#PNH?🩸
🩸 Paroxysmal nocturnal hemoglobinuria (PNH):

Lack of GPI anchors ➡️ lack of CD55 & CD59 ➡️ unregulated complement activity ➡️ Triad: hemolysis, thrombosis, bone marrow failure (cytopenias)
#MedSky #IMsky #hemesky #PNH #thrombosis #theInternAtWork
November 26, 2024 at 3:22 AM
🩸 We extend our gratitude to our Silver-Level Sponsor, Bristol Myers Squibb (@bmsnews.bsky.social ), for supporting the HemeHub Hematology Summit on October 3!

🌐 Explore more: hemehub.org/events/hemeh...

#HemeHub #HemeOnc #HematologySummit #Myelofibrosis #MultipleMyeloma #CLL #PNH
September 30, 2026 at 2:35 AM
🩸The HemeHub Hematology Summit is just 2 days away!

Here’s a preview of the schedule, bringing together expert insights and panel discussions for a full day of learning!

Full program and event details: hemehub.org/events/hemeh...

#HemeHub #HemeOnc #Myelofibrosis #MultipleMyeloma #CLL #PNH #DLBCL
October 2, 2026 at 12:47 AM
What are the adverse events associated with proximal and terminal complement inhibition in patients with PNH?🩸

Watch our interview from #IPIG2025 with ‪Benjamin Chin-Yee (@bc-y.bsky.social‬) to find out:

👉 buff.ly/DCfWF6o 👈

#RareDisease #PNH #Hematology #BloodSky #HemeSky #MedSky
May 28, 2025 at 12:42 PM
🌟 𝐃𝐢𝐝 𝐲𝐨𝐮 𝐤𝐧𝐨𝐰? Today is Global PNH Awareness Day!
Let’s raise awareness for paroxysmal nocturnal hemoglobinuria (PNH), support patients, and action treatment access for all! 💙🩸

#PNHAwareness2025 #PNH #RareDisease #PatientSupport"
October 12, 2025 at 8:01 AM
Want to learn about the prevention of thrombosis in patients with PNH?🩸

Make sure to watch our recent interview from #IPIG2025 with @marrow.bsky.social‬ of @petermaccc.bsky.social‬ in which he discusses this:

🎥 buff.ly/i8Ry0Zr

#RareDisease #Hematology #Thrombosis #BloodSky #MedSky
June 9, 2025 at 4:05 PM
🩸 Facts about PNH & Breakthrough Hemolysis:

PNH RBC classification (Type I–III), Type III complement sensitivity, flow cytometry in diagnosis, granulocyte clone accuracy, and EVH control with danicopan.

#PNH #FlowCytometry #Granulocytes #Hematology #HemeOnc #Danicopan #RareDisease #MedEd #HEMEHUB
May 16, 2026 at 8:31 PM
Study highlights the incorporation of Eculizumab into the Brazilian public health system (SUS) in 2018 for Paroxysmal Nocturnal Hemoglobinuria (PNH)🩸.
Access requires strict criteria (e.g., LDH ≥ 1.5x UL). A crucial advance for patients!
🔓Full article at doi.org/10.46765/267...

#SUS #Brazil
October 28, 2025 at 1:27 PM
Tomorrow is #WorldBloodDonorDay! 🩸
Blood donations are vital for people with PNH and many others. If you're able, consider donating — it truly makes a difference.
#DonateBlood #PNH #PNHCommunity #BloodDonation
June 13, 2025 at 12:58 PM
7/ Hypercoagulable state

- Primary: inherited thrombophilias, APLAS
- Secondary: 
🩸 Increase in prothrombotic factors: pregnancy, OCP use, or other ⬆️estrogen state
🩸 Loss of natural anticoagulants: cirrhosis, nephrotic syndrome
🩸 PNH, MPNs, certain leukemias/lymphomas
March 19, 2025 at 11:08 AM
🩸 𝐃𝐢𝐝 𝐲𝐨𝐮 𝐤𝐧𝐨𝐰 about Extravascular Hemolysis (EVH) in #PNH?
It can occur on C5-inhibitor treatment, PNH symptoms return as red blood cells are destroyed outside blood vessels.

📖 Fattizzo et al. Blood 2025 doi: doi.org/10.1182/bloo...

#PNHAwareness2025 #DidYouKnow #KnowPNH
September 29, 2025 at 7:01 AM
🩸Join us for an expert-led session with Dr. Ilene Weitz and Dr. Taha Bat, featuring patient case discussions on #PNH and recent clinical breakthroughs in disease management.

⮕ Register: hemehub.org/live-webinars
⮕ Submit your cases: hemehub.org/case-submiss...

#Hematology #BloodDisorders #HEMEHUB
April 27, 2026 at 7:46 PM
On #WorldCancerDay, we stood with everyone affected by cancer. 🎗️ Did you know PNH is linked to bone marrow disorders that may increase bone cancer risk, like AML? Early detection is key! PNH Global Alliance advocates for regular screenings & care. 🩸 #PNHAwareness #BoneMarrowHealth
February 7, 2025 at 4:29 PM
What’s new in #PNH?🩸

This week's podcast episode highlights key takeaways from #IPIG2025, including challenging clinical scenarios & valuable insights from the COMMODORE trials.

🎧 Click here to listen:
👉 ow.ly/I5a550W5nvb

#Hematology #RareDisease #CTSM #TrialUpdate
June 6, 2025 at 11:34 AM
🩸 Facts about #PNH & Breakthrough Hemolysis:

Alternative pathway tick-over (C3), C5a-driven inflammation in #BTH, pregnancy as a complement trigger, #crovalimab SC dosing, and #LDH targets with terminal inhibition.

#ComplementSystem #C3 #C5a #Hematology #HemeOnc #RareDiseases #MedEd #HEMEHUB
May 18, 2026 at 9:06 PM
🩸Join us for an expert-led session with Dr. Ilene Weitz and Dr. Taha Bat, featuring patient case discussions on #PNH and recent clinical breakthroughs in disease management.

⮕ Register: hemehub.org/live-webinars
⮕ Submit your cases: hemehub.org/case-submiss...

#Hematology #BloodDisorders #HEMEHUB
April 11, 2026 at 9:48 PM
PNH is a rare acquired clonal hematopoietic stem cell disorder.🩸

Learn about the biology, diagnosis, & treatment of this non-malignant disease in our new article, featuring interviews with leading experts Austin Kulasekararaj, Catherine Flynn, & Jens Panse!

Click here:
🔗 buff.ly/WRSulMR

#MedSky
October 6, 2025 at 3:03 PM
Ignoring PNH isn’t an option. Without treatment, risks rise fast:
🫁 50% develop Pulmonary Hypertension
⚠️ 40% face deadly blood clots
❤️ 20% die from heart issues
🚨 65% have kidney damage
🩸 VTE risk is 62x higher
🔬 Clone growth = 4x clot risk
Early care saves lives!
May 9, 2025 at 2:42 PM
Being sick with a life threatening blood disease & insurance denying your 17k lifesaving pill to get your bone marrow working again makes you really think about who you really want in your life during these times.

Not people who make excuses for this administration.

🩸 #PNH #MakeMedsCostLessAgain
January 24, 2025 at 11:53 PM
🩸📢 The links for the HemeHub Hematology Summit have been updated!

Registration: hemehub.org/events/hemeh...

Full program and event details:
hemehub.org/events/hemeh...

🗓️ October 3, 2026
📍 Gaylord Texan Resort & Convention Center

#HemeHub #HemeOnc #Myelofibrosis #MultipleMyeloma #CLL #PNH #DLBCL
🩸📢 Join us for the HemeHub Hematology Summit on October 3, 2026, at the Gaylord Texan Resort!

Featuring panel moderators Adeel Khan, MD, MPH, MS, Elif Yilmaz, MD, Sayeef Mirza, MD, MPH and Ibrahim Ibrahim, MD.

Register: hemehub.org/events/hemat...

#HemeHub #HemeOnc #MultipleMyeloma #CLL #Lymphoma
September 8, 2026 at 2:09 AM
🩸 HemeHub is honored to welcome Ilene C. Weitz, MD, to our Scientific Advisory Board.

Dr. Weitz is a Professor of Medicine at USC with expertise in hematology, PNH, and complement disorders. We’re proud to have her expertise supporting HemeHub’s mission.

#HemeHub #Hematology #PNH #Thrombosis
August 11, 2026 at 2:01 AM
🩸 Bridging evidence, expertise, and clinical practice in #hematology!

Registration: hemehub.org/hybrid-event...

Full program and event details: hemehub.org/hybrid-event...

#HemeHub #Myelofibrosis #MultipleMyeloma #CLL #PNH #DLBCL #FollicularLymphoma #Lymphoma #PolycythemiaVera #CML #ITP
🩸Registration is now open for the #HemeHub Hematology Summit on October 3, 2026!

Explore the latest #hematology updates with leading experts sharing practical insights on #lymphoma, #myeloma, #CML, #myelofibrosis, #PNH, #ITP, and more.

🌐 Program details: hemehub.org/hybrid-event...
August 6, 2026 at 9:16 PM
🩸Registration is now open for the #HemeHub Hematology Summit on October 3, 2026!

Explore the latest #hematology updates with leading experts sharing practical insights on #lymphoma, #myeloma, #CML, #myelofibrosis, #PNH, #ITP, and more.

🌐 Program details: hemehub.org/hybrid-event...
July 9, 2026 at 7:55 PM
🩸 Facts about #PNH & Breakthrough Hemolysis:

Survival outcomes, #BTH definition variability, biosimilars, and next-generation complement inhibitors.

#ComplementSystem #C5Inhibition #BoneMarrowFailure #Thrombosis #Hemolysis #RenalFailure #Hematology #HemeOnc #MedicalEducation #MedEd #HEMEHUB
May 28, 2026 at 7:46 PM
May 26, 2026 at 2:59 PM