#OffTarget
My top three pieces of advice to PR people are: Get to the point, get to the point, get to the point: https://mitchwagner.com/2026/09/17/my-top-three-pieces-of.html
My top three pieces of advice to PR people are: Get to the point, get to the point, get to the point
After more than two years at Fierce Network, my email address has finally gotten out to the directories that PR agencies buy, and I’m now getting literally dozens of pitches a day. Many of them are outrageously offtarget – I seem to have gotten on lists for healthcare, for job-hunting advice, and I get a small flow of emails from someone pitching interviews with a guy who claims to have resolved the apparent discrepancies between science and all the world’s religions. I don’t even look at the bodies of my emails anymore. I just look at the subject lines and senders. If neither of those catch my eye, I’m moving on. I’m not saying this to complain. I have a great job. When I see my colleagues complaining on LinkedIn about PR people, I cringe so hard I strain a muscle. Literally billions of people in the world would gladly change places with any one of us. I’m just saying that if you’re a PR person pitching me – or any journalist or analyst – get to the point, get to the point, get to the point. PS Religion and science cannot be reconciled, but they are complementary. Faith is belief in the absence of evidence. Faith and science solve different problems. As for reconciling the different religions of the world: As a species, we’ve been fighting wars over that for at least 4,000 years. Maybe you can solve that problem, but I doubt it.
mitchwagner.com
September 17, 2026 at 9:16 PM
A study in Environment International shows the importance of shifting away from #pesticides linked to #health consequences for #residential #communities exposed as a result of #offtarget #drift. University of Arizona Harvard T.H. Chan School of Public Health ➡️ Daily News: https://ow.ly/V5AW50ZM1bl
Gestational Diabetes Elevated in Pregnancies of Women Exposed to Pesticides - Beyond Pesticides Daily News Blog
A study demonstrates a connection between off-target pesticides and gestational diabetes in at-risk communities.
ow.ly
September 10, 2026 at 4:01 PM
🇳🇿🇦🇺ANZ MONTHLY KINDLE DEAL ALERT🇦🇺🇳🇿

This month we have FOUR @evesmithauthor.bsky.social books ON SALE😱 DOWNLOAD NOW!🙌

#OffTarget: 🔗https://amzn.asia/d/0gBtDc3P
#One: 🔗https://amzn.asia/d/0iNhlMHU
#TheWaitingRooms: 🔗https://amzn.asia/d/01brWshN
#TheCure: 🔗https://amzn.asia/d/09I0Yrk5
August 25, 2026 at 11:27 AM
Epigenetics Update - Widespread DNA off-targeting confounds RNA chromatin occupancy studies go.nature.com/3PmKDVa

Pieter Mestdagh (Ghent University) and igorulitsky.bsky.social (Weizmann Institute of Science) in natbiotech.nature.com

#Epigenetics #Chromatin #OffTarget
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epigenometech.com
Widespread DNA off-targeting confounds RNA chromatin occupancy studies - Nature Biotechnology
Many long noncoding RNA–DNA binding peaks detected using common assays arise from technical artifacts.
go.nature.com
May 19, 2026 at 11:22 AM
🇨🇦🇺🇸ATTENTION USA & CANADA🇺🇸🇨🇦

#OffTarget, the CHILLING #SpeculativeThriller by BESTSELLING AUTHOR @evesmithauthor.bsky.social
is on SALE NOW for just $0.99 on #kindle in the USA and Canada for the month of February❄️

You won’t want to miss this deal😍

🔗https://a.co/d/0g835Haf
February 17, 2026 at 4:19 PM
## Hyperdimensional Bayesian Inference for Minimizing CRISPR-Cas9 Off-Target Effects via Predictive Genome Sequencing (HBIM-offTARGET)

**Abstract:** CRISPR-Cas9 gene editing holds immense therapeutic potential, but off-target effects remain a significant challenge hindering clinical translation.…
## Hyperdimensional Bayesian Inference for Minimizing CRISPR-Cas9 Off-Target Effects via Predictive Genome Sequencing (HBIM-offTARGET)
**Abstract:** CRISPR-Cas9 gene editing holds immense therapeutic potential, but off-target effects remain a significant challenge hindering clinical translation. This paper proposes Hyperdimensional Bayesian Inference for Minimizing Off-Target Effects (HBIM-offTARGET), a novel framework leveraging hyperdimensional computing (HDC) and Bayesian inference to predict and mitigate off-target events. HBIM-offTARGET constructs a high-dimensional representation of the genome sequence, integrates experimentally-derived off-target activity data, and predicts susceptibility to off-target cleavage with unprecedented accuracy.
freederia.com
November 29, 2025 at 10:55 PM
Jared Offtarget
November 17, 2025 at 4:35 AM
💉#UK #eBook #DEALS!🏥

THREE of @evesmithauthor.bsky.social's high-stakes, eerily prescient #Speculative #Thrillers are ALL on #Sale for #99p each on Apple! 💉

👁️ #ONE - bit.ly/4gt9QpR
👶 #OffTarget - bit.ly/46fY8du
🏥 #TheWaitingRooms - bit.ly/46pl2iW

#BookSky #Dystopian #Thriller
September 17, 2025 at 12:50 PM
FFS, you're kidding! Argh, I listened to two of those topics in background - YouTube autoplay..

Actually thought they were good - offtarget on some of the Oz-China details but overall good.

🙄 YouTube two hop strikes again.
September 7, 2025 at 7:42 AM
Let’s be clear about what’s really going on over at Target. They’re playing us.

The current CEO, will “step down,” but he’s moving up to exec chair of the Board of Directors. That’s rewarding his failure.

The new CEO, is the current COO & has been w/Target for 20 years.

Nothing’s really changing.
August 23, 2025 at 3:33 PM
This isn’t even a recently adjudicated case. They’re tryna pretend like they did something but the only newsworthy tidbit here is another defendant was just sentenced. Not the Jeffrey Epstein case but they’re talking about some other child rapists.

www.justice.gov/opa/pr/opera...

#offtarget
Operation Grayskull Culminates in Lengthy Sentences for Managers of Dark Web Site Dedicated to Sexual Abuse of Children
Today, the Justice Department announced the results of Operation Grayskull, a highly successful joint effort between the Department of Justice and the FBI that resulted in the dismantling of four dark...
www.justice.gov
July 28, 2025 at 1:14 PM
May 29, 2025 at 8:01 PM
Major retailers like Shamazon, Costco, Wallyworld, Offtarget were starting to stockpile back in Nov. They've been continuing to max out their warehousing capacity. Even leasing additional space. Rather than tariff revenue, the result will be empty shelves and consumers relying on personal stockpiles
April 28, 2025 at 11:08 AM
Yes #OffTarget is great! Let them wither
can’t believe i never realized what a great hashtag #OffTarget would be for this effort until months in
April 25, 2025 at 1:42 AM
can’t believe i never realized what a great hashtag #OffTarget would be for this effort until months in
April 25, 2025 at 1:24 AM
I haven’t been to #target since they flipped. Who else? #offtarget
April 12, 2025 at 2:03 PM
PRICE DROP! 👀

@evesmithauthor.bsky.social's terrifyingly captivating #Thriller #OffTarget is on #SALE!

A startlingly thought-provoking thriller that provides a chilling glimpse of a future that's just one modification away…

Kobo: bit.ly/451WnP6
Kindle: bit.ly/3SIQfHA

#ThrillerRecs #Books #DEAL
April 10, 2025 at 8:10 AM
There’s much more data in the paper, so please check it out! We also showed insertion by delivering RNA templates, insertion in different cell types, in vitro characterization of STITCHR, mapping of nicking sites, PacBio sequencing of long insertions, offtarget mapping and more
April 9, 2025 at 5:14 PM
Highlighst of the 2025 ThemeDay:
Congratulations to Masako Kaufmann @uni-freiburg.de for the best poster at the #DGGTeV #Themeday2025 for her work on #BaseEditing #offtarget detection via universal CAST-Seq
April 7, 2025 at 4:50 PM
March 11, 2025 at 6:18 AM
#CBQOTD
I need some stuff to listen to. So let's hear about some podcasts you like but really wouldn't recommend to people.
#acquiredtaste #offtarget #audience
March 3, 2025 at 4:21 PM
Mine too. #OffTarget
February 22, 2025 at 3:05 PM
Dear @Target, it’s not OK to allow people to openly carry guns in your stores! #OffTarget https://act.everytown.org/act/target-petition?source=twns_share&utm_source=tw_n_&utm_medium=_s&utm_campaign=share via @Everytown
Target: Create Gun Sense Policies in Your Stores
A serious line has been seriously crossed.
act.everytown.org
February 3, 2025 at 11:29 AM