A cross-species drug-discovery platform to accelerate the identification of lifespan-extending interventions
A cross-species drug-discovery platform to accelerate the identification of lifespan-extending interventions
Perez, Schoenfeldt et al. present an integrated platform and methodology combining automation and machine learning to evaluate thousands of conditions across >400 compounds in yeasts, nematodes, flies, killifish, and mice, identifying conserved longevity-associated pathways and prioritizing interventions with strong translational potential.
dlvr.it
September 28, 2026 at 7:50 PM
A cross-species drug-discovery platform to accelerate the identification of lifespan-extending interventions
Elephants are increasing their odds of survival by giving up tusks at a genetic level to counter our childish desire for ivory. Flowers in the park are growing shorter so that they're less likely to be spotted and picked by humans. There's the Killifish that thrive in toxic waste
September 28, 2026 at 12:31 PM
Elephants are increasing their odds of survival by giving up tusks at a genetic level to counter our childish desire for ivory. Flowers in the park are growing shorter so that they're less likely to be spotted and picked by humans. There's the Killifish that thrive in toxic waste
Winning and losing experiences differentially alter learning performance and forebrain protein expression in mangrove rivulus killifish, Kryptolebias marmoratus SciReports
Winning and losing experiences differentially alter learning performance and forebrain protein expression in mangrove rivulus killifish, Kryptolebias marmoratus
Scientific Reports, Published online: 28 September 2026; doi:10.1038/s41598-026-72705-6Winning and losing experiences differentially alter learning performance and forebrain protein expression in mangrove rivulus killifish, Kryptolebias marmoratus
dlvr.it
September 28, 2026 at 5:47 AM
Winning and losing experiences differentially alter learning performance and forebrain protein expression in mangrove rivulus killifish, Kryptolebias marmoratus SciReports
Check out this wonderful study of the mosaic organization of the photoreceptor cells in the turquoise killifish by my friend and colleague @nclnoel.bsky.social. The retina is so stunningly beautiful 😍
My work on the turquoise killifish photoreceptor mosaic was published last week - check it out if you’re interested in photoreceptors, cell organization, and pretty pictures!
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Ordered Chaos: Photoreceptor Mosaics in the Larval and Adult Turquoise Killifish (<i>Nothobranchius furzeri</i>)
The annual turquoise killifish (Nothobranchius furzeri) cone photoreceptor mosaic is an ordered lattice but lacks regularity of cone subtypes in adulthood. The cone mosaic differs between life stages...
onlinelibrary.wiley.com
September 28, 2026 at 1:43 AM
Check out this wonderful study of the mosaic organization of the photoreceptor cells in the turquoise killifish by my friend and colleague @nclnoel.bsky.social. The retina is so stunningly beautiful 😍
A Striking New Fish Species Discovered in Amazon
https://www.flakefood.com/918571/a-striking-new-fish-species-discovered-in-amazon/
The good news? The dazzling Laimosemion laranja killifish was just discovered in the Brazilian Amazon. The bad news? The team that discovered it is already …
https://www.flakefood.com/918571/a-striking-new-fish-species-discovered-in-amazon/
The good news? The dazzling Laimosemion laranja killifish was just discovered in the Brazilian Amazon. The bad news? The team that discovered it is already …
A Striking New Fish Species Discovered in Amazon - Fishing & Fishing
The good news? The dazzling Laimosemion laranja killifish was just discovered in the Brazilian Amazon. The bad news? The team that discovered it is already
www.flakefood.com
September 27, 2026 at 4:00 AM
A Striking New Fish Species Discovered in Amazon
https://www.flakefood.com/918571/a-striking-new-fish-species-discovered-in-amazon/
The good news? The dazzling Laimosemion laranja killifish was just discovered in the Brazilian Amazon. The bad news? The team that discovered it is already …
https://www.flakefood.com/918571/a-striking-new-fish-species-discovered-in-amazon/
The good news? The dazzling Laimosemion laranja killifish was just discovered in the Brazilian Amazon. The bad news? The team that discovered it is already …
Why is the turquoise killifish a cool model?
It is a model system for accelerated decrepitude. Their whole lifespan is like, 4-9 months. Soooo, cancer research, neurodegeneration research and more is possible with this model system.
It is a model system for accelerated decrepitude. Their whole lifespan is like, 4-9 months. Soooo, cancer research, neurodegeneration research and more is possible with this model system.
My work on the turquoise killifish photoreceptor mosaic was published last week - check it out if you’re interested in photoreceptors, cell organization, and pretty pictures!
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Ordered Chaos: Photoreceptor Mosaics in the Larval and Adult Turquoise Killifish (<i>Nothobranchius furzeri</i>)
The annual turquoise killifish (Nothobranchius furzeri) cone photoreceptor mosaic is an ordered lattice but lacks regularity of cone subtypes in adulthood. The cone mosaic differs between life stages...
onlinelibrary.wiley.com
September 26, 2026 at 10:34 PM
Why is the turquoise killifish a cool model?
It is a model system for accelerated decrepitude. Their whole lifespan is like, 4-9 months. Soooo, cancer research, neurodegeneration research and more is possible with this model system.
It is a model system for accelerated decrepitude. Their whole lifespan is like, 4-9 months. Soooo, cancer research, neurodegeneration research and more is possible with this model system.
No need for FOMO at #KillfishCon! Virtual registration still open: mdibl.org/conference/a...
September 26, 2026 at 11:28 AM
No need for FOMO at #KillfishCon! Virtual registration still open: mdibl.org/conference/a...
Congrats on the preprint! Are you going to the #killifish conference at @mdibl.org? bsky.app/profile/mdib... 🧪
Next week! 2026 African Turquoise Killifish Conference at MDI Bio Lab
The conference starts October 1, hybrid option still open — register now!
https://mdibl.org/conference/atk-2026/
The conference starts October 1, hybrid option still open — register now!
https://mdibl.org/conference/atk-2026/
September 26, 2026 at 11:26 AM
Congrats on the preprint! Are you going to the #killifish conference at @mdibl.org? bsky.app/profile/mdib... 🧪
Very cool #killifish work from @labmoons.bsky.social 🐠
Our #preprint out on @biorxiv-neursci.bsky.social! 🥳🥳
Using the #killifish optic nerve, we show that #aging alone is sufficient to trigger the emergence of #interferon-responsive #oligodendrocytes, a cell state shared with neurodegenerative and demyelinating diseases.
www.biorxiv.org/content/10.6...
Using the #killifish optic nerve, we show that #aging alone is sufficient to trigger the emergence of #interferon-responsive #oligodendrocytes, a cell state shared with neurodegenerative and demyelinating diseases.
www.biorxiv.org/content/10.6...
www.biorxiv.org
September 26, 2026 at 10:03 AM
Very cool #killifish work from @labmoons.bsky.social 🐠
Our #preprint out on @biorxiv-neursci.bsky.social! 🥳🥳
Using the #killifish optic nerve, we show that #aging alone is sufficient to trigger the emergence of #interferon-responsive #oligodendrocytes, a cell state shared with neurodegenerative and demyelinating diseases.
www.biorxiv.org/content/10.6...
Using the #killifish optic nerve, we show that #aging alone is sufficient to trigger the emergence of #interferon-responsive #oligodendrocytes, a cell state shared with neurodegenerative and demyelinating diseases.
www.biorxiv.org/content/10.6...
www.biorxiv.org
September 26, 2026 at 9:04 AM
Our #preprint out on @biorxiv-neursci.bsky.social! 🥳🥳
Using the #killifish optic nerve, we show that #aging alone is sufficient to trigger the emergence of #interferon-responsive #oligodendrocytes, a cell state shared with neurodegenerative and demyelinating diseases.
www.biorxiv.org/content/10.6...
Using the #killifish optic nerve, we show that #aging alone is sufficient to trigger the emergence of #interferon-responsive #oligodendrocytes, a cell state shared with neurodegenerative and demyelinating diseases.
www.biorxiv.org/content/10.6...
Loss of killifish cGAS attenuates age-related signatures but does not affect organismal life span
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Loss of killifish cGAS attenuates age-related signatures but does not affect organismal life span - EMBO Reports
The cGAS/STING pathway is a central innate immune signaling pathway responsive to cytosolic DNA. Chronic activation of this pathway promotes numerous age-related pathologies, but its impact on lifespa...
link.springer.com
September 25, 2026 at 6:23 PM
Loss of killifish cGAS attenuates age-related signatures but does not affect organismal life span
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Last day to register!!!
#Zebrafish #Gar #Killifish #Medaka #Stickleback #Xiphophorus #Lamprey #Xenopus #Cephalopod #Squid #Hydra #Aplysia #Nematostella #Tunicate #SeaUrchin #Planarian #Ctenophore #Ciona #Echinoderm #Aiptasia #Coral #ComparativeBiology
#Zebrafish #Gar #Killifish #Medaka #Stickleback #Xiphophorus #Lamprey #Xenopus #Cephalopod #Squid #Hydra #Aplysia #Nematostella #Tunicate #SeaUrchin #Planarian #Ctenophore #Ciona #Echinoderm #Aiptasia #Coral #ComparativeBiology
🗓️ AQMHD 2026 reminder: Registration closes THIS FRIDAY, Sept. 25 at 6:00 PM!
Planning to join us Oct. 17–21 at the Marine Biological Laboratory in Woods Hole? Now is the time to register!
aqmhd.org
🧵 1/3
Planning to join us Oct. 17–21 at the Marine Biological Laboratory in Woods Hole? Now is the time to register!
aqmhd.org
🧵 1/3
AQMHD 2026 | Aquatic Models of Human Disease
12th Aquatic Models of Human Disease Conference, October 17–21, 2026, Marine Biological Laboratory, Woods Hole, MA
aqmhd.org
September 25, 2026 at 2:15 PM
Epiplatys fasciolatus zimiensis - Zimi Lined KillifishEpiplatys fasciolatus zimiensis, also known as the Zimi Lined Killifish, is a fascinating freshwater fish species that captures the attention of aquarium enthusiasts and researchers alike. Originating from the Niger Delta region in Nigeria, this
Epiplatys fasciolatus zimiensis – Zimi Lined Killifish
Epiplatys fasciolatus zimiensis, also known as the Zimi Lined Killifish, is a fascinating freshwater fish species that captures the attention of aquarium enthusiasts and researchers alike. Originating from the Niger Delta region in Nigeria, this small but colorful fish has a storied past. Originally
killifishbreeding.com
September 24, 2026 at 6:01 PM
Epiplatys fasciolatus zimiensis - Zimi Lined KillifishEpiplatys fasciolatus zimiensis, also known as the Zimi Lined Killifish, is a fascinating freshwater fish species that captures the attention of aquarium enthusiasts and researchers alike. Originating from the Niger Delta region in Nigeria, this
nooo goldfishie get uppp 💔
I found it funny that he called him a killifish bc those are usually very vibrant and colorful but they get pale spots when stressed or sick :(
also gave riddle red streaks bc it looked tuff
#florid #riddlerosehearts #floydleech #twst #twistedwonderland #twstflorid
I found it funny that he called him a killifish bc those are usually very vibrant and colorful but they get pale spots when stressed or sick :(
also gave riddle red streaks bc it looked tuff
#florid #riddlerosehearts #floydleech #twst #twistedwonderland #twstflorid
September 24, 2026 at 11:02 AM
nooo goldfishie get uppp 💔
I found it funny that he called him a killifish bc those are usually very vibrant and colorful but they get pale spots when stressed or sick :(
also gave riddle red streaks bc it looked tuff
#florid #riddlerosehearts #floydleech #twst #twistedwonderland #twstflorid
I found it funny that he called him a killifish bc those are usually very vibrant and colorful but they get pale spots when stressed or sick :(
also gave riddle red streaks bc it looked tuff
#florid #riddlerosehearts #floydleech #twst #twistedwonderland #twstflorid
Aplocheilichthys scheeli - Scheel's KillifishIntroduction Aplocheilichthys scheeli: This paragraph will serve as the introduction to the topic. The purpose of this paragraph is to provide a brief overview and background information on the subject matter. It will set the context for the subsequent se
Aplocheilichthys scheeli – Scheel’s Killifish
Introduction Aplocheilichthys scheeli: This paragraph will serve as the introduction to the topic. The purpose of this paragraph is to provide a brief overview and background information on the subject matter. It will set the context for the subsequent sections and outline the main points to be disc
killifishbreeding.com
September 24, 2026 at 10:00 AM
Aplocheilichthys scheeli - Scheel's KillifishIntroduction Aplocheilichthys scheeli: This paragraph will serve as the introduction to the topic. The purpose of this paragraph is to provide a brief overview and background information on the subject matter. It will set the context for the subsequent se
Cynolebias leptocephalus - Slender Seasonal KillifishCynolebias leptocephalus, commonly known as the Slender Seasonal Killifish, is a fascinating species that captures the attention of fish enthusiasts worldwide. Residing in the rivers and wetlands of South America, this small fish has a unique char
Cynolebias leptocephalus – Slender Seasonal Killifish
Cynolebias leptocephalus, commonly known as the Slender Seasonal Killifish, is a fascinating species that captures the attention of fish enthusiasts worldwide. Residing in the rivers and wetlands of South America, this small fish has a unique characteristic that sets it apart from other species – it
killifishbreeding.com
September 24, 2026 at 2:02 AM
Cynolebias leptocephalus - Slender Seasonal KillifishCynolebias leptocephalus, commonly known as the Slender Seasonal Killifish, is a fascinating species that captures the attention of fish enthusiasts worldwide. Residing in the rivers and wetlands of South America, this small fish has a unique char
Cynolebias heloplitesIntroduction: Cynolebias heloplites, commonly known as the heloplites killifish, is a captivating and relatively lesser-known species of killifish found in South America. These freshwater fish belong to the family Rivulidae and are known for their striking appearance and unique
Cynolebias heloplites
Introduction: Cynolebias heloplites, commonly known as the heloplites killifish, is a captivating and relatively lesser-known species of killifish found in South America. These freshwater fish belong to the family Rivulidae and are known for their striking appearance and unique behavioral characteri
killifishbreeding.com
September 23, 2026 at 6:00 PM
Cynolebias heloplitesIntroduction: Cynolebias heloplites, commonly known as the heloplites killifish, is a captivating and relatively lesser-known species of killifish found in South America. These freshwater fish belong to the family Rivulidae and are known for their striking appearance and unique
I hate that all these species being discovered are already endangered.... it's disheartening.
Newly discovered orange killifish in the Brazilian Amazon may already be endangered
Researchers have discovered a new species of brilliantly colored fish from a network of forest streams in the Brazilian Amazon and have already recommended it for listing as Endangered because of the ...
phys.org
September 23, 2026 at 2:56 PM
I hate that all these species being discovered are already endangered.... it's disheartening.
Only 2 days left to join us in MBL!
#Zebrafish #Gar #Killifish #Medaka #Stickleback #Xiphophorus #Lamprey #Xenopus #Cephalopod #Squid #Hydra #Aplysia #Nematostella #Tunicate #SeaUrchin #Planarian #Ctenophore #Ciona #Echinoderm #Aiptasia #Coral #ComparativeBiology
#Zebrafish #Gar #Killifish #Medaka #Stickleback #Xiphophorus #Lamprey #Xenopus #Cephalopod #Squid #Hydra #Aplysia #Nematostella #Tunicate #SeaUrchin #Planarian #Ctenophore #Ciona #Echinoderm #Aiptasia #Coral #ComparativeBiology
🗓️ AQMHD 2026 reminder: Registration closes THIS FRIDAY, Sept. 25 at 6:00 PM!
Planning to join us Oct. 17–21 at the Marine Biological Laboratory in Woods Hole? Now is the time to register!
aqmhd.org
🧵 1/3
Planning to join us Oct. 17–21 at the Marine Biological Laboratory in Woods Hole? Now is the time to register!
aqmhd.org
🧵 1/3
AQMHD 2026 | Aquatic Models of Human Disease
12th Aquatic Models of Human Disease Conference, October 17–21, 2026, Marine Biological Laboratory, Woods Hole, MA
aqmhd.org
September 23, 2026 at 2:15 PM
Only 2 days left to join us in MBL!
#Zebrafish #Gar #Killifish #Medaka #Stickleback #Xiphophorus #Lamprey #Xenopus #Cephalopod #Squid #Hydra #Aplysia #Nematostella #Tunicate #SeaUrchin #Planarian #Ctenophore #Ciona #Echinoderm #Aiptasia #Coral #ComparativeBiology
#Zebrafish #Gar #Killifish #Medaka #Stickleback #Xiphophorus #Lamprey #Xenopus #Cephalopod #Squid #Hydra #Aplysia #Nematostella #Tunicate #SeaUrchin #Planarian #Ctenophore #Ciona #Echinoderm #Aiptasia #Coral #ComparativeBiology
Next week! 2026 African Turquoise Killifish Conference at MDI Bio Lab
The conference starts October 1, hybrid option still open — register now!
https://mdibl.org/conference/atk-2026/
The conference starts October 1, hybrid option still open — register now!
https://mdibl.org/conference/atk-2026/
September 23, 2026 at 2:00 PM
Next week! 2026 African Turquoise Killifish Conference at MDI Bio Lab
The conference starts October 1, hybrid option still open — register now!
https://mdibl.org/conference/atk-2026/
The conference starts October 1, hybrid option still open — register now!
https://mdibl.org/conference/atk-2026/
Aplocheilichthys kassenjiensis - Kassenji KillifishAplocheilichthys kassenjiensis, commonly known as the Kassenji Killifish, is a remarkable species of fish that captures attention with its vivid colors and unique features. Native to the Kassenji River in the Democratic Republic of Congo, this small
Aplocheilichthys kassenjiensis – Kassenji Killifish
Aplocheilichthys kassenjiensis, commonly known as the Kassenji Killifish, is a remarkable species of fish that captures attention with its vivid colors and unique features. Native to the Kassenji River in the Democratic Republic of Congo, this small freshwater fish has a rich history rooted in the w
killifishbreeding.com
September 23, 2026 at 10:00 AM
Aplocheilichthys kassenjiensis - Kassenji KillifishAplocheilichthys kassenjiensis, commonly known as the Kassenji Killifish, is a remarkable species of fish that captures attention with its vivid colors and unique features. Native to the Kassenji River in the Democratic Republic of Congo, this small
Aphanius mentoIntroduction Aphanius mento, commonly known as the Mento Killifish, stands out as a remarkable and lesser-known gem. This small yet striking fish is a member of the Aphanius genus, which includes various species known for their vibrant colors and interesting behaviors. In this comprehe
Aphanius mento
Introduction Aphanius mento, commonly known as the Mento Killifish, stands out as a remarkable and lesser-known gem. This small yet striking fish is a member of the Aphanius genus, which includes various species known for their vibrant colors and interesting behaviors. In this comprehensive article,
killifishbreeding.com
September 23, 2026 at 2:02 AM
Aphanius mentoIntroduction Aphanius mento, commonly known as the Mento Killifish, stands out as a remarkable and lesser-known gem. This small yet striking fish is a member of the Aphanius genus, which includes various species known for their vibrant colors and interesting behaviors. In this comprehe
#ILLOfTheDay "Noninvasive Ejaculate Collection from the African Turquoise Killifish Nothobranchius furzeri"
Truly the world is full of things
Truly the world is full of things
September 22, 2026 at 2:47 PM
#ILLOfTheDay "Noninvasive Ejaculate Collection from the African Turquoise Killifish Nothobranchius furzeri"
Truly the world is full of things
Truly the world is full of things
Laimosemion laranja is a newly described orange-patterned killifish known from only three forest pools in the Brazilian Amazon. Its estimated range is 25 square kilometers. doi.org/hckdc9
Newly discovered orange killifish in the Brazilian Amazon may already be endangered
Researchers have discovered a new species of brilliantly colored fish from a network of forest streams in the Brazilian Amazon and have already recommended it for listing as Endangered because of the pressures facing its only known home.
phys.org
September 22, 2026 at 2:20 PM
Laimosemion laranja is a newly described orange-patterned killifish known from only three forest pools in the Brazilian Amazon. Its estimated range is 25 square kilometers. doi.org/hckdc9