also just look at the Wikipedia article for neurosteroids and prog and its metabolites tbh. this isn't particularly cutting edge stuff.
October 29, 2025 at 8:13 PM
also just look at the Wikipedia article for neurosteroids and prog and its metabolites tbh. this isn't particularly cutting edge stuff.
🚨 NEW PAPER 🚨
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Expanding our understanding of (mal)adapted stress physiology in psychiatric disorders: achieving single-cell characterisation of steroids and neuropeptides
Steroid hormones and neurosteroids (collectively neuroactive steroids), alongside neuropeptides, are key modulators of the central nervous system. The…
sciencedirect.com
June 10, 2025 at 10:40 PM
🚨 NEW PAPER 🚨
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
Thrilled to share our latest work in "The Neurobiology of Stress" where we highlight the intricate roles of neuropeptides and neurosteroids in psychiatric disorders, & how new technologies can answer old questions about these important signallers. sciencedirect.com/science/arti...
She did it! 🎉
Congratulations to Corinna on a successful PhD defense about photocatalysis and neurosteroids.
Very well deserved and best of luck on the next chapter! 🚀
#Milestone #PhDone
Congratulations to Corinna on a successful PhD defense about photocatalysis and neurosteroids.
Very well deserved and best of luck on the next chapter! 🚀
#Milestone #PhDone
December 16, 2025 at 3:58 PM
She did it! 🎉
Congratulations to Corinna on a successful PhD defense about photocatalysis and neurosteroids.
Very well deserved and best of luck on the next chapter! 🚀
#Milestone #PhDone
Congratulations to Corinna on a successful PhD defense about photocatalysis and neurosteroids.
Very well deserved and best of luck on the next chapter! 🚀
#Milestone #PhDone
I studied the anesthetic effects of pregnane neurosteroids in zebrafish.
July 16, 2025 at 1:15 AM
I studied the anesthetic effects of pregnane neurosteroids in zebrafish.
New day, new science 🧠🧪
We start #ICN2026 Thursday with a plenary by Laura Quintana giving a talk about "#Neurosteroids regulating year-round #aggression: insights from #electricfish" 🐟⚡️
#icn2026vancouver #neuroethology
We start #ICN2026 Thursday with a plenary by Laura Quintana giving a talk about "#Neurosteroids regulating year-round #aggression: insights from #electricfish" 🐟⚡️
#icn2026vancouver #neuroethology
July 30, 2026 at 4:05 PM
New day, new science 🧠🧪
We start #ICN2026 Thursday with a plenary by Laura Quintana giving a talk about "#Neurosteroids regulating year-round #aggression: insights from #electricfish" 🐟⚡️
#icn2026vancouver #neuroethology
We start #ICN2026 Thursday with a plenary by Laura Quintana giving a talk about "#Neurosteroids regulating year-round #aggression: insights from #electricfish" 🐟⚡️
#icn2026vancouver #neuroethology
Allopreganolones. My bloody phone keeps shortening it lol. Other neurosteroids are involved too
August 16, 2026 at 7:11 AM
Allopreganolones. My bloody phone keeps shortening it lol. Other neurosteroids are involved too
MedSky🧪#MolecularMedicine #postpartumdepression is associated with a decline in #progesterone-derived anxiolytic–#antidepressant #neurosteroids after delivery.
January 4, 2024 at 11:56 AM
MedSky🧪#MolecularMedicine #postpartumdepression is associated with a decline in #progesterone-derived anxiolytic–#antidepressant #neurosteroids after delivery.
honestly seems a lot safer than the oral 100mg i was on briefly too: no presystemic conversion of most of it into neurosteroids? wtf why is oral always the default for administrating everything
June 10, 2025 at 11:02 PM
honestly seems a lot safer than the oral 100mg i was on briefly too: no presystemic conversion of most of it into neurosteroids? wtf why is oral always the default for administrating everything
Did you know we have a host of Neuroendocrine Briefing publications to be freely used for teaching & public communication?
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
September 8, 2026 at 5:58 PM
Did you know we have a host of Neuroendocrine Briefing publications to be freely used for teaching & public communication?
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
neurosteroids are absolutely fascinating as a topic and underappreciated as a factor in mental health. this is definitely worth a read.
Before I started hormone therapy, I studied all the side effects and knew what to expect long before my first doctor’s appointment.
But it wasn’t until I put my reporter hat on that I realized how much more there is beneath the surface. And it’s really cool.
But it wasn’t until I put my reporter hat on that I realized how much more there is beneath the surface. And it’s really cool.
The surprising ways hormones can change your body
Hormone therapy can have profound effects on our immune systems, gut bacteria, our brains, senses and sex lives.
19thnews.org
September 3, 2026 at 2:40 PM
neurosteroids are absolutely fascinating as a topic and underappreciated as a factor in mental health. this is definitely worth a read.
Sertraline modulates hippocampal plasticity and learning via sigma 1 receptors, cellular stress and neurosteroids https://www.biorxiv.org/content/10.1101/2024.01.23.576911v1
Sertraline modulates hippocampal plasticity and learning via sigma 1 receptors, cellular stress and neurosteroids https://www.biorxiv.org/content/10.1101/2024.01.23.576911v1
In addition to modulating serotonin transport, selective serotonin reuptake inhibitors (SSRIs) have
www.biorxiv.org
January 24, 2024 at 11:16 PM
Sertraline modulates hippocampal plasticity and learning via sigma 1 receptors, cellular stress and neurosteroids https://www.biorxiv.org/content/10.1101/2024.01.23.576911v1
🦠 Researchers from IOCB (Eva Kudová) and @vschtpraha.bsky.social (Jitka Viktorová) have identified new androstane-based steroid derivatives that can significantly improve the effectiveness of existing antibiotics against resistant #Staphylococcus. 🧵
#IOCB #IOCBPrague #research #neurosteroids
#IOCB #IOCBPrague #research #neurosteroids
April 7, 2026 at 11:19 AM
🦠 Researchers from IOCB (Eva Kudová) and @vschtpraha.bsky.social (Jitka Viktorová) have identified new androstane-based steroid derivatives that can significantly improve the effectiveness of existing antibiotics against resistant #Staphylococcus. 🧵
#IOCB #IOCBPrague #research #neurosteroids
#IOCB #IOCBPrague #research #neurosteroids
Just in time for Christmas: Paper accepted 😊
Sex-specific TSPO effects on emotionality, stress axis, steroidogenesis, microbiome, and spine density in a rat model of hyperemotionality
Results from our research group FOR2858 @dfgpublic.bsky.social
www.sciencedirect.com/science/arti...
Sex-specific TSPO effects on emotionality, stress axis, steroidogenesis, microbiome, and spine density in a rat model of hyperemotionality
Results from our research group FOR2858 @dfgpublic.bsky.social
www.sciencedirect.com/science/arti...
The translocator protein 18 kDa (TSPO) ligand etifoxine in an animal model of anxiety: line- and sex-dependent effects on emotionality, stress reactivity, spine density, oxytocin receptors, steroids, ...
The treatment of stress-related disorders such as anxiety and depression is still challenging. One potential therapeutical option are neurosteroids. T…
www.sciencedirect.com
December 25, 2024 at 5:43 AM
Just in time for Christmas: Paper accepted 😊
Sex-specific TSPO effects on emotionality, stress axis, steroidogenesis, microbiome, and spine density in a rat model of hyperemotionality
Results from our research group FOR2858 @dfgpublic.bsky.social
www.sciencedirect.com/science/arti...
Sex-specific TSPO effects on emotionality, stress axis, steroidogenesis, microbiome, and spine density in a rat model of hyperemotionality
Results from our research group FOR2858 @dfgpublic.bsky.social
www.sciencedirect.com/science/arti...
As someone using 5α-Reductase inhibitors that also inhibit synthesis of these gabaergic neurosteroids I'm wondering whether I should give it a try
December 5, 2025 at 4:14 PM
As someone using 5α-Reductase inhibitors that also inhibit synthesis of these gabaergic neurosteroids I'm wondering whether I should give it a try
Multifaceted Actions of Neurosteroids https://www.biorxiv.org/content/10.1101/2025.01.22.634297v1
January 24, 2025 at 9:15 PM
Multifaceted Actions of Neurosteroids https://www.biorxiv.org/content/10.1101/2025.01.22.634297v1
it is indeed for a broad audience who is unlikely to know much of this and in particular be aware of the protective effects of specific neurosteroids for MS et...
April 26, 2025 at 2:25 PM
it is indeed for a broad audience who is unlikely to know much of this and in particular be aware of the protective effects of specific neurosteroids for MS et...
yes, oral prog is mostly all broken down in the liver and its metabolites are neurosteroids, functioning like benzos, you are getting a benzo high and not a lot of prog (i mean at this dose maybe a decent amount tbh)
January 14, 2025 at 4:00 PM
yes, oral prog is mostly all broken down in the liver and its metabolites are neurosteroids, functioning like benzos, you are getting a benzo high and not a lot of prog (i mean at this dose maybe a decent amount tbh)
afaik it has neurosteroidal effects in basically all forms except medroxyprogesterone injections. ive heard here and there that it has MORE of one if you take it orally, because the first pass metabolism that destroys it usually destroys it by converting it to said neurosteroids
June 14, 2023 at 3:51 AM
afaik it has neurosteroidal effects in basically all forms except medroxyprogesterone injections. ive heard here and there that it has MORE of one if you take it orally, because the first pass metabolism that destroys it usually destroys it by converting it to said neurosteroids
Each symposium must include 4 invited speakers (25 minutes of presentation + 5 minutes of discussion each). avoid similar symposia as in the past neurosteroids.unito.it/scientific-pro… & send emails to neurosteroids@unito.it or ask me!
https://neurosteroids.unito.it/scientific-pro…
January 29, 2025 at 4:23 AM
Each symposium must include 4 invited speakers (25 minutes of presentation + 5 minutes of discussion each). avoid similar symposia as in the past neurosteroids.unito.it/scientific-pro… & send emails to neurosteroids@unito.it or ask me!
Did you know we have a host of Neuroendocrine Briefing publications to be freely used for teaching & public communication?
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
May 26, 2026 at 9:44 AM
Did you know we have a host of Neuroendocrine Briefing publications to be freely used for teaching & public communication?
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
Part of the issue is that taking it orally causes like 97%+ of the progesterone to get metabolized into things which aren't progesterone, including two very potent neurosteroids pregnanolone and allopregnanolone. Some of these metabolites are still progestogenic, but not all of them.
May 24, 2026 at 10:23 AM
Part of the issue is that taking it orally causes like 97%+ of the progesterone to get metabolized into things which aren't progesterone, including two very potent neurosteroids pregnanolone and allopregnanolone. Some of these metabolites are still progestogenic, but not all of them.
Did you know we have a host of Neuroendocrine Briefing publications to be freely used for teaching & public communication?
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
March 19, 2026 at 2:57 PM
Did you know we have a host of Neuroendocrine Briefing publications to be freely used for teaching & public communication?
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
Two pages long, they focus on topics incl kisspeptin, neurosteroids + oxytocin.
Want to write one for us for £200? Get in touch:
www.neuroendo.org.uk...
the study data on cis women and other mammals indicates elevated progesterone typically lowers libido, but also it also partly metabolizes into neurosteroids which can make you feel good … i wouldn’t be shocked/disappointed if it doesn’t work the way some trans women experience it
July 23, 2025 at 2:16 PM
the study data on cis women and other mammals indicates elevated progesterone typically lowers libido, but also it also partly metabolizes into neurosteroids which can make you feel good … i wouldn’t be shocked/disappointed if it doesn’t work the way some trans women experience it