5. Microcirculation: besides its effects on macro-hemodynamics, D has been shown to improve microcirculation in patients with resuscitated septic shock & post-cardiac surgery
February 15, 2025 at 10:31 PM
5. Microcirculation: besides its effects on macro-hemodynamics, D has been shown to improve microcirculation in patients with resuscitated septic shock & post-cardiac surgery
🚨🧵by Zdenek Vrozina on XTwitter:
"An interesting and biologically plausible pilot study that provides a fairly strong signal that pediatric Long COVID may be associated with impaired microcirculation and increased arterial stiffness..."
19-tweet🧵
threadreaderapp.com/thread/20343...
"An interesting and biologically plausible pilot study that provides a fairly strong signal that pediatric Long COVID may be associated with impaired microcirculation and increased arterial stiffness..."
19-tweet🧵
threadreaderapp.com/thread/20343...
March 19, 2026 at 2:33 AM
🚨🧵by Zdenek Vrozina on XTwitter:
"An interesting and biologically plausible pilot study that provides a fairly strong signal that pediatric Long COVID may be associated with impaired microcirculation and increased arterial stiffness..."
19-tweet🧵
threadreaderapp.com/thread/20343...
"An interesting and biologically plausible pilot study that provides a fairly strong signal that pediatric Long COVID may be associated with impaired microcirculation and increased arterial stiffness..."
19-tweet🧵
threadreaderapp.com/thread/20343...
This matters because NETs are inflammatory and pro-clotting. Their sticky DNA–protein webs can stabilise microclots, making them harder to break down and disrupting microcirculation. 6/
November 17, 2025 at 12:25 PM
This matters because NETs are inflammatory and pro-clotting. Their sticky DNA–protein webs can stabilise microclots, making them harder to break down and disrupting microcirculation. 6/
1) 🇩🇪 Researchers from Munich tested microcirculation in the eyes of Long Covid patients.
They weren't interested in eyesight, but used the eye to study circulation and endothelial function in the brain. They call it a "accessible surrogate of cerebral microvascular function"
They weren't interested in eyesight, but used the eye to study circulation and endothelial function in the brain. They call it a "accessible surrogate of cerebral microvascular function"
February 1, 2026 at 9:05 AM
1) 🇩🇪 Researchers from Munich tested microcirculation in the eyes of Long Covid patients.
They weren't interested in eyesight, but used the eye to study circulation and endothelial function in the brain. They call it a "accessible surrogate of cerebral microvascular function"
They weren't interested in eyesight, but used the eye to study circulation and endothelial function in the brain. They call it a "accessible surrogate of cerebral microvascular function"
Erlangen researchers studied 150 people and found that Post-COVID patients showed impaired muscle deoxygenation during light exercise.
Fatigue was strongly linked to abnormal oxygen dynamics, hinting at disrupted microcirculation.
www.mdpi.com/2227-9059/13...
Fatigue was strongly linked to abnormal oxygen dynamics, hinting at disrupted microcirculation.
www.mdpi.com/2227-9059/13...
www.mdpi.com
June 11, 2025 at 3:09 PM
Erlangen researchers studied 150 people and found that Post-COVID patients showed impaired muscle deoxygenation during light exercise.
Fatigue was strongly linked to abnormal oxygen dynamics, hinting at disrupted microcirculation.
www.mdpi.com/2227-9059/13...
Fatigue was strongly linked to abnormal oxygen dynamics, hinting at disrupted microcirculation.
www.mdpi.com/2227-9059/13...
Did y’all know that COVID was found in clots in the coronary arteries?
Totally safe virus right… no problems living with this one at all…
#CovidIsNotOver
ccforum.biomedcentral.com/articles/10....
Totally safe virus right… no problems living with this one at all…
#CovidIsNotOver
ccforum.biomedcentral.com/articles/10....
SARS-COV-2 colonizes coronary thrombus and impairs heart microcirculation bed in asymptomatic SARS-CoV-2 positive subjects with acute myocardial infarction - Critical Care
Background The viral load of asymptomatic SAR-COV-2 positive (ASAP) persons has been equal to that of symptomatic patients. On the other hand, there are no reports of ST-elevation myocardial infarctio...
ccforum.biomedcentral.com
December 22, 2024 at 10:17 PM
Did y’all know that COVID was found in clots in the coronary arteries?
Totally safe virus right… no problems living with this one at all…
#CovidIsNotOver
ccforum.biomedcentral.com/articles/10....
Totally safe virus right… no problems living with this one at all…
#CovidIsNotOver
ccforum.biomedcentral.com/articles/10....
Nailfold Capillaroscopy:
Unveiling Fibrinoid Microclots and Microcirculation Dynamics
www.buzzsprout.com/2405788/epis...
helioxpodcast.substack.com/publish/post...
#MedicalResearch #ChronicIllness #BloodClots #LongCOVID #HealthScience #Microcirculation #HealthTech #Diagnostics #Science
Unveiling Fibrinoid Microclots and Microcirculation Dynamics
www.buzzsprout.com/2405788/epis...
helioxpodcast.substack.com/publish/post...
#MedicalResearch #ChronicIllness #BloodClots #LongCOVID #HealthScience #Microcirculation #HealthTech #Diagnostics #Science
July 21, 2025 at 5:05 PM
Nailfold Capillaroscopy:
Unveiling Fibrinoid Microclots and Microcirculation Dynamics
www.buzzsprout.com/2405788/epis...
helioxpodcast.substack.com/publish/post...
#MedicalResearch #ChronicIllness #BloodClots #LongCOVID #HealthScience #Microcirculation #HealthTech #Diagnostics #Science
Unveiling Fibrinoid Microclots and Microcirculation Dynamics
www.buzzsprout.com/2405788/epis...
helioxpodcast.substack.com/publish/post...
#MedicalResearch #ChronicIllness #BloodClots #LongCOVID #HealthScience #Microcirculation #HealthTech #Diagnostics #Science
Tongue-in-cheek study on why Rudolf's nose is red:
"Rudolph’s nose is red because it is richly supplied with red blood cells, comprises a highly dense microcirculation, and is anatomically and physiologically adapted for reindeer to carry out their flying duties for Santa Claus."
(📷: Kia K Hansen)
"Rudolph’s nose is red because it is richly supplied with red blood cells, comprises a highly dense microcirculation, and is anatomically and physiologically adapted for reindeer to carry out their flying duties for Santa Claus."
(📷: Kia K Hansen)
December 10, 2024 at 1:32 PM
Tongue-in-cheek study on why Rudolf's nose is red:
"Rudolph’s nose is red because it is richly supplied with red blood cells, comprises a highly dense microcirculation, and is anatomically and physiologically adapted for reindeer to carry out their flying duties for Santa Claus."
(📷: Kia K Hansen)
"Rudolph’s nose is red because it is richly supplied with red blood cells, comprises a highly dense microcirculation, and is anatomically and physiologically adapted for reindeer to carry out their flying duties for Santa Claus."
(📷: Kia K Hansen)
Just spent two incredible days at the 75th British Microcirculation and Vascular Biology Society (BMVBS) conference where I presented my poster on a novel lung endothelial GPCR shaping VEGF driven angiogenesis 🫁
Amazing science, inspiring people, and plenty of ideas to fuel my research 🧠🔥🧪
#BMVBS
Amazing science, inspiring people, and plenty of ideas to fuel my research 🧠🔥🧪
#BMVBS
July 5, 2025 at 7:14 AM
Just spent two incredible days at the 75th British Microcirculation and Vascular Biology Society (BMVBS) conference where I presented my poster on a novel lung endothelial GPCR shaping VEGF driven angiogenesis 🫁
Amazing science, inspiring people, and plenty of ideas to fuel my research 🧠🔥🧪
#BMVBS
Amazing science, inspiring people, and plenty of ideas to fuel my research 🧠🔥🧪
#BMVBS
Tomorrow is the 75th birthday of Brazilian cardiovascular physician Eliele Bouskela! She founded Rio de Janeiro State University’s microcirculation lab, where she carried out her microvascular dysfunction research!
#WomenInSTEM #MedSky #HistSci
#WomenInSTEM #MedSky #HistSci
February 14, 2025 at 12:46 PM
Tomorrow is the 75th birthday of Brazilian cardiovascular physician Eliele Bouskela! She founded Rio de Janeiro State University’s microcirculation lab, where she carried out her microvascular dysfunction research!
#WomenInSTEM #MedSky #HistSci
#WomenInSTEM #MedSky #HistSci
Congratulations to Nivethithia and Leah on receiving the Aletta Jacobs Award from the German Society of Microcirculation! We're incredibly proud of these two outstanding PhD students in our lab😀
April 5, 2025 at 9:31 AM
Congratulations to Nivethithia and Leah on receiving the Aletta Jacobs Award from the German Society of Microcirculation! We're incredibly proud of these two outstanding PhD students in our lab😀
New review with @resiapretorius.bsky.social Kell, D. B., Zhao, H. and Pretorius, E. (2026) Fibrinaloid Microclots-Induced Microcirculation Dysfunction: Mechanism and Laser-Based Haemodynamic Validation. Cardiovasc Sci. 3, 10005. doi.org/10.70322/cvs... #TeamClots @livuni-ismib.bsky.social
Fibrinaloid Microclots-Induced Microcirculation
Dysfunction: Mechanism and Laser-Based Haemodynamic Validation
The microcirculation typically refers to those
capillaries less than 100 μm in diameter. We have shown
that blood can clot into an anomalous amyloid form, manifesting as microclots
of typically 2–200 ...
doi.org
May 14, 2026 at 7:33 AM
New review with @resiapretorius.bsky.social Kell, D. B., Zhao, H. and Pretorius, E. (2026) Fibrinaloid Microclots-Induced Microcirculation Dysfunction: Mechanism and Laser-Based Haemodynamic Validation. Cardiovasc Sci. 3, 10005. doi.org/10.70322/cvs... #TeamClots @livuni-ismib.bsky.social
#BioHacker
#VascularAudit
#MicroCirculation
#EndothelialHealth
#TexasLeeches
#VascularAudit
#MicroCirculation
#EndothelialHealth
#TexasLeeches
September 21, 2026 at 9:20 AM
#BioHacker
#VascularAudit
#MicroCirculation
#EndothelialHealth
#TexasLeeches
#VascularAudit
#MicroCirculation
#EndothelialHealth
#TexasLeeches
A new review with
@resiapretorius.bsky.social on two more imaging methods for measuring effects of #fibrinaloid #microclots on the #microcirculation and endothelial damage. #TeamClots #pwLC #pwME preprints.org/manuscript/2.... Much pricier than #nailfold #capillaroscopy but impactful.
@resiapretorius.bsky.social on two more imaging methods for measuring effects of #fibrinaloid #microclots on the #microcirculation and endothelial damage. #TeamClots #pwLC #pwME preprints.org/manuscript/2.... Much pricier than #nailfold #capillaroscopy but impactful.
preprints.org
June 26, 2025 at 11:35 PM
A new review with
@resiapretorius.bsky.social on two more imaging methods for measuring effects of #fibrinaloid #microclots on the #microcirculation and endothelial damage. #TeamClots #pwLC #pwME preprints.org/manuscript/2.... Much pricier than #nailfold #capillaroscopy but impactful.
@resiapretorius.bsky.social on two more imaging methods for measuring effects of #fibrinaloid #microclots on the #microcirculation and endothelial damage. #TeamClots #pwLC #pwME preprints.org/manuscript/2.... Much pricier than #nailfold #capillaroscopy but impactful.
Wishing a happy 76th birthday to Brazilian physician Eliete Bouskela, whose research unveiled new ways of studying microcirculation to get at the bottom of what is happening when those systems go awry. We hope you have a good one, Dr. Bouskela!
#WomenInSTEM #MedSky #BioSky 🧪⚕️
#WomenInSTEM #MedSky #BioSky 🧪⚕️
February 15, 2026 at 5:24 PM
Wishing a happy 76th birthday to Brazilian physician Eliete Bouskela, whose research unveiled new ways of studying microcirculation to get at the bottom of what is happening when those systems go awry. We hope you have a good one, Dr. Bouskela!
#WomenInSTEM #MedSky #BioSky 🧪⚕️
#WomenInSTEM #MedSky #BioSky 🧪⚕️
A study of 35,000+ women linked higher blueberry intake to a reduced risk of age-related macular degeneration. 👁️🫐
Anthocyanins protect retinal cells from oxidative stress and support eye microcirculation.
Full science breakdown in reply 👇🧵
Anthocyanins protect retinal cells from oxidative stress and support eye microcirculation.
Full science breakdown in reply 👇🧵
September 20, 2026 at 10:01 PM
A study of 35,000+ women linked higher blueberry intake to a reduced risk of age-related macular degeneration. 👁️🫐
Anthocyanins protect retinal cells from oxidative stress and support eye microcirculation.
Full science breakdown in reply 👇🧵
Anthocyanins protect retinal cells from oxidative stress and support eye microcirculation.
Full science breakdown in reply 👇🧵
5) The authors also note a reduction of bone marrow proteins, proteins pointing to neutrophil maturation, and proteins associated with microcirculation and hypoxia responses (VIM, ANTXR2, CXADR).
June 1, 2025 at 6:34 PM
5) The authors also note a reduction of bone marrow proteins, proteins pointing to neutrophil maturation, and proteins associated with microcirculation and hypoxia responses (VIM, ANTXR2, CXADR).
Mottling precedes MAP drops. Don't blindly increase pressors; it can worsen microcirculation. Assess fluids, lactate, and source control. Treat perfusion, not just pressure. https://bexyhub.in
Mottling precedes MAP drops. Don't blindly increase pressors; it can worsen microcirculation. Assess fluids, lactate, and source control. Treat perfusion, not just pressure. https://bexyhub.in
Mottling precedes MAP drops. Don't blindly increase pressors; it can worsen microcirculation. Assess fluids, lactate, and source control. Treat perfusion, not just pressure. https://bexyhub.in
bexyhub.in
September 24, 2026 at 2:57 AM
Mottling precedes MAP drops. Don't blindly increase pressors; it can worsen microcirculation. Assess fluids, lactate, and source control. Treat perfusion, not just pressure. https://bexyhub.in
🧠 Daily Feed of Brain Damage 🧠
With thanks to @harryspoelstra.bsky.social
link.springer.com/article/10.1...
With thanks to @harryspoelstra.bsky.social
link.springer.com/article/10.1...
Ocular microvascular changes in COVID-19: role of hypoxia, D-dimer, IL-6 and systemic treatment - Pharmacological Reports
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with endothelial dysfunction, which may also compromise the microcirculation within ocular tissues. This...
link.springer.com
May 27, 2025 at 9:12 PM
🧠 Daily Feed of Brain Damage 🧠
With thanks to @harryspoelstra.bsky.social
link.springer.com/article/10.1...
With thanks to @harryspoelstra.bsky.social
link.springer.com/article/10.1...
The expanding role of ultrasound in acute kidney injury: from B-mode to microcirculation
CCR Journal Watch
criticalcarereviews.com/latest-evide...
CCR Journal Watch
criticalcarereviews.com/latest-evide...
July 13, 2026 at 11:34 PM
The expanding role of ultrasound in acute kidney injury: from B-mode to microcirculation
CCR Journal Watch
criticalcarereviews.com/latest-evide...
CCR Journal Watch
criticalcarereviews.com/latest-evide...
"impaired microcirculation and increased arterial stiffness..." in CHILDREN.
COVID is not Mild™️. It was designated an RG-3 pathogen for a reason.
Keeping receipts so these kids can sue our a**es off when they are adults. Before they die far too young.
COVID is not Mild™️. It was designated an RG-3 pathogen for a reason.
Keeping receipts so these kids can sue our a**es off when they are adults. Before they die far too young.
March 19, 2026 at 4:12 AM
"impaired microcirculation and increased arterial stiffness..." in CHILDREN.
COVID is not Mild™️. It was designated an RG-3 pathogen for a reason.
Keeping receipts so these kids can sue our a**es off when they are adults. Before they die far too young.
COVID is not Mild™️. It was designated an RG-3 pathogen for a reason.
Keeping receipts so these kids can sue our a**es off when they are adults. Before they die far too young.
A SECOND review with @resiapretorius.bsky.social also published today Kell, D. B. and Pretorius, E. (2026) Assessing the Health and Functionality of the Microcirculation Using Thermal Imaging. J Biophotonics. 19, e70270. doi.org/10.1002/jbio... #TeamClots @livuni-ismib.bsky.social
Assessing the Health and Functionality of the Microcirculation Using Thermal Imaging
We review the techniques of thermal imaging for assessing the functional consequences of lowered blood flow in the microcirculation that accompanies many chronic, inflammatory diseases. A comparison ...
doi.org
May 14, 2026 at 9:13 AM
A SECOND review with @resiapretorius.bsky.social also published today Kell, D. B. and Pretorius, E. (2026) Assessing the Health and Functionality of the Microcirculation Using Thermal Imaging. J Biophotonics. 19, e70270. doi.org/10.1002/jbio... #TeamClots @livuni-ismib.bsky.social
Mottling in shock indicates true tissue hypoperfusion, not just benign vasoconstriction. Blind MAP chasing with vasopressors can paradoxically worsen microcirculation. Assess mottling, not just MAP. Optimize for global perfusion. https://bexyhub.in
Mottling in shock indicates true tissue hypoperfusion, not just benign vasoconstriction. Blind MAP chasing with vasopressors can paradoxically worsen microcirculation. Assess mottling, not just MAP. Optimize for global perfusion. https://bexyhub.in
Mottling in shock indicates true tissue hypoperfusion, not just benign vasoconstriction. Blind MAP chasing with vasopressors can paradoxically worsen microcirculation. Assess mottling, not just MAP. Optimize for global perfusion. https://bexyhub.in
bexyhub.in
September 24, 2026 at 3:08 AM
Mottling in shock indicates true tissue hypoperfusion, not just benign vasoconstriction. Blind MAP chasing with vasopressors can paradoxically worsen microcirculation. Assess mottling, not just MAP. Optimize for global perfusion. https://bexyhub.in