#EpigeneticEditing
LightNews LightNews
scribetx.bsky.social
Join us at today's @keystonesymposia.bsky.social Precision Genome Engineering conference, where we're presenting our latest #EpigeneticEditing advances at 7:30pm.

📣 ADDing a Lock to Epigenome Editing: DNMT3A Allostery Enhances Specificity and Potency of #CRISPR-CasX-based Epigenetic Repressors
March 10, 2026 at 6:34 PM
scribetx.bsky.social
Happening TODAY at #JPM2026!

Don’t miss our CEO @benjaminloakes.bsky.social’s presentation at the J.P. Morgan Healthcare Conference (8:30 am PT) and panel on #biotech innovation at Fierce JPM Week (3:00 pm PT).

#JPM26 #CRISPR #GeneEditing #EpigeneticEditing #CVD
January 14, 2026 at 3:03 PM
epigenometech.bsky.social
Epigenetics Update - A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels go.nature.com/4hvfHef

Research by Frederic Tremblay (Chroma Medicine) in Nat Med

#Epigenetics #EpigeneticEditing
---

Empower your research with epigenome.us
February 11, 2025 at 8:52 AM
scribetx.bsky.social
Read the full report in our press release: www.businesswire.com/news/home/20...

@eassociety.bsky.social #CRISPR #EpigeneticEditing #CVD
www.businesswire.com
May 28, 2026 at 12:02 PM
scribetx.bsky.social
Read the BiopharmaTrend article: www.biopharmatrend.com/news/scribe-...

Dive deeper into the science with our preprint: www.biorxiv.org/content/10.6...

@biorxivpreprint.bsky.social #CRISPR #Epigenetics #EpigeneticEditing
www.biorxiv.org
February 13, 2026 at 6:16 PM
scribetx.bsky.social
NEW PREPRINT: Introducing an additional regulatory layer for enhanced precision and potency in #CRISPR-CasX-based epigenetic medicine.

Press release and preprint links below 🧵

#EpigeneticEditing #Epigenetics
January 20, 2026 at 1:13 PM
epigenometech.bsky.social
Epigenetics Update - Cell-type- and locus-specific epigenetic editing of memory expression go.nature.com/4oCNoxu

Johannes Gräff (EPFL, Lausanne) reporting in Nat Genet

#Epigenetics #EpigeneticEditing #Memory
---

Discover the breakthrough at epigenometech.com
October 30, 2025 at 1:56 PM
epigenometech.bsky.social
Epigenetics Update - Fertile androgenetic mice generated by targeted epigenetic editing of imprinting control regions bit.ly/4niGVIi

Yanchang Wei (Shanghai Jiao Tong University) in PNAS

#Epigenetics #EpigeneticEditing #Imprinting #DNAme

---
Gain deeper insights with epigenometech.com
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
bit.ly
June 25, 2025 at 1:25 PM
scribetx.bsky.social
More details on our clinical trial and commentary from Scribe CEO @benjaminloakes.bsky.social and Principal Investigator Stephen Nicholls (Monash Health’s Victorian Heart Hospital, Victorian Heart Hospital):

www.businesswire.com/news/home/20...

#CVD #HeartHealth #CRISPR #EpigeneticEditing
www.businesswire.com
May 21, 2026 at 12:03 PM
medchemexpress.bsky.social
📚#EpigeneticEditing
Rewires gene expression without altering #DNA—via reversible DNA & histone modifications. Promising for #GeneRegulation in genetic disorders & cancer Challenges: delivery, epigenetic memory, biomarkers. A shift from gene repair → reprogramming beyond #CRISPR
🔗 ow.ly/9JcL50Yw9AT
March 25, 2026 at 1:01 AM
scribetx.bsky.social
Our co-founder & CEO @benjaminloakes.bsky.social will present at the 44th Annual J.P. Morgan Healthcare Conference.

Join us on Wednesday, January 14 at 8:30 a.m. PT to hear what we have in store for 2026.

#JPM2026 #CRISPR #GeneEditing #EpigeneticEditing #CVD
December 15, 2025 at 2:07 PM
scribetx.bsky.social
Coming up next week at #JPM2026:

Our CEO @benjaminloakes.bsky.social will speak at the J.P. Morgan Healthcare Conference and Fierce JPM Week. Don’t miss them on Wednesday, January 14 at 8:30 a.m. and 3:00 p.m. PT!

Links in 🧵 #CRISPR #GeneEditing #EpigeneticEditing #CVD
January 7, 2026 at 7:34 PM
epigenometech.bsky.social
Epigenetics Review - Epigenetic editing: from concept to clinic go.nature.com/3LZJjpi

Marianne G. Rots (University of Groningen) reporting in Nat Rev Drug Disc

#Epigenetics #Review #EpigeneticEditing
---

Gain deeper insights into gene regulation; epigenometech.com
Epigenetic editing: from concept to clinic - Nature Reviews Drug Discovery
Epigenetic editing has emerged as a powerful hit-and-run approach to precise modification of gene expression without altering the underlying DNA sequence. This Review explores the therapeutic potentia...
go.nature.com
November 27, 2025 at 12:11 PM
jaffeab.bsky.social
Like drug discovery, a company's journey is rarely, if ever, a straight line. Best of luck to former @chromamedicine
colleagues in this next phase of the journey to bring #epigeneticediting medicines to patients as
@nchromabio

www.statnews.com/2024/12/11/c...
Gene-editing field sees another merger, this time between Chroma Medicine and Nvelop Therapeutics
In industry parlance, the deal joins a “delivery” company with a “cargo” company — fusing the two key pieces needed to build a genetic medicine.
www.statnews.com
December 11, 2024 at 1:29 PM
scribetx.bsky.social
🧬 @economist.com breaks down epigenetic medicine, the next frontier for CRISPR-based therapies:

→ How #EpigeneticEditing works
→ Potential safety advantages
→ How genes like PCSK9 that Scribe is focused on could be targeted to reduce LDL cholesterol and cardiovascular risk
June 23, 2026 at 7:21 PM
scribetx.bsky.social
♥️ How our CRISPR by Design engineering approach integrates engineering of both the XE foundation to ELXR silencing machinery to enable Scribe’s lead cardiometabolic asset for LDL-C lowering

@asgct.bsky.social #CRISPR #EpigeneticEditing #GeneEditing
May 18, 2026 at 12:06 PM
scribetx.bsky.social
ICYMI learn more in @endpts.com about our plans to enter the clinic in mid-2026 with STX-1150, and our broader work to deliver on the potential of #CRISPR and nature’s blueprint for better cardiovascular health.

endpoints.news/scribe-thera...

#EpigeneticEditing #Epigenetics #HeartHealth #OurHearts
Scribe Therapeutics plans to test cholesterol-lowering epigenetic editing therapy
The company’s lead program is an epigenetic silencing therapy designed to turn off genes without altering the underlying genetic code.
endpoints.news
January 27, 2026 at 6:03 PM
scribetx.bsky.social
We’re headed to #ESGCT2025 to share our latest #CRISPR #EpigeneticEditing data. Check out our presentation on Thursday, Oct. 9!

🧬 Engineering enhanced epigenetic editors: novel repressor domains drive potent and durable therapeutic gene silencing in non-human primates
October 6, 2025 at 5:01 PM
scribetx.bsky.social
With #CRISPR, we have the opportunity to move beyond treating symptoms to tackling the root causes of disease.

🎥 Watch the TEDx talk to see what the future of genetic medicine looks like: www.youtube.com/watch?v=RVde...

#GeneEditing #EpigeneticEditing
The Age of CRISPR: Engineering the Future of Genetic Medicine | Benjamin Oakes | TEDxBerkeley
YouTube video by TEDx Talks
www.youtube.com
July 28, 2025 at 5:32 PM
scribetx.bsky.social
💡 Read The Scientist's latest Innovation Spotlight interviewing our CEO @benjaminloakes.bsky.social about how next-generation #CRISPR #GeneEditing and #EpigeneticEditing tools are reshaping treatment for highly prevalent conditions like cardiometabolic disease.

www.the-scientist.com/getting-to-t...
Getting to the Heart of CRISPR-Based Therapies
Benjamin Oakes from Scribe Therapeutics shares how exciting advancements in CRISPR-based gene and epigenetic editing therapies impact the future of cardiovascular and cardiometabolic disease managemen...
www.the-scientist.com
July 25, 2025 at 4:00 PM
scribetx.bsky.social
📊 #EpigeneticEditing: At EAS, our late-breaker spotlighted that Scribe’s novel epigenetic silencer, ELXR, achieves 9+ months of >50% LDL-C reduction in non-human primates ➡️ surpassing the current standard of care therapies for LDL-C lowering.
May 22, 2025 at 1:05 PM
epigenometech.bsky.social
Epigenetics Update – Design of optimized epigenetic regulators for durable gene silencing with application to PCSK9 in nonhuman primates go.nature.com/4mPi3X7

#Epigenetics #GeneSilencing #EpigeneticEditing

---
Discover the breakthrough at epigenometech.com
October 6, 2025 at 10:53 AM