Eighty-four days, 210 pills and I-don't-wanna-talk-about-it dollars later, this little dude is finished with his neuropathic FIP wonderdrug treatment. Science is rad.
May 18, 2025 at 6:55 PM
Eighty-four days, 210 pills and I-don't-wanna-talk-about-it dollars later, this little dude is finished with his neuropathic FIP wonderdrug treatment. Science is rad.
Brand-new, merino wool socks for neuropathic feet are a genuine treat.
Blessings.
Blessings.
September 24, 2026 at 11:35 PM
Brand-new, merino wool socks for neuropathic feet are a genuine treat.
Blessings.
Blessings.
neuropathic itches are actual hell :-)
September 30, 2024 at 10:55 PM
neuropathic itches are actual hell :-)
The swelling and stiffness in my knees has slowly been going down along with the neuropathic pain
September 23, 2026 at 3:28 AM
The swelling and stiffness in my knees has slowly been going down along with the neuropathic pain
I’ll change from venlafaxine to duloxetine, which helps against neuropathic pain. let’s see how it goes, less pain would be great
June 27, 2025 at 7:47 AM
I’ll change from venlafaxine to duloxetine, which helps against neuropathic pain. let’s see how it goes, less pain would be great
Updated guidelines for the treatment of Neuropathic Pain just published in Lancet Neurology. It was quite the experience, and honor, to be involved in this project along with so many NeuPSIG colleagues. #PainResearch
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Pharmacotherapy and non-invasive neuromodulation for neuropathic pain: a systematic review and meta-analysis
There remains a substantial unmet need for effective and safe treatments for neuropathic pain. The Neuropathic Pain Special Interest Group aimed to up…
www.sciencedirect.com
April 17, 2025 at 10:58 PM
Updated guidelines for the treatment of Neuropathic Pain just published in Lancet Neurology. It was quite the experience, and honor, to be involved in this project along with so many NeuPSIG colleagues. #PainResearch
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Personal update: Last week’s operation led to some nerve damage & rising pain. Neuropathic, apparently. I’m still in hospital. But I have a Fentanyl button. Today is my birthday. Seems apt to spend it taking some hardcore drugs & wearing something backless
November 22, 2024 at 6:17 AM
Personal update: Last week’s operation led to some nerve damage & rising pain. Neuropathic, apparently. I’m still in hospital. But I have a Fentanyl button. Today is my birthday. Seems apt to spend it taking some hardcore drugs & wearing something backless
As a woman just beginning my journey with neuropathic pain, I am so glad I live in Australia.
December 11, 2024 at 9:43 AM
As a woman just beginning my journey with neuropathic pain, I am so glad I live in Australia.
Protip: don't take your neuropathic pain medication in the middle of the day
February 20, 2025 at 9:44 PM
Protip: don't take your neuropathic pain medication in the middle of the day
Currently? Gabapentin. Neuropathic pain is no joke.
January 24, 2026 at 7:25 AM
Currently? Gabapentin. Neuropathic pain is no joke.
@denklab.bsky.social leads an international consortium awarded €1.4m by @eraneuron.bsky.social to research causes and treatments for #NeuropathicPain.
@mwklab.bsky.social @carolineospelt.bsky.social are also chief investigators.
@nihrmaudsleybrc.bsky.social
www.kcl.ac.uk/news/interna...
@mwklab.bsky.social @carolineospelt.bsky.social are also chief investigators.
@nihrmaudsleybrc.bsky.social
www.kcl.ac.uk/news/interna...
International Neuropathic Pain consortium awarded €1.4m grant | King's College London
DECIPHER, an international consortium on Neuropathic Pain led by King’s College London, has been awarded €1.4m by ERA-NET Neuron to research the role of connective tissue in neuropathic pain.
www.kcl.ac.uk
March 24, 2026 at 9:45 AM
@denklab.bsky.social leads an international consortium awarded €1.4m by @eraneuron.bsky.social to research causes and treatments for #NeuropathicPain.
@mwklab.bsky.social @carolineospelt.bsky.social are also chief investigators.
@nihrmaudsleybrc.bsky.social
www.kcl.ac.uk/news/interna...
@mwklab.bsky.social @carolineospelt.bsky.social are also chief investigators.
@nihrmaudsleybrc.bsky.social
www.kcl.ac.uk/news/interna...
Gabapentin works better on some types of pain than others. Neuropathic pain responds well, visceral pain does not. It's an adjunct treatment, rarely a stand alone.
August 6, 2026 at 10:15 PM
Gabapentin works better on some types of pain than others. Neuropathic pain responds well, visceral pain does not. It's an adjunct treatment, rarely a stand alone.
"We believe that internal tremors [in #LongCovid] represent... dysautonomia & small fiber neuropathy... caused by hypovolemia, cerebral hypoperfusion, hyperadrenergic state, mast cell hyperactivation, & neuropathic processes affecting small nerve fibers."
www.mdpi.com/2035-8377/17...
www.mdpi.com/2035-8377/17...
www.mdpi.com
January 8, 2026 at 10:04 PM
"We believe that internal tremors [in #LongCovid] represent... dysautonomia & small fiber neuropathy... caused by hypovolemia, cerebral hypoperfusion, hyperadrenergic state, mast cell hyperactivation, & neuropathic processes affecting small nerve fibers."
www.mdpi.com/2035-8377/17...
www.mdpi.com/2035-8377/17...
Are you interested in neuropathic #PainResearch #painscience? 🧪🧠? Get your abstract in now to join us for #NeuPSIG2025 in Berlin! neupsigcongress.org
NeuPSIG 2025 – International Congress on Neuropathic Pain
neupsigcongress.org
January 23, 2025 at 6:19 PM
Are you interested in neuropathic #PainResearch #painscience? 🧪🧠? Get your abstract in now to join us for #NeuPSIG2025 in Berlin! neupsigcongress.org
"Pregabalin (brand name Lyrica) is an anticonvulsant and neuropathic pain medication used to treat seizures, fibromyalgia, and nerve pain (diabetic, postherpetic, or spinal). It works by reducing the number of pain signals sent by damaged nerves." oohhh... Oh well, that's scary as hell.
April 15, 2026 at 9:41 PM
"Pregabalin (brand name Lyrica) is an anticonvulsant and neuropathic pain medication used to treat seizures, fibromyalgia, and nerve pain (diabetic, postherpetic, or spinal). It works by reducing the number of pain signals sent by damaged nerves." oohhh... Oh well, that's scary as hell.
Nice summary of auto-antibodies in neuropathic pain #PainResearch www.cell.com/trends/molec...
Autoantibodies as drivers of neuropathic pain
Emerging evidence, supported by clinical responses to immunotherapy and the recapitulation
of sensory symptoms in passive transfer models, shows that autoantibodies (AAbs) may
drive neuropathic pain. ...
www.cell.com
August 4, 2025 at 8:46 AM
Nice summary of auto-antibodies in neuropathic pain #PainResearch www.cell.com/trends/molec...
Covid Might Have Changed People’s Personalities, Study Suggests.
We Mean The Restrictions In Place To Stop Its Spread Of Course, Not The Neurotropic, Neuropathic Virus That Causes Brain Inflammation And Damage And Memory Loss.
We Mean The Restrictions In Place To Stop Its Spread Of Course, Not The Neurotropic, Neuropathic Virus That Causes Brain Inflammation And Damage And Memory Loss.
September 22, 2023 at 1:09 PM
Covid Might Have Changed People’s Personalities, Study Suggests.
We Mean The Restrictions In Place To Stop Its Spread Of Course, Not The Neurotropic, Neuropathic Virus That Causes Brain Inflammation And Damage And Memory Loss.
We Mean The Restrictions In Place To Stop Its Spread Of Course, Not The Neurotropic, Neuropathic Virus That Causes Brain Inflammation And Damage And Memory Loss.
New #ScienceSignaling research in mice delineates how the hormone CRH triggers neuropathic pain in peripheral sensory nerves and suggests that targeted inhibition of this hormone could lead to long-lasting pain relief while minimizing side effects. https://scim.ag/4mWOF2H
SMAD1-mediated induction of peripheral CRH after nerve injury promotes neuropathic pain by activating spinal CRHR2
Blocking peripheral production of the stress hormone CRH suppresses neuropathic pain in mice.
scim.ag
May 1, 2026 at 6:03 PM
New #ScienceSignaling research in mice delineates how the hormone CRH triggers neuropathic pain in peripheral sensory nerves and suggests that targeted inhibition of this hormone could lead to long-lasting pain relief while minimizing side effects. https://scim.ag/4mWOF2H
I hope it’s shingles. With bad neuropathic symptoms.
March 2, 2026 at 6:21 PM
I hope it’s shingles. With bad neuropathic symptoms.
they just advertised a homeopathic product for neuropathic pain and I really wish everyone involved in producing the product and the ad some neuropathic pain that they can then try to treat with homeopathy
March 18, 2026 at 6:29 PM
they just advertised a homeopathic product for neuropathic pain and I really wish everyone involved in producing the product and the ad some neuropathic pain that they can then try to treat with homeopathy
Having just suffered 72 hrs of probable trigeminal neuralgia, I have a much greater appreciation for neuropathic pain’s ability to cause misery aka depression. #doctorhumbled #empathyneeded
December 22, 2024 at 3:18 AM
Having just suffered 72 hrs of probable trigeminal neuralgia, I have a much greater appreciation for neuropathic pain’s ability to cause misery aka depression. #doctorhumbled #empathyneeded
Gabapentin 100s helped a little with my nighttime neuropathic foots. Neurologist prescribed 300s made it vanish.
September 25, 2026 at 1:42 AM
Gabapentin 100s helped a little with my nighttime neuropathic foots. Neurologist prescribed 300s made it vanish.
Check ALL your medications! Blood pressure, cholesterol and epilepsy meds do it too. Lots of us are prescribed epilepsy meds for neuropathic pain.
#Speirgorm
#Speirgorm
Reminder to anyone who takes antidepressants or antipsychotics - you are at higher risk of heat exhaustion, dehydration and sunburn.
Fluoxetine, Citalopram and Sertraline are some of the most common. If you're taking these, be extra careful in this hot weather. Sun cream, shade and lots of water!
Fluoxetine, Citalopram and Sertraline are some of the most common. If you're taking these, be extra careful in this hot weather. Sun cream, shade and lots of water!
May 26, 2026 at 8:54 AM
Check ALL your medications! Blood pressure, cholesterol and epilepsy meds do it too. Lots of us are prescribed epilepsy meds for neuropathic pain.
#Speirgorm
#Speirgorm
Because people in the comments of this thread are asking: in #vetmed, gabapentin is generally a safe and efficacious drug for neuropathic chronic pain relief, seizure control, and acute pre-visit anxiety management for dogs and cats. Sources below: 🧪
Gabapentin has only ever showed evidence of therapeutic benefit in very few, limited conditions yet it is the fifth most prescribed medicine in the US.
The continued extreme focus on prescription opioids has created entirely new problems that are not only being ignored but don’t even have solutions
The continued extreme focus on prescription opioids has created entirely new problems that are not only being ignored but don’t even have solutions
A CDC analysis found #gabapentin prescribing has risen sharply in recent years.
Gabapentin became the fifth most prescribed U.S. medication in 2024.
Here’s what experts say ⬇️
Gabapentin became the fifth most prescribed U.S. medication in 2024.
Here’s what experts say ⬇️
September 30, 2025 at 10:22 PM
Because people in the comments of this thread are asking: in #vetmed, gabapentin is generally a safe and efficacious drug for neuropathic chronic pain relief, seizure control, and acute pre-visit anxiety management for dogs and cats. Sources below: 🧪
Testosterone appears to confer the vulnerability, says Robert Sorge.
A reversal of SNI-induced alodynia with a TLR4 antagonist
Again, this works in male mice but isn't in female mice
Spinal Cord TLR4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice
A reversal of SNI-induced alodynia with a TLR4 antagonist
Again, this works in male mice but isn't in female mice
Spinal Cord TLR4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice
September 23, 2026 at 7:54 PM
Testosterone appears to confer the vulnerability, says Robert Sorge.
A reversal of SNI-induced alodynia with a TLR4 antagonist
Again, this works in male mice but isn't in female mice
Spinal Cord TLR4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice
A reversal of SNI-induced alodynia with a TLR4 antagonist
Again, this works in male mice but isn't in female mice
Spinal Cord TLR4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice