Neuropixels and Optogenetics are delighted to announce the birth of
Neuropixels Opto
Combining high-resolution electrophysiology and optogenetics
Today in bioRxiv
960 sites, 28 emitters, 2 colors
By Lakunina, @karolinazsocha.bsky.social, Ladd, et al
www.biorxiv.org/content/10.1...
(1/2)
Neuropixels Opto
Combining high-resolution electrophysiology and optogenetics
Today in bioRxiv
960 sites, 28 emitters, 2 colors
By Lakunina, @karolinazsocha.bsky.social, Ladd, et al
www.biorxiv.org/content/10.1...
(1/2)
February 7, 2025 at 9:16 AM
Neuropixels and Optogenetics are delighted to announce the birth of
Neuropixels Opto
Combining high-resolution electrophysiology and optogenetics
Today in bioRxiv
960 sites, 28 emitters, 2 colors
By Lakunina, @karolinazsocha.bsky.social, Ladd, et al
www.biorxiv.org/content/10.1...
(1/2)
Neuropixels Opto
Combining high-resolution electrophysiology and optogenetics
Today in bioRxiv
960 sites, 28 emitters, 2 colors
By Lakunina, @karolinazsocha.bsky.social, Ladd, et al
www.biorxiv.org/content/10.1...
(1/2)
Neuropixels + Optogenetics = Neuropixels Opto
Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors.
Today in @natmethods.nature.com
doi.org/10.1038/s415...
Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.
Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors.
Today in @natmethods.nature.com
doi.org/10.1038/s415...
Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.
June 1, 2026 at 11:20 AM
Neuropixels + Optogenetics = Neuropixels Opto
Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors.
Today in @natmethods.nature.com
doi.org/10.1038/s415...
Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.
Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors.
Today in @natmethods.nature.com
doi.org/10.1038/s415...
Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.
Neuropixels can bend, right?
In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.
rm -rf ~/
rm -rf ~/
"The chancellor approved it"
October 12, 2025 at 5:12 PM
Neuropixels can bend, right?
All talks of the 2025 UCL #Neuropixels course are now available: www.youtube.com/playlist?lis...
For more information on the course see the website: www.ucl.ac.uk/neuropixels/...
And for those at #SfN, come say hi at the #Neuropixels booth (Number 3731) or at my Poster 👋.
Happy Neuropixeling!
For more information on the course see the website: www.ucl.ac.uk/neuropixels/...
And for those at #SfN, come say hi at the #Neuropixels booth (Number 3731) or at my Poster 👋.
Happy Neuropixeling!
2025 UCL Neuropixels Course - YouTube
Lectures at the 2025 UCL Neuropixels course (https://www.ucl.ac.uk/neuropixels/training/2025-neuropixels-course)
www.youtube.com
November 10, 2025 at 1:48 PM
All talks of the 2025 UCL #Neuropixels course are now available: www.youtube.com/playlist?lis...
For more information on the course see the website: www.ucl.ac.uk/neuropixels/...
And for those at #SfN, come say hi at the #Neuropixels booth (Number 3731) or at my Poster 👋.
Happy Neuropixeling!
For more information on the course see the website: www.ucl.ac.uk/neuropixels/...
And for those at #SfN, come say hi at the #Neuropixels booth (Number 3731) or at my Poster 👋.
Happy Neuropixeling!
Excited to share that I’ve recently been named a Kavli-Grossman Scholar at Columbia University. This funding will support our efforts to combine peripheral somatosensory manipulations with large scale brain recordings using Neuropixels.
March 17, 2025 at 5:56 PM
Excited to share that I’ve recently been named a Kavli-Grossman Scholar at Columbia University. This funding will support our efforts to combine peripheral somatosensory manipulations with large scale brain recordings using Neuropixels.
Neuropixels Ultra!
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings
To understand the neural basis of behavior, it is essential to sensitively and accurately measure neural activity at single-neuron and single-spike re…
www.sciencedirect.com
September 30, 2025 at 3:11 PM
Neuropixels Ultra!
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
(1/6) Thrilled to share our triple-N dataset (Non-human Primate Neural Responses to Natural Scenes)! It captures thousands of high-level visual neuron responses in macaques to natural scenes using #Neuropixels.
May 11, 2025 at 1:33 PM
(1/6) Thrilled to share our triple-N dataset (Non-human Primate Neural Responses to Natural Scenes)! It captures thousands of high-level visual neuron responses in macaques to natural scenes using #Neuropixels.
Is spatial navigation innate 🧠? Using #NeuroPixels we show that the #torus 🍩 underlying the #GridCell map exists already on day 10 in rats — before pups open eyes and ears and before they start upright walking. 🧵1:4
👇
www.biorxiv.org/content/10.6...
👇
www.biorxiv.org/content/10.6...
www.biorxiv.org
March 11, 2026 at 10:35 AM
Is spatial navigation innate 🧠? Using #NeuroPixels we show that the #torus 🍩 underlying the #GridCell map exists already on day 10 in rats — before pups open eyes and ears and before they start upright walking. 🧵1:4
👇
www.biorxiv.org/content/10.6...
👇
www.biorxiv.org/content/10.6...
Thrilled to share our latest work exploring new avenues for combining #Neuropixels with #Optogenetics! Congratulations to co-first author Anna Lakunina, the Neuropixels Opto Consortium and collaborators! www.biorxiv.org/content/10.1...
February 12, 2025 at 9:34 AM
Thrilled to share our latest work exploring new avenues for combining #Neuropixels with #Optogenetics! Congratulations to co-first author Anna Lakunina, the Neuropixels Opto Consortium and collaborators! www.biorxiv.org/content/10.1...
(From
@EnnyvBeest@mastodon.social)
The talks from the UCL Neuropixels course 2024 are now on YouTube!
We had amazing speakers covering usage, new tools, and discoveries.
Special thanks to @intlbrainlab.bsky.social.
youtube.com/playlist?lis...
More info: www.ucl.ac.uk/neuropixels/...
@EnnyvBeest@mastodon.social)
The talks from the UCL Neuropixels course 2024 are now on YouTube!
We had amazing speakers covering usage, new tools, and discoveries.
Special thanks to @intlbrainlab.bsky.social.
youtube.com/playlist?lis...
More info: www.ucl.ac.uk/neuropixels/...
www.youtube.com
November 24, 2024 at 2:39 PM
(From
@EnnyvBeest@mastodon.social)
The talks from the UCL Neuropixels course 2024 are now on YouTube!
We had amazing speakers covering usage, new tools, and discoveries.
Special thanks to @intlbrainlab.bsky.social.
youtube.com/playlist?lis...
More info: www.ucl.ac.uk/neuropixels/...
@EnnyvBeest@mastodon.social)
The talks from the UCL Neuropixels course 2024 are now on YouTube!
We had amazing speakers covering usage, new tools, and discoveries.
Special thanks to @intlbrainlab.bsky.social.
youtube.com/playlist?lis...
More info: www.ucl.ac.uk/neuropixels/...
Proposal recommended for funding! Which means we have a fresh, 3-year-funded position available for a computational postdoc interested in studying dynamics of social interactions in rats, with simultaneous Neuropixels data to follow 🐀🐀🐀
Proper job ad pending, but email me if interested!
Proper job ad pending, but email me if interested!
July 15, 2025 at 8:54 PM
Proposal recommended for funding! Which means we have a fresh, 3-year-funded position available for a computational postdoc interested in studying dynamics of social interactions in rats, with simultaneous Neuropixels data to follow 🐀🐀🐀
Proper job ad pending, but email me if interested!
Proper job ad pending, but email me if interested!
Calcium imaging / Patch Clamp / Neuropixels
Associate Professor / Full Professor / Assistant Professor
October 8, 2025 at 11:03 AM
Calcium imaging / Patch Clamp / Neuropixels
-Neuron subtypes: can we just ignore them?
-Did evolution make brains recurrent to annoy us?
-Neuropixels should be the name of an imaging tool
-Did evolution make brains recurrent to annoy us?
-Neuropixels should be the name of an imaging tool
Hello numerous people who joined and followed! I want to hear your neuroscience takes, but not the same old debates. There's so much we can discuss that's truly new. Here I'll start:
-The brain: too big, or not big enough
-Most overrated region of cortex
-manifolds: isn't just one fold sufficient
-The brain: too big, or not big enough
-Most overrated region of cortex
-manifolds: isn't just one fold sufficient
November 20, 2024 at 3:28 AM
-Neuron subtypes: can we just ignore them?
-Did evolution make brains recurrent to annoy us?
-Neuropixels should be the name of an imaging tool
-Did evolution make brains recurrent to annoy us?
-Neuropixels should be the name of an imaging tool
@guidomeijer.com has #neuropixels preprocessing worked out for you!
Do you do Neuropixel recordings and are you struggling with preprocessing? The Power Pixels pipeline is an easy-to-use pipeline from raw data to neural activity of single neurons in specified brain regions 🧠 Now on bioRxiv!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Power Pixels: a turnkey pipeline for processing of Neuropixel recordings
There are many open-source tools available for the processing of neuronal data acquired using Neuropixels probes. Each of these tools, focuses on a part of the process from raw data to single neuron a...
www.biorxiv.org
July 1, 2025 at 3:30 PM
@guidomeijer.com has #neuropixels preprocessing worked out for you!
From a collaborator: "single cell [RNAseq] is neuropixels for cell biologists"
March 20, 2025 at 1:25 PM
From a collaborator: "single cell [RNAseq] is neuropixels for cell biologists"
Our paper on NHP neuropixels is finally out in Nat Neuro! These probes have already been transformative and will usher in a new era of primate neuroscience. I am extremely proud to have played a very small role in this project. I can't wait to see what our community discovers. tinyurl.com/54u3hrj8
Large-scale high-density brain-wide neural recording in nonhuman primates - Nature Neuroscience
Neuropixels 1.0 NHP is a 45-mm, high-density silicon probe capable of recording large numbers of neurons with single-neuron resolution from most areas in a macaque’s brain.
tinyurl.com
June 23, 2025 at 7:31 PM
Our paper on NHP neuropixels is finally out in Nat Neuro! These probes have already been transformative and will usher in a new era of primate neuroscience. I am extremely proud to have played a very small role in this project. I can't wait to see what our community discovers. tinyurl.com/54u3hrj8
🧠📢 New preprint alert
Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵
#neuroskyence #compneurosky
Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵
#neuroskyence #compneurosky
December 5, 2025 at 8:42 PM
🧠📢 New preprint alert
Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵
#neuroskyence #compneurosky
Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵
#neuroskyence #compneurosky
Join the 2025 UCL Neuropixels course (free and online!),
22-24th of October:
Day 1 and 2: Get started with the basics and the latest updates on hardware & software.
Day 3: Focus on how to analyse the many neurons you recorded.
More info and to register:
www.ucl.ac.uk/neuropixels/...
22-24th of October:
Day 1 and 2: Get started with the basics and the latest updates on hardware & software.
Day 3: Focus on how to analyse the many neurons you recorded.
More info and to register:
www.ucl.ac.uk/neuropixels/...
2025 Neuropixels course
A free online course on Neuropixels, 22-24 October 2025
www.ucl.ac.uk
September 16, 2025 at 4:36 PM
Join the 2025 UCL Neuropixels course (free and online!),
22-24th of October:
Day 1 and 2: Get started with the basics and the latest updates on hardware & software.
Day 3: Focus on how to analyse the many neurons you recorded.
More info and to register:
www.ucl.ac.uk/neuropixels/...
22-24th of October:
Day 1 and 2: Get started with the basics and the latest updates on hardware & software.
Day 3: Focus on how to analyse the many neurons you recorded.
More info and to register:
www.ucl.ac.uk/neuropixels/...
The massive 7T-fMRI Natural Scenes Dataset (NSD) has been extended to Neuropixels recordings in macaques! Exciting resource for inter-species comparisons by Li et al. @natneuro.nature.com. www.nature.com/articles/s41...
Also nice News & Views by Kay and colleagues! www.nature.com/articles/s41...
Also nice News & Views by Kay and colleagues! www.nature.com/articles/s41...
June 15, 2026 at 3:06 PM
The massive 7T-fMRI Natural Scenes Dataset (NSD) has been extended to Neuropixels recordings in macaques! Exciting resource for inter-species comparisons by Li et al. @natneuro.nature.com. www.nature.com/articles/s41...
Also nice News & Views by Kay and colleagues! www.nature.com/articles/s41...
Also nice News & Views by Kay and colleagues! www.nature.com/articles/s41...
i want to neuropixels these things
Your scientists were so preoccupied with whether they could, they didn't stop to think if they should
www.theguardian.com/science/2025...
www.theguardian.com/science/2025...
Scientists aiming to bring back woolly mammoth create woolly mice
Genetically modified mice have traits geared towards cold tolerance, in step towards modifying elephants
www.theguardian.com
March 6, 2025 at 6:45 PM
i want to neuropixels these things
The sound of cells in the brain just doesn’t get old! It’s how I fell in love with #neuroscience 🧠🧪👩🏻🔬
Celebrating small victories - first #neuropixels recordings in the lab. Congrats to the team that made it happen!
Celebrating small victories - first #neuropixels recordings in the lab. Congrats to the team that made it happen!
May 21, 2025 at 1:34 PM
The sound of cells in the brain just doesn’t get old! It’s how I fell in love with #neuroscience 🧠🧪👩🏻🔬
Celebrating small victories - first #neuropixels recordings in the lab. Congrats to the team that made it happen!
Celebrating small victories - first #neuropixels recordings in the lab. Congrats to the team that made it happen!
Many of the scientific questions we're interested in tackling require studying learning over long periods of time across the brain. This is challenging – which is why we're excited to say we've been developing a system for chronic wireless recording using long Neuropixels probes in macaque monkeys.
June 12, 2026 at 6:28 PM
Many of the scientific questions we're interested in tackling require studying learning over long periods of time across the brain. This is challenging – which is why we're excited to say we've been developing a system for chronic wireless recording using long Neuropixels probes in macaque monkeys.
Our study is out in Nature!
Using wireless Neuropixels we recorded hippocampal activity in freely flying bats and uncovered replay and theta(less) sweeps, revealing striking differences from classic rodent models.
👉 www.nature.com/articles/s41...
Using wireless Neuropixels we recorded hippocampal activity in freely flying bats and uncovered replay and theta(less) sweeps, revealing striking differences from classic rodent models.
👉 www.nature.com/articles/s41...
Replay and representation dynamics in the hippocampus of freely flying bats - Nature
Nature - Replay and representation dynamics in the hippocampus of freely flying bats
www.nature.com
July 9, 2025 at 3:08 PM
Our study is out in Nature!
Using wireless Neuropixels we recorded hippocampal activity in freely flying bats and uncovered replay and theta(less) sweeps, revealing striking differences from classic rodent models.
👉 www.nature.com/articles/s41...
Using wireless Neuropixels we recorded hippocampal activity in freely flying bats and uncovered replay and theta(less) sweeps, revealing striking differences from classic rodent models.
👉 www.nature.com/articles/s41...
Systems neuroscientists could use a tool that allows them to tweak neuronal activity and record at the same time. The Neuropixels Opto probe, although still a protoype, might be such a device.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuropixels/...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuropixels/...
‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures
The tool provides a new way to characterize cells and study neuronal circuits.
www.thetransmitter.org
April 29, 2025 at 2:10 PM
Systems neuroscientists could use a tool that allows them to tweak neuronal activity and record at the same time. The Neuropixels Opto probe, although still a protoype, might be such a device.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuropixels/...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuropixels/...