#Hexokinase2 does more than fuel cancer metabolism.
This review shows how it regulates #CellDeath, reshapes the #TumorMicroenvironment and promotes immune evasion, highlighting HK2-targeting therapies as promising strategies.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...

#Pericyte #GlucoseMetabolism

Tumor (liver, lung) pericytes
⏫#Hexokinase2
⏬PGAM2
⏫Glycolysis
⏬pro-angiogenic capacity

3-BP, HK2 inhibitor
⏫tumor vesselφ, perfusion, drug delivery
+unaltered vessel/pericyte density

Dr Ping-Pui Wong lab Nat Comms 2021
www.nature.com/articles/s41...