#KINNEX
So kinnex.
Was machwa denn heute nich?
June 29, 2025 at 6:50 AM
So kinnex. Würd gern noch quackeln mit euch, aber das bett ruft. N8i
May 5, 2025 at 8:14 PM
Deepest long-read RNA-Seq dataset for one single cell line, multiple time points + replicates using @pacbio.bsky.social Kinnex RNA kit! Wissel et al. show that Kinnex can be used for isoform quantitative analyses: www.biorxiv.org/content/10.1...
www.biorxiv.org
June 12, 2025 at 10:15 PM
The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples
📢 HPRC Release 2 is here!

Now with phased genomes from 200+ individuals, a 5x increase from Release 1.

Explore sequencing data, assemblies, annotations & alignments in our interactive data explorer ⬇️:

humanpangenome.org/hprc-data-re...
May 12, 2025 at 1:52 PM
Look beyond gene-level expression.

New Kinnex prep kits are available now: run full-length RNA on 8-fold for the longest transcripts or 12-fold for throughput. Single-cell moves to 16-fold.

Learn more: https://bit.ly/4APmLfM

#PacBio #Kinnex #RNAseq
October 5, 2026 at 4:23 PM
New Kinnex achievement unlocked! 194Gb with Revio SPRQ! Well deserved @udelaware.bsky.social
Celebrating @udelaware.bsky.social Sequencing Center for their #HiFiSequencing record! 🤯 They generated 194Gb in a single Revio SPRQ run, powering crucial research on biological pest control. #PacBio #Genomics
March 19, 2025 at 8:30 PM
Brooke Peterson-Burch up next at @pacbio.bsky.social Workshop at #PAG33 to talk about gene prediction in crops using Kinnex Iso-Seq.
January 12, 2026 at 10:01 PM
Just released @pacbio.bsky.social Kinnex-10x GEM-X single cell data for both Revio and Vega! Go check out the updated app note and dataset URL!

App note: www.pacb.com/wp-content/u...

Dataset: downloads.pacbcloud.com/public/datas...
www.pacb.com
August 7, 2025 at 4:54 PM
What a huge achievement! 450 human haplotypes. PacBio Kinnex transcriptomic data, Fiber-Seq (nucleosome occupancy), and so much more!
HPRC2: A human pangenome reference with near-complete coverage of common genetic variation https://www.biorxiv.org/content/10.64898/2026.07.21.739710v1
July 23, 2026 at 12:29 AM
Analyzing @pacbio.bsky.social Kinnex full-length (bulk) RNA-Seq data? Here's the troubleshooting guide to help you understand the metrics! Explanation on FLNC reads, SQANTI3/pigeon classification, and artifact filtering. #Bioinformatics 🧬🧪

www.pacb.com/wp-content/u...
www.pacb.com
November 14, 2024 at 12:43 AM
Jeremy Wilkinson (@jewilki.bsky.social) from #PacBio discusses using the Kinnex Kit for high-resolution microbiome species profiling through full-length 16S rRNA sequencing at Poster 315. #PAG32 (3/X)
January 13, 2025 at 11:39 PM
#PacBio is contributing Iso-Seq data to the 1000 Genomes Long Read Sequencing Project using #Kinnex kits and the #Revio system.

This data from 1,000 globally diverse samples will help advance transcript-level insights across populations.

Press release here: bit.ly/4mdzHEe
July 23, 2025 at 3:01 PM
Unlock targeted single-cell sequencing with Twist Exome Enrichment Kits, powered by #PacBio Kinnex. This robust workflow enriches spliced mRNA from single-nuclei libraries for high-res transcript discovery. Check out our tech note & learn more at our #AGBT Lanai Suite 289! bit.ly/3QqD6l5
February 20, 2025 at 8:31 PM
Join #PacBio at #ESHG2025 to explore scalable solutions for human disease research—from PureTarget panels to Kinnex RNA discoveries.

📍 Join us in Milan, 24–27 May.
📄 View the full agenda: bit.ly/3GG9wX7

The future of sequencing starts with HiFi...
May 8, 2025 at 9:29 AM
NEW: Level up your #RNA sequencing with IDT xGen™ Target Capture, powered by #PacBio Kinnex. Check out our tech note on this robust workflow for isoform characterization in targeted genes & connect with us at #AGBT Lanai Suite 289 to learn more! bit.ly/4133tCG 
February 18, 2025 at 9:12 PM
The new Google DeepVariant now works for @pacbio.bsky.social Revio SPRQ chemistry data *and* long-read RNA-Seq (Kinnex / Iso-Seq) data! Go give it a try! 🧬🧪
github.com/google/deepv...
Release DeepVariant 1.8.0 · google/deepvariant
In this release: Small model integration: Speed increased by ~1.7x (40% runtime reduction) for WGS, PacBio, and ONT by introduction of additional small model. The small model identifies easy-to-...
github.com
December 6, 2024 at 8:45 PM
Need long-read sequencing? We just completed the first ever run on @uoregon.bsky.social GC3F core’s new
@pacbio.bsky.social Revio instrument! Perfect for amplicons too long for Illumina, and with Kinnex, you can get >10x more data. Great pricing, no queue, try it: gc3f.uoregon.edu/pacbio-seque...
November 25, 2024 at 2:53 PM
Time is running out! Join us to see how long-read single-cell RNA sequencing uncovers critical mis-splicing patterns in AML, shedding light on disease progression and potential therapeutic targets. Register now: bit.ly/4iiY0z3

#PacBio #Kinnex #RNASeq
March 17, 2025 at 7:07 PM
First, we are looking at FFPE compatibility.

Archival tumor samples are no longer a dead end. PacBio Ampli-Fi protocol and Kinnex concatenation now enable 40X WGS coverage from FFPE tissue, unlocking long read sequencing on one of the most challenging sample types.

#AACR26 #PacBio
April 21, 2026 at 7:40 PM
Use of targeted long-read single cell RNA-Seq w @pacbio.bsky.social Kinnex identified PIK3CA-mutated cells in MCAP-derived sample

www.nature.com/articles/s41...
Defining the transcriptome of PIK3CA-altered cells in a human capillary malformation using single cell long-read sequencing - Scientific Reports
Scientific Reports - Defining the transcriptome of PIK3CA-altered cells in a human capillary malformation using single cell long-read sequencing
www.nature.com
November 13, 2024 at 5:11 PM
Finally, we have the discovery of a resistance mechanism.

Researchers used PacBio Kinnex long read RNA sequencing to detect an EGFR isoform with three kinase domains. This is what seeing cancer completely looks like. 

#AACR26 #PacBio
April 21, 2026 at 8:20 PM
Come see me at my #PAG32 poster on high-resolution #microbiome species profiling at scale with the #Kinnex kit for full-length #16S rRNA sequencing! #PacBio #longreads
January 13, 2025 at 10:50 PM
How does SPRQ transform #Kinnex kits? More reads, flexible pooling, and increased samples per SMRT Cell—all powered by #PacBio innovation. Unlock new possibilities in RNA #sequencing with SPRQ chemistry on #Revio! #PAG32
January 13, 2025 at 9:08 PM
Watch Novogene's free on-demand webinar: Innovations in Genomics: Harnessing HiFi Sequencing & Kinnex Solutions for Comprehensive Insights. Learn how long-read HiFi and Kinnex full-length RNA, single-cell & 16S improve resolution. #Genomics #HiFi #LongRead https://tinyurl.com/4744bmjc
April 17, 2026 at 7:05 AM
Under the agreement, TychoBio plans to use PacBio HiFi and Kinnex sequencing to generate training data for the models.
Pacific Biosciences, TychoBio Partner on AI Models for RNA Therapies
Pacific Biosciences, TychoBio Partner on AI Models for RNA Therapies
ebx.sh
October 6, 2026 at 8:52 PM