Our findings suggest that #miR-10b-5p regulates early #adipogenesis by influencing cell fate bias toward the #paraxialMesoderm lineage through modulation of the #Gata6 / #Bmp2 signaling axis.
#NTU_Metabolic #SHIMR_NTU
@ntumeta.bsky.social @mark-christian-lab.bsky.social @ntuyourlibrary.bsky.social

#CoarctationOfAorta
A developmental problem of #SmoothMuscleCell #BoundaryFormation?😃

"a border is formed at the interface b/w #CardiacNeuralCrest- derived SMCs in the 6th #PharyngealArchArtery & #ParaxialMesoderm -derived SMCs in the dorsal aorta"

#JDBMDPI 2025
www.mdpi.com/2221-3759/13...

#Pericyte progenitors #Zebrafish🐟

nkx3.1 marks early🧠 pericyte progenitor from #ParaxialMesoderm & #NeuralCrest

Ablating nkx3.1+ progeny 24~48hpf➡️
⏬Pericyte
Arterial mispatterning
⏫🧠hemorrhage

1/3🧵
Sarah Childs lab bioRxiv 2023
www.biorxiv.org/content/10.1...