Abstract. As the global population ages, especially in low- and middle-income countries, there is an urgent need to rethink how health in older age is unde

YouTube video by Rogeiro Peraza

Fuentealba and colleagues build and validate a DNA methylation clock of intrinsic capacity (IC) to bridge resource-intensive clinical assessments of IC with molecular readouts of aging, highlighting s...

The Intrinsic Capacity, Frailty and Sarcopenia Research (ICFSR) Task Force convened in March 2025 to discuss geroscience-oriented pre-clinical and cli…

Intrinsic capacity is quickly becoming a preferred way to measure and assess human aging.

The World Health Organization’s intrinsic capacity (IC) framework has shifted focus from functional deficits to preserving abilities in ageing. Howeve…

Abstract. As the global population ages, especially in low- and middle-income countries, there is an urgent need to rethink how health in older age is unde

Abstract. As the global population ages, especially in low- and middle-income countries, there is an urgent need to rethink how health in older age is unde

AbstractBackground. Intrinsic capacity (IC), defined as the composite of physical and mental capacities, is a dynamic indicator of healthy ageing. Understa

Background: Intrinsic capacity (IC) refers to the sum of the physical and mental capacities of an individual. Conventional IC assessment requires substantial temporal and human resources. Digital twin (DT) technology emerges as a promising solution for efficiently mapping ICs. Objective: This study aims to explore older adults’ perspectives on the DT technology and their perceptions of how it could effectively represent their ICs. Methods: A qualitative study was used. Face-to-face semistructured interviews with 23 older adults were conducted. The interviews were transcribed verbatim and analyzed via content analysis approach. Results: The analysis identified five themes and 16 subthemes: (1) “opt for or not my digital twin,” revealing the older adults’ decisions regarding whether to use DT technology for mapping ICs; (2) “my ideal digital avatar,” describing the older adults’ preferences for personalized digital avatar appearances; (3) “my digital twin maps my intrinsic capacity,” highlighting how multimodal reminders and synchronized avatar changes enhanced their comprehension of ICs; (4) “the benefits my digital twin can deliver,” emphasizing the potential of the DT system to provide feedback services to older adults; (5) “some expectations for my digital twin,” outlining their expectations for DT technology. Based on the above insights, a conceptual model, “windmill” model, was further developed to better understand how to build DTs of older adults and map their ICs. Conclusions: DT technology was a promising tool for mapping ICs of older adults. Furthermore, the “windmill” model provided a framework to build tailored DTs. The findings of this study could provide references to develop DT model to support IC management.