#Minipuberty
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faerynnistired.itch.io
which sounds all well and fine, right… RIGHT?! and then goes onto say “Of note, minipuberty predicts adult reproductive capacity…” and i just want to fucking scream
March 26, 2026 at 5:54 PM
nejm.org
A new review discusses minipuberty, a transient phase in infancy during which levels of gonadal hormones are similar to those in adults, after which they become undetectable until the onset of puberty. Read the full review: nej.md/3PZhsap

#MedSky #PedSky #EndoSky
Review Article Clinical Implications of Minipuberty Anders Juul, M.D., D.M.Sc., Ph.D. An illustrated diagram of the hypothalamic–pituitary–gonadal (HPG) hormone axis in male infants, children, and adolescents.
March 25, 2026 at 10:00 PM
cambrianera.radical.town
no distinction between endogenous puberty and not is made, instead it's dismissed on the grounds of 'minipuberty' and that boys exercise more.
January 11, 2026 at 9:16 PM
not-eye.bsky.social
I got you on the provided example btw.

They identify an approximately 5% difference in prepubescent kids. Their “several” (actually 2) reasonings are…

1. Some boys get early “minipuberty”…

2. Boys tend to be socialized into more physical activities than girls…
A screenshot from the letter to the editor that was provided by the weirdo we’re talking to. It reads as follows: “There are several bioplausible explanations for the male-female performance gaps seen before puberty in these sports. First, transient increases in sex hormones during early life (so-called "minipuberty") are associated with increased growth velocity (14) and reduced adipose accumulation (15) among male infants compared with female infants, and greater muscle mass (16) and muscle strength (17) among boys compared with girls. Second, boys tend to run and jump more than girls during unstructured play and spend more time engaged in higher-intensity physical activity (18, 19). Such activities could produce an informal training effect in boys. The extent to which these sex differences in children reflect the impact of biology, socialization, or both is a matter of discussion (20), but differences in early childhood body composition indicate that at least some of the male-female performance gap among prepubertal children is due to intrinsic biological factors.” I edited a black box toward the bottom pointing to the part that starts with “but differences in early childhood” near the bottom. Inside the box are red words that read “source? Reference? Hello?” Bellow that are two graphs. One labeled “track and field” and the other labeled “freestyle swimming”
September 21, 2026 at 2:48 AM
nejm.org
A new review by Anders Juul, MD, DMSc, PhD, summarizes the current understanding of minipuberty and describes its potential clinical implications. Read the full review: nej.md/3PZhsap

#MedSky #PedSky #EndoSky
The key points from the Review Article "Clinical Implications of Minipuberty"
April 1, 2026 at 1:01 PM
cp-cellmetabolism.bsky.social
Online now: Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice
Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice
Polycystic ovary syndrome (PCOS) is the most common female reproductive and metabolic disorder. PCOS treatment is limited to symptom management. Here, Cotellessa et al. showed that high levels of anti-Müllerian hormone (AMH) during minipuberty may contribute to PCOS development and discovered that blocking AMH’s effects in mice prevented PCOS-like symptoms.
dlvr.it
April 11, 2025 at 3:42 PM
rridrobot.bsky.social
Beckman Coulter's resource, RRID:AB_2827405, was just reported to be used in "Ovarian and Uterine Morphology in Minipuberty: Associations with Reproductive Hormones. A COPANA Study of 302 girls". Thank you for making your methods matter! #methodsmatter #ReproducibleResearch
doi.org
March 7, 2025 at 8:01 AM
rridrobot.bsky.social
A paper using RRID:AB_141607 from @thermofishersci.bsky.social was just published in Cell Metabolism. Thanks for making your methods matter! #reproducibility #ReproducibleResearch #methodsmatter
Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice
doi.org
April 17, 2025 at 7:00 AM
rridrobot.bsky.social
RRID:AB_2934107 was used by the authors of the The Journal of Clinical Endocrinology & Metabolism paper "Serum DLK1 During Minipuberty and Pubertal Transition in Healthy Girls and in Girls with Precocious Puberty". Thank you for making your methods matter! #reproducibility #RRID
doi.org
March 12, 2025 at 7:01 AM
shihcheng.bsky.social
Minipuberty is a key phase in infants (1-3 months) marked by a surge in HPG activity; in boys, FSH, LH, testosterone and inhibin B peak. PMID:41880614, N Engl J Med 2026, @NEJM https://doi.org/10.1056/NEJMra2305989 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://doi.org/10.1056/NEJMra2305989
No description available
doi.org
May 14, 2026 at 1:10 AM
madeindenmark.bsky.social
Cohort profile: The Copenhagen Analgesic Study-The COPANA cohort.
pubmed.ncbi.nlm.nih.gov/38453250/
#Analgesics #CohortStudy #EndocrineDisruption #GonadalFunction #HypothalamicPituitaryGonadalAxis #Minipuberty #Research #Denmark #Rigshospitalet #FetalLife #ReproductiveHealth
Cohort profile: The Copenhagen Analgesic Study-The COPANA cohort - PubMed
The Copenhagen Analgesic Study holds the potential to provide novel and comprehensive insights into the impact of early and late prenatal exposure to mild analgesics and other endocrine-disrupting chemicals on future reproductive function in the offspring.
pubmed.ncbi.nlm.nih.gov
September 9, 2026 at 4:11 PM
f16col.bsky.social
www.nejm.org/doi/full/10....
Clinical Implications of Minipuberty | NEJM
Minipuberty refers to a specific period in early postnatal life with high activity of the hypothalamic–pituitary–gonadal (HPG) hormone axis. In infant boys 1 to 3 months of age, high concentrations...
www.nejm.org
March 26, 2026 at 12:29 PM
beyondpesticides.org
Researchers in Denmark & Iceland investigate the impacts of #pesticides on sex hormones, finding that prenatal exposure to #chlorpyrifos and #2,4-D may affect the reproductive hormones in girls during minipuberty, which may have long-term implications. ow.ly/BbF950XANXv
Research Finds Maternal Pesticide Exposure Impacts Reproductive Hormones in Infant Girls - Beyond Pesticides Daily News Blog
Maternal urinary concentrations of pesticides and their metabolites reveal impacts on hormones in infant girls.
ow.ly
December 2, 2025 at 5:06 PM
nemunemu-nyanko.bsky.social
タイトル: ミニパブテルの中断が雌マウスの性行動発現に与える影響
要点1: ミニパブテルの一時的な中断が性行動の一部要素にわずかな変化を及ぼし、エストラス周期に軽微な障害を引き起こす
要点2: ミニパブテル期間は雌性の性行動には直接的な影響を与えないが、将来の不安症状の発現に関与している可能性がある
Effects of minipuberty disruption on the expression of sexual behavior in female mice.
【Sci Rep】<AbstractText>Sex steroids influence early organization of neural structures involved in expression of sexual behavior...
pubmed.ncbi.nlm.nih.gov
December 29, 2024 at 3:49 PM
rridrobot.bsky.social
RRIDs were included in this in The Journal of Clinical Endocrinology & Metabolism paper. We value the author's support of reproducibility. #methodsmatter #BetterScience #OpenResearch
Reproductive hormones during minipuberty suggest subtle testicular impairments in boys with hypospadias
Read the full paper: Reproductive hormones during minipuberty suggest subtle testicular impairments in boys with hypospadias
doi.org
June 28, 2026 at 7:00 AM
rridrobot.bsky.social
RRIDs were included in this in The Journal of Clinical Endocrinology & Metabolism paper. Thanks for making your methods matter! #RRID #OpenResearch #OpenScience
Changes in circulating levels of miR-30b during minipuberty and puberty in girls
Read the full paper: Changes in circulating levels of miR-30b during minipuberty and puberty in girls
doi.org
June 28, 2026 at 7:00 AM
scientificchina.bsky.social
Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice: Cell Metabolism www.cell.com/cell-metabol...
Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice
Polycystic ovary syndrome (PCOS) is the most common female reproductive and metabolic disorder. PCOS treatment is limited to symptom management. Here, Cotellessa et al. showed that high levels of anti...
www.cell.com
April 13, 2025 at 5:06 AM
bigearthdata.ai
Minipuberty Hormone Signals Hint at Future Fertility in Turner Syndrome
->European Medical Journal | More from Lil Dr Glen EcoChat at BigEarthData.ai
Minipuberty Hormone Signals Hint at Future Fertility in Turner Syndrome
In a prospective multicentre cohort of 23 infant girls with Turner syndrome, investigators have shown that hormone patterns during “minipuberty” may offer an early window into ovarian reserve and future reproductive potential. Blood sampling at 3 and 9 months revealed...
www.emjreviews.com
January 5, 2026 at 5:25 AM
pandeylab.bsky.social
Our new book chapter, "Testicular Steroidogenesis," maps the entire journey, from fetal differentiation and "minipuberty" to complex biosynthesis pathways and the genetic basis of DSDs.
January 25, 2026 at 9:14 PM
pandeylab.bsky.social
👶💥 "Minipuberty": The often-overlooked postnatal hormone surge crucial for male (46, X,Y) reproductive tract maturation. New publication by @pandeylab.bsky.social @dbmr-unibe.bsky.social from @unibe.ch

👉 doi.org/10.1007/978-... #Minipuberty #Hormones
January 25, 2026 at 9:14 PM
biorxiv-devbio.bsky.social
Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty. https://www.biorxiv.org/content/10.1101/2024.09.09.610834v1
Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty. https://www.biorxiv.org/content/10.1101/2024.09.09.610834v1
Gonadotrophs are the pituitary endocrine cells regulating reproductive function. They produce both l
www.biorxiv.org
September 10, 2024 at 5:32 AM
biorxiv-physio.bsky.social
Minipuberty regulates reproductive lifespan and ovarian follicular loss in a mouse model with reduced minipubertal gonadotropin levels https://www.biorxiv.org/content/10.1101/2024.08.20.608775v1
Minipuberty regulates reproductive lifespan and ovarian follicular loss in a mouse model with reduced minipubertal gonadotropin levels https://www.biorxiv.org/content/10.1101/2024.08.20.608775v1
Study question: What is the role of the physiological hypergonadotropic activity encountered at mini
www.biorxiv.org
August 21, 2024 at 5:01 PM
biorxivpreprint.bsky.social
Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty. https://www.biorxiv.org/content/10.1101/2024.09.09.610834v1
Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty. https://www.biorxiv.org/content/10.1101/2024.09.09.610834v1
Gonadotrophs are the pituitary endocrine cells regulating reproductive function. They produce both l
www.biorxiv.org
September 10, 2024 at 5:32 AM
biorxivpreprint.bsky.social
Minipuberty regulates reproductive lifespan and ovarian follicular loss in a mouse model with reduced minipubertal gonadotropin levels https://www.biorxiv.org/content/10.1101/2024.08.20.608775v1
Minipuberty regulates reproductive lifespan and ovarian follicular loss in a mouse model with reduced minipubertal gonadotropin levels https://www.biorxiv.org/content/10.1101/2024.08.20.608775v1
Study question: What is the role of the physiological hypergonadotropic activity encountered at mini
www.biorxiv.org
August 21, 2024 at 5:01 PM