🌟 On the 6th day of #OpenCRAVAT, my database gave to me…Six Gene-Level Insights!
Which insight is most valuable for your research? CHASMplus, REVEL, PolyPhen-2, @gnomad-project.bsky.social, ClinVar, or COSMIC?
Explore OpenCRAVAT at opencravat.org
#Genomics #VariantAnalysis #OpenCRAVAT 🧬 🖥️
Which insight is most valuable for your research? CHASMplus, REVEL, PolyPhen-2, @gnomad-project.bsky.social, ClinVar, or COSMIC?
Explore OpenCRAVAT at opencravat.org
#Genomics #VariantAnalysis #OpenCRAVAT 🧬 🖥️
December 7, 2024 at 3:45 AM
🌟 On the 6th day of #OpenCRAVAT, my database gave to me…Six Gene-Level Insights!
Which insight is most valuable for your research? CHASMplus, REVEL, PolyPhen-2, @gnomad-project.bsky.social, ClinVar, or COSMIC?
Explore OpenCRAVAT at opencravat.org
#Genomics #VariantAnalysis #OpenCRAVAT 🧬 🖥️
Which insight is most valuable for your research? CHASMplus, REVEL, PolyPhen-2, @gnomad-project.bsky.social, ClinVar, or COSMIC?
Explore OpenCRAVAT at opencravat.org
#Genomics #VariantAnalysis #OpenCRAVAT 🧬 🖥️
Help shape the future of genomic variant annotation! We’re looking for community contributors to support OpenCRAVAT — from testing new features to improving documentation and outreach.
📝 Sign up here: forms.gle/v5t2ErBxYzqn...
#Genomics #Bioinformatics #OpenScience #Annotation
📝 Sign up here: forms.gle/v5t2ErBxYzqn...
#Genomics #Bioinformatics #OpenScience #Annotation
OpenCRAVAT Community Contributor Interest Form
Help shape the future of genomic variant annotation! We’re looking for members of the genomics, bioinformatics, and clinical variant interpretation community to help improve OpenCRAVAT. As a…
forms.gle
August 15, 2025 at 3:43 PM
Help shape the future of genomic variant annotation! We’re looking for community contributors to support OpenCRAVAT — from testing new features to improving documentation and outreach.
📝 Sign up here: forms.gle/v5t2ErBxYzqn...
#Genomics #Bioinformatics #OpenScience #Annotation
📝 Sign up here: forms.gle/v5t2ErBxYzqn...
#Genomics #Bioinformatics #OpenScience #Annotation
Discover the latest updates and project status of OpenCRAVAT by exploring the roadmap available on GitHub. Stay informed about the progress and developments by visiting this link: [OpenCRAVAT Roadmap](github.com/orgs/Karchin...). #annotator #opencravat #bioinformatics #opensource #genomics 🧬 🧪 🖥️
OpenCRAVAT Roadmap • KarchinLab
This is the roadmap for the OpenCRAVAT Project.
github.com
October 16, 2025 at 10:01 PM
Discover the latest updates and project status of OpenCRAVAT by exploring the roadmap available on GitHub. Stay informed about the progress and developments by visiting this link: [OpenCRAVAT Roadmap](github.com/orgs/Karchin...). #annotator #opencravat #bioinformatics #opensource #genomics 🧬 🧪 🖥️
@moezdawood.bsky.social created the AllofUs 250k annotator for OpenCRAVAT to improve genomic research by integrating diverse data, including ancestry-specific allele frequencies. You can read more about Moez's experience developing the annotator here: www.opencravat.org/bringing-gen...
#opensource
#opensource
Bringing Genetic Diversity to the Forefront: Moez Dawood on the AllofUs 250k Annotator for OpenCRAVAT
Moez Dawood, an MD/PhD student at Baylor College of Medicine, has recently developed the AllofUs 250k annotator for OpenCRAVAT, a genomic annotation platform designed to handle both single variant…
www.opencravat.org
August 15, 2025 at 4:14 PM
@moezdawood.bsky.social created the AllofUs 250k annotator for OpenCRAVAT to improve genomic research by integrating diverse data, including ancestry-specific allele frequencies. You can read more about Moez's experience developing the annotator here: www.opencravat.org/bringing-gen...
#opensource
#opensource
☁️ Day 9 of #OpenCRAVAT: Run on the Cloud!
No hardware limits, no delays—just efficient genomic analysis anywhere. Learn how to set up OpenCRAVAT on the cloud today.
🔗Cloud Usage: https://buff.ly/3BjGavq
#12DaysofOpenCRAVAT #CloudComputing 🖥️ 🧬 #Genomics #Variants
No hardware limits, no delays—just efficient genomic analysis anywhere. Learn how to set up OpenCRAVAT on the cloud today.
🔗Cloud Usage: https://buff.ly/3BjGavq
#12DaysofOpenCRAVAT #CloudComputing 🖥️ 🧬 #Genomics #Variants
December 10, 2024 at 12:12 PM
☁️ Day 9 of #OpenCRAVAT: Run on the Cloud!
No hardware limits, no delays—just efficient genomic analysis anywhere. Learn how to set up OpenCRAVAT on the cloud today.
🔗Cloud Usage: https://buff.ly/3BjGavq
#12DaysofOpenCRAVAT #CloudComputing 🖥️ 🧬 #Genomics #Variants
No hardware limits, no delays—just efficient genomic analysis anywhere. Learn how to set up OpenCRAVAT on the cloud today.
🔗Cloud Usage: https://buff.ly/3BjGavq
#12DaysofOpenCRAVAT #CloudComputing 🖥️ 🧬 #Genomics #Variants
🧪 🧬 Want to explore your own genome?
Join our free webinar on how to use OpenCRAVAT to annotate & interpret your personal variants.
📅 July 10 | 🕐 1 PM EDT
🎙️ With Jasmine Baker, PhD & Rachel Karchin, PhD
🔗 tinyurl.com/3ur6vv35
#Genomics #Bioinformatics #OpenSource #OpenCRAVAT🖥️
Join our free webinar on how to use OpenCRAVAT to annotate & interpret your personal variants.
📅 July 10 | 🕐 1 PM EDT
🎙️ With Jasmine Baker, PhD & Rachel Karchin, PhD
🔗 tinyurl.com/3ur6vv35
#Genomics #Bioinformatics #OpenSource #OpenCRAVAT🖥️
Welcome! You are invited to join a webinar: Exploring Personal Genomes with OpenCRAVAT. After registering, you will receive a confirmation email about joining the webinar.
One-hour webinar teaching how to utilize OpenCRAVAT as an annotation tool for personal genomic data.
tinyurl.com
July 1, 2025 at 12:42 PM
🧪 🧬 Want to explore your own genome?
Join our free webinar on how to use OpenCRAVAT to annotate & interpret your personal variants.
📅 July 10 | 🕐 1 PM EDT
🎙️ With Jasmine Baker, PhD & Rachel Karchin, PhD
🔗 tinyurl.com/3ur6vv35
#Genomics #Bioinformatics #OpenSource #OpenCRAVAT🖥️
Join our free webinar on how to use OpenCRAVAT to annotate & interpret your personal variants.
📅 July 10 | 🕐 1 PM EDT
🎙️ With Jasmine Baker, PhD & Rachel Karchin, PhD
🔗 tinyurl.com/3ur6vv35
#Genomics #Bioinformatics #OpenSource #OpenCRAVAT🖥️
All OpenCRAVAT systems are back up!
January 6, 2025 at 4:29 PM
All OpenCRAVAT systems are back up!
🌐 On the 10th day of #OpenCRAVAT, my workflow gave to me…
✨ Powerful API Capabilities!
Integrate OpenCRAVAT into pipelines: submit jobs, check statuses, and fetch custom reports programmatically.
Explore the API docs: https://buff.ly/4g8lMfP
#12DaysofOpenCRAVAT #Genomics
✨ Powerful API Capabilities!
Integrate OpenCRAVAT into pipelines: submit jobs, check statuses, and fetch custom reports programmatically.
Explore the API docs: https://buff.ly/4g8lMfP
#12DaysofOpenCRAVAT #Genomics
December 10, 2024 at 12:19 PM
🌐 On the 10th day of #OpenCRAVAT, my workflow gave to me…
✨ Powerful API Capabilities!
Integrate OpenCRAVAT into pipelines: submit jobs, check statuses, and fetch custom reports programmatically.
Explore the API docs: https://buff.ly/4g8lMfP
#12DaysofOpenCRAVAT #Genomics
✨ Powerful API Capabilities!
Integrate OpenCRAVAT into pipelines: submit jobs, check statuses, and fetch custom reports programmatically.
Explore the API docs: https://buff.ly/4g8lMfP
#12DaysofOpenCRAVAT #Genomics
Starting December 1st, we’re launching the 12 Days of OpenCRAVAT—an adventurer’s guide to mastering genomic variant analysis. Each day, discover powerful tools, tips, and features designed to make your research faster, easier, and more insightful.
#12DaysofOpenCRAVAT #Genomics #VariantAnnotation
#12DaysofOpenCRAVAT #Genomics #VariantAnnotation
November 30, 2024 at 8:15 PM
Starting December 1st, we’re launching the 12 Days of OpenCRAVAT—an adventurer’s guide to mastering genomic variant analysis. Each day, discover powerful tools, tips, and features designed to make your research faster, easier, and more insightful.
#12DaysofOpenCRAVAT #Genomics #VariantAnnotation
#12DaysofOpenCRAVAT #Genomics #VariantAnnotation
Need variant annotation fast? OpenCRAVAT makes it easy—whether you're analyzing one variant or thousands. Free, flexible, and built for discovery. Try it today at opencravat.org 🧪🖥🧬
OpenCRAVAT
mouse
www.opencravat.org
April 18, 2025 at 3:14 AM
Need variant annotation fast? OpenCRAVAT makes it easy—whether you're analyzing one variant or thousands. Free, flexible, and built for discovery. Try it today at opencravat.org 🧪🖥🧬
🎁 On the 2nd day of #OpenCRAVAT, my software gave to me…
✨ Two New Example Inputs!
Test OpenCRAVAT with hgvs and dbsnp inputs. Perfect for trying the software before running your data!
🔗https://buff.ly/3BapIgP & https://buff.ly/49l5yNJ
#12DaysofOpenCRAVAT #VariantAnnotation
✨ Two New Example Inputs!
Test OpenCRAVAT with hgvs and dbsnp inputs. Perfect for trying the software before running your data!
🔗https://buff.ly/3BapIgP & https://buff.ly/49l5yNJ
#12DaysofOpenCRAVAT #VariantAnnotation
December 2, 2024 at 11:30 PM
🎁 On the 2nd day of #OpenCRAVAT, my software gave to me…
✨ Two New Example Inputs!
Test OpenCRAVAT with hgvs and dbsnp inputs. Perfect for trying the software before running your data!
🔗https://buff.ly/3BapIgP & https://buff.ly/49l5yNJ
#12DaysofOpenCRAVAT #VariantAnnotation
✨ Two New Example Inputs!
Test OpenCRAVAT with hgvs and dbsnp inputs. Perfect for trying the software before running your data!
🔗https://buff.ly/3BapIgP & https://buff.ly/49l5yNJ
#12DaysofOpenCRAVAT #VariantAnnotation
Introducing our latest offering: the Calibrated Classification Package for clinical interpretation of variant effect predictor scores. This innovative package aids users in applying ACMG/AMP variant interpretation guidelines.#annotator #opencravat #bioinformatics #opensource #genomics 🧬 🧪 🖥️
August 22, 2025 at 8:51 PM
Introducing our latest offering: the Calibrated Classification Package for clinical interpretation of variant effect predictor scores. This innovative package aids users in applying ACMG/AMP variant interpretation guidelines.#annotator #opencravat #bioinformatics #opensource #genomics 🧬 🧪 🖥️
; (3) run non-sensitive analyses locally and scale compute in cloud for bulk jobs; (4) automate QC and reporting templates; (5) train non-programmer staff using the GUI. #annotator #opencravat #bioinformatics #opensource #genomics
September 19, 2025 at 3:35 PM
; (3) run non-sensitive analyses locally and scale compute in cloud for bulk jobs; (4) automate QC and reporting templates; (5) train non-programmer staff using the GUI. #annotator #opencravat #bioinformatics #opensource #genomics
🧬 🖥OpenCRAVAT will integrate the All of Us dataset. That's BILLIONS of gene variation annotations for better understanding our DNA.
Check out the blog: www.opencravat.org/opencravat-i...
Preprint coming soon from @moezdawood.bsky.social
Check out the blog: www.opencravat.org/opencravat-i...
Preprint coming soon from @moezdawood.bsky.social
OpenCRAVAT Integrates All of Us Dataset for Variant Annotation
At ACMG 2025, Dr. Moez Dawood announced a groundbreaking initiative: the global democratization of deidentified allele count and frequency data from the first ~250,000 short-read Whole Genome…
www.opencravat.org
March 28, 2025 at 3:09 AM
🧬 🖥OpenCRAVAT will integrate the All of Us dataset. That's BILLIONS of gene variation annotations for better understanding our DNA.
Check out the blog: www.opencravat.org/opencravat-i...
Preprint coming soon from @moezdawood.bsky.social
Check out the blog: www.opencravat.org/opencravat-i...
Preprint coming soon from @moezdawood.bsky.social
Attending #ISMB2024 ? Meet @KarchinRachel and learn about @OpenCRAVAT workflows. Poster 449 July 15 bit.ly/3xVBGtb
ISCB
bit.ly
July 14, 2024 at 7:37 PM
Attending #ISMB2024 ? Meet @KarchinRachel and learn about @OpenCRAVAT workflows. Poster 449 July 15 bit.ly/3xVBGtb
🧬 New Blog by Dr. Rachel Karchin!
Dr. Karchin shares how OpenCRAVAT and CIViC are addressing transparency and interpretability in variant effect predictors. Discover how calibrated predictors are transforming clinical variant classification. 🖥️ 🔗 Read the full post:
Dr. Karchin shares how OpenCRAVAT and CIViC are addressing transparency and interpretability in variant effect predictors. Discover how calibrated predictors are transforming clinical variant classification. 🖥️ 🔗 Read the full post:
Variant effect predictors in the clinic: Working with calibrated predictors in OpenCRAVAT
Computational methods for predicting the effects of genetic variants are used by clinicians for interpreting genetic test results and by researchers for scientific exploration. However, their utility…
buff.ly
December 10, 2024 at 12:46 PM
🧬 New Blog by Dr. Rachel Karchin!
Dr. Karchin shares how OpenCRAVAT and CIViC are addressing transparency and interpretability in variant effect predictors. Discover how calibrated predictors are transforming clinical variant classification. 🖥️ 🔗 Read the full post:
Dr. Karchin shares how OpenCRAVAT and CIViC are addressing transparency and interpretability in variant effect predictors. Discover how calibrated predictors are transforming clinical variant classification. 🖥️ 🔗 Read the full post:
Have you seen our updated website? Head over to opencravat.org and check it out! 🖥🧪
OpenCRAVAT
mouse
buff.ly
January 19, 2025 at 10:14 PM
Have you seen our updated website? Head over to opencravat.org and check it out! 🖥🧪
🎄 On the 1st day of #OpenCRAVAT, my analysis gave to me…
✨ A Single Variant Tool for Free!
Quickly annotate any genomic variant right from the new OpenCRAVAT website. Try it now and simplify your workflows!
www.opencravat.org run.opencravat.org/webapps/vari...
✨ A Single Variant Tool for Free!
Quickly annotate any genomic variant right from the new OpenCRAVAT website. Try it now and simplify your workflows!
www.opencravat.org run.opencravat.org/webapps/vari...
December 1, 2024 at 8:14 PM
🎄 On the 1st day of #OpenCRAVAT, my analysis gave to me…
✨ A Single Variant Tool for Free!
Quickly annotate any genomic variant right from the new OpenCRAVAT website. Try it now and simplify your workflows!
www.opencravat.org run.opencravat.org/webapps/vari...
✨ A Single Variant Tool for Free!
Quickly annotate any genomic variant right from the new OpenCRAVAT website. Try it now and simplify your workflows!
www.opencravat.org run.opencravat.org/webapps/vari...
Day 7: Personalize your analysis with OpenCRAVAT! Access numerous annotation tools and refine your focus on certain genes or variants using filters. Automate tasks with Python scripts. Choose input formats.. Export results. Try it locally or in the cloud. #Genomics #VariantAnalysis
December 7, 2024 at 8:41 PM
Day 7: Personalize your analysis with OpenCRAVAT! Access numerous annotation tools and refine your focus on certain genes or variants using filters. Automate tasks with Python scripts. Choose input formats.. Export results. Try it locally or in the cloud. #Genomics #VariantAnalysis
We’ve integrated the data for annotation of YOUR exomes and genomes into widely used mass annotators:
📌 ANNOVAR (Kai Wang)
📌 dbNSFP (Xiaoming Liu)
📌 Ensembl VEP (@malloryfreeberg.bsky.social; @ensembl.bsky.social; web interface coming soon!)
📌 OpenCRAVAT (@opencravat.bsky.social; Rachel Karchin)
📌 ANNOVAR (Kai Wang)
📌 dbNSFP (Xiaoming Liu)
📌 Ensembl VEP (@malloryfreeberg.bsky.social; @ensembl.bsky.social; web interface coming soon!)
📌 OpenCRAVAT (@opencravat.bsky.social; Rachel Karchin)
March 21, 2025 at 2:21 PM
We’ve integrated the data for annotation of YOUR exomes and genomes into widely used mass annotators:
📌 ANNOVAR (Kai Wang)
📌 dbNSFP (Xiaoming Liu)
📌 Ensembl VEP (@malloryfreeberg.bsky.social; @ensembl.bsky.social; web interface coming soon!)
📌 OpenCRAVAT (@opencravat.bsky.social; Rachel Karchin)
📌 ANNOVAR (Kai Wang)
📌 dbNSFP (Xiaoming Liu)
📌 Ensembl VEP (@malloryfreeberg.bsky.social; @ensembl.bsky.social; web interface coming soon!)
📌 OpenCRAVAT (@opencravat.bsky.social; Rachel Karchin)
Actully yes. I began with investigating my own DNA sequence using bioinformatic tools, so nowadays it ia inseparable part of diagnostics and R&D.
Examples of tools which I have used:
-Golden Helix GenomeBrowse
-OpenCravat
-AlphaFold
-DynaMut
And plan to learn molecular dynamics simulation.
Examples of tools which I have used:
-Golden Helix GenomeBrowse
-OpenCravat
-AlphaFold
-DynaMut
And plan to learn molecular dynamics simulation.
December 25, 2024 at 10:33 AM
Actully yes. I began with investigating my own DNA sequence using bioinformatic tools, so nowadays it ia inseparable part of diagnostics and R&D.
Examples of tools which I have used:
-Golden Helix GenomeBrowse
-OpenCravat
-AlphaFold
-DynaMut
And plan to learn molecular dynamics simulation.
Examples of tools which I have used:
-Golden Helix GenomeBrowse
-OpenCravat
-AlphaFold
-DynaMut
And plan to learn molecular dynamics simulation.
Exciting news! OpenCRAVAT has a brand-new website AND logo. Check it out at opencravat.org.
🧬 Explore our Single Variant Tool directly on the landing page—annotate a single variant with ease and see how OpenCRAVAT simplifies genomic analysis! 🚀
#Genomics #VariantAnalysis #OpenCRAVAT
🧬 Explore our Single Variant Tool directly on the landing page—annotate a single variant with ease and see how OpenCRAVAT simplifies genomic analysis! 🚀
#Genomics #VariantAnalysis #OpenCRAVAT
OpenCRAVAT
opencravat.org
November 21, 2024 at 11:36 PM
Exciting news! OpenCRAVAT has a brand-new website AND logo. Check it out at opencravat.org.
🧬 Explore our Single Variant Tool directly on the landing page—annotate a single variant with ease and see how OpenCRAVAT simplifies genomic analysis! 🚀
#Genomics #VariantAnalysis #OpenCRAVAT
🧬 Explore our Single Variant Tool directly on the landing page—annotate a single variant with ease and see how OpenCRAVAT simplifies genomic analysis! 🚀
#Genomics #VariantAnalysis #OpenCRAVAT
We are planning to launch a new collection of Jupyter notebooks and would love to know if you're interested. If so, please share topics or features you'd like included. Your feedback will help us tailor these notebooks to your needs and preferences.#annotator #opencravat #opensource 🧬 🧪 🖥️
August 23, 2025 at 2:30 PM
We are planning to launch a new collection of Jupyter notebooks and would love to know if you're interested. If so, please share topics or features you'd like included. Your feedback will help us tailor these notebooks to your needs and preferences.#annotator #opencravat #opensource 🧬 🧪 🖥️
❗We are experiencing a power outage at our data center due to the polar vortex. All OpenCRAVAT systems are currently down. We will update as systems come back online.
January 6, 2025 at 2:37 PM
❗We are experiencing a power outage at our data center due to the polar vortex. All OpenCRAVAT systems are currently down. We will update as systems come back online.
Would you be interested in organizing or speaking at meetups, writing blog posts, or promoting the project?
Are you part of any communities or organizations where you could share our project?
#annotator #opencravat #bioinformatics #opensource #genomics
Are you part of any communities or organizations where you could share our project?
#annotator #opencravat #bioinformatics #opensource #genomics
July 7, 2025 at 7:01 PM
Would you be interested in organizing or speaking at meetups, writing blog posts, or promoting the project?
Are you part of any communities or organizations where you could share our project?
#annotator #opencravat #bioinformatics #opensource #genomics
Are you part of any communities or organizations where you could share our project?
#annotator #opencravat #bioinformatics #opensource #genomics