#PDE4DIP is identified as a driver of #LeftVentricularNoncompaction; its overexpression disrupts #cardiomyocyte polarity and energy metabolism, while knockdown restores #ATP and migration, highlighting new therapeutic targets for LVNC.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
January 8, 2026 at 12:45 AM
#PDE4DIP is identified as a driver of #LeftVentricularNoncompaction; its overexpression disrupts #cardiomyocyte polarity and energy metabolism, while knockdown restores #ATP and migration, highlighting new therapeutic targets for LVNC.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
#PDE4DIP activation plays a critical role in #LeftVentricularNoncompaction development by regulating #cellpolarity, skeleton, and energy metabolism via the Rho-ROCK pathway, thereby offering potential targets and therapeutic strategies. #medsky
#OpenAccess:
#OpenAccess:
www.sciencedirect.com
July 4, 2025 at 5:56 PM
#PDE4DIP activation plays a critical role in #LeftVentricularNoncompaction development by regulating #cellpolarity, skeleton, and energy metabolism via the Rho-ROCK pathway, thereby offering potential targets and therapeutic strategies. #medsky
#OpenAccess:
#OpenAccess:
This study identifies #PDE4DIP as a key player in #LeftVentricularNoncompaction development by regulating #cellpolarity, skeleton, and energy metabolism via the Rho-ROCK pathway. #LVNC
Dysfunction of PDE4DIP contributes to LVNC development by regulating cell polarity, skeleton ec1
This study demonstrates that dysfunction of PDE4DIP contributes to the development of left ventricular non-compaction (LVNC) cardiomyopathy by disrupting cel...
youtube.com
June 25, 2025 at 5:18 AM
This study identifies #PDE4DIP as a key player in #LeftVentricularNoncompaction development by regulating #cellpolarity, skeleton, and energy metabolism via the Rho-ROCK pathway. #LVNC