#OptimalTransport
STORIES
SpatioTemporal Omics eneRgIES

Learning Waddington epigenetic (+regulon) landscape from multi-time-point Stereo-seq #SpatialTranscriptomics

Fused Gromov-Wasserstein #OptimalTransport
Linear▶️gene expression error
Quadratic▶️spatial consistency

bioRxiv 2025
www.biorxiv.org/content/10.1...
July 6, 2025 at 11:28 AM
SIMO
Integration of multimodal single-cell omics (incld SNARE-seq ISSAAC-seq) with #SpatialTranscriptomics

Modality-specific kNN + fused G-W #OptimalTransport

vs CARD LIGER Scanorama Seurat Tangram

Spatial ATAC-RNAseq
Spatial CUT&TAG-RNAseq

#NatComm 2025
www.nature.com/articles/s41...
May 16, 2025 at 12:15 PM
Multiomics single-cell optimal transport
moscot.spatiotemporal

#OptimalTransport-based common coordinate framework

Map & align #SpatialTranscriptomics with single-cell data

scalable for millions of cells across multiple time points

vs Tangram gimVI

#Nature 2025
www.nature.com/articles/s41...
April 4, 2025 at 11:12 AM
PASTE2

Partial alignment (based on a subset of spots) of multi-slice #SpatialTranscriptomics

3D reconstruction of 16-slide Stereo-seq Drosophila embryo

Partial fused Gromov-Wasserstein #OptimalTransport

vs PASTE Pamona Tangram

#GenomeRes 2023
genome.cshlp.org/content/33/7...
March 22, 2025 at 11:11 AM
If you're @neuripsconf.bsky.social and into #OptimalTransport & bio, dont miss on Alice Driessen's spotlight talk on #ConditionalMongeGap for modeling CAR Response. Today #AIDrugX workshop!

Positive results on OOD perturbations -> accurate gene expression prediction. Paper: ibm.biz/carot-pre
December 15, 2024 at 9:29 PM
"Fast unsupervised ground metric learning with tree-Wasserstein distance" The method reduces computational complexity and enables scalable clustering applications in single-cell RNA sequencing. #MachineLearning #WassersteinDistance #OptimalTransport
Fast unsupervised ground metric learning with tree-Wasserstein distance
The performance of unsupervised methods such as clustering depends on the choice of distance metric between features, or ground metric. Commonly, ground metrics are decided with heuristics or learned…
arxiv.org
July 21, 2026 at 6:52 PM
Löst ein offenes Problem in der Quanteninformationstheorie durch den Beweis der Dreiecksungleichung für separable Quanten-Optimaltransport-Abstände und etabliert echte Metriken auf Quantenzustandsräumen mittels konvexer Dualität und Hermitescher Operator-Interpolationstechniken.
Metrizität des separablen Quanten-Optimaltransports mit Hilbert-Schmidt-Kosten
arxiv.org
September 4, 2026 at 2:40 AM
New geometric framework deforming quantum state transport by complexity metrics. Theorem connects optimal transport on von Neumann algebras to right-invariant metrics on unitary groups, with exact Bell/GHZ state preparation costs.

#QuantumControl #OptimalTransport #QuantumComplexity
Arnold-Nielsen Geometry for Complexity-Deformed Noncommutative Transport
arxiv.org
July 23, 2026 at 4:43 AM
A new monograph merges reproducing kernel Hilbert space theory with optimal transport, delivering tools for AI, physics‑informed modeling, reinforcement learning and finance. Read more: https://getnews.me/unified-kernel-methods-bridge-ai-physics-and-finance/ #rkhs #optimaltransport
October 8, 2025 at 11:58 AM
Researchers proposed an amortized method that approximates convex conjugates for Wasserstein‑2 transport, improving map quality. The latest version posted on 5 Oct 2025. Read more: https://getnews.me/amortized-convex-conjugates-boost-wasserstein-2-optimal-transport/ #optimaltransport #wasserstein2
October 8, 2025 at 10:59 AM
Researchers propose structural causal optimal transport, adding a regularization term that turns DRO into a difference‑of‑convex program and yields a tighter ambiguity set. https://getnews.me/structural-causal-optimal-transport-improves-distributionally-robust-optimization/ #optimaltransport #robust
October 2, 2025 at 11:47 PM
Researchers introduced an all‑to‑all flow model that learns optimal transport, reducing cost on synthetic benchmarks, ML datasets and chemical databases. Read more: https://getnews.me/flow-model-enables-pairwise-optimal-transport-for-conditional-transfer/ #optimaltransport #flowmodel
October 1, 2025 at 1:34 PM
Fused Partial Gromov‑Wasserstein (FPGW) removes the equal‑mass constraint and offers Frank‑Wolfe and Sinkhorn‑type solvers for efficient graph comparison. Read more: https://getnews.me/partial-gromov-wasserstein-method-boosts-unbalanced-graph-comparison/ #graphcomparison #optimaltransport
September 29, 2025 at 8:06 PM
A new double‑sliced Wasserstein metric speeds up meta‑measure comparisons, avoids high‑order moments and improves stability. Posted 26 Sep 2025. Read more: https://getnews.me/double-sliced-wasserstein-metric-improves-meta-measure-comparisons/ #doubleslicedwasserstein #metameasure #optimaltransport
September 29, 2025 at 12:06 PM
A polynomial‑time optimal transport algorithm for high‑dimensional product and Gaussian distributions runs in expected time poly(n/ε) and achieves squared distance O(log 1/ε). Read more: https://getnews.me/new-algorithmic-advances-in-high-dimensional-optimal-transport/ #optimaltransport #gaussian
September 29, 2025 at 5:54 AM
Optimal Transport improves handwritten text recognition in low‑resource settings, delivering consistent accuracy gains on benchmark tests with few labeled samples. Read more: https://getnews.me/optimal-transport-boosts-handwritten-text-recognition-in-low-resource-settings/ #htrecog #optimaltransport
September 24, 2025 at 4:08 PM
The paper adds an L₂‑entropy term to optimal transport, creating a finite‑dimensional particle control method that yields uniformly sampled reachable sets. https://getnews.me/entropy-regularized-method-for-uniform-sampling-of-reachable-sets/ #entropyregularization #optimaltransport #reachablesets
September 22, 2025 at 5:46 PM
Sparsity‑aware optimal transport (SOT) improves unsupervised image restoration, achieving perceptual scores in super‑resolution, deraining and dehazing than standard OT. Read more: https://getnews.me/sparsity-aware-optimal-transport-boosts-unsupervised-restoration/ #optimaltransport #unsupervised
September 18, 2025 at 8:01 PM
¡Compactación 3DGS definitiva! 🚀 GHAP reduce hasta 10 veces el número de Gaussians manteniendo calidad SOTA. Más velocidad y eficiencia en renderizado 3D real-time. ¡Descubre la ciencia tras Optimal Transport! 👇 youtu.be/jwSewI0F81w
#3DGS #GaussianSplatting #OptimalTransport
GHAP: 3D Gaussian Splatting 10X más RÁPIDO sin perder calidad (Optimal Transport)
YouTube video by En la mente de la máquina, Inteligencia Artificial
youtu.be
November 29, 2025 at 7:07 AM
Unified geometric framework using Wasserstein-2 optimal transport bounds entropy production across classical, discrete, and quantum systems; extends to Hamiltonian dynamics and connects optimal transport to counterdiabatic control protocols.

#QuantumThermodynamics #QuantumControl #OptimalTransport
Wasserstein-2 Geometry of Entropy Production in Classical and Quantum Stochastic Thermodynamics
arxiv.org
June 2, 2026 at 11:32 AM
Imaging Data-based Model Description Combining OptimalTransport and Phase-field Model https://www.biorxiv.org/content/10.64898/2025.11.30.691255v1
December 2, 2025 at 7:48 PM
Imaging Data-based Model Description Combining OptimalTransport and Phase-field Model https://www.biorxiv.org/content/10.64898/2025.11.30.691255v1
December 2, 2025 at 7:48 PM
MultistageOT: Multistage optimal transport infers trajectories from a snapshot of single-cell data.
Dahlin, Joakim S et al.
Paper
Details
#SingleCell #OptimalTransport #TrajectoryInference
December 16, 2025 at 9:02 AM