A microbiome gut-brain pathway influenced by intestinal metabolites, innate immune responses, vagal nerve signaling and hippocampal memory encoding, impacts the rate of cognitive decline. Many potential points of intervention are described.
#Science 🧪
#Science 🧪
Intestinal interoceptive dysfunction drives age-associated cognitive decline - Nature
Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting this g...
www.nature.com
March 14, 2026 at 7:30 PM
A microbiome gut-brain pathway influenced by intestinal metabolites, innate immune responses, vagal nerve signaling and hippocampal memory encoding, impacts the rate of cognitive decline. Many potential points of intervention are described.
#Science 🧪
#Science 🧪
Estimates of microbiome heritability across hosts.
#Microbiome #NatureMicrobiology #BioSky #SciSky 🧪
www.nature.com/articles/s41...
#Microbiome #NatureMicrobiology #BioSky #SciSky 🧪
www.nature.com/articles/s41...
Estimates of microbiome heritability across hosts - Nature Microbiology
In this Perspective, Morris and Bohannan discuss heritability of microbiome-mediated traits across hosts and future research questions with implications for animal and plant breeding.
www.nature.com
November 16, 2024 at 11:18 AM
Estimates of microbiome heritability across hosts.
#Microbiome #NatureMicrobiology #BioSky #SciSky 🧪
www.nature.com/articles/s41...
#Microbiome #NatureMicrobiology #BioSky #SciSky 🧪
www.nature.com/articles/s41...
This one surely has something on offer for every one: In this cross-sectional mediation analysis, the "effects" of soft drink consumption on depression were "mediated" by abundance of Eggerthela in the gut microbiome.
This was sent to me via dm and now you all got to suffer as well.
This was sent to me via dm and now you all got to suffer as well.
Soft Drink Consumption and Depression Mediated by Gut Microbiome Alterations
This cohort study examines the association between soft drink consumption and major depressive disorder diagnosis and severity and whether this association is mediated by changes in the gut microbiota...
jamanetwork.com
November 9, 2025 at 7:19 AM
This one surely has something on offer for every one: In this cross-sectional mediation analysis, the "effects" of soft drink consumption on depression were "mediated" by abundance of Eggerthela in the gut microbiome.
This was sent to me via dm and now you all got to suffer as well.
This was sent to me via dm and now you all got to suffer as well.
New perspective with a comprehensive overview of the microbiome heritability concept
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Estimates of microbiome heritability across hosts - Nature Microbiology
In this Perspective, Morris and Bohannan discuss heritability of microbiome-mediated traits across hosts and future research questions with implications for animal and plant breeding.
www.nature.com
November 19, 2024 at 2:25 AM
New perspective with a comprehensive overview of the microbiome heritability concept
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Thrilled to share that I got the @vetenskapsradet.bsky.social Starting Grant to lead the #HOTGUT project at @biologylu.bsky.social to explore microbiome-mediated thermal resilience in birds 🐦🦠🌡️
#HOTGUT will be in close collaboration with @cyanistesnord.bsky.social - open #postdoc position soon!
#HOTGUT will be in close collaboration with @cyanistesnord.bsky.social - open #postdoc position soon!
September 28, 2026 at 4:08 PM
Thrilled to share that I got the @vetenskapsradet.bsky.social Starting Grant to lead the #HOTGUT project at @biologylu.bsky.social to explore microbiome-mediated thermal resilience in birds 🐦🦠🌡️
#HOTGUT will be in close collaboration with @cyanistesnord.bsky.social - open #postdoc position soon!
#HOTGUT will be in close collaboration with @cyanistesnord.bsky.social - open #postdoc position soon!
🧬 New Article | Recombination-Mediated Gene-Specific Sweeps in the Human Gut Microbiome
How does the human gut microbiome rapidly adapt to changing environmental pressures?
📖 Read the full article:
www.oaepublish.com/articles/mrr...
How does the human gut microbiome rapidly adapt to changing environmental pressures?
📖 Read the full article:
www.oaepublish.com/articles/mrr...
Recombination-mediated gene-specific sweeps in motion across the human gut microbiome
www.oaepublish.com
September 30, 2026 at 9:07 AM
🧬 New Article | Recombination-Mediated Gene-Specific Sweeps in the Human Gut Microbiome
How does the human gut microbiome rapidly adapt to changing environmental pressures?
📖 Read the full article:
www.oaepublish.com/articles/mrr...
How does the human gut microbiome rapidly adapt to changing environmental pressures?
📖 Read the full article:
www.oaepublish.com/articles/mrr...
Read my latest #research with Brendan Bohannan on the #heritability of the #microbiome, published with @natureportfolio.bsky.social in #NatureMicrobiology Read here: rdcu.be/d0h31 #Biosky #Microsky #Scisky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Estimates of microbiome heritability across hosts - Nature Microbiology
In this Perspective, Morris and Bohannan discuss heritability of microbiome-mediated traits across hosts and future research questions with implications for animal and plant breeding.
www.nature.com
November 20, 2024 at 1:28 PM
Read my latest #research with Brendan Bohannan on the #heritability of the #microbiome, published with @natureportfolio.bsky.social in #NatureMicrobiology Read here: rdcu.be/d0h31 #Biosky #Microsky #Scisky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
JCI - The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17 www.jci.org/articles/vie...
May 15, 2025 at 10:57 AM
JCI - The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17 www.jci.org/articles/vie...
Weaning drives microbiome-mediated epigenetic regulation to shape immune memory in mice @natmicrobiol.nature.com @bcmfromthelabs.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 19, 2026 at 8:36 PM
Weaning drives microbiome-mediated epigenetic regulation to shape immune memory in mice @natmicrobiol.nature.com @bcmfromthelabs.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
#NewResearch
Systematic analyses and machine learning coupled with in vitro and in vivo validation link gut microbiome-mediated transformation of dietary phytonutrients to health outcomes
#MicroSky #MicrobiomeSky 🦠🌱
www.nature.com/articles/s41...
Systematic analyses and machine learning coupled with in vitro and in vivo validation link gut microbiome-mediated transformation of dietary phytonutrients to health outcomes
#MicroSky #MicrobiomeSky 🦠🌱
www.nature.com/articles/s41...
Gut microbiome-mediated transformation of dietary phytonutrients is associated with health outcomes - Nature Microbiology
Systematic analysis and machine learning coupled with in vitro and in vivo validation link gut microbiome-mediated transformation of dietary phytonutrients to health outcomes.
www.nature.com
December 3, 2025 at 5:13 PM
#NewResearch
Systematic analyses and machine learning coupled with in vitro and in vivo validation link gut microbiome-mediated transformation of dietary phytonutrients to health outcomes
#MicroSky #MicrobiomeSky 🦠🌱
www.nature.com/articles/s41...
Systematic analyses and machine learning coupled with in vitro and in vivo validation link gut microbiome-mediated transformation of dietary phytonutrients to health outcomes
#MicroSky #MicrobiomeSky 🦠🌱
www.nature.com/articles/s41...
If you missed my recent #MVIF talk on our precision nutrition work, you can catch it here youtu.be/L1VutD02lu8?...
Thanks to the organizers for providing these virtual events for free to the microbiome community! 🎉
@microbiomevif.bsky.social
Thanks to the organizers for providing these virtual events for free to the microbiome community! 🎉
@microbiomevif.bsky.social
Sean Gibbons - My Digital Gut: a tool set for microbiome-mediated precision nutrition | S04 MVIF34
YouTube video by Microbiome Virtual International Forum
youtu.be
December 9, 2024 at 5:36 PM
If you missed my recent #MVIF talk on our precision nutrition work, you can catch it here youtu.be/L1VutD02lu8?...
Thanks to the organizers for providing these virtual events for free to the microbiome community! 🎉
@microbiomevif.bsky.social
Thanks to the organizers for providing these virtual events for free to the microbiome community! 🎉
@microbiomevif.bsky.social
Treating emergent traits of the microbiome like quantitative genetic traits of the host reveals how environmentally acquired symbionts can contribute to hosts' adaptation
Quantitative genetics of microbiome-mediated traits
Microbiomes, the complex communities of microorganisms associated with multicellular hosts, play a vital role in shaping host traits and fitness. But how d
buff.ly
November 24, 2025 at 3:19 PM
Treating emergent traits of the microbiome like quantitative genetic traits of the host reveals how environmentally acquired symbionts can contribute to hosts' adaptation
#Seizures #Ketogenic #Diet #Gut #Microbiota #Microbiome
www.cell.com/cell/fulltex...
#SharedFacts #HealthScience
www.cell.com/cell/fulltex...
#SharedFacts #HealthScience
The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet
The beneficial effects of a ketogenic diet on epileptic seizures are mediated by the
gut microbiome through their modulation of hippocampal GABA/glutamate ratios.
www.cell.com
March 26, 2025 at 7:52 PM
updated preprint: Intriguingly, Arabidopsis responded with both, improved growth and enhanced defence to a maize-conditioned soil microbiome, and this dual microbiome feedbacks were mediated by priming of the defences. Credits to Katja Stengele et al.!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Benzoxazinoid-mediated microbiome feedbacks enhance Arabidopsis growth and defense
Plants modulate their surrounding microbiome via root exudates and this conditioned soil microbiome feeds back on the performance of the next generation of plants. How plants can perceive this altered...
www.biorxiv.org
August 29, 2025 at 6:45 PM
updated preprint: Intriguingly, Arabidopsis responded with both, improved growth and enhanced defence to a maize-conditioned soil microbiome, and this dual microbiome feedbacks were mediated by priming of the defences. Credits to Katja Stengele et al.!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The incomparable Zong roped @wvschaik.bsky.social and I into a comment for Nature Comms on microbiome mediated colonisation resistance to combat Klebsiella
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Microbiome-mediated colonization resistance to and countermeasures of Klebsiella pneumoniae - Nature Communications
Yang et al. summarize that Klebsiella pneumoniae affects infectious and non-infectious disease via gut colonization; commensals provide colonization resistance, but K. pneumoniae adapts via multiple m...
www.nature.com
February 19, 2026 at 9:01 AM
The incomparable Zong roped @wvschaik.bsky.social and I into a comment for Nature Comms on microbiome mediated colonisation resistance to combat Klebsiella
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Nature research paper: Long-read metagenomics reveals phage dynamics in the human gut microbiome
go.nature.com/44zgo1o
go.nature.com/44zgo1o
Long-read metagenomics reveals phage dynamics in the human gut microbiome - Nature
Complex prophage integration dynamics, including low-level induction, cross-family host range and transposase-mediated mobilization, challenge existing paradigms and deepen our understanding of phage–bacterial interactions in the human gut microbiome.
go.nature.com
November 28, 2025 at 11:52 AM
Nature research paper: Long-read metagenomics reveals phage dynamics in the human gut microbiome
go.nature.com/44zgo1o
go.nature.com/44zgo1o
Excited to share our last work on microbiome transmission and social interactions published on Nature!
The more people you interact with, the more similar your microbiome is.
www.nature.com/articles/s41...
The more people you interact with, the more similar your microbiome is.
www.nature.com/articles/s41...
Gut microbiome strain-sharing within isolated village social networks - Nature
An investigation into the relationship between network structure and gut microbiome composition among people living in 18 isolated Honduras villages reveals that strain-sharing can be mediated by...
www.nature.com
November 21, 2024 at 4:45 PM
Excited to share our last work on microbiome transmission and social interactions published on Nature!
The more people you interact with, the more similar your microbiome is.
www.nature.com/articles/s41...
The more people you interact with, the more similar your microbiome is.
www.nature.com/articles/s41...
Quantitative Genetics of Microbiome Mediated Traits https://www.biorxiv.org/content/10.1101/2024.12.16.628599v1
December 20, 2024 at 3:37 PM
Quantitative Genetics of Microbiome Mediated Traits https://www.biorxiv.org/content/10.1101/2024.12.16.628599v1
Great seminar from Kaili Fu from the Zimmermann group, who shared her postdoctoral work on gut microbiome-mediated drug-drug interactions in colorectal cancer treatment. Thanks, Kaili, for giving us a glimpse into this exciting work at the interface of microbiome research and cancer therapy!
July 22, 2026 at 1:15 PM
Great seminar from Kaili Fu from the Zimmermann group, who shared her postdoctoral work on gut microbiome-mediated drug-drug interactions in colorectal cancer treatment. Thanks, Kaili, for giving us a glimpse into this exciting work at the interface of microbiome research and cancer therapy!
Gut microbiome strain-sharing within isolated village social networks
More evidence of a sociobiome- cool paper from @nachristakis.bsky.social & colleagues
www.nature.com/articles/s41...
More evidence of a sociobiome- cool paper from @nachristakis.bsky.social & colleagues
www.nature.com/articles/s41...
Gut microbiome strain-sharing within isolated village social networks - Nature
An investigation into the relationship between network structure and gut microbiome composition among people living in 18 isolated Honduras villages reveals that strain-sharing can be mediated by...
www.nature.com
November 25, 2024 at 10:27 PM
Gut microbiome strain-sharing within isolated village social networks
More evidence of a sociobiome- cool paper from @nachristakis.bsky.social & colleagues
www.nature.com/articles/s41...
More evidence of a sociobiome- cool paper from @nachristakis.bsky.social & colleagues
www.nature.com/articles/s41...
New study: Benzoxazinoid‐mediated microbiome feedbacks enhance Arabidopsis growth and defence - Stengele - New Phytologist - Wiley Online Library nph.onlinelibrary.wiley.com/doi/10.1111/...
Benzoxazinoid‐mediated microbiome feedbacks enhance Arabidopsis growth and defence
Plants modulate their surrounding microbiome via root exudates and such conditioned soil microbiomes feed back on the performance of the next generation of plants. How plants perceive altered soil m...
nph.onlinelibrary.wiley.com
March 18, 2026 at 9:01 AM
New study: Benzoxazinoid‐mediated microbiome feedbacks enhance Arabidopsis growth and defence - Stengele - New Phytologist - Wiley Online Library nph.onlinelibrary.wiley.com/doi/10.1111/...
Remarkable study from Christoph Thaiss and colleagues demonstrating a lifespan impact of a microbiome-vagal-CNS pathway dysfunction of gut interoception
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Intestinal interoceptive dysfunction drives age-associated cognitive decline - Nature
Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting this g...
www.nature.com
March 11, 2026 at 9:32 PM
Remarkable study from Christoph Thaiss and colleagues demonstrating a lifespan impact of a microbiome-vagal-CNS pathway dysfunction of gut interoception
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Delighted to highlight new work by Kelly Jameson and colleagues showing that select microbial metabolites in the small intestinal lumen regulate vagal activity
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Select microbial metabolites in the small intestinal lumen regulates vagal activity via receptor-mediated signaling
Neuroscience; Microbiome
www.cell.com
January 29, 2025 at 9:28 PM
Delighted to highlight new work by Kelly Jameson and colleagues showing that select microbial metabolites in the small intestinal lumen regulate vagal activity
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Journal cover for the first time in my career!
We published a review article about microbiome-mediated plant disease resistance and its agricultural implications.
Hopefully, you can enjoy reading.
Open access
link.springer.com/article/10.1...
We published a review article about microbiome-mediated plant disease resistance and its agricultural implications.
Hopefully, you can enjoy reading.
Open access
link.springer.com/article/10.1...
January 8, 2025 at 3:31 AM
Journal cover for the first time in my career!
We published a review article about microbiome-mediated plant disease resistance and its agricultural implications.
Hopefully, you can enjoy reading.
Open access
link.springer.com/article/10.1...
We published a review article about microbiome-mediated plant disease resistance and its agricultural implications.
Hopefully, you can enjoy reading.
Open access
link.springer.com/article/10.1...
Bacterial DNA encapsidation by viruses and virus-like particles appears to be widespread in the microbiome with up to 5.4% of capsid-packaged DNA in the gut virome being of bacterial (non-prophage) origin.
www.biorxiv.org/content/10.1...
2/2
www.biorxiv.org/content/10.1...
2/2
Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
Here, we present a novel approach to study packaging and mobilisation of bacterial DNA in complex microbial communities, such as the human gut microbiome, by viral or virus-like capsids. Transducing b...
www.biorxiv.org
November 17, 2024 at 10:41 PM
Bacterial DNA encapsidation by viruses and virus-like particles appears to be widespread in the microbiome with up to 5.4% of capsid-packaged DNA in the gut virome being of bacterial (non-prophage) origin.
www.biorxiv.org/content/10.1...
2/2
www.biorxiv.org/content/10.1...
2/2