Thank you all the new #Bluesky followers! #BlueSky #biotech #NextGenSequencing #NextGenProteomics #SingleCell #SpatialBiology #MultiOmics #LiquidBiopsy #MCED
February 3, 2025 at 4:59 PM
Thank you all the new #Bluesky followers! #BlueSky #biotech #NextGenSequencing #NextGenProteomics #SingleCell #SpatialBiology #MultiOmics #LiquidBiopsy #MCED
February 25, 2025 at 2:37 PM
Roche SBX sequencing by expansion preprint out for everyone to read. #NGS #NextGenSequencing
sequencing.roche.com/global/en/ar...
Really cool stuff by Roche! Sequencing by Expansion Nanopore Sequencing!
www.biorxiv.org/content/10.1...
Really cool stuff by Roche! Sequencing by Expansion Nanopore Sequencing!
www.biorxiv.org/content/10.1...
Sequencing by Expansion SBX | Nanopore sequencing
Sequencing by expansion (SBX) offers a new paradigm in next-generation sequencing platform technology to expand capabilities beyond current nanopore sequencing.
sequencing.roche.com
February 25, 2025 at 3:04 PM
Roche SBX sequencing by expansion preprint out for everyone to read. #NGS #NextGenSequencing
In #NextGenSequencing news, China now outright bans the imports of Illumina $ILMN machines in US Retaliation. www.bloomberg.com/news/article...
China Bans Imports of Illumina DNA Machines in US Retaliation
China banned the import of Illumina Inc. gene-sequencing machines as part of a wave of retaliatory measures against fresh US tariffs on all Chinese goods, deepening the US company’s woes in one of its...
www.bloomberg.com
March 4, 2025 at 9:55 AM
In #NextGenSequencing news, China now outright bans the imports of Illumina $ILMN machines in US Retaliation. www.bloomberg.com/news/article...
In #NextGenSequencing news, the impact of the NIH defunding issues in the US have already been felt in the stock valuations of companies like Illumina $ILMN. The rumors today is that Illumina is also undergoing another Reduction in Force (RIF) that will affect 300 people.
February 12, 2025 at 3:19 PM
In #NextGenSequencing news, the impact of the NIH defunding issues in the US have already been felt in the stock valuations of companies like Illumina $ILMN. The rumors today is that Illumina is also undergoing another Reduction in Force (RIF) that will affect 300 people.
In #NextGenSequencing news, Illumina will release NovaSeq X 25B 100 and 200 Cycle kits, available in December 2024. Pricing of 100cyc at $11,700, and
200cyc at $14,500.
200cyc at $14,500.
December 2, 2024 at 7:55 PM
In #NextGenSequencing news, Illumina will release NovaSeq X 25B 100 and 200 Cycle kits, available in December 2024. Pricing of 100cyc at $11,700, and
200cyc at $14,500.
200cyc at $14,500.
In #NextGenSequencing news, big announcement today from Ultima Genomics with their new UG100 Solaris instrument. 50% more data, and now going from the $100 genome to the $80 genome (30x human coverage). www.prnewswire.com/news-release...
February 24, 2025 at 12:29 PM
In #NextGenSequencing news, big announcement today from Ultima Genomics with their new UG100 Solaris instrument. 50% more data, and now going from the $100 genome to the $80 genome (30x human coverage). www.prnewswire.com/news-release...
If you haven't heard of plasmidsaurus before for NextGenSequencing, have a Google at their offerings.
We are raising the quality of our bacterial genome assemblies to new heights with our hybrid ONT & Illumina bacterial sequencing option. Get the long contiguity of ONT reads, polished w/ Illumina reads to fix challenging regions such as long homopolymers. Starting at $165/sample.
January 7, 2024 at 9:07 AM
If you haven't heard of plasmidsaurus before for NextGenSequencing, have a Google at their offerings.
In #NextGenSequencing news, a new company in China, Cygnus Bio, starts offering $50 genomes with a short-read technology. This P1000X factory of 10 sequencing systems is capable of producing 80,000 human genome per year.
February 27, 2025 at 8:06 AM
In #NextGenSequencing news, a new company in China, Cygnus Bio, starts offering $50 genomes with a short-read technology. This P1000X factory of 10 sequencing systems is capable of producing 80,000 human genome per year.
In #NextGenSequencing news, Oxford Nanopore $ONTTF announced a collaboration with the UK Biobank to perform a large-scale #epigenetic profile of 50k samples targeting the causes of cancer, dementia, and complex disease. nanoporetech.com/news/oxford-...
November 28, 2024 at 2:11 PM
In #NextGenSequencing news, Oxford Nanopore $ONTTF announced a collaboration with the UK Biobank to perform a large-scale #epigenetic profile of 50k samples targeting the causes of cancer, dementia, and complex disease. nanoporetech.com/news/oxford-...
In #NextGenSequencing news, Bosch is entering the field, one more demonstration that this area which has seen incredible progress in the last 20 years is becoming more and more commoditized.
June 4, 2025 at 11:19 AM
In #NextGenSequencing news, Bosch is entering the field, one more demonstration that this area which has seen incredible progress in the last 20 years is becoming more and more commoditized.
In #NextGenSequencing news, updated the #NGS #specs w/ two upcoming Illumina $ILMN NovaSeqX 25B kits, for 100cycles and 200cycles.
Now the cheapest $/Gb short-read runs are:
(1) NovaSeq X 25B (300 cycles) = $2.22/Gb
(2) NovaSeq X 25B (200 cycles) = $2.72/Gb
(3) NovaSeq X 10B (300 cycles) = $3.54/Gb
Now the cheapest $/Gb short-read runs are:
(1) NovaSeq X 25B (300 cycles) = $2.22/Gb
(2) NovaSeq X 25B (200 cycles) = $2.72/Gb
(3) NovaSeq X 10B (300 cycles) = $3.54/Gb
December 3, 2024 at 12:20 PM
In #NextGenSequencing news, updated the #NGS #specs w/ two upcoming Illumina $ILMN NovaSeqX 25B kits, for 100cycles and 200cycles.
Now the cheapest $/Gb short-read runs are:
(1) NovaSeq X 25B (300 cycles) = $2.22/Gb
(2) NovaSeq X 25B (200 cycles) = $2.72/Gb
(3) NovaSeq X 10B (300 cycles) = $3.54/Gb
Now the cheapest $/Gb short-read runs are:
(1) NovaSeq X 25B (300 cycles) = $2.22/Gb
(2) NovaSeq X 25B (200 cycles) = $2.72/Gb
(3) NovaSeq X 10B (300 cycles) = $3.54/Gb
In #NextGenSequencing news, MGI Tech (Complete Genomics in the US) is running a promotion on their DNBSEQ-G99 sequencer. In many ways, this sequencer is the predecessor of Illumina's Miseq i100 refresh, which happened a couple of months ago.
December 5, 2024 at 10:43 AM
In #NextGenSequencing news, MGI Tech (Complete Genomics in the US) is running a promotion on their DNBSEQ-G99 sequencer. In many ways, this sequencer is the predecessor of Illumina's Miseq i100 refresh, which happened a couple of months ago.
Also, the second #NGS instrument to have a face after the NovaSeqX. #NGS #NextGenSequencing #ShortReads #MGI #Illumina #NovaSeqX #Emoticons #Emoji
February 28, 2025 at 9:18 AM
Also, the second #NGS instrument to have a face after the NovaSeqX. #NGS #NextGenSequencing #ShortReads #MGI #Illumina #NovaSeqX #Emoticons #Emoji
In #NextGenSequencing news, Oxford @nanoporetech.com has released a new version of their basecalling software with new functionalities. An explainer ow what the basecalling software is and what this new release brings for ONT users.
github.com/nanoporetech...
github.com/nanoporetech...
Release v0.9.0 · nanoporetech/dorado
[0.9.0] (16 Dec 2024)
This major release of Dorado introduces several new features and enhancements. The polish command, currently experimental, is optimised for refining draft assemblies of human ...
github.com
December 17, 2024 at 12:09 PM
In #NextGenSequencing news, Oxford @nanoporetech.com has released a new version of their basecalling software with new functionalities. An explainer ow what the basecalling software is and what this new release brings for ONT users.
github.com/nanoporetech...
github.com/nanoporetech...
#NextGenSequencing Is Q40 the new Q30? We've lived a couple of decades of NGS were the mark for "good quality reads" was at Q30, or equivalently, one error in every 1,000 bases.
But recently, companies like @elembio.bsky.social have changed the status quo of what people consider high quality NGS...
But recently, companies like @elembio.bsky.social have changed the status quo of what people consider high quality NGS...
December 13, 2024 at 4:56 PM
#NextGenSequencing Is Q40 the new Q30? We've lived a couple of decades of NGS were the mark for "good quality reads" was at Q30, or equivalently, one error in every 1,000 bases.
But recently, companies like @elembio.bsky.social have changed the status quo of what people consider high quality NGS...
But recently, companies like @elembio.bsky.social have changed the status quo of what people consider high quality NGS...
In #NextGenSequencing news, @elembio.bsky.social will start shipping Trinity enrichment kits in early December. Pre-orders are being accepted now. The support team is available to discuss the specifics of your panel and the recommended assay conditions.
December 18, 2024 at 10:09 AM
In #NextGenSequencing news, @elembio.bsky.social will start shipping Trinity enrichment kits in early December. Pre-orders are being accepted now. The support team is available to discuss the specifics of your panel and the recommended assay conditions.
More insightful discussions on the Roche SBX #NextGenSequencing platform, which was properly unveiled a few weeks ago.
Read length: I think the main inefficiency here might be the synthesis part, where if you start with a 5000bp molecule, only the first 500-1000bps are "expanded".
Read length: I think the main inefficiency here might be the synthesis part, where if you start with a 5000bp molecule, only the first 500-1000bps are "expanded".
Key questions for me are:
1) Read length - how long can these actually get before they tangle, fracture or crash out of solution?
2) Raw error rate - how accurate can the novel polymerases get?
3) Is there any plausible pathway to detecting modified bases?
March 5, 2025 at 9:07 AM
More insightful discussions on the Roche SBX #NextGenSequencing platform, which was properly unveiled a few weeks ago.
Read length: I think the main inefficiency here might be the synthesis part, where if you start with a 5000bp molecule, only the first 500-1000bps are "expanded".
Read length: I think the main inefficiency here might be the synthesis part, where if you start with a 5000bp molecule, only the first 500-1000bps are "expanded".
In #NextGenSequencing news, Illumina has started selling the non-Plus version of their low-throughput MiSeq i100 instrument, which comes at a list price of $49k. This is similar to the MiSeq i100 Plus version but cannot perform 100M runs.
August 12, 2025 at 11:54 AM
In #NextGenSequencing news, Illumina has started selling the non-Plus version of their low-throughput MiSeq i100 instrument, which comes at a list price of $49k. This is similar to the MiSeq i100 Plus version but cannot perform 100M runs.
In #NextGenSequencing news, we are starting to see accounts on real customers using the new Illumina $ILMN MiSeq i100 sequencer. One of the selling points of this instrument is that it is easy to use, and produces same-day results. The reports tell about being able to go from a library in a tube...
December 12, 2024 at 4:58 PM
In #NextGenSequencing news, we are starting to see accounts on real customers using the new Illumina $ILMN MiSeq i100 sequencer. One of the selling points of this instrument is that it is easy to use, and produces same-day results. The reports tell about being able to go from a library in a tube...
In #NextGenSequencing news, Oxford @nanoporetech.com has announced a 5% rise in prices across the board, and a gradual phasing out of their quasi-zero CAPEX "starter kit" model towards a low-CAPEX instrument model.
For example, their MinION is going from $2K starter pack minimum to a $5K minimum.
For example, their MinION is going from $2K starter pack minimum to a $5K minimum.
January 8, 2025 at 5:16 PM
In #NextGenSequencing news, Oxford @nanoporetech.com has announced a 5% rise in prices across the board, and a gradual phasing out of their quasi-zero CAPEX "starter kit" model towards a low-CAPEX instrument model.
For example, their MinION is going from $2K starter pack minimum to a $5K minimum.
For example, their MinION is going from $2K starter pack minimum to a $5K minimum.
Illumina AGBT25 update. Positive progress on innovation, but everything new is 18 months away. open.substack.com/pub/albertvi... #NGS #NextGenSequencing #Multiomics
Illumina AGBT25 update
Positive progress on innovation, but everything is 18 months away.
open.substack.com
February 28, 2025 at 8:59 AM
Illumina AGBT25 update. Positive progress on innovation, but everything new is 18 months away. open.substack.com/pub/albertvi... #NGS #NextGenSequencing #Multiomics
In #NextGenSequencing news, Dante Labs is to stop operating, many employees have now been let go, some not paid since as far back as March 2024.
Whole Genome Sequencing | Dante Labs World
We offer whole genome sequencing to help you understand your health, lifestyle, and the risk of inheriting diseases. Simple, clear, and personal reports.
www.dantelabs.com
December 4, 2024 at 10:34 AM
In #NextGenSequencing news, Dante Labs is to stop operating, many employees have now been let go, some not paid since as far back as March 2024.
In #NextGenSequencing news, Oxford @nanoporetech.com has released a new version of their basecaller. This release of Dorado brings significant basecalling speed improvements for Nvidia GPUs such as Ampere – e.g., RTX A6000, the Orin line, and the Ada Lovelace product line. github.com/nanoporetech...
Release v0.9.1 · nanoporetech/dorado
[0.9.1] (21 Jan 2025)
This release of Dorado brings significant basecalling speed improvements for Nvidia GPUs with compute capabilities 8.6 (Ampere – e.g., RTX A6000), 8.7 (Ampere – e.g., Orin fam...
github.com
January 22, 2025 at 10:43 AM
In #NextGenSequencing news, Oxford @nanoporetech.com has released a new version of their basecaller. This release of Dorado brings significant basecalling speed improvements for Nvidia GPUs such as Ampere – e.g., RTX A6000, the Orin line, and the Ada Lovelace product line. github.com/nanoporetech...
On #NationalHotTeaDay, we highlight how #genomics is transforming tea research. From uncovering unique flavors to improving cultivation, Novogene’s sequencing solutions empower tea science.
Read more in our blog: bit.ly/41GIPdb
#TeaResearch #NextGenSequencing #ScienceForAgriculture #Novogene
Read more in our blog: bit.ly/41GIPdb
#TeaResearch #NextGenSequencing #ScienceForAgriculture #Novogene
January 12, 2025 at 10:12 AM
On #NationalHotTeaDay, we highlight how #genomics is transforming tea research. From uncovering unique flavors to improving cultivation, Novogene’s sequencing solutions empower tea science.
Read more in our blog: bit.ly/41GIPdb
#TeaResearch #NextGenSequencing #ScienceForAgriculture #Novogene
Read more in our blog: bit.ly/41GIPdb
#TeaResearch #NextGenSequencing #ScienceForAgriculture #Novogene