Our recent Editor's Choice, from researchers at Mass General Hospital, highlight CS-1103 as a promising drug candidate for the treatment of meth overdose, for which no targeted therapies exist.
Read and share their research: https://ow.ly/ychT51033Qz
#pharmsky 🧪
Read and share their research: https://ow.ly/ychT51033Qz
#pharmsky 🧪
November 2, 2026 at 7:00 PM
Our recent Editor's Choice, from researchers at Mass General Hospital, highlight CS-1103 as a promising drug candidate for the treatment of meth overdose, for which no targeted therapies exist.
Read and share their research: https://ow.ly/ychT51033Qz
#pharmsky 🧪
Read and share their research: https://ow.ly/ychT51033Qz
#pharmsky 🧪
A study reveals shared neural geometries in the hippocampus of bilinguals, with "cross-language neurons" showing correlated responses to equivalent words in English and Spanish. PMID:42341760, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00579-9 #Medsky #Pharmsky #RNA #ASHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00579-9
No description available
www.cell.com
November 2, 2026 at 4:00 AM
A new study reveals a LLM-based framework that accelerates CAR T target discovery, identifying GPNMB as a promising target across melanoma, leukemia, and colorectal cancer. PMID:42349381, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00652-5 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00652-5
No description available
www.cell.com
November 2, 2026 at 9:00 PM
New research shows ~50% of fertilized human eggs arrest in pre-implantation due to error-prone 2nd mitotic divisions. PLK4 inhibition can reduce centriole overduplication! PMID:42276044, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00637-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00637-9
No description available
www.cell.com
November 2, 2026 at 10:00 PM
A study found that 3' UTRs of 2,700+ human mRNAs with conserved nucleotides regulate protein activity by co-translationally folding IDRs, enhancing JMJD3 function. PMID:42259285, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00576-3 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00576-3
No description available
www.cell.com
October 31, 2026 at 4:00 AM
AI-driven discovery of GPNMB CAR T cells shows promise as a multi-cancer therapy, optimizing targets through single-cell RNA sequencing analysis, enhancing therapeutic efficacy. PMID:42349383, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00651-3 #Medsky #Pharmsky #RNA #ASHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00651-3
No description available
www.cell.com
November 2, 2026 at 2:00 AM
A novel single-cell tech, D&D-seq, maps transient DNA-protein interactions, revealing how TFs shape gene expression via chromatin dynamics. Key insights await! PMID:42242226, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00573-8 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00573-8
No description available
www.cell.com
November 1, 2026 at 11:00 PM
Two clades of SARS-CoV-2-related coronaviruses co-circulating in Thai horseshoe bats show one binds human ACE2, revealing potential zoonotic risks. Exciting virological insights! PMID:42097139, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600454X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S009286742600454X
No description available
www.cell.com
October 30, 2026 at 8:00 PM
Two clades of SARS-CoV-2-related coronaviruses co-circulating in Thai horseshoe bats show one binds human ACE2, revealing potential zoonotic risks. Exciting virological insights! PMID:42097139, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600454X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
A phytoscreen of 43 fruits and veggies reveals garlic as a strong deterrent against mating and egg-laying in Drosophila, with diallyl disulfide being key! 🧄 PMID:41999745, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00338-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00338-7
No description available
www.cell.com
October 31, 2026 at 8:00 AM
Exploring SRD: Beyond dopamine! Revealing multiple pathways causing diverse symptoms. Elevate understanding! 🚀🔍 PMID:42418174, JAMA Psychiatry 2026, @JAMAPsych https://doi.org/10.1001/jamapsychiatry.2026.1684 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://doi.org/10.1001/jamapsychiatry.2026.1684
No description available
doi.org
November 3, 2026 at 3:00 AM
New research shows ~50% of human fertilized eggs arrest due to error-prone 2nd mitotic divisions. Stochastic centriole overduplication can be suppressed by PLK4 inhibition. PMID:42276044, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00637-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00637-9
No description available
www.cell.com
October 31, 2026 at 7:00 AM
A study reveals macrometastases in breast cancer utilize a 3D morphogenetic blueprint activating a unique gene program for metastatic trabecular morphogenesis, pushing cancer growth. PMID:41923644, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600276X #Medsky #Pharmsky #RNA #ASHG 🧪
https://www.cell.com/cell/fulltext/S009286742600276X
No description available
www.cell.com
October 31, 2026 at 2:00 PM
A groundbreaking study finds TMEM154/Galvanin as a receptor that helps cells sense electric fields, guiding migration toward the cathode. #CellBiology PMID:42349380, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00638-0 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00638-0
No description available
www.cell.com
November 1, 2026 at 7:00 AM
A groundbreaking study finds TMEM154/Galvanin as a receptor that helps cells sense electric fields, guiding migration toward the cathode. #CellBiology PMID:42349380, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00638-0 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Study of 469 neurons from C9ORF72 ALS, C9ORF72 FTD, and AD reveals increased somatic mutations, linking TOP1-mediated genomic damage across neurodegenerative disorders. PMID:42385702, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00700-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00700-2
No description available
www.cell.com
November 2, 2026 at 11:00 PM
The cGAS-STING pathway detects dsDNA, influencing immunity and tissue homeostasis. Key roles in antiviral defense, tumor immunity, and inflammation described. PMID:42349382, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00650-1 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00650-1
No description available
www.cell.com
November 1, 2026 at 9:00 PM
Mice exposed to heat stress show 40% greater susceptibility to metabolic dysfunction on an obesogenic diet, linked to increased KLK14 and altered hypothalamic astrocytes. PMID:42019490, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00346-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00346-6
No description available
www.cell.com
October 31, 2026 at 9:00 AM
LEAPER 3.0 harnesses engineered ADAR-recruiting RNAs for precise RNA editing, enhancing efficiency via AlphaFold 3 insights—revolutionizing gene therapy. PMID:42269608, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00514-3 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00514-3
No description available
www.cell.com
October 30, 2026 at 6:00 AM
A novel method, VIS-seq, analyzes ~3,000 LMNA & PTEN variants, revealing complex, disease-specific effects on cell morphology, protein localization, and activity. PMID:42127894, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00466-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00466-6
No description available
www.cell.com
November 1, 2026 at 4:00 AM
A new framework creates whole-cell digital twins from 4D lattice light-sheet microscopy, revealing intricate mitochondrial and organelle dynamics in live Cal27 cells! PMID:42379169, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00697-5 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00697-5
No description available
www.cell.com
October 30, 2026 at 4:00 PM
Paleoproteomic analysis of dental enamel from 20 Homo naledi individuals shows no male markers, suggesting a homogenous, possibly single-sex sample from Rising Star cave. PMID:42341758, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00644-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00644-6
No description available
www.cell.com
November 2, 2026 at 6:00 PM
Developed a CRISPR knockout mouse library with 84 gene-modified lines for studying host factors in influenza A, bridging lab insights to in vivo viral pathogenesis. PMID:42302780, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600591X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S009286742600591X
No description available
www.cell.com
October 30, 2026 at 9:00 AM
🌟Breaking: Expert consensus on imaging for cutaneous squamous cell carcinoma (CSCC)! New staging & surveillance guidelines to standardize practice across settings. #DermOncology PMID:42418212, JAMA Dermatol 2026 @Stanford https://doi.org/10.1001/jamadermatol.2026.2163 #Medsky #Pharmsky #RNA #ASHG 🧪
https://doi.org/10.1001/jamadermatol.2026.2163
No description available
doi.org
November 3, 2026 at 2:00 AM
🌟Breaking: Expert consensus on imaging for cutaneous squamous cell carcinoma (CSCC)! New staging & surveillance guidelines to standardize practice across settings. #DermOncology PMID:42418212, JAMA Dermatol 2026 @Stanford https://doi.org/10.1001/jamadermatol.2026.2163 #Medsky #Pharmsky #RNA #ASHG 🧪
Paleoproteomic analysis of dental enamel from 23 H. naledi specimens (20 individuals) reveals no male-specific markers, suggesting a single-sex sample. Fascinating find! PMID:42341758, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00644-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00644-6
No description available
www.cell.com
November 1, 2026 at 4:00 PM