📅 Save the date! The Molecular Biosystems Conference turns 10 🎉
Join us in Puerto Varas, Chile, Sept 27 to Oct 1, 2027, for the premier event on gene regulation & functional genomics in Latin America.
Keynote Speakers: Geneviève Almouzni (FR) and Joanna Wysocka (US).
#MBioSys27 #GeneRegulation
Join us in Puerto Varas, Chile, Sept 27 to Oct 1, 2027, for the premier event on gene regulation & functional genomics in Latin America.
Keynote Speakers: Geneviève Almouzni (FR) and Joanna Wysocka (US).
#MBioSys27 #GeneRegulation
October 29, 2026 at 12:55 PM
📅 Save the date! The Molecular Biosystems Conference turns 10 🎉
Join us in Puerto Varas, Chile, Sept 27 to Oct 1, 2027, for the premier event on gene regulation & functional genomics in Latin America.
Keynote Speakers: Geneviève Almouzni (FR) and Joanna Wysocka (US).
#MBioSys27 #GeneRegulation
Join us in Puerto Varas, Chile, Sept 27 to Oct 1, 2027, for the premier event on gene regulation & functional genomics in Latin America.
Keynote Speakers: Geneviève Almouzni (FR) and Joanna Wysocka (US).
#MBioSys27 #GeneRegulation
🧬 Time and space in #GeneRegulation
This research in #Arabidopsis thaliana reveals how key regulators vary across cells and throughout the day, highlighting the importance of time and cellular resolution in plant research. doi.org/10.1111/plb....
#PlantScience
@plantsciencedbg.bsky.social
This research in #Arabidopsis thaliana reveals how key regulators vary across cells and throughout the day, highlighting the importance of time and cellular resolution in plant research. doi.org/10.1111/plb....
#PlantScience
@plantsciencedbg.bsky.social
Time‐ and space‐resolved transcriptional regulation in <fi>Arabidopsis thaliana</fi>
Transcript abundance patterns in time and space of kinases, E3 ligases and transcription factors in Arabidopsis thaliana demonstrate ample room for dynamic and specific regulation of metabolism and s....
onlinelibrary.wiley.com
November 3, 2026 at 4:34 PM
🧬 Time and space in #GeneRegulation
This research in #Arabidopsis thaliana reveals how key regulators vary across cells and throughout the day, highlighting the importance of time and cellular resolution in plant research. doi.org/10.1111/plb....
#PlantScience
@plantsciencedbg.bsky.social
This research in #Arabidopsis thaliana reveals how key regulators vary across cells and throughout the day, highlighting the importance of time and cellular resolution in plant research. doi.org/10.1111/plb....
#PlantScience
@plantsciencedbg.bsky.social
𝗙𝗿𝗼𝗺 𝗳𝗹𝗼𝘄𝗲𝗿 𝗰𝗶𝗿𝗰𝘂𝗶𝘁 𝘁𝗼 𝘁𝗲𝘀𝘁𝗮𝗯𝗹𝗲 𝗗𝗡𝗔.
Darwin connects petal identity, MBW regulation, anthocyanin production, transport and pH. CloneLab builds four AN2 construct states and finds a PstI digest resolving all four.
Predictions require plant validation.
#GeneRegulation #PlantScience #Bioinformatics
Darwin connects petal identity, MBW regulation, anthocyanin production, transport and pH. CloneLab builds four AN2 construct states and finds a PstI digest resolving all four.
Predictions require plant validation.
#GeneRegulation #PlantScience #Bioinformatics
October 26, 2026 at 12:47 PM
𝗙𝗿𝗼𝗺 𝗳𝗹𝗼𝘄𝗲𝗿 𝗰𝗶𝗿𝗰𝘂𝗶𝘁 𝘁𝗼 𝘁𝗲𝘀𝘁𝗮𝗯𝗹𝗲 𝗗𝗡𝗔.
Darwin connects petal identity, MBW regulation, anthocyanin production, transport and pH. CloneLab builds four AN2 construct states and finds a PstI digest resolving all four.
Predictions require plant validation.
#GeneRegulation #PlantScience #Bioinformatics
Darwin connects petal identity, MBW regulation, anthocyanin production, transport and pH. CloneLab builds four AN2 construct states and finds a PstI digest resolving all four.
Predictions require plant validation.
#GeneRegulation #PlantScience #Bioinformatics
Aarhus University (@au.dk) is hiring:
Assistant Professor in Drosophila Transposon Regulation
#assistantprofessor #biology #generegulation
Assistant Professor in Drosophila Transposon Regulation
#assistantprofessor #biology #generegulation
October 24, 2026 at 8:17 AM
Aarhus University (@au.dk) is hiring:
Assistant Professor in Drosophila Transposon Regulation
#assistantprofessor #biology #generegulation
Assistant Professor in Drosophila Transposon Regulation
#assistantprofessor #biology #generegulation
2/5:
scReGAT builds a knowledge-guided regulatory graph using validated cRE-gene and TF-gene interactions. A Graph Attention Network (GAT) then predicts gene expression and assigns interpretable regulatory scores to each edge.
#GeneRegulation
scReGAT builds a knowledge-guided regulatory graph using validated cRE-gene and TF-gene interactions. A Graph Attention Network (GAT) then predicts gene expression and assigns interpretable regulatory scores to each edge.
#GeneRegulation
October 23, 2026 at 9:20 AM
2/5:
scReGAT builds a knowledge-guided regulatory graph using validated cRE-gene and TF-gene interactions. A Graph Attention Network (GAT) then predicts gene expression and assigns interpretable regulatory scores to each edge.
#GeneRegulation
scReGAT builds a knowledge-guided regulatory graph using validated cRE-gene and TF-gene interactions. A Graph Attention Network (GAT) then predicts gene expression and assigns interpretable regulatory scores to each edge.
#GeneRegulation
Vitamin D isn't "just a vitamin"—it's a steroid hormone controlling 200+ genes across immunity, bone, and endocrine systems. New understanding: …
#Bonehealth #Clinicalbiochemistry #Endocrinesystem #Generegulation #Hormonesignaling
#Bonehealth #Clinicalbiochemistry #Endocrinesystem #Generegulati…
#Bonehealth #Clinicalbiochemistry #Endocrinesystem #Generegulation #Hormonesignaling
#Bonehealth #Clinicalbiochemistry #Endocrinesystem #Generegulati…
Vitamin D: The Hormone Your Cells Are Listening To
Vitamin D isn't "just a vitamin"—it's a steroid hormone controlling 200+ genes across immunity, bone, and endocrine systems. New understanding: …
#Bonehealth #Clinicalbiochemistry #Endocrinesystem #Generegulation #Hormonesignaling
news.gmj.ge
October 22, 2026 at 11:26 AM
Vitamin D isn't "just a vitamin"—it's a steroid hormone controlling 200+ genes across immunity, bone, and endocrine systems. New understanding: …
#Bonehealth #Clinicalbiochemistry #Endocrinesystem #Generegulation #Hormonesignaling
#Bonehealth #Clinicalbiochemistry #Endocrinesystem #Generegulati…
#Bonehealth #Clinicalbiochemistry #Endocrinesystem #Generegulation #Hormonesignaling
#Bonehealth #Clinicalbiochemistry #Endocrinesystem #Generegulati…
🧬 Having a gene does not mean the cell is actually using it.
Cells regulate which genes are active, when, where, and how strongly.
Apparently DNA has bureaucracy. 😂
sciencescandal.com/scandals/you...
#StayCurious #Genetics #GeneRegulation #DNA #GeneExpression
Cells regulate which genes are active, when, where, and how strongly.
Apparently DNA has bureaucracy. 😂
sciencescandal.com/scandals/you...
#StayCurious #Genetics #GeneRegulation #DNA #GeneExpression
Your DNA Has Its Own Bureaucracy!
Having the DNA is only the beginning. Cells decide when, where, and how much gets used. Transcription factors, enhancers, and chromatin have all been implicated in management.
sciencescandal.com
October 21, 2026 at 1:06 PM
🧬 Having a gene does not mean the cell is actually using it.
Cells regulate which genes are active, when, where, and how strongly.
Apparently DNA has bureaucracy. 😂
sciencescandal.com/scandals/you...
#StayCurious #Genetics #GeneRegulation #DNA #GeneExpression
Cells regulate which genes are active, when, where, and how strongly.
Apparently DNA has bureaucracy. 😂
sciencescandal.com/scandals/you...
#StayCurious #Genetics #GeneRegulation #DNA #GeneExpression
Vitamin D is not just a micronutrient—it's an endocrine hormone that controls over 1,200 genes & regulates immunity, bone remodeling, inflamma…
#Bonehealth #Endocrinehormone #Evidencebasedmedicine #Generegulation #Hormonalsignaling
#Bonehealth #Endocrinehormone #Evidencebasedmedicine #Generegul…
#Bonehealth #Endocrinehormone #Evidencebasedmedicine #Generegulation #Hormonalsignaling
#Bonehealth #Endocrinehormone #Evidencebasedmedicine #Generegul…
Vitamin D is an Endocrine Hormone, Not Just a Vitamin
Vitamin D is not just a micronutrient—it's an endocrine hormone that controls over 1,200 genes & regulates immunity, bone remodeling, inflamma…
#Bonehealth #Endocrinehormone #Evidencebasedmedicine #Generegulation #Hormonalsignaling
news.gmj.ge
October 14, 2026 at 9:27 PM
Vitamin D is not just a micronutrient—it's an endocrine hormone that controls over 1,200 genes & regulates immunity, bone remodeling, inflamma…
#Bonehealth #Endocrinehormone #Evidencebasedmedicine #Generegulation #Hormonalsignaling
#Bonehealth #Endocrinehormone #Evidencebasedmedicine #Generegul…
#Bonehealth #Endocrinehormone #Evidencebasedmedicine #Generegulation #Hormonalsignaling
#Bonehealth #Endocrinehormone #Evidencebasedmedicine #Generegul…
The Teves Lab is starting a new chapter! 🧬🔬 We’re delighted to have Divya Pantula join us as a PhD student. We look forward to the new ideas, scientific questions, and discoveries her PhD journey will bring. Here’s to exciting science ahead!
#GeneRegulation #UBC
#GeneRegulation #UBC
October 13, 2026 at 11:53 PM
The Teves Lab is starting a new chapter! 🧬🔬 We’re delighted to have Divya Pantula join us as a PhD student. We look forward to the new ideas, scientific questions, and discoveries her PhD journey will bring. Here’s to exciting science ahead!
#GeneRegulation #UBC
#GeneRegulation #UBC
New from Physiological Genomics: Research Article by J Zhang et al. #Transcriptomic profiling reveals #immunometabolic #generegulation during a 24-h #coldexposure survival simulation in humans 🥶
https://ow.ly/oAyM50ZW406
https://ow.ly/oAyM50ZW406
October 13, 2026 at 2:01 PM
New from Physiological Genomics: Research Article by J Zhang et al. #Transcriptomic profiling reveals #immunometabolic #generegulation during a 24-h #coldexposure survival simulation in humans 🥶
https://ow.ly/oAyM50ZW406
https://ow.ly/oAyM50ZW406
Excited to share a preprint on the structural mechanism of transcriptional activation by human Mediator, studied using integrative structural modeling.
Many thanks to Lacra Bintu for helpful discussions!
www.biorxiv.org/content/10.6...
@generegulation @MED_COMPLEX
Many thanks to Lacra Bintu for helpful discussions!
www.biorxiv.org/content/10.6...
@generegulation @MED_COMPLEX
October 13, 2026 at 5:21 AM
Excited to share a preprint on the structural mechanism of transcriptional activation by human Mediator, studied using integrative structural modeling.
Many thanks to Lacra Bintu for helpful discussions!
www.biorxiv.org/content/10.6...
@generegulation @MED_COMPLEX
Many thanks to Lacra Bintu for helpful discussions!
www.biorxiv.org/content/10.6...
@generegulation @MED_COMPLEX
A layered, orthogonal circuit architecture employs bacterial transcription factors and copper-responsive promoters to achieve precise, tunable #generegulation, enabling dynamic control of multi-gene pathways in #Yarrowia lipolytica with minimized leakage and enhanced performance.
PDF available ⤵️
PDF available ⤵️
ARCANE: ‘A Reprogrammable Circuit Architecture for Non-model Engineering’ enables sophisticated metabolic control in Yarrowia lipolytica - Communications Biology
Communications Biology - ARCANE: ‘A Reprogrammable Circuit Architecture for Non-model Engineering’ enables sophisticated metabolic control in Yarrowia lipolytica
doi.org
October 8, 2026 at 4:00 PM
A layered, orthogonal circuit architecture employs bacterial transcription factors and copper-responsive promoters to achieve precise, tunable #generegulation, enabling dynamic control of multi-gene pathways in #Yarrowia lipolytica with minimized leakage and enhanced performance.
PDF available ⤵️
PDF available ⤵️
The goal is not a fluent black-box answer. It is an inspectable route from a research question to an atlas-grounded hypothesis, evidence boundary, and next experiment.
www.cairninstitute.com/blogs/Darwin...
#Genomics #GeneRegulation #Bioinformatics #AIforScience #PlantScience
www.cairninstitute.com/blogs/Darwin...
#Genomics #GeneRegulation #Bioinformatics #AIforScience #PlantScience
Gene Regulation Skills: Now Supporting Claude, Codex, and Nemotron
www.cairninstitute.com
September 29, 2026 at 10:43 PM
The goal is not a fluent black-box answer. It is an inspectable route from a research question to an atlas-grounded hypothesis, evidence boundary, and next experiment.
www.cairninstitute.com/blogs/Darwin...
#Genomics #GeneRegulation #Bioinformatics #AIforScience #PlantScience
www.cairninstitute.com/blogs/Darwin...
#Genomics #GeneRegulation #Bioinformatics #AIforScience #PlantScience
MRC Laboratory of Medical Sciences is hiring:
Postdoctoral Research Scientist in Gene Regulation and High-Throughput CRISPR Screens
#postdoc #medicine #generegulation
Postdoctoral Research Scientist in Gene Regulation and High-Throughput CRISPR Screens
#postdoc #medicine #generegulation
September 13, 2026 at 8:52 AM
MRC Laboratory of Medical Sciences is hiring:
Postdoctoral Research Scientist in Gene Regulation and High-Throughput CRISPR Screens
#postdoc #medicine #generegulation
Postdoctoral Research Scientist in Gene Regulation and High-Throughput CRISPR Screens
#postdoc #medicine #generegulation
I am rather delighted by this paper. So here’s a thread to tell you why, and why it matters. /1
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Noncoding transcription controls the developmental dynamics of long-range gene regulation
The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely unknown. By using live imaging, we reveal that the ...
www.science.org
September 12, 2026 at 12:13 PM
Single #lncRNA integrates #Inflammatory and #Metabolic signals to regulate #CardiovascularHomeostasis doi.org/10.1016/j.ce... @FitzGerald__Lab #PACERR #GeneRegulation #Cyclooxygenase #TranslationalScience
Redirecting
doi.org
September 8, 2026 at 6:43 PM
Single #lncRNA integrates #Inflammatory and #Metabolic signals to regulate #CardiovascularHomeostasis doi.org/10.1016/j.ce... @FitzGerald__Lab #PACERR #GeneRegulation #Cyclooxygenase #TranslationalScience
RegVelo integrates RNA splicing kinetics and gene regulatory networks to reveal cellular dynamics and fate transitions. This actionable deep learning framework enhances mechanistic insights. #GeneRegulation PMID:42119563, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00457-5
https://www.cell.com/cell/fulltext/S0092-8674(26)00457-5
No description available
www.cell.com
September 3, 2026 at 5:00 PM
RegVelo integrates RNA splicing kinetics and gene regulatory networks to reveal cellular dynamics and fate transitions. This actionable deep learning framework enhances mechanistic insights. #GeneRegulation PMID:42119563, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00457-5
🧬Can a cancer-driving gene protect our genome?
In melanoma, MITF is an oncogene. But a new study shows that in non-melanocytic cancers, its depletion triggers genomic instability & apoptosis.
An amazing case of context-dependent protein duality!
#MolecularBiology #GeneRegulation #GenomeStability
In melanoma, MITF is an oncogene. But a new study shows that in non-melanocytic cancers, its depletion triggers genomic instability & apoptosis.
An amazing case of context-dependent protein duality!
#MolecularBiology #GeneRegulation #GenomeStability
FEBS Press
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2-mediated P53...
doi.org
August 27, 2026 at 10:00 AM
🧬Can a cancer-driving gene protect our genome?
In melanoma, MITF is an oncogene. But a new study shows that in non-melanocytic cancers, its depletion triggers genomic instability & apoptosis.
An amazing case of context-dependent protein duality!
#MolecularBiology #GeneRegulation #GenomeStability
In melanoma, MITF is an oncogene. But a new study shows that in non-melanocytic cancers, its depletion triggers genomic instability & apoptosis.
An amazing case of context-dependent protein duality!
#MolecularBiology #GeneRegulation #GenomeStability
👉 Read the full, detailed analysis on Molecular Integrity: molecularintegrity.substack.com/p/the-calciu...
#MolecularBiology #CancerResearch #GeneRegulation #TranslationalMedicine #MolecularIntegrity
#MolecularBiology #CancerResearch #GeneRegulation #TranslationalMedicine #MolecularIntegrity
How a calcium sensor becomes colorectal cancer's fuel: the role of the HPCAL1-Wnt axis
Exploring the molecular complexes that fuel CRC aggressiveness and the promising role of targeted drug repurposing.
molecularintegrity.substack.com
August 26, 2026 at 6:57 PM
👉 Read the full, detailed analysis on Molecular Integrity: molecularintegrity.substack.com/p/the-calciu...
#MolecularBiology #CancerResearch #GeneRegulation #TranslationalMedicine #MolecularIntegrity
#MolecularBiology #CancerResearch #GeneRegulation #TranslationalMedicine #MolecularIntegrity
Congrats to the Awardees of the 2026 Michael R. Green, MD, PhD, Award in Graduate Research, Andrew Petti (RTI; Wen Xue's Lab) and Brennon Berard (MCCB; Dohoon Kim's Lab). Save the Date for their research presentations: Tuesday Sept 8, 2026 at 11:00am DiMare Center, N1-1500
#generegulation #RNATx
#generegulation #RNATx
August 25, 2026 at 9:47 PM
Congrats to the Awardees of the 2026 Michael R. Green, MD, PhD, Award in Graduate Research, Andrew Petti (RTI; Wen Xue's Lab) and Brennon Berard (MCCB; Dohoon Kim's Lab). Save the Date for their research presentations: Tuesday Sept 8, 2026 at 11:00am DiMare Center, N1-1500
#generegulation #RNATx
#generegulation #RNATx
We are looking for a Bioinformatician (M/F/D) in our Totipotency department, led by Kikuë Tachibana.
❕ Apply until: September 20
❕ lnkd.in/d2SGK4pr
#hiring #jobalert #Bioinformatics #Totipotency #ChromatinReprogramming #GeneRegulation
❕ Apply until: September 20
❕ lnkd.in/d2SGK4pr
#hiring #jobalert #Bioinformatics #Totipotency #ChromatinReprogramming #GeneRegulation
August 13, 2026 at 10:06 AM
We are looking for a Bioinformatician (M/F/D) in our Totipotency department, led by Kikuë Tachibana.
❕ Apply until: September 20
❕ lnkd.in/d2SGK4pr
#hiring #jobalert #Bioinformatics #Totipotency #ChromatinReprogramming #GeneRegulation
❕ Apply until: September 20
❕ lnkd.in/d2SGK4pr
#hiring #jobalert #Bioinformatics #Totipotency #ChromatinReprogramming #GeneRegulation
🚀 study: www.cell.com/cell/fulltex... from @larsplus.bsky.social et al: via enhancer design from scratch, 3 principles emerged: 1) TF binding strength = activation 'or' repression; 2) Same motif ≠ same output in all cell states; 3) 2 activators ≠ activation - combos can repress! #geneRegulation
Design principles of cell-state-specific enhancers in hematopoiesis
Screen of minimalistic enhancers in blood progenitor cells demonstrates widespread
dual activator-repressor function of transcription factors (TFs) and enables the model-guided
design of cell-state-sp...
www.cell.com
May 12, 2025 at 9:37 AM
🚀 study: www.cell.com/cell/fulltex... from @larsplus.bsky.social et al: via enhancer design from scratch, 3 principles emerged: 1) TF binding strength = activation 'or' repression; 2) Same motif ≠ same output in all cell states; 3) 2 activators ≠ activation - combos can repress! #geneRegulation
Fantastic third instalment of the Melbourne Epigenetics Club featuring talks by Lee Wong and Hamish King, and a networking reception
If you’re in Melbourne and interested in #chromatin #epigenetics or #GeneRegulation and interested in attending, visit www.eckmaslab.com/melbourne-ep... 🧪🧬
If you’re in Melbourne and interested in #chromatin #epigenetics or #GeneRegulation and interested in attending, visit www.eckmaslab.com/melbourne-ep... 🧪🧬
November 19, 2024 at 9:04 AM
Fantastic third instalment of the Melbourne Epigenetics Club featuring talks by Lee Wong and Hamish King, and a networking reception
If you’re in Melbourne and interested in #chromatin #epigenetics or #GeneRegulation and interested in attending, visit www.eckmaslab.com/melbourne-ep... 🧪🧬
If you’re in Melbourne and interested in #chromatin #epigenetics or #GeneRegulation and interested in attending, visit www.eckmaslab.com/melbourne-ep... 🧪🧬