Lack of GPI anchors ➡️ lack of CD55 & CD59 ➡️ unregulated complement activity ➡️ Triad: hemolysis, thrombosis, bone marrow failure (cytopenias)
#MedSky #IMsky #hemesky #PNH #thrombosis #theInternAtWork
Lack of GPI anchors ➡️ lack of CD55 & CD59 ➡️ unregulated complement activity ➡️ Triad: hemolysis, thrombosis, bone marrow failure (cytopenias)
#MedSky #IMsky #hemesky #PNH #thrombosis #theInternAtWork
🌐 Explore more: hemehub.org/events/hemeh...
#HemeHub #HemeOnc #HematologySummit #Myelofibrosis #MultipleMyeloma #CLL #PNH
🌐 Explore more: hemehub.org/events/hemeh...
#HemeHub #HemeOnc #HematologySummit #Myelofibrosis #MultipleMyeloma #CLL #PNH
Here’s a preview of the schedule, bringing together expert insights and panel discussions for a full day of learning!
Full program and event details: hemehub.org/events/hemeh...
#HemeHub #HemeOnc #Myelofibrosis #MultipleMyeloma #CLL #PNH #DLBCL
Here’s a preview of the schedule, bringing together expert insights and panel discussions for a full day of learning!
Full program and event details: hemehub.org/events/hemeh...
#HemeHub #HemeOnc #Myelofibrosis #MultipleMyeloma #CLL #PNH #DLBCL
Watch our interview from #IPIG2025 with Benjamin Chin-Yee (@bc-y.bsky.social) to find out:
👉 buff.ly/DCfWF6o 👈
#RareDisease #PNH #Hematology #BloodSky #HemeSky #MedSky
Watch our interview from #IPIG2025 with Benjamin Chin-Yee (@bc-y.bsky.social) to find out:
👉 buff.ly/DCfWF6o 👈
#RareDisease #PNH #Hematology #BloodSky #HemeSky #MedSky
Let’s raise awareness for paroxysmal nocturnal hemoglobinuria (PNH), support patients, and action treatment access for all! 💙🩸
#PNHAwareness2025 #PNH #RareDisease #PatientSupport"
Let’s raise awareness for paroxysmal nocturnal hemoglobinuria (PNH), support patients, and action treatment access for all! 💙🩸
#PNHAwareness2025 #PNH #RareDisease #PatientSupport"
Make sure to watch our recent interview from #IPIG2025 with @marrow.bsky.social of @petermaccc.bsky.social in which he discusses this:
🎥 buff.ly/i8Ry0Zr
#RareDisease #Hematology #Thrombosis #BloodSky #MedSky
Make sure to watch our recent interview from #IPIG2025 with @marrow.bsky.social of @petermaccc.bsky.social in which he discusses this:
🎥 buff.ly/i8Ry0Zr
#RareDisease #Hematology #Thrombosis #BloodSky #MedSky
PNH RBC classification (Type I–III), Type III complement sensitivity, flow cytometry in diagnosis, granulocyte clone accuracy, and EVH control with danicopan.
#PNH #FlowCytometry #Granulocytes #Hematology #HemeOnc #Danicopan #RareDisease #MedEd #HEMEHUB
PNH RBC classification (Type I–III), Type III complement sensitivity, flow cytometry in diagnosis, granulocyte clone accuracy, and EVH control with danicopan.
#PNH #FlowCytometry #Granulocytes #Hematology #HemeOnc #Danicopan #RareDisease #MedEd #HEMEHUB
Access requires strict criteria (e.g., LDH ≥ 1.5x UL). A crucial advance for patients!
🔓Full article at doi.org/10.46765/267...
#SUS #Brazil
Access requires strict criteria (e.g., LDH ≥ 1.5x UL). A crucial advance for patients!
🔓Full article at doi.org/10.46765/267...
#SUS #Brazil
Blood donations are vital for people with PNH and many others. If you're able, consider donating — it truly makes a difference.
#DonateBlood #PNH #PNHCommunity #BloodDonation
Blood donations are vital for people with PNH and many others. If you're able, consider donating — it truly makes a difference.
#DonateBlood #PNH #PNHCommunity #BloodDonation
- Primary: inherited thrombophilias, APLAS
- Secondary:
🩸 Increase in prothrombotic factors: pregnancy, OCP use, or other ⬆️estrogen state
🩸 Loss of natural anticoagulants: cirrhosis, nephrotic syndrome
🩸 PNH, MPNs, certain leukemias/lymphomas
- Primary: inherited thrombophilias, APLAS
- Secondary:
🩸 Increase in prothrombotic factors: pregnancy, OCP use, or other ⬆️estrogen state
🩸 Loss of natural anticoagulants: cirrhosis, nephrotic syndrome
🩸 PNH, MPNs, certain leukemias/lymphomas
It can occur on C5-inhibitor treatment, PNH symptoms return as red blood cells are destroyed outside blood vessels.
📖 Fattizzo et al. Blood 2025 doi: doi.org/10.1182/bloo...
#PNHAwareness2025 #DidYouKnow #KnowPNH
It can occur on C5-inhibitor treatment, PNH symptoms return as red blood cells are destroyed outside blood vessels.
📖 Fattizzo et al. Blood 2025 doi: doi.org/10.1182/bloo...
#PNHAwareness2025 #DidYouKnow #KnowPNH
🔗Register: hemehub.org/live-webinars
💭Submit your cases: hemehub.org/case-submiss...
#PNH #Hematology #BloodDisorders #MedEd #HemeOnc #ClinicalCases #PatientCases #BloodCancer #HEMEHUB
@keckmedicineusc.bsky.social @utswim.bsky.social @rarediseaseadvisor.bsky.social
⮕ Register: hemehub.org/live-webinars
⮕ Submit your cases: hemehub.org/case-submiss...
#Hematology #BloodDisorders #HEMEHUB
🔗Register: hemehub.org/live-webinars
💭Submit your cases: hemehub.org/case-submiss...
#PNH #Hematology #BloodDisorders #MedEd #HemeOnc #ClinicalCases #PatientCases #BloodCancer #HEMEHUB
@keckmedicineusc.bsky.social @utswim.bsky.social @rarediseaseadvisor.bsky.social
This week's podcast episode highlights key takeaways from #IPIG2025, including challenging clinical scenarios & valuable insights from the COMMODORE trials.
🎧 Click here to listen:
👉 ow.ly/I5a550W5nvb
#Hematology #RareDisease #CTSM #TrialUpdate
This week's podcast episode highlights key takeaways from #IPIG2025, including challenging clinical scenarios & valuable insights from the COMMODORE trials.
🎧 Click here to listen:
👉 ow.ly/I5a550W5nvb
#Hematology #RareDisease #CTSM #TrialUpdate
Alternative pathway tick-over (C3), C5a-driven inflammation in #BTH, pregnancy as a complement trigger, #crovalimab SC dosing, and #LDH targets with terminal inhibition.
#ComplementSystem #C3 #C5a #Hematology #HemeOnc #RareDiseases #MedEd #HEMEHUB
Alternative pathway tick-over (C3), C5a-driven inflammation in #BTH, pregnancy as a complement trigger, #crovalimab SC dosing, and #LDH targets with terminal inhibition.
#ComplementSystem #C3 #C5a #Hematology #HemeOnc #RareDiseases #MedEd #HEMEHUB
⮕ Register: hemehub.org/live-webinars
⮕ Submit your cases: hemehub.org/case-submiss...
#Hematology #BloodDisorders #HEMEHUB
⮕ Register: hemehub.org/live-webinars
⮕ Submit your cases: hemehub.org/case-submiss...
#Hematology #BloodDisorders #HEMEHUB
Learn about the biology, diagnosis, & treatment of this non-malignant disease in our new article, featuring interviews with leading experts Austin Kulasekararaj, Catherine Flynn, & Jens Panse!
Click here:
🔗 buff.ly/WRSulMR
#MedSky
Learn about the biology, diagnosis, & treatment of this non-malignant disease in our new article, featuring interviews with leading experts Austin Kulasekararaj, Catherine Flynn, & Jens Panse!
Click here:
🔗 buff.ly/WRSulMR
#MedSky
🫁 50% develop Pulmonary Hypertension
⚠️ 40% face deadly blood clots
❤️ 20% die from heart issues
🚨 65% have kidney damage
🩸 VTE risk is 62x higher
🔬 Clone growth = 4x clot risk
Early care saves lives!
🫁 50% develop Pulmonary Hypertension
⚠️ 40% face deadly blood clots
❤️ 20% die from heart issues
🚨 65% have kidney damage
🩸 VTE risk is 62x higher
🔬 Clone growth = 4x clot risk
Early care saves lives!
Not people who make excuses for this administration.
🩸 #PNH #MakeMedsCostLessAgain
Not people who make excuses for this administration.
🩸 #PNH #MakeMedsCostLessAgain
Registration: hemehub.org/events/hemeh...
Full program and event details:
hemehub.org/events/hemeh...
🗓️ October 3, 2026
📍 Gaylord Texan Resort & Convention Center
#HemeHub #HemeOnc #Myelofibrosis #MultipleMyeloma #CLL #PNH #DLBCL
Featuring panel moderators Adeel Khan, MD, MPH, MS, Elif Yilmaz, MD, Sayeef Mirza, MD, MPH and Ibrahim Ibrahim, MD.
Register: hemehub.org/events/hemat...
#HemeHub #HemeOnc #MultipleMyeloma #CLL #Lymphoma
Registration: hemehub.org/events/hemeh...
Full program and event details:
hemehub.org/events/hemeh...
🗓️ October 3, 2026
📍 Gaylord Texan Resort & Convention Center
#HemeHub #HemeOnc #Myelofibrosis #MultipleMyeloma #CLL #PNH #DLBCL
Dr. Weitz is a Professor of Medicine at USC with expertise in hematology, PNH, and complement disorders. We’re proud to have her expertise supporting HemeHub’s mission.
#HemeHub #Hematology #PNH #Thrombosis
Dr. Weitz is a Professor of Medicine at USC with expertise in hematology, PNH, and complement disorders. We’re proud to have her expertise supporting HemeHub’s mission.
#HemeHub #Hematology #PNH #Thrombosis
Registration: hemehub.org/hybrid-event...
Full program and event details: hemehub.org/hybrid-event...
#HemeHub #Myelofibrosis #MultipleMyeloma #CLL #PNH #DLBCL #FollicularLymphoma #Lymphoma #PolycythemiaVera #CML #ITP
Explore the latest #hematology updates with leading experts sharing practical insights on #lymphoma, #myeloma, #CML, #myelofibrosis, #PNH, #ITP, and more.
🌐 Program details: hemehub.org/hybrid-event...
Registration: hemehub.org/hybrid-event...
Full program and event details: hemehub.org/hybrid-event...
#HemeHub #Myelofibrosis #MultipleMyeloma #CLL #PNH #DLBCL #FollicularLymphoma #Lymphoma #PolycythemiaVera #CML #ITP
Explore the latest #hematology updates with leading experts sharing practical insights on #lymphoma, #myeloma, #CML, #myelofibrosis, #PNH, #ITP, and more.
🌐 Program details: hemehub.org/hybrid-event...
Explore the latest #hematology updates with leading experts sharing practical insights on #lymphoma, #myeloma, #CML, #myelofibrosis, #PNH, #ITP, and more.
🌐 Program details: hemehub.org/hybrid-event...
Survival outcomes, #BTH definition variability, biosimilars, and next-generation complement inhibitors.
#ComplementSystem #C5Inhibition #BoneMarrowFailure #Thrombosis #Hemolysis #RenalFailure #Hematology #HemeOnc #MedicalEducation #MedEd #HEMEHUB
Survival outcomes, #BTH definition variability, biosimilars, and next-generation complement inhibitors.
#ComplementSystem #C5Inhibition #BoneMarrowFailure #Thrombosis #Hemolysis #RenalFailure #Hematology #HemeOnc #MedicalEducation #MedEd #HEMEHUB
Swipe to see the answers and explanations.
#PNH #Eculizumab #Ravulizumab #C5Inhibition #ComplementSystem #BreakthroughHemolysis #PKBreakthrough #Pregnancy #DrugClearance #PlasmaVolume #MaternalHealth #ThrombosisRisk #Hematology #HemeOnc #MedEd #HEMEHUB
Swipe to see the answers and explanations.
#PNH #Eculizumab #Ravulizumab #C5Inhibition #ComplementSystem #BreakthroughHemolysis #PKBreakthrough #Pregnancy #DrugClearance #PlasmaVolume #MaternalHealth #ThrombosisRisk #Hematology #HemeOnc #MedEd #HEMEHUB