Are you working on natural products? We’ve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration
Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag
academic.oup.com
December 10, 2024 at 8:05 AM
Are you working on natural products? We’ve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...
Have you ever used a #bioinformatics #database and were frustrated by its lack of coverage? Did you ever think about starting your own resource? We just published a new strategy for community-driven #biocuration, based on our experiences with the #MIBiG database (1/8)! doi.org/10.1093/bib/...
Strategies for community-sourced biocuration in bioinformatics: a case study on MIBiG 4.0
Abstract. Biocuration is essential to transform molecular sequence data into standardized, machine-readable resources. Such curated datasets enable compara
doi.org
December 11, 2025 at 7:19 PM
Have you ever used a #bioinformatics #database and were frustrated by its lack of coverage? Did you ever think about starting your own resource? We just published a new strategy for community-driven #biocuration, based on our experiences with the #MIBiG database (1/8)! doi.org/10.1093/bib/...
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration academic.oup.com/nar/advance-...
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration
Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag
academic.oup.com
December 10, 2024 at 12:50 PM
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration academic.oup.com/nar/advance-...
Thanks to Catarina Loureiro whole gave a wonderful talk for the new antismash, big scape and MiBIG decorations.
January 11, 2025 at 3:37 AM
Thanks to Catarina Loureiro whole gave a wonderful talk for the new antismash, big scape and MiBIG decorations.
The MIBiG 5.0 Annotathon is coming soon, and registration is now open!
🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise.
Register here 👉 forms.gle/C1cWcLHtrjT2...
🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise.
Register here 👉 forms.gle/C1cWcLHtrjT2...
February 20, 2026 at 4:06 AM
The MIBiG 5.0 Annotathon is coming soon, and registration is now open!
🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise.
Register here 👉 forms.gle/C1cWcLHtrjT2...
🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise.
Register here 👉 forms.gle/C1cWcLHtrjT2...
Many thanks to all contributors that make #MIBiG a true collaborative #OpenScience resource. And of course many thanks to @mmzdouc.bsky.social, @kblin.bsky.social and @marnixmedema.bsky.social for coordinating this huge effort. academic.oup.com/nar/advance-...
December 10, 2024 at 5:27 PM
Many thanks to all contributors that make #MIBiG a true collaborative #OpenScience resource. And of course many thanks to @mmzdouc.bsky.social, @kblin.bsky.social and @marnixmedema.bsky.social for coordinating this huge effort. academic.oup.com/nar/advance-...
Grab the chance to already pre-register for the MIBiG 5.0 annotathons that we plan to organize in spring 2026!
Speaking of MIBiG hackathons: iteration 5.0 it is planned for spring 2026 and registrations are open! Please sign up if you are interested and feel free to share with your colleagues! (7/8) forms.gle/JKsf3XL3d1XN...
MIBiG 5.0 Annotathons Registration Form
Planned for spring 2026
forms.gle
December 13, 2025 at 7:44 AM
Grab the chance to already pre-register for the MIBiG 5.0 annotathons that we plan to organize in spring 2026!
Check out the publication on MIBiG 4.0 here: academic.oup.com/nar/article/...
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration
Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag
academic.oup.com
February 20, 2026 at 4:11 AM
Check out the publication on MIBiG 4.0 here: academic.oup.com/nar/article/...
Nice to see the MIBiG 4.0 published in #NAR with so many from #LeidenBiology being involved in this massive community approach for annotating biosynthetic gene clusters
Superb coordination by @mmzdouc.bsky.social @kblin.bsky.social @tilmweber.bsky.social @marnixmedema.bsky.social 🙏
Superb coordination by @mmzdouc.bsky.social @kblin.bsky.social @tilmweber.bsky.social @marnixmedema.bsky.social 🙏
December 10, 2024 at 8:37 AM
Nice to see the MIBiG 4.0 published in #NAR with so many from #LeidenBiology being involved in this massive community approach for annotating biosynthetic gene clusters
Superb coordination by @mmzdouc.bsky.social @kblin.bsky.social @tilmweber.bsky.social @marnixmedema.bsky.social 🙏
Superb coordination by @mmzdouc.bsky.social @kblin.bsky.social @tilmweber.bsky.social @marnixmedema.bsky.social 🙏
The #NPLinker eScience #workshop 2025 started today with a round of introductions & theory and hands-on of #genome #mining and #gene cluster grouping led by @tilmweber.bsky.social & Arjan Draisma! 😎 The first NPLinker data type covered!
#antiSMASH #MIBiG #BiGSCAPE
Wageningen University & Research
#antiSMASH #MIBiG #BiGSCAPE
Wageningen University & Research
March 25, 2025 at 10:38 PM
The #NPLinker eScience #workshop 2025 started today with a round of introductions & theory and hands-on of #genome #mining and #gene cluster grouping led by @tilmweber.bsky.social & Arjan Draisma! 😎 The first NPLinker data type covered!
#antiSMASH #MIBiG #BiGSCAPE
Wageningen University & Research
#antiSMASH #MIBiG #BiGSCAPE
Wageningen University & Research
And the perspectives article about the strategies and lessons learned from the MIBiG 4.0 Annotathon here: academic.oup.com/bib/article/...
Strategies for community-sourced biocuration in bioinformatics: a case study on MIBiG 4.0
Abstract. Biocuration is essential to transform molecular sequence data into standardized, machine-readable resources. Such curated datasets enable compara
urldefense.com
February 20, 2026 at 4:13 AM
And the perspectives article about the strategies and lessons learned from the MIBiG 4.0 Annotathon here: academic.oup.com/bib/article/...
Great and fun community initiative to expand the number of annotated biosynthetic gene clusters in MIBiG!
The MIBiG 5.0 Annotathon is coming soon, and registration is now open!
🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise.
Register here 👉 forms.gle/C1cWcLHtrjT2...
🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise.
Register here 👉 forms.gle/C1cWcLHtrjT2...
February 20, 2026 at 6:34 AM
Great and fun community initiative to expand the number of annotated biosynthetic gene clusters in MIBiG!
Fantastic #community #effort for #naturalproducts #discovery through #genome #mining! 😎 Great leadership by Mitja Zdouc @mmzdouc.bsky.social to get everyone on board and MIBiG 4.0 out 👏 #ProudPI
Are you working on natural products? We’ve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration
Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag
academic.oup.com
December 10, 2024 at 11:39 AM
Fantastic #community #effort for #naturalproducts #discovery through #genome #mining! 😎 Great leadership by Mitja Zdouc @mmzdouc.bsky.social to get everyone on board and MIBiG 4.0 out 👏 #ProudPI
Make sure to join us in the MIBiG Annotathons! The MITE database (mite.bioinformatics.nl) will join the efforts! If you are interested in tailoring enzymes/maturases, make sure to join us!
February 20, 2026 at 9:05 AM
Make sure to join us in the MIBiG Annotathons! The MITE database (mite.bioinformatics.nl) will join the efforts! If you are interested in tailoring enzymes/maturases, make sure to join us!
Speaking of MIBiG hackathons: iteration 5.0 it is planned for spring 2026 and registrations are open! Please sign up if you are interested and feel free to share with your colleagues! (7/8) forms.gle/JKsf3XL3d1XN...
MIBiG 5.0 Annotathons Registration Form
Planned for spring 2026
forms.gle
December 11, 2025 at 7:19 PM
Speaking of MIBiG hackathons: iteration 5.0 it is planned for spring 2026 and registrations are open! Please sign up if you are interested and feel free to share with your colleagues! (7/8) forms.gle/JKsf3XL3d1XN...
MIBiG 4.0 is out! Thanks @mmzdouc.bsky.social and @kblin.bsky.social for spearheading this huge effort, and to the entire community for investing time in extending this resource on BGCs of known function.
Are you working on natural products? We’ve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration
Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag
academic.oup.com
December 10, 2024 at 9:24 AM
MIBiG 4.0 is out! Thanks @mmzdouc.bsky.social and @kblin.bsky.social for spearheading this huge effort, and to the entire community for investing time in extending this resource on BGCs of known function.
📊 In 2024, the MIBiG 4.0 Annotathon brought together 267 participants from around the world and resulted in a 22% expansion of deposited BGCs. Researchers at all career stages are encouraged to participate. If you’re interested in helping shape the next release of MIBiG, we invite you to join us.
February 20, 2026 at 4:07 AM
📊 In 2024, the MIBiG 4.0 Annotathon brought together 267 participants from around the world and resulted in a 22% expansion of deposited BGCs. Researchers at all career stages are encouraged to participate. If you’re interested in helping shape the next release of MIBiG, we invite you to join us.
Thanks to @nicoleeavalon.bsky.social for leading the charge. Looking forward to another round of MIBiG annotathons
The MIBiG 5.0 Annotathon is coming soon, and registration is now open!
🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise.
Register here 👉 forms.gle/C1cWcLHtrjT2...
🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise.
Register here 👉 forms.gle/C1cWcLHtrjT2...
February 20, 2026 at 6:57 AM
Thanks to @nicoleeavalon.bsky.social for leading the charge. Looking forward to another round of MIBiG annotathons
I'll be coordinating the efforts along with others on the MIBiG 5.0 Annotathon team including: @marnixmedema.bsky.social, @TilmannWebber, @kblin.bsky.social, @mmzdouc.bsky.social, @jjjvanderhooft.bsky.social, @BarbaraTerlouw, and @ArjanDraisma.
February 20, 2026 at 4:10 AM
I'll be coordinating the efforts along with others on the MIBiG 5.0 Annotathon team including: @marnixmedema.bsky.social, @TilmannWebber, @kblin.bsky.social, @mmzdouc.bsky.social, @jjjvanderhooft.bsky.social, @BarbaraTerlouw, and @ArjanDraisma.
Great opportunity to contribute to MIBiG!
Speaking of MIBiG hackathons: iteration 5.0 it is planned for spring 2026 and registrations are open! Please sign up if you are interested and feel free to share with your colleagues! (7/8) forms.gle/JKsf3XL3d1XN...
MIBiG 5.0 Annotathons Registration Form
Planned for spring 2026
forms.gle
December 12, 2025 at 3:11 PM
Great opportunity to contribute to MIBiG!
MITE can be queried in various ways to get information about tailoring enzymes, their pathways, and associated organisms. Its already being used by @antismash.bsky.social and MIBiG, and we foresee its use in machine learning applications for enzyme reaction prediction and classification!
September 27, 2025 at 9:11 AM
MITE can be queried in various ways to get information about tailoring enzymes, their pathways, and associated organisms. Its already being used by @antismash.bsky.social and MIBiG, and we foresee its use in machine learning applications for enzyme reaction prediction and classification!
The MITE database is a curated, crowd-sourced, and expert-reviewed database of tailoring enzymes, capturing catalytic reactions, substrate specificities, genomic context, and cross-references to existing resources (e.g. MIBiG, Rhea, UniProt).
September 27, 2025 at 9:11 AM
The MITE database is a curated, crowd-sourced, and expert-reviewed database of tailoring enzymes, capturing catalytic reactions, substrate specificities, genomic context, and cross-references to existing resources (e.g. MIBiG, Rhea, UniProt).
INVITATION We are starting a new round of online community annotathons to populate v4.0 of the MIBiG repository with high-quality data. If you have relevant expertise in natural product genomics or chemistry, please participate! Please register here: forms.gle/LJR9uRTCyLg7...
January 22, 2024 at 11:38 AM
INVITATION We are starting a new round of online community annotathons to populate v4.0 of the MIBiG repository with high-quality data. If you have relevant expertise in natural product genomics or chemistry, please participate! Please register here: forms.gle/LJR9uRTCyLg7...