstein-Barr virus (EBV) in multiple sclerosis. Elevated EBV-specific lymphocytes in cerebrospinal fluid
www.pnas.org/doi/abs/10.1...
January 8, 2024 at 11:20 PM
Immunsystem dauerhaft „verwirren“.

Platz 3) Epstein-Barr-Virus (EBV) (häufigster mononucleosis-assoziierter Trigger):
Sehr häufig. Viele Patienten berichten von einer Mononukleose („Drüsenfieber“) oder einem EBV-Reaktivationsschub als Beginn.
September 20, 2026 at 1:03 PM
EBV-Seq enables identification of EBV-infected cells. Therefore patients with lupus were shown to have been infected with very specific memory B cells, reprogrammed, and act as drivers for autoimmunity overall.
September 23, 2026 at 6:40 PM
(I've been thinking about the potential for tx of #MECFS by EBV vaccination for some time. Talked to a pharma rep about it at one of these conferences...)

She is doing a trial soon for lupus using the same EBV vaccine as that used for MS.
September 23, 2026 at 6:42 PM
EBV also precursor to Burkitt's Lymphoma. 🙋‍♂️ for some.
February 13, 2026 at 6:51 AM
In 2022, the necessary but not sufficient cause of MS was proven to my satisfaction: Epstein-Barr Virus (EBV). In contrast to what RFK Jr. would have you believe, an EBV vaccine could possibly eliminate MS from the face of the earth. Vaccines don’t cause it.

www.science.org/content/arti...
Two decades of soldiers’ medical records implicate common virus in multiple sclerosis
Vaccines under development against Epstein-Barr virus might prevent rare, devastating disease
www.science.org
July 8, 2025 at 10:07 PM
Whoah

EBV not only causes multiple sclerosis, it also might be the root of SLE

www.science.org/doi/10.1126/...

An EBV vaccine to rid ourselves of these horrible autoimmune conditions (and many cancers)?

#lupus #medsky #RheumSky

@christosargyrop.bsky.social
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
www.science.org
November 13, 2025 at 11:05 PM
And beyond that if anyone has questions we should ask a virologist, I’m just a neuroscientist from a small town whose mind has been blown by the MS/EBV studies
February 13, 2026 at 5:57 AM
Today in @nature.com, we describe how discarded reads in biobank-scale WGS can help resolve the genetic predictors and consequences of Epstein-Barr Virus (EBV) infection.

Wonderful working with @ryandhindsa.bsky.social @sherrynyeo.bsky.social @erinmayc.bsky.social

www.nature.com/articles/s41...
Population-scale sequencing resolves determinants of persistent EBV DNA - Nature
Population-scale WGS reveals genetic determinants of persistent EBV DNA, linking immune regulation—especially antigen processing and MHC class II variation—to EBV persistence and heterogeneous di...
www.nature.com
January 28, 2026 at 5:07 PM
Images are very slow to load on the NIH wireless, so let me just narrate.

While everyone is exposed to EBV, people with lupus respond immunologically differently to EBV than people without lupus do.
September 23, 2026 at 6:33 PM
A new study provides evidence of a biological mechanism for how Epstein-Barr Virus (EBV) may trigger lupus.

EBV seems to reprogram B-cells at the beginning of a cascade that ultimately results in autoimmunity.

The authors mention that EBV is a cause of MS, and may be related to LongCOVID.
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
www.science.org
November 13, 2025 at 1:45 AM
I got mono (EBV) in 1982, was diagnosed with chronically active EBV in 1985, and was diagnosed with lupus (after years of positive ANA & anti-DNA tests) in 2012. Suffice it to say that EBV has had a profound affect on my life. Oh, and EBV gave my late husband type 1 diabetes at age 20.
Researchers also believe EBV plays a role in a wide range of serious conditions — from lupus and certain cancers to rheumatoid arthritis — and may trigger some cases of chronic fatigue syndrome. Some suspect it could be a hidden driver of long Covid.
www.bloomberg.com/news/article...
The Silent Virus Behind Mono Is Now a Prime Suspect in Major Diseases
Epstein-Barr virus, which causes glandular fever, was once dismissed as a rite of passage. Scientists now link it to cancer and multiple sclerosis.
www.bloomberg.com
June 8, 2025 at 8:23 AM
„EBV wurde jahrelang als milde Übergangserkrankung abgetan. Diese Sichtweise ändert sich jedoch rapide, seit eine Studie aus dem Jahr 2022 eindeutige Belege dafür lieferte, dass EBV ein Auslöser von Multipler Sklerose ist.“
Wie persistierende Viruserkrankungen die menschliche Gesundheit unbemerkt schädigen können

EBV, das stille Virus hinter Mononukleose, ist jetzt ein Hauptverdächtiger bei schweren Krankheiten: Wissenschaftler bringen es heute mit Krebs, MS, Lupus, Long COVID und ME/CFS in …
December 26, 2025 at 10:39 PM
November 14, 2025 at 11:09 AM
12/1 Entwicklung von Präventionsstrategien, wie z. B. Impfstoffen gegen EBV, und zielgerichteten Therapien zur Behandlung EBV-assoziierter Erkrankungen.
May 28, 2025 at 11:26 AM
schulpflichtigen Kinder, die in Klassen ohne Schutzmaßnahmen sitzen (lernen und arbeiten)

#Stopspreadingdisability #maskup #covid19 #cleanair #Enteroviren #EpsteinBarrVirus #EBV
September 21, 2026 at 7:41 PM
Epstein-Barr Virus #EBV was linked to #MultipleSclerosis - now a plausible cause has been found, misidentification by longterm memory T-cells that pick on the wrong protein, ANO2, instead of the EBV-antigen. Massive inflection towards the elimination of MS!!!
🧪🧠Cell www.cell.com/cell/fulltex...
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
Researchers identified anoctamin-2 (ANO2) as a frequent autoimmune target in multiple sclerosis, with T cell responses against ANO2 occurring in over half of patients. These ANO2-specific T cells shar...
www.cell.com
January 15, 2026 at 1:41 AM
And covid may trigger EBV reactivation causing long covid
February 13, 2026 at 7:21 AM
So the next question they asked was whether EBV reactivation was associated with the transition to lupus

They found that VCA IgG and EA IgG were associated with transitioning to SLE

They also wondered if EBV reactivation was associated with lupus than HCs, and this appeared to be the case, too.
September 23, 2026 at 6:35 PM
God the more you read about EBV the more it’s like “why is this a thing that exists”
October 1, 2025 at 11:40 AM
This paper is part of a huge surge forward in scientific understanding of disease. We have gone from not knowing EBV causes MS to unlocking **how** EBV causes MS, *like that*. 1/2
January 15, 2026 at 5:57 AM